Frederick Lenz

Professor

1976 …2020
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Research Output 1976 2020

Single-neuron analysis of human thalamus in patients with intention tremor and other clinical signs of cerebellar disease

Lenz, F., Jaeger, C. J., Seike, M. S., Lin, Y. C. & Reich, S. G., 2002, In : Journal of Neurophysiology. 87, 4, p. 2084-2094 11 p.

Research output: Contribution to journalArticle

Cerebellar Diseases
Tremor
Thalamus
Neurons
Cerebellar Nuclei

Single unit analysis of the human ventral thalamic nuclear group: Activity correlated with movement

Lenz, F., Kwan, H. C., Dostrovsky, J. O., Tasker, R. R., Murphy, J. T. & Lenz, Y. E., Dec 1990, In : Brain. 113, 6, p. 1795-1821 27 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Neurons
Sensory feedback
Unit
Cell

Single unit analysis of the human ventral thalamic nuclear group: Tremor-related activity in functionally identified cells

Lenz, F., Kwan, H. C., Martin, R. L., Tasker, R. R., Dostrovsky, J. O. & Lenz, Y. E., Jun 1994, In : Brain. 117, 3, p. 531-543 13 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Cells
Unit
Cell

Single unit analysis of the human ventral thalamic nuclear group: Correlation of thalamic 'tremor cells' with the 3-6 Hz component of Parkinsonian tremor

Lenz, F., Tasker, R. R., Kwam, H. C., Schnider, S., Kwong, R., Murayama, Y., Dostrovsky, J. O. & Murphy, J. T., 1988, In : Journal of Neuroscience. 8, 3, p. 754-764 11 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Electromyography
Fingers
Signal-To-Noise Ratio

Single-unit analysis of the human ventral thalamic nuclear group: Somatosensory responses

Lenz, F., Dostrovsky, J. O., Tasker, R. R., Yamashiro, K., Kwan, H. C. & Murphy, J. T., 1988, In : Journal of Neurophysiology. 59, 2, p. 299-316 18 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Skin
Body Regions
Fingers
Elbow

Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

Muthuswamy, J., Tran, P., Rangarajan, R., Lenz, F., Hanley, D. F. & Thakor, N. V., Mar 12 1999, In : Neuroscience Letters. 262, 3, p. 191-194 4 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Thalamus
Evoked Potentials
barbituric acid

Spatial attention to thermal pain stimuli in subjects with visual spatial hemi-neglect: Extinction, mislocalization and misidentification of stimulus modality

Liu, C. C., Veldhuijzen, D. S., Ohara, S., Winberry, J., Greenspan, J. D. & Lenz, F., Mar 2011, In : Pain. 152, 3, p. 498-506 9 p.

Research output: Contribution to journalArticle

Hot Temperature
Pain
Psychological Extinction
Stroke
Control Groups

Spatial neglect during electrocortical stimulation mapping in the right hemisphere

Kleinman, J. T., Sepkuty, J. P., Hillis-Trupe, A., Lenz, F., Heidler-Gary, J., Gingis, L. & Crone, N. E., Dec 2007, In : Epilepsia. 48, 12, p. 2365-2368 4 p.

Research output: Contribution to journalArticle

Perceptual Disorders
Parietal Lobe
Temporal Lobe
Epilepsy
Electrodes

Speech recognition impairments in patients with intractable right temporal lobe epilepsy

Boatman, D. F., Lesser, R. P., Crone, N. E., Krauss, G., Lenz, F. & Miglioretti, D. L., Aug 2006, In : Epilepsia. 47, 8, p. 1397-1401 5 p.

Research output: Contribution to journalArticle

Temporal Lobe Epilepsy
Amobarbital
Partial Epilepsy
Patient Rights
Temporal Lobe

Spinal cord injury: A small step forward for spinal cord injury patients?

Anderson, W. S. & Lenz, F., Aug 2011, In : Nature Reviews Neurology. 7, 8, p. 422-423 2 p.

Research output: Contribution to journalArticle

Spinal Cord Stimulation
Spinal Cord Injuries
Cervical Cord

Spontaneous low threshold spike bursting in awake humans is different in different lateral thalamic nuclei

Ohara, S., Taghva, A., Kim, J. H. & Lenz, F., Jun 2007, In : Experimental Brain Research. 180, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

Lateral Thalamic Nuclei
Calcium Signaling
Neurons
Thalamic Diseases
Essential Tremor

Statistical modeling and analysis of laser-evoked potentials of electrocorticogram recordings from awake humans

Chen, Z., Ohara, S., Cao, J., Vialatte, F., Lenz, F. & Cichocki, A., 2007, In : Computational Intelligence and Neuroscience. 2007, 10479.

Research output: Contribution to journalArticle

Statistical Modeling
Bioelectric potentials
Statistical Analysis
Laser
Wavelet Analysis

Statistical prediction of the optimal site for thalamotomy in parkinsonian tremor

Lenz, F., Normand, S. L., Kwan, H. C., Andrews, D., Rowland, L. H., Jones, M. W., Seike, M., Lin, Y. C., Tasker, R. R., Dostrovsky, J. O. & Lenz, Y. E., 1995, In : Movement disorders : official journal of the Movement Disorder Society. 10, 3, p. 318-328 11 p.

Research output: Contribution to journalArticle

Tremor
Neurons
Thalamus
Therapeutics

Stereotactic ablative and stimulation procedures for treatment of movement disorders

Vitek, J. L., Lozano, A. M. & Lenz, F., Jun 1999, In : Neurosurgery Quarterly. 9, 2, p. 103-119 17 p.

Research output: Contribution to journalArticle

Movement Disorders
Deep Brain Stimulation
Tremor
Pallidotomy
Parkinson Disease

Stereotactic thalamotomy in the treatment of essential tremor of the upper extremity: Reassessment including a blinded measure of outcome

Zirh, A., Reich, S. G., Dougherty, P. M. & Lenz, F., Jun 1999, In : Journal of Neurology Neurosurgery and Psychiatry. 66, 6, p. 772-775 4 p.

Research output: Contribution to journalArticle

Essential Tremor
Handwriting
Upper Extremity
Tremor
Outcome Assessment (Health Care)

Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced pain

Lenz, F., Gracely, R. H., Romanoski, A. J., Hope, E. J., Rowland, L. H. & Dougherty, P. M., 1995, In : Nature Medicine. 1, 9, p. 910-913 4 p.

Research output: Contribution to journalArticle

Thalamus
Chemical activation
Pain
Panic Disorder
Tremor

Stroke of bad luck?

Kim, E. H., Chien, J. H., Liu, C. C., Oishi, K., Oishi, K., Sebastian, R., Demsky, C., Lenz, F. & Hillis-Trupe, A., Jan 2 2017, In : Neurocase. 23, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

Stroke
Skin
Emotions
Luck
Rating
Pain
Causality
Electrodes
Therapeutics
Epilepsy

Studies of the human ascending pain pathways

Weiss, N., Lawson, H. C., Greenspan, J. D., Ohara, S. & Lenz, F., Mar 2005, In : Thalamus and Related Systems. 3, 1, p. 71-86 16 p.

Research output: Contribution to journalArticle

Chronic Pain
Primates
Pain Clinics
Pain
Nociception

Surgery insight: Deep brain stimulation for movement disorders

Anderson, W. S. & Lenz, F., Jun 2006, In : Nature Clinical Practice Neurology. 2, 6, p. 310-320 11 p.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Movement Disorders
Parkinson Disease
Essential Tremor
Tourette Syndrome

Surgery of the motor thalamus: Problems with the present nomenclatures

Krack, P., Dostrovsky, J., Ilinsky, I., Kultas-Ilinsky, K., Lenz, F., Lozano, A. & Vitek, J., 2002, In : Movement disorders : official journal of the Movement Disorder Society. 17, SUPPL. 3

Research output: Contribution to journalArticle

Thalamus
Terminology
Haplorhini
Thalamic Nuclei
Atlases

Thalamic Burst Firing in Response to Experimental Pain Stimuli and in Patients with Chronic Neuropathic Pain may be a Carrier for Pain-Related Signals

Markman, T. M., Liu, C. C., Zhang, J. C., Kobayashi, K., Kim, J. H. & Lenz, F. A., Aug 2013, Chronic Pain and Brain Abnormalities. Elsevier Inc., p. 41-60 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuralgia
Chronic Pain
Lasers
Pain
Thalamus

Thalamic mechanisms of chest pain in the absence of cardiac pathology.

Lenz, F., Dougherty, P. M. & Traill, T. A., May 1996, In : Heart. 75, 5, p. 429-430 2 p.

Research output: Contribution to journalArticle

Microvascular Angina
Viscera
Chest Pain
Thalamus
Abdominal Pain

Thalamic mechanisms of pain and pain modulation

Lenz, F., 1993, In : European Journal of Pain (United Kingdom). 14, 2, p. 21-24 4 p.

Research output: Contribution to journalArticle

Pain

Thalamic microelectrode recording and microstimulation in central and deafferentation pain

Tasker, R. R., Gorecki, J., Lenz, F., Hirayama, T. & Dostrovsky, J. O., 1987, In : Applied Neurophysiology. 50, 1-6, p. 414-417 4 p.

Research output: Contribution to journalArticle

Microelectrodes
Pain
Referred Pain
Hyperalgesia
Human Body

Thalamic neuronal activity correlated with essential tremor

Hua, S. E., Lenz, F., Zirh, T. A., Reich, S. G. & Dougherty, P. M., Feb 1998, In : Journal of Neurology Neurosurgery and Psychiatry. 64, 2, p. 273-276 4 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Harmaline
Thalamus
Forearm

Thalamic neuronal and EMG activity in psychogenic dystonia compared with organic dystonia

Kobayashi, K., Lang, A. E., Hallett, M. & Lenz, F., Jun 2011, In : Movement disorders : official journal of the Movement Disorder Society. 26, 7, p. 1348-1352 5 p.

Research output: Contribution to journalArticle

Dystonic Disorders
Dystonia
Electromyography
Signal-To-Noise Ratio
Ventral Thalamic Nuclei

Thalamic physiology of intentional essential tremor is more like cerebellar tremor than postural essential tremor

Zakaria, R., Lenz, F., Hua, S., Avin, B. H., Liu, C. C. & Mari, Z., Sep 5 2013, In : Brain Research. 1529, p. 188-199 12 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Ventral Thalamic Nuclei
Cerebellar Diseases
Cerebellar Nuclei

Thalamic post-inhibitory bursting occurs in patients with organic dystonia more often than controls

Kobayashi, K., Liu, C. C., Jensen, A. L., Vitek, J. L., Mari, Z. & Lenz, F., Dec 6 2013, In : Brain Research. 1541, p. 81-91 11 p.

Research output: Contribution to journalArticle

Dystonia
Ventral Thalamic Nuclei
Dystonic Disorders
Signal-To-Noise Ratio
Haplorhini

Thalamic single neuron activity in patients with dystonia: Dystonia- related activity and somatic sensory reorganization

Lenz, F., Jaeger, C. J., Seike, M. S., Lin, Y. C., Reich, S. G., DeLong, M. R. & Vitek, J. L., 1999, In : Journal of Neurophysiology. 82, 5, p. 2372-2392 21 p.

Research output: Contribution to journalArticle

Dystonia
Neurons
Muscles
Joints
Muscle Contraction

Thalamic single neuron and electromyographic activities in patients with dystonia.

Zirh, T. A., Reich, S. G., Perry, V. & Lenz, F., 1998, In : Advances in neurology. 78, p. 27-32 6 p.

Research output: Contribution to journalArticle

Somatosensory Evoked Potentials
Dystonia
Microelectrodes
Electromyography
Thalamus

Thalamic single-unit activity occurring in patients with hemidystonia

Lenz, F., Martin, R., Kwan, H. C., Tasker, R. R. & Dostrovsky, J. O., 1990, In : Stereotactic and Functional Neurosurgery. 54, 1-8, p. 159-162 4 p.

Research output: Contribution to journalArticle

Dystonia
Dyskinesias
Thalamus
Upper Extremity

Thalamic stimulation and recording in patients with deafferentation and central pain

Gorecki, J., Hirayama, T., Dostrovsky, J. O., Tasker, R. R. & Lenz, F., 1989, In : Stereotactic and Functional Neurosurgery. 52, 2-4, p. 219-226 8 p.

Research output: Contribution to journalArticle

Hyperalgesia
Microelectrodes
Thalamus
Pain

Thalamotomy

von Coelln, R., Kobayashi, K., Kim, J. H., Anderson, W. S., Winberry, J. & Lenz, F. A., Jan 1 2010, Encyclopedia of Movement Disorders. Elsevier Inc., p. 226-229 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tremor
Ventral Thalamic Nuclei
Essential Tremor
Deep Brain Stimulation
Microelectrodes

The effect of cortical lesions on the electromyographic response to joint displacement in the squirrel monkey forelimb

Lenz, F., Tatton, W. G. & Tasker, R. R., 1983, In : Journal of Neuroscience. 3, 4, p. 795-805 11 p.

Research output: Contribution to journalArticle

Saimiri
Forelimb
Motor Cortex
Joints
Torque

The human pain system: Experimental and clinical perspectives

Lenz, F., Casey, K. L., Jones, E. G. & Willis, W. D., Oct 1 2010, Cambridge University Press. 638 p.

Research output: Book/ReportBook

Pain
Primates
Rodentia
Anatomy
Pharmacology

The human thalamic somatic sensory nucleus [Ventral caudal (Vc)] shows neuronal mechanoreceptor-like responses to optimal stimuli for peripheral mechanoreceptors

Weiss, N., Ohara, S., Johnson, K. O. & Lenz, F., Feb 2009, In : Journal of Neurophysiology. 101, 2, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

Mechanoreceptors
Pacinian Corpuscles
Neurons
Vibration
Skin

Thermal and pain sensations evoked by microstimulation in the area of human ventrocaudal nucleus

Lenz, F., Seike, M., Richardson, R. T., Lin, Y. C., Baker, F. H., Khoja, I., Jaeger, C. J. & Gracely, R. H., 1993, In : Journal of Neurophysiology. 70, 1, p. 200-210 11 p.

Research output: Contribution to journalArticle

Hot Temperature
Pain
Skin
Referred Pain
Metatarsophalangeal Joint

The role of feedback in the tremor frequency activity of tremor cells in the ventral nuclear group of human thalamus.

Lenz, F., Schnider, S., Tasker, R. R., Kwong, R., Kwan, H., Dostrovsky, J. O. & Murphy, J. T., 1987, In : Acta Neurochirurgica, Supplement. 39, p. 54-56 3 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Thalamus

The role of the thalamus and basal ganglia in parkinsonian tremor

Hua, S., Reich, S. G., Zirh, A. T., Perry, V., Dougherty, P. M. & Lenz, F., 1998, In : Movement disorders : official journal of the Movement Disorder Society. 13, SUPPL. 3, p. 40-42 3 p.

Research output: Contribution to journalArticle

Tremor
Basal Ganglia
Thalamus
Sensory Feedback
Globus Pallidus

The sensation of angina can be evoked by stimulation of the human thalamus

Lenz, F., Gracely, R. H., Hope, E. J., Baker, F. H., Rowland, L. H., Dougherty, P. M. & Richardson, R. T., 1994, In : Pain. 59, 1, p. 119-125 7 p.

Research output: Contribution to journalArticle

Thalamus
Arachnoiditis
Unstable Angina
Wounds and Injuries
Thoracic Wall

The sensory-limbic model of pain memory: Connections from thalamus to the limbic system mediate the learned component of the affective dimension of pain

Casey, K. L., Ledoux, J., Gabriel, M., Lenz, F., Gracely, R. H., Zirh, A. T., Romanoski, A. J., Staats, P. & Dougherty, P. M., 1997, In : Pain Forum. 6, 1, p. 22-43 22 p.

Research output: Contribution to journalArticle

Limbic System
Thalamus
Pain
Somatosensory Cortex
Cerebral Cortex

The Thalamus

Chien, J. H., Cheng, J. J. & Lenz, F., Oct 11 2016, Conn's Translational Neuroscience. Elsevier Inc., p. 289-297 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Thalamus
Thalamic Nuclei
Wakefulness
Sleep Stages
Electrophysiology

The ventral posterior nucleus of thalamus is involved in the generation of central pain syndromes

Lenz, F., 1992, In : APS Journal. 1, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

Posterior Thalamic Nuclei
Ventral Thalamic Nuclei
Pain
Excitatory Amino Acids
Calcium

Transcortical sensory aphasia: Revisited and revised

Boatman, D. F., Gordon, B., Hart, J., Selnes, O., Miglioretti, D. & Lenz, F., Aug 2000, In : Brain. 123, 8, p. 1634-1642 9 p.

Research output: Contribution to journalArticle

Wernicke Aphasia
Language
Amobarbital
Phonetics
Semantics

Transcranial magnetic stimulation of the brain: Guidelines for pain treatment research

Klein, M. M., Treister, R., Raij, T., Pascual-Leone, A., Park, L., Nurmikko, T., Lenz, F., Lefaucheur, J. P., Lang, M., Hallett, M., Fox, M., Cudkowicz, M., Costello, A., Carr, D. B., Ayache, S. S. & Oaklander, A. L., Sep 1 2015, In : Pain. 156, 9, p. 1601-1614 14 p.

Research output: Contribution to journalArticle

Transcranial Magnetic Stimulation
Guidelines
Pain
Brain
Research

Transient inhibition of responses to thermal stimuli of spinal sensory tract neurons in monkeys during sensitization by intradermal capsaicin

Dougherty, P. M., Willis, W. D. & Lenz, F., Aug 1998, In : Pain. 77, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

Capsaicin
Sensory Receptor Cells
Haplorhini
Hyperalgesia
Hot Temperature

Transient unilateral hearing loss induced by electrocortical stimulation

Sinha, S. R., Crone, N. E., Fotta, R., Lenz, F. & Boatman, D. F., Jan 25 2005, In : Neurology. 64, 2, p. 383-385 3 p.

Research output: Contribution to journalArticle

Unilateral Hearing Loss
Temporal Lobe
Hearing
Ear
Seizures

Tremor-frequency (3-6 Hz) activity in the sensorimotor arm representation of the internal segment of the globus pallidus in patients with Parkinson's disease

Lemstra, A. W., Verhagen Metman, L., Lee, J. I., Dougherty, P. M. & Lenz, F., May 28 1999, In : Neuroscience Letters. 267, 2, p. 129-132 4 p.

Research output: Contribution to journalArticle

Globus Pallidus
Tremor
Parkinson Disease
Arm
Neurons

What can neuroimaging tell us about central pain?

Veldhuijzen, D. S., Lenz, F., Lagraize, S. C. & Greenspan, J. D., Jan 1 2009, Translational Pain Research: From Mouse to Man. CRC Press, p. 315-328 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuroimaging
Neurology
Pain
Central Nervous System