Gabriel Ghiaur

Assistant Professor

20062019
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Fingerprint Dive into the research topics where Gabriel Ghiaur is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Hematopoietic Stem Cells Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Bone Marrow Medicine & Life Sciences
Tretinoin Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Hematopoiesis Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Residual Neoplasm Medicine & Life Sciences

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Research Output 2006 2019

Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction

Hambley, B. C., Norsworthy, K. J., Jasem, J., Zimmerman, J. W., Shenderov, E., Webster, J., Showel, M., Gondek, L., Dalton, W., Prince, G., Gladstone, D., Streiff, M. B., Pratz, K., Gojo, I., Ghiaur, G., Levis, M. J., Smith, B. D. & Dezern, A., Aug 1 2019, In : Leukemia Research. 83, 106174.

Research output: Contribution to journalLetter

Acute Promyelocytic Leukemia
Fibrinogen
Heparin
Hemorrhage

Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity

Li, L., Knutsdottir, H., Hui, K., Weiss, M. J., He, J., Philosophe, B., Cameron, A. M., Wolfgang, C., Pawlik, T. M., Ghiaur, G., Ewald, A., Mezey, E., Bader, J. S. & Selaru, F., Jan 24 2019, In : JCI Insight. 4, 2, Y.

Research output: Contribution to journalArticle

Open Access
Organoids
Liver Neoplasms
Pharmaceutical Preparations
Neoplasms
Drug Therapy

Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment

Su, M., Chang, Y. T., Hernandez, D., Jones, R. J. & Ghiaur, G., Jun 1 2019, In : Journal of Cellular and Molecular Medicine. 23, 6, p. 4111-4117 7 p.

Research output: Contribution to journalArticle

Open Access
Cytochrome P-450 CYP3A
Drug and Narcotic Control
Cytidine Deaminase
Acute Myeloid Leukemia
Bone Marrow

The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal Vitamin A homeostasis, but is required for exogenous atRA clearance

Zhong, G., Hogarth, C., Snyder, J. M., Palau, L., Topping, T., Huang, W., Czuba, L. C., LaFrance, J., Ghiaur, G. & Isoherranen, N., Jan 1 2019, In : Journal of Biological Chemistry. 294, 29, p. 11166-11179 14 p.

Research output: Contribution to journalArticle

Open Access
Mixed Function Oxygenases
Tretinoin
Vitamin A
Homeostasis
Tamoxifen

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3

Nagai, K., Hou, L., Li, L., Nguyen, B., Seale, T., Shirley, C., Ma, H., Levis, M. J., Ghiaur, G., Duffield, A. S. & Small, D., Aug 31 2018, In : Oncotarget. 9, 68, p. 32885-32899 15 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Leukemia
Acute Myeloid Leukemia
Acute Promyelocytic Leukemia
Ubiquitination