Frederick Lenz

Professor

1976 …2018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1976 2018

1998

Patterns of bursting occurring in thalamic cells during parkinsonian tremor

Zirh, T. A., Lenz, F., Reich, S. G. & Dougherty, P. M., Mar 1998, In : Neuroscience. 83, 1, p. 107-121 15 p.

Research output: Contribution to journalArticle

Tremor
Reflex
Deceleration
Thalamus
Ventral Thalamic Nuclei

Reorganization of sensory modalities evoked by microstimulation in region of the thalamic principal sensory nucleus in patients with pain due to nervous system injury

Lenz, F., Gracely, R. H., Baker, F. H., Richardson, R. T. & Dougherty, P. M., Sep 14 1998, In : Journal of Comparative Neurology. 399, 1, p. 125-138 14 p.

Research output: Contribution to journalArticle

Nervous System Trauma
Pain
Chronic Pain
Hot Temperature
Movement Disorders

Thalamic neuronal activity correlated with essential tremor

Hua, S. E., Lenz, F., Zirh, T. A., Reich, S. G. & Dougherty, P. M., Feb 1998, In : Journal of Neurology Neurosurgery and Psychiatry. 64, 2, p. 273-276 4 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Harmaline
Thalamus
Forearm

Thalamic single neuron and electromyographic activities in patients with dystonia.

Zirh, T. A., Reich, S. G., Perry, V. & Lenz, F., 1998, In : Advances in neurology. 78, p. 27-32 6 p.

Research output: Contribution to journalArticle

Somatosensory Evoked Potentials
Dystonia
Microelectrodes
Electromyography
Thalamus

The role of the thalamus and basal ganglia in parkinsonian tremor

Hua, S., Reich, S. G., Zirh, A. T., Perry, V., Dougherty, P. M. & Lenz, F., 1998, In : Movement disorders : official journal of the Movement Disorder Society. 13, SUPPL. 3, p. 40-42 3 p.

Research output: Contribution to journalArticle

Tremor
Basal Ganglia
Thalamus
Sensory Feedback
Globus Pallidus

Transient inhibition of responses to thermal stimuli of spinal sensory tract neurons in monkeys during sensitization by intradermal capsaicin

Dougherty, P. M., Willis, W. D. & Lenz, F., Aug 1998, In : Pain. 77, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

Capsaicin
Sensory Receptor Cells
Haplorhini
Hyperalgesia
Hot Temperature
1997

Correlation of effects of general anesthetics on somatosensory neurons in the primate thalamus and cortical EEG power

Dougherty, P. M., Li, Y. J., Lenz, F., Rowland, L. & Mittman, S. H., 1997, In : Journal of Neurophysiology. 77, 3, p. 1375-1392 18 p.

Research output: Contribution to journalArticle

General Anesthetics
Halothane
Methohexital
Thalamus
Primates

Human thalamic nucleus mediating taste and multiple other sensations related to ingestive behavior

Lenz, F., Gracely, R. H., Zirh, T. A., Leopold, D. A., Rowland, L. H. & Dougherty, P. M., 1997, In : Journal of Neurophysiology. 77, 6, p. 3406-3409 4 p.

Research output: Contribution to journalArticle

Thalamic Nuclei
Neurosurgical Procedures
Viscera
Smell
Primates

Microelectrode recording and stimulation techniques during stereotactic procedures in the thalamus and pallidum.

Mandir, A. S., Rowland, L. H., Dougherty, P. M. & Lenz, F., 1997, In : Advances in neurology. 74, p. 159-165 7 p.

Research output: Contribution to journalArticle

Stereotaxic Techniques
Neurosurgical Procedures
Globus Pallidus
Electrophysiology
Microelectrodes

Pallidotomy for hemiballismus: Efficacy and characteristics of neuronal activity

Suarez, J., Verhagen Merman, L., Reich, S. G., Dougherty, P. M., Hallett, M. & Lenz, F., Nov 1997, In : Annals of Neurology. 42, 5, p. 807-811 5 p.

Research output: Contribution to journalArticle

Pallidotomy
Dyskinesias
Globus Pallidus
Thalamus
Parkinson Disease

The sensory-limbic model of pain memory: Connections from thalamus to the limbic system mediate the learned component of the affective dimension of pain

Casey, K. L., Ledoux, J., Gabriel, M., Lenz, F., Gracely, R. H., Zirh, A. T., Romanoski, A. J., Staats, P. & Dougherty, P. M., 1997, In : Pain Forum. 6, 1, p. 22-43 22 p.

Research output: Contribution to journalArticle

Limbic System
Thalamus
Pain
Somatosensory Cortex
Cerebral Cortex
1996

Characterization of cortical spreading depression by imaging of intrinsic optical signals

Yoon, R. S., Tsang, P. W., Lenz, F. & Kwan, H. C., 1996, In : NeuroReport. 7, 15-17, p. 2671-2674 4 p.

Research output: Contribution to journalArticle

Cortical Spreading Depression
Optical Imaging
Cerebral Cortex
Sensorimotor Cortex

Evidence that excitatory amino acids mediate afferent input to the primate somatosensory thalamus

Dougherty, P. M., Li, Y. J., Lenz, F., Rowland, L. & Mittman, S. H., Jul 29 1996, In : Brain Research. 728, 2, p. 267-273 7 p.

Research output: Contribution to journalArticle

Excitatory Amino Acids
Thalamus
Primates
Neurons
Excitatory Amino Acid Agonists

Thalamic mechanisms of chest pain in the absence of cardiac pathology.

Lenz, F., Dougherty, P. M. & Traill, T. A., May 1996, In : Heart. 75, 5, p. 429-430 2 p.

Research output: Contribution to journalArticle

Microvascular Angina
Viscera
Chest Pain
Thalamus
Abdominal Pain
1995

Central post-stroke pain: a challenge for the scientist and the clinician

Jensen, T. S. & Lenz, F., 1995, In : Pain. 61, 2, p. 161-164 4 p.

Research output: Contribution to journalArticle

Thalamic Diseases
Cerebrovascular Disorders
Hypersensitivity
Stroke
Pain

Interactive image-guided neurosurgery.

Lenz, F. & Olivi, A., 1995, In : Neurosurgery. 36, 6, p. 1233 1 p.

Research output: Contribution to journalArticle

Neurosurgery

Statistical prediction of the optimal site for thalamotomy in parkinsonian tremor

Lenz, F., Normand, S. L., Kwan, H. C., Andrews, D., Rowland, L. H., Jones, M. W., Seike, M., Lin, Y. C., Tasker, R. R., Dostrovsky, J. O. & Lenz, Y. E., 1995, In : Movement disorders : official journal of the Movement Disorder Society. 10, 3, p. 318-328 11 p.

Research output: Contribution to journalArticle

Tremor
Neurons
Thalamus
Therapeutics

Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced pain

Lenz, F., Gracely, R. H., Romanoski, A. J., Hope, E. J., Rowland, L. H. & Dougherty, P. M., 1995, In : Nature Medicine. 1, 9, p. 910-913 4 p.

Research output: Contribution to journalArticle

Thalamus
Chemical activation
Pain
Panic Disorder
Tremor
1994

A population of cells in the human thalamic principal sensory nucleus respond to painful mechanical stimuli

Lenz, F., Gracely, R. H., Rowland, L. H. & Dougherty, P. M., Oct 10 1994, In : Neuroscience Letters. 180, 1, p. 46-50 5 p.

Research output: Contribution to journalArticle

Hyperalgesia
Acute Pain
Thalamus
Population
Hot Temperature

Characteristics of somatotopic organization and spontaneous neuronal activity in the region of the thalamic principal sensory nucleus in patients with spinal cord transection

Lenz, F., Kwan, H. C., Martin, R., Tasker, R., Richardson, R. T. & Dostrovsky, J. O., 1994, In : Journal of Neurophysiology. 72, 4, p. 1570-1587 18 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Movement Disorders
Thalamus
Neurons
Pain

Distribution and response evoked by microstimulation of thalamus nuclei in patients with dystonia and tremor.

Lin, Y. C. & Lenz, F., Apr 1994, In : Chinese Medical Journal. 107, 4, p. 265-270 6 p.

Research output: Contribution to journalArticle

Dystonia
Tremor
Thalamus
Paresthesia
Vertigo

Single unit analysis of the human ventral thalamic nuclear group: Tremor-related activity in functionally identified cells

Lenz, F., Kwan, H. C., Martin, R. L., Tasker, R. R., Dostrovsky, J. O. & Lenz, Y. E., Jun 1994, In : Brain. 117, 3, p. 531-543 13 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Cells
Unit
Cell

The sensation of angina can be evoked by stimulation of the human thalamus

Lenz, F., Gracely, R. H., Hope, E. J., Baker, F. H., Rowland, L. H., Dougherty, P. M. & Richardson, R. T., 1994, In : Pain. 59, 1, p. 119-125 7 p.

Research output: Contribution to journalArticle

Thalamus
Arachnoiditis
Unstable Angina
Wounds and Injuries
Thoracic Wall
1993

Effective response evoked by microstimulation of thalamus nuclei in patients with tremor.

Lin, Y. C. & Lenz, F., May 1993, In : Chinese Medical Journal. 106, 5, p. 372-374 3 p.

Research output: Contribution to journalArticle

Tremor
Thalamus
Paresthesia
Vertigo
Pain

Neurons in the area of human thalamic nucleus ventralis caudalis respond to painful heat stimuli

Lenz, F., Seike, M., Lin, Y. C., Baker, F. H., Rowland, L. H., Gracely, R. H. & Richardson, R. T., Oct 1 1993, In : Brain Research. 623, 2, p. 235-240 6 p.

Research output: Contribution to journalArticle

Thalamic Nuclei
Hot Temperature
Neurons
Skin
Pain

Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models

Lenz, F., Vitek, J. L. & DeLong, M. R., 1993, In : Stereotactic and Functional Neurosurgery. 60, 1-3, p. 94-103 10 p.

Research output: Contribution to journalArticle

Tremor
Thalamus
Primates
Basal Ganglia
Haplorhini

Thalamic mechanisms of pain and pain modulation

Lenz, F., 1993, In : European Journal of Pain (United Kingdom). 14, 2, p. 21-24 4 p.

Research output: Contribution to journalArticle

Pain

Thermal and pain sensations evoked by microstimulation in the area of human ventrocaudal nucleus

Lenz, F., Seike, M., Richardson, R. T., Lin, Y. C., Baker, F. H., Khoja, I., Jaeger, C. J. & Gracely, R. H., 1993, In : Journal of Neurophysiology. 70, 1, p. 200-210 11 p.

Research output: Contribution to journalArticle

Hot Temperature
Pain
Skin
Referred Pain
Metatarsophalangeal Joint
1992

The ventral posterior nucleus of thalamus is involved in the generation of central pain syndromes

Lenz, F., 1992, In : APS Journal. 1, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

Posterior Thalamic Nuclei
Ventral Thalamic Nuclei
Pain
Excitatory Amino Acids
Calcium
1990

Single unit analysis of the human ventral thalamic nuclear group: Activity correlated with movement

Lenz, F., Kwan, H. C., Dostrovsky, J. O., Tasker, R. R., Murphy, J. T. & Lenz, Y. E., Dec 1990, In : Brain. 113, 6, p. 1795-1821 27 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Neurons
Sensory feedback
Unit
Cell

Thalamic single-unit activity occurring in patients with hemidystonia

Lenz, F., Martin, R., Kwan, H. C., Tasker, R. R. & Dostrovsky, J. O., 1990, In : Stereotactic and Functional Neurosurgery. 54, 1-8, p. 159-162 4 p.

Research output: Contribution to journalArticle

Dystonia
Dyskinesias
Thalamus
Upper Extremity
1989

Characteristics of the bursting pattern of action potentials that occurs in the thalamus of patients with central pain

Lenz, F., Kwan, H. C., Dostrovsky, J. O. & Tasker, R. R., Sep 4 1989, In : Brain Research. 496, 1-2, p. 357-360 4 p.

Research output: Contribution to journalArticle

Thalamus
Action Potentials
Pain
Neurons
Thalamic Nuclei

Detection of feedback in the central nervous system using system identification techniques

Schnider, S. M., Kwong, R. H., Lenz, F. & Kwan, H. C., Jan 1989, In : Biological Cybernetics. 60, 3, p. 203-212 10 p.

Research output: Contribution to journalArticle

Neurology
Tremor
Identification (control systems)
Central Nervous System
Feedback

Recordings of abnormal activity in patients with deafferentation and central pain

Hirayama, T., Dostrovsky, J. O., Gorecki, J., Tasker, R. R. & Lenz, F., 1989, In : Stereotactic and Functional Neurosurgery. 52, 2-4, p. 120-126 7 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Pain

Thalamic stimulation and recording in patients with deafferentation and central pain

Gorecki, J., Hirayama, T., Dostrovsky, J. O., Tasker, R. R. & Lenz, F., 1989, In : Stereotactic and Functional Neurosurgery. 52, 2-4, p. 219-226 8 p.

Research output: Contribution to journalArticle

Hyperalgesia
Microelectrodes
Thalamus
Pain
1988

Methods for microstimulation and recording of single neurons and evoked potentials in the human central nervous system

Lenz, F., Dostrovsky, J. O., kwan, H. C., Tasker, R. R., Yamashiro, K. & Murphy, J. T., 1988, In : Journal of Neurosurgery. 68, 4, p. 630-634 5 p.

Research output: Contribution to journalArticle

Evoked Potentials
Central Nervous System
Neurons
Central Nervous System Diseases

Single unit analysis of the human ventral thalamic nuclear group: Correlation of thalamic 'tremor cells' with the 3-6 Hz component of Parkinsonian tremor

Lenz, F., Tasker, R. R., Kwam, H. C., Schnider, S., Kwong, R., Murayama, Y., Dostrovsky, J. O. & Murphy, J. T., 1988, In : Journal of Neuroscience. 8, 3, p. 754-764 11 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Electromyography
Fingers
Signal-To-Noise Ratio

Single-unit analysis of the human ventral thalamic nuclear group: Somatosensory responses

Lenz, F., Dostrovsky, J. O., Tasker, R. R., Yamashiro, K., Kwan, H. C. & Murphy, J. T., 1988, In : Journal of Neurophysiology. 59, 2, p. 299-316 18 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Skin
Body Regions
Fingers
Elbow
1987

Abnormal single-unit activity recorded in the somatosensory thalamus of a quadriplegic patient with central pain

Lenz, F., Tasker, R. R., Dostrovsky, J. O., Kwan, H. C., Gorecki, J., Hirayama, T. & Murphy, J. T., 1987, In : Pain. 31, 2, p. 225-236 12 p.

Research output: Contribution to journalArticle

Thalamus
Pain
Neck
Spinal Cord Injuries
Human Body

Long-latency reflex activity in squirrel monkeys with occlusion of the middle cerebral artery

Lenz, F., Tasker, R. R., Tatton, W. G. & Halliday, W., 1987, In : Electroencephalography and Clinical Neurophysiology. 67, 3, p. 238-246 9 p.

Research output: Contribution to journalArticle

Saimiri
Middle Cerebral Artery Infarction
Reflex
Middle Cerebral Artery
Torque

Microelectrode techniques in localization of stereotactic targets

Tasker, R. R., Lenz, F., Yamashiro, K., Gorecki, J., Hirayama, T. & Dostrovsky, J. O., 1987, In : Neurological Research. 9, 2, p. 105-112 8 p.

Research output: Contribution to journalArticle

Stereotaxic Techniques
Brain Mapping
Microelectrodes
Tremor
Thalamus

Selection of the optimal lesion site for the relief of parkinsonian tremor on the basis of spectral analysis of neuronal firing patterns

Lenz, F., Tasker, R. R., Kwan, H. C., Schider, S., Kwong, R., Dostrovsky, J. O. & Murphy, J. T., 1987, In : Applied Neurophysiology. 50, 1-6, p. 338-343 6 p.

Research output: Contribution to journalArticle

Tremor
Septal Nuclei
Neurons

Thalamic microelectrode recording and microstimulation in central and deafferentation pain

Tasker, R. R., Gorecki, J., Lenz, F., Hirayama, T. & Dostrovsky, J. O., 1987, In : Applied Neurophysiology. 50, 1-6, p. 414-417 4 p.

Research output: Contribution to journalArticle

Microelectrodes
Pain
Referred Pain
Hyperalgesia
Human Body

The role of feedback in the tremor frequency activity of tremor cells in the ventral nuclear group of human thalamus.

Lenz, F., Schnider, S., Tasker, R. R., Kwong, R., Kwan, H., Dostrovsky, J. O. & Murphy, J. T., 1987, In : Acta Neurochirurgica, Supplement. 39, p. 54-56 3 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Thalamus
1986

DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS.

Schnider, S. M., Kwong, R. H., Kwan, H. C. & Lenz, F., 1986, Proceedings of the IEEE Conference on Decision and Control. IEEE, p. 291-294 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neurology
Closed loop systems
Feedback
Identification (control systems)
1985

Cross-correlation analysis of thalamic neurons and EMG activity in parkinsonian tremor

Lenz, F., Tasker, R. R., Kwan, H. C., Schnider, S., Kwong, R. & Murphy, J. T., 1985, In : Stereotactic and Functional Neurosurgery. 48, 1-6, p. 305-308 4 p.

Research output: Contribution to journalArticle

Tremor
Neurons
Population
1983

Electromyographic response to displacement of different forelimb joints in the squirrel monkey

Lenz, F., Tatton, W. G. & Tasker, R. R., 1983, In : Journal of Neuroscience. 3, 4, p. 783-794 12 p.

Research output: Contribution to journalArticle

Saimiri
Forelimb
Joints
Muscles
Tendons

The effect of cortical lesions on the electromyographic response to joint displacement in the squirrel monkey forelimb

Lenz, F., Tatton, W. G. & Tasker, R. R., 1983, In : Journal of Neuroscience. 3, 4, p. 795-805 11 p.

Research output: Contribution to journalArticle

Saimiri
Forelimb
Motor Cortex
Joints
Torque
1976

Effect of acetylene structure on the rates and products of addition of 4-chlorobenzenesulfenyl chloride

Schmid, G. H., Modro, A., Lenz, F., Garratt, D. G. & Yates, K., 1976, In : Journal of Organic Chemistry. 41, 13, p. 2331-2336 6 p.

Research output: Contribution to journalArticle

Acetylene
Alkynes
Chlorides
Ions
Derivatives