Frederick Lenz

Professor

1976 …2020
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Research Output 1976 2020

Article

Pain encoding in the human forebrain: Binary and analog exteroceptive channels

Lenz, F., Ohara, S., Gracely, R. H., Dougherty, P. M. & Patel, S. H., Jul 21 2004, In : Journal of Neuroscience. 24, 29, p. 6540-6544 5 p.

Research output: Contribution to journalArticle

Prosencephalon
Spinothalamic Tracts
Pain
Brain
Emotions

Painful cutaneous laser stimuli induce event-related gamma-band activity in the lateral thalamus of humans

Kim, J. H., Chien, J. H., Liu, C. C. & Lenz, F., 2015, In : Journal of Neurophysiology. 113, 5, p. 1564-1573 10 p.

Research output: Contribution to journalArticle

Thalamus
Lasers
Skin
Pain
Electroencephalography

Painful cutaneous laser stimuli induce event-related oscillatory EEG activities that are different from those induced by nonpainful electrical stimuli

Chien, J. H., Liu, C. C., Kim, J. H., Markman, T. M. & Lenz, F., Aug 15 2014, In : Journal of Neurophysiology. 112, 4, p. 824-833 10 p.

Research output: Contribution to journalArticle

Electroencephalography
Lasers
Skin
Linear Models
Pain

Painful laser stimuli induce directed functional interactions within and between the human amygdala and hippocampus

Liu, C. C., Shi, C. Q., Franaszczuk, P. J., Crone, N. E., Schretlen, D., Ohara, S. & Lenz, F., Mar 31 2011, In : Neuroscience. 178, p. 208-217 10 p.

Research output: Contribution to journalArticle

Amygdala
Hippocampus
Lasers
Implanted Electrodes
Temporal Lobe Epilepsy

Painful stimuli evoke potentials recorded from the medial temporal lobe in humans

Liu, C. C., Ohara, S., Franaszczuk, P., Zagzoog, N., Gallagher, M. & Lenz, F., Feb 17 2010, In : Neuroscience. 165, 4, p. 1402-1411 10 p.

Research output: Contribution to journalArticle

Temporal Lobe
Nociceptors
Implanted Electrodes
Amygdala
Fear

Painful stimuli evoke potentials recorded from the parasylvian cortex in humans

Lenz, F., Rios, M., Chau, D., Krauss, G., Zirh, T. A. & Lesser, R. P., Oct 1998, In : Journal of Neurophysiology. 80, 4, p. 2077-2088 12 p.

Research output: Contribution to journalArticle

Scalp
Hand
Evoked Potentials
Implanted Electrodes
Gas Lasers

Painful stimuli evoke potentials recorded over the human anterior cingulate gyrus

Lenz, F., Rios, Zirh, Chau, Krauss, G. & Lesser, R. P., 1998, In : Journal of Neurophysiology. 79, 4, p. 2231-2234 4 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Gas Lasers
Motor Cortex
Prefrontal Cortex
Scalp

Pain-related evoked potentials from parasylvian cortex in humans.

Treede, R. D., Vogel, H., Rios, M., Krauss, G., Lesser, R. P. & Lenz, F., 1999, In : Electroencephalography and clinical neurophysiology. Supplement. 49, p. 250-254 5 p.

Research output: Contribution to journalArticle

Somatosensory Cortex
Somatosensory Evoked Potentials
Evoked Potentials
Pain

Pain sensitivity alterations as a function of lesion location in the parasylvian cortex

Greenspan, J. D., Lee, R. R. & Lenz, F., Jun 1 1999, In : Pain. 81, 3, p. 273-282 10 p.

Research output: Contribution to journalArticle

Pain Threshold
Pain
Cerebral Cortex
Hand
Hot Temperature

Pallidal activity during dystonia: Somatosensory reorganisation and changes with severity

Lenz, F., Suarez, J., Metman, L. V., Reich, S. G., Karp, B. I., Hallett, M., Rowland, L. H. & Dougherty, P. M., 1998, In : Journal of Neurology Neurosurgery and Psychiatry. 65, 5, p. 767-770 4 p.

Research output: Contribution to journalArticle

Dystonia
Globus Pallidus
Dyskinesias
Pallidotomy
Upper Extremity

Pallidotomy for hemiballismus: Efficacy and characteristics of neuronal activity

Suarez, J., Verhagen Merman, L., Reich, S. G., Dougherty, P. M., Hallett, M. & Lenz, F., Nov 1997, In : Annals of Neurology. 42, 5, p. 807-811 5 p.

Research output: Contribution to journalArticle

Pallidotomy
Dyskinesias
Globus Pallidus
Thalamus
Parkinson Disease

Passing lanes and slow lanes into the nociceptive network of the human brain

Treede, R. D. & Lenz, F., Aug 2006, In : Pain. 123, 3, p. 223-225 3 p.

Research output: Contribution to journalArticle

Neural Pathways
Nociceptors
Brain

Patterns of bursting occurring in thalamic cells during parkinsonian tremor

Zirh, T. A., Lenz, F., Reich, S. G. & Dougherty, P. M., Mar 1998, In : Neuroscience. 83, 1, p. 107-121 15 p.

Research output: Contribution to journalArticle

Tremor
Reflex
Deceleration
Thalamus
Ventral Thalamic Nuclei

Persistent neuronal firing in primary somatosensory cortex in the absence of working memory of trial-specific features of the sample stimuli in a haptic working memory task

Wang, L., Li, X., Hsiao, S. S., Bodner, M., Lenz, F. & Zhou, Y. D., Mar 2012, In : Journal of Cognitive Neuroscience. 24, 3, p. 664-676 13 p.

Research output: Contribution to journalArticle

Somatosensory Cortex
memorandum
Short-Term Memory
stimulus
Neurons

Physiological changes in primate somatosensory thalamus induced by deafferentation are dependent on the spinal funiculi that are sectioned and time following injury

Weng, H. R., Lenz, F., Vierck, C. & Dougherty, P. M., Feb 28 2003, In : Neuroscience. 116, 4, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

Thalamus
Primates
Neurons
Wounds and Injuries
Survival

Plasticity of pain-related neuronal activity in the human thalamus

Lenz, F., Lee, J. I., Garonzik, I., Rowland, L. H., Dougherty, P. M. & Hua, S. E., 2000, In : Progress in Brain Research. 129, p. 259-273 15 p.

Research output: Contribution to journalArticle

Thalamus
Human Activities
Pain

Postoperative symptoms of psychosis after deep brain stimulation in patients with Parkinson's disease

Qureshi, A. A., Cheng, J. J., Sunshine, A. N., Wu, A., Pontone, G. M., Cascella, N., Lenz, F., Grill, S. E. & Anderson, W. S., 2015, In : Neurosurgical Focus. 38, 6, E5.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Psychotic Disorders
Parkinson Disease
Incidence
Ambulatory Care

Posture-related oscillations in human cerebellar thalamus in essential tremor are enabled by voluntary motor circuits

Hua, S. E. & Lenz, F., Jan 2005, In : Journal of Neurophysiology. 93, 1, p. 117-127 11 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Posture
Thalamus
Neurons

Prefrontal cortex and somatosensory cortex in tactile crossmodal association: An independent component analysis of ERP recordings

Ku, Y., Ohara, S., Wang, L., Lenz, F., Hsiao, S. S., Bodner, M., Hong, B. & Zhou, Y. D., Aug 22 2007, In : PLoS One. 2, 8, e771.

Research output: Contribution to journalArticle

Neurophysiology
Somatosensory Cortex
Independent component analysis
Touch
Prefrontal Cortex

'Pseudo-neglect' in CRPS is closer to 'anti-neglect' than to classical hemi-neglect?

Greenspan, J. D., Treede, R. D. & Lenz, F., Nov 2012, In : Pain. 153, 11, p. 2157-2158 2 p.

Research output: Contribution to journalArticle

Space Perception
Perceptual Disorders
Reflex Sympathetic Dystrophy
Body Image

Psychophysical elements of place and modality specificity in the thalamic somatic sensory nucleus (ventral caudal, Vc) of awake humans

Patel, S., Ohara, S., Dougherty, P. M., Gracely, R. H. & Lenz, F., Feb 2006, In : Journal of Neurophysiology. 95, 2, p. 646-659 14 p.

Research output: Contribution to journalArticle

Thalamus
Human Body
Movement Disorders
Haplorhini

Psychophysics of CNS pain-related activity: Binary and analog channels and memory encoding

Bagley, C. A., Ohara, S., Lawson, H. C. & Lenz, F., Feb 2006, In : Neuroscientist. 12, 1, p. 29-42 14 p.

Research output: Contribution to journalArticle

Psychophysics
Spinothalamic Tracts
Pain
Afferent Pathways
Prosencephalon

Quantitative somatic sensory testing and functional imaging of the response to painful stimuli before and after cingulotomy for obsessive-compulsive disorder (OCD)

Greenspan, J. D., Coghill, R. C., Gilron, I., Sarlani, E., Veldhuijzen, D. S. & Lenz, F., Nov 2008, In : European Journal of Pain (United Kingdom). 12, 8, p. 990-999 10 p.

Research output: Contribution to journalArticle

Obsessive-Compulsive Disorder
Gyrus Cinguli
Acute Pain
Pain
Hot Temperature

Recordings of abnormal activity in patients with deafferentation and central pain

Hirayama, T., Dostrovsky, J. O., Gorecki, J., Tasker, R. R. & Lenz, F., 1989, In : Stereotactic and Functional Neurosurgery. 52, 2-4, p. 120-126 7 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Pain

Reliability of early cortical auditory gamma-band responses

Cervenka, M., Franaszczuk, P. J., Crone, N. E., Hong, B., Caffo, B. S., Bhatt, P., Lenz, F. & Boatman-Reich, D., Jan 2013, In : Clinical Neurophysiology. 124, 1, p. 70-82 13 p.

Research output: Contribution to journalArticle

Reproducibility of Results
Matched-Pair Analysis
Auditory Evoked Potentials
Noise
Epilepsy
Dystonia
Skin
Essential Tremor
Human Body
Thalamus

Reorganization of sensory modalities evoked by microstimulation in region of the thalamic principal sensory nucleus in patients with pain due to nervous system injury

Lenz, F., Gracely, R. H., Baker, F. H., Richardson, R. T. & Dougherty, P. M., Sep 14 1998, In : Journal of Comparative Neurology. 399, 1, p. 125-138 14 p.

Research output: Contribution to journalArticle

Nervous System Trauma
Pain
Chronic Pain
Hot Temperature
Movement Disorders

Reorganization of somatic sensory function in the human thalamus after stroke

Ohara, S. & Lenz, F., 2001, In : Annals of Neurology. 50, 6, p. 800-803 4 p.

Research output: Contribution to journalArticle

Thalamus
Stroke
Anterior Thalamic Nuclei
Essential Tremor
Microelectrodes

Reply

Klein, M. M., Treister, R., Raij, T., Pascual-Leone, A., Park, L., Nurmikko, T., Lenz, F., Lefaucheur, J. P., Lang, M., Hallett, M., Fox, M., Costello, A., Carr, D. B., Ayache, S. S. & Oaklander, A. L., May 1 2016, In : Pain. 157, 5, p. 1175-1176 2 p.

Research output: Contribution to journalArticle

Pain Management
Biomedical Research
Pain
Brain
Transcranial Direct Current Stimulation

Responses of neurons in the region of human thalamic principal somatic sensory nucleus to mechanical and thermal stimuli graded into the painful range

Lee, J. I., Dougherty, P. M., Antezana, D. & Lenz, F., Aug 9 1999, In : Journal of Comparative Neurology. 410, 4, p. 541-555 15 p.

Research output: Contribution to journalArticle

Hot Temperature
Neurons
Ventral Thalamic Nuclei
Movement Disorders
Skin

Responses of primate spinomesencephalic tract cells to intradermal capsaicin

Dougherty, P. M., Schwartz, A. & Lenz, F., Jun 1999, In : Neuroscience. 90, 4, p. 1377-1392 16 p.

Research output: Contribution to journalArticle

Capsaicin
Primates
Periaqueductal Gray
Excitatory Amino Acids
Injections

Reversal of postischemic hypoperfusion by tempol: Endothelial signal transduction mechanism

Okada, T., Teranishi, K., Chen, Y., Tomori, T., Strasser, A., Lenz, F., McCarron, R. M. & Spatz, M., Apr 2012, In : Neurochemical Research. 37, 4, p. 680-688 9 p.

Research output: Contribution to journalArticle

Reactive Nitrogen Species
Signal transduction
Reactive Oxygen Species
Signal Transduction
Inositol 1,4,5-trisphosphate 3-kinase

Review of motor and phantom-related imagery

Anderson, W. S. & Lenz, F., Dec 7 2011, In : NeuroReport. 22, 17, p. 939-942 4 p.

Research output: Contribution to journalArticle

Imagery (Psychotherapy)
Amputees
Parietal Lobe
Brain
Neuroimaging

Right Hemisphere Language Dominance in a Right-Handed Patient with Late-Onset Seizures

Boatman, D. F., Alidoost, M., Bergey, G. K., Gordon, B., Crone, N. E., Hart, J. & Lenz, F., Aug 2000, In : Epilepsy and Behavior. 1, 4, p. 281-286 6 p.

Research output: Contribution to journalArticle

Patient Rights
Seizures
Language
Speech-Language Pathology
Amobarbital

Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models

Lenz, F., Vitek, J. L. & DeLong, M. R., 1993, In : Stereotactic and Functional Neurosurgery. 60, 1-3, p. 94-103 10 p.

Research output: Contribution to journalArticle

Tremor
Thalamus
Primates
Basal Ganglia
Haplorhini

Scientific position paper of the movement disorder society evaluation of surgery for Parkinson's disease

Hallett, M., Litvan, I., Lenz, F., Ahlskog, E., Grossman, R., Jankovic, J., Narabayashi, H., Tasker, R., Lozano, A. M., Delong, M., Lang, A. E., Obeso, J. A., Waters, C., Koller, W. C., Benabid, A. L., Caparros-Lefebvre, D., Nutt, J. G., Pollak, P., Siegfried, J., Goetz, C. & 2 others, Defer, G. L. & Lopez-Lozano, J. J., 2000, In : Movement disorders : official journal of the Movement Disorder Society. 15, 3, p. 436-438 3 p.

Research output: Contribution to journalArticle

Brain Tissue Transplantation
Outcome and Process Assessment (Health Care)
Fetal Tissue Transplantation
Stereotaxic Techniques
Cerebral Dominance

Selection of the optimal lesion site for the relief of parkinsonian tremor on the basis of spectral analysis of neuronal firing patterns

Lenz, F., Tasker, R. R., Kwan, H. C., Schider, S., Kwong, R., Dostrovsky, J. O. & Murphy, J. T., 1987, In : Applied Neurophysiology. 50, 1-6, p. 338-343 6 p.

Research output: Contribution to journalArticle

Tremor
Septal Nuclei
Neurons
Torticollis
Superficial Back Muscles
Denervation
Muscles
Therapeutics

Sequential neural processes of tactile-visual crossmodal working memory

Ohara, S., Lenz, F. & Zhou, Y. D., 2006, In : Neuroscience. 139, 1, p. 299-309 11 p.

Research output: Contribution to journalArticle

Touch
Short-Term Memory
Evoked Potentials
Scalp
Cognition

Single-neuron analysis of human thalamus in patients with intention tremor and other clinical signs of cerebellar disease

Lenz, F., Jaeger, C. J., Seike, M. S., Lin, Y. C. & Reich, S. G., 2002, In : Journal of Neurophysiology. 87, 4, p. 2084-2094 11 p.

Research output: Contribution to journalArticle

Cerebellar Diseases
Tremor
Thalamus
Neurons
Cerebellar Nuclei

Single unit analysis of the human ventral thalamic nuclear group: Activity correlated with movement

Lenz, F., Kwan, H. C., Dostrovsky, J. O., Tasker, R. R., Murphy, J. T. & Lenz, Y. E., Dec 1990, In : Brain. 113, 6, p. 1795-1821 27 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Neurons
Sensory feedback
Unit
Cell

Single unit analysis of the human ventral thalamic nuclear group: Tremor-related activity in functionally identified cells

Lenz, F., Kwan, H. C., Martin, R. L., Tasker, R. R., Dostrovsky, J. O. & Lenz, Y. E., Jun 1994, In : Brain. 117, 3, p. 531-543 13 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Cells
Unit
Cell

Single unit analysis of the human ventral thalamic nuclear group: Correlation of thalamic 'tremor cells' with the 3-6 Hz component of Parkinsonian tremor

Lenz, F., Tasker, R. R., Kwam, H. C., Schnider, S., Kwong, R., Murayama, Y., Dostrovsky, J. O. & Murphy, J. T., 1988, In : Journal of Neuroscience. 8, 3, p. 754-764 11 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Electromyography
Fingers
Signal-To-Noise Ratio

Single-unit analysis of the human ventral thalamic nuclear group: Somatosensory responses

Lenz, F., Dostrovsky, J. O., Tasker, R. R., Yamashiro, K., Kwan, H. C. & Murphy, J. T., 1988, In : Journal of Neurophysiology. 59, 2, p. 299-316 18 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Skin
Body Regions
Fingers
Elbow

Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

Muthuswamy, J., Tran, P., Rangarajan, R., Lenz, F., Hanley, D. F. & Thakor, N. V., Mar 12 1999, In : Neuroscience Letters. 262, 3, p. 191-194 4 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Thalamus
Evoked Potentials
barbituric acid

Spatial attention to thermal pain stimuli in subjects with visual spatial hemi-neglect: Extinction, mislocalization and misidentification of stimulus modality

Liu, C. C., Veldhuijzen, D. S., Ohara, S., Winberry, J., Greenspan, J. D. & Lenz, F., Mar 2011, In : Pain. 152, 3, p. 498-506 9 p.

Research output: Contribution to journalArticle

Hot Temperature
Pain
Psychological Extinction
Stroke
Control Groups

Spatial neglect during electrocortical stimulation mapping in the right hemisphere

Kleinman, J. T., Sepkuty, J. P., Hillis-Trupe, A., Lenz, F., Heidler-Gary, J., Gingis, L. & Crone, N. E., Dec 2007, In : Epilepsia. 48, 12, p. 2365-2368 4 p.

Research output: Contribution to journalArticle

Perceptual Disorders
Parietal Lobe
Temporal Lobe
Epilepsy
Electrodes

Speech recognition impairments in patients with intractable right temporal lobe epilepsy

Boatman, D. F., Lesser, R. P., Crone, N. E., Krauss, G., Lenz, F. & Miglioretti, D. L., Aug 2006, In : Epilepsia. 47, 8, p. 1397-1401 5 p.

Research output: Contribution to journalArticle

Temporal Lobe Epilepsy
Amobarbital
Partial Epilepsy
Patient Rights
Temporal Lobe

Spinal cord injury: A small step forward for spinal cord injury patients?

Anderson, W. S. & Lenz, F., Aug 2011, In : Nature Reviews Neurology. 7, 8, p. 422-423 2 p.

Research output: Contribution to journalArticle

Spinal Cord Stimulation
Spinal Cord Injuries
Cervical Cord

Spontaneous low threshold spike bursting in awake humans is different in different lateral thalamic nuclei

Ohara, S., Taghva, A., Kim, J. H. & Lenz, F., Jun 2007, In : Experimental Brain Research. 180, 2, p. 281-288 8 p.

Research output: Contribution to journalArticle

Lateral Thalamic Nuclei
Calcium Signaling
Neurons
Thalamic Diseases
Essential Tremor