Frederick Lenz

Professor

1976 …2018
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Research Output 1976 2018

Article

Statistical prediction of the optimal site for thalamotomy in parkinsonian tremor

Lenz, F., Normand, S. L., Kwan, H. C., Andrews, D., Rowland, L. H., Jones, M. W., Seike, M., Lin, Y. C., Tasker, R. R., Dostrovsky, J. O. & Lenz, Y. E., 1995, In : Movement disorders : official journal of the Movement Disorder Society. 10, 3, p. 318-328 11 p.

Research output: Contribution to journalArticle

Tremor
Neurons
Thalamus
Therapeutics

Stereotactic ablative and stimulation procedures for treatment of movement disorders

Vitek, J. L., Lozano, A. M. & Lenz, F., Jun 1999, In : Neurosurgery Quarterly. 9, 2, p. 103-119 17 p.

Research output: Contribution to journalArticle

Movement Disorders
Deep Brain Stimulation
Tremor
Pallidotomy
Parkinson Disease

Stereotactic thalamotomy in the treatment of essential tremor of the upper extremity: Reassessment including a blinded measure of outcome

Zirh, A., Reich, S. G., Dougherty, P. M. & Lenz, F., Jun 1999, In : Journal of Neurology Neurosurgery and Psychiatry. 66, 6, p. 772-775 4 p.

Research output: Contribution to journalArticle

Essential Tremor
Handwriting
Upper Extremity
Tremor
Outcome Assessment (Health Care)

Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced pain

Lenz, F., Gracely, R. H., Romanoski, A. J., Hope, E. J., Rowland, L. H. & Dougherty, P. M., 1995, In : Nature Medicine. 1, 9, p. 910-913 4 p.

Research output: Contribution to journalArticle

Thalamus
Chemical activation
Pain
Panic Disorder
Tremor

Stroke of bad luck?

Kim, E. H., Chien, J. H., Liu, C. C., Oishi, K., Oishi, K., Sebastian, R., Demsky, C., Lenz, F. & Hillis-Trupe, A., Jan 2 2017, In : Neurocase. 23, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

Stroke
Skin
Emotions
Luck
Rating
Pain
Causality
Electrodes
Therapeutics
Epilepsy

Studies of the human ascending pain pathways

Weiss, N., Lawson, H. C., Greenspan, J. D., Ohara, S. & Lenz, F., Mar 2005, In : Thalamus and Related Systems. 3, 1, p. 71-86 16 p.

Research output: Contribution to journalArticle

Chronic Pain
Primates
Pain Clinics
Pain
Nociception

Surgery insight: Deep brain stimulation for movement disorders

Anderson, W. S. & Lenz, F., Jun 2006, In : Nature Clinical Practice Neurology. 2, 6, p. 310-320 11 p.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Movement Disorders
Parkinson Disease
Essential Tremor
Tourette Syndrome

Surgery of the motor thalamus: Problems with the present nomenclatures

Krack, P., Dostrovsky, J., Ilinsky, I., Kultas-Ilinsky, K., Lenz, F., Lozano, A. & Vitek, J., 2002, In : Movement disorders : official journal of the Movement Disorder Society. 17, SUPPL. 3

Research output: Contribution to journalArticle

Thalamus
Terminology
Haplorhini
Thalamic Nuclei
Atlases

Thalamic mechanisms of chest pain in the absence of cardiac pathology.

Lenz, F., Dougherty, P. M. & Traill, T. A., May 1996, In : Heart. 75, 5, p. 429-430 2 p.

Research output: Contribution to journalArticle

Microvascular Angina
Viscera
Chest Pain
Thalamus
Abdominal Pain

Thalamic mechanisms of pain and pain modulation

Lenz, F., 1993, In : European Journal of Pain (United Kingdom). 14, 2, p. 21-24 4 p.

Research output: Contribution to journalArticle

Pain

Thalamic microelectrode recording and microstimulation in central and deafferentation pain

Tasker, R. R., Gorecki, J., Lenz, F., Hirayama, T. & Dostrovsky, J. O., 1987, In : Applied Neurophysiology. 50, 1-6, p. 414-417 4 p.

Research output: Contribution to journalArticle

Microelectrodes
Pain
Referred Pain
Hyperalgesia
Human Body

Thalamic neuronal activity correlated with essential tremor

Hua, S. E., Lenz, F., Zirh, T. A., Reich, S. G. & Dougherty, P. M., Feb 1998, In : Journal of Neurology Neurosurgery and Psychiatry. 64, 2, p. 273-276 4 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Harmaline
Thalamus
Forearm

Thalamic neuronal and EMG activity in psychogenic dystonia compared with organic dystonia

Kobayashi, K., Lang, A. E., Hallett, M. & Lenz, F., Jun 2011, In : Movement disorders : official journal of the Movement Disorder Society. 26, 7, p. 1348-1352 5 p.

Research output: Contribution to journalArticle

Dystonic Disorders
Dystonia
Electromyography
Signal-To-Noise Ratio
Ventral Thalamic Nuclei

Thalamic physiology of intentional essential tremor is more like cerebellar tremor than postural essential tremor

Zakaria, R., Lenz, F., Hua, S., Avin, B. H., Liu, C. C. & Mari, Z., Sep 5 2013, In : Brain Research. 1529, p. 188-199 12 p.

Research output: Contribution to journalArticle

Essential Tremor
Tremor
Ventral Thalamic Nuclei
Cerebellar Diseases
Cerebellar Nuclei

Thalamic post-inhibitory bursting occurs in patients with organic dystonia more often than controls

Kobayashi, K., Liu, C. C., Jensen, A. L., Vitek, J. L., Mari, Z. & Lenz, F., Dec 6 2013, In : Brain Research. 1541, p. 81-91 11 p.

Research output: Contribution to journalArticle

Dystonia
Ventral Thalamic Nuclei
Dystonic Disorders
Signal-To-Noise Ratio
Haplorhini

Thalamic single neuron activity in patients with dystonia: Dystonia- related activity and somatic sensory reorganization

Lenz, F., Jaeger, C. J., Seike, M. S., Lin, Y. C., Reich, S. G., DeLong, M. R. & Vitek, J. L., 1999, In : Journal of Neurophysiology. 82, 5, p. 2372-2392 21 p.

Research output: Contribution to journalArticle

Dystonia
Neurons
Muscles
Joints
Muscle Contraction

Thalamic single neuron and electromyographic activities in patients with dystonia.

Zirh, T. A., Reich, S. G., Perry, V. & Lenz, F., 1998, In : Advances in neurology. 78, p. 27-32 6 p.

Research output: Contribution to journalArticle

Somatosensory Evoked Potentials
Dystonia
Microelectrodes
Electromyography
Thalamus

Thalamic single-unit activity occurring in patients with hemidystonia

Lenz, F., Martin, R., Kwan, H. C., Tasker, R. R. & Dostrovsky, J. O., 1990, In : Stereotactic and Functional Neurosurgery. 54, 1-8, p. 159-162 4 p.

Research output: Contribution to journalArticle

Dystonia
Dyskinesias
Thalamus
Upper Extremity

Thalamic stimulation and recording in patients with deafferentation and central pain

Gorecki, J., Hirayama, T., Dostrovsky, J. O., Tasker, R. R. & Lenz, F., 1989, In : Stereotactic and Functional Neurosurgery. 52, 2-4, p. 219-226 8 p.

Research output: Contribution to journalArticle

Hyperalgesia
Microelectrodes
Thalamus
Pain

The effect of cortical lesions on the electromyographic response to joint displacement in the squirrel monkey forelimb

Lenz, F., Tatton, W. G. & Tasker, R. R., 1983, In : Journal of Neuroscience. 3, 4, p. 795-805 11 p.

Research output: Contribution to journalArticle

Saimiri
Forelimb
Motor Cortex
Joints
Torque

The human thalamic somatic sensory nucleus [Ventral caudal (Vc)] shows neuronal mechanoreceptor-like responses to optimal stimuli for peripheral mechanoreceptors

Weiss, N., Ohara, S., Johnson, K. O. & Lenz, F., Feb 2009, In : Journal of Neurophysiology. 101, 2, p. 1033-1042 10 p.

Research output: Contribution to journalArticle

Mechanoreceptors
Pacinian Corpuscles
Neurons
Vibration
Skin

Thermal and pain sensations evoked by microstimulation in the area of human ventrocaudal nucleus

Lenz, F., Seike, M., Richardson, R. T., Lin, Y. C., Baker, F. H., Khoja, I., Jaeger, C. J. & Gracely, R. H., 1993, In : Journal of Neurophysiology. 70, 1, p. 200-210 11 p.

Research output: Contribution to journalArticle

Hot Temperature
Pain
Skin
Referred Pain
Metatarsophalangeal Joint

The role of feedback in the tremor frequency activity of tremor cells in the ventral nuclear group of human thalamus.

Lenz, F., Schnider, S., Tasker, R. R., Kwong, R., Kwan, H., Dostrovsky, J. O. & Murphy, J. T., 1987, In : Acta Neurochirurgica, Supplement. 39, p. 54-56 3 p.

Research output: Contribution to journalArticle

Ventral Thalamic Nuclei
Tremor
Thalamus

The role of the thalamus and basal ganglia in parkinsonian tremor

Hua, S., Reich, S. G., Zirh, A. T., Perry, V., Dougherty, P. M. & Lenz, F., 1998, In : Movement disorders : official journal of the Movement Disorder Society. 13, SUPPL. 3, p. 40-42 3 p.

Research output: Contribution to journalArticle

Tremor
Basal Ganglia
Thalamus
Sensory Feedback
Globus Pallidus

The sensation of angina can be evoked by stimulation of the human thalamus

Lenz, F., Gracely, R. H., Hope, E. J., Baker, F. H., Rowland, L. H., Dougherty, P. M. & Richardson, R. T., 1994, In : Pain. 59, 1, p. 119-125 7 p.

Research output: Contribution to journalArticle

Thalamus
Arachnoiditis
Unstable Angina
Wounds and Injuries
Thoracic Wall

The sensory-limbic model of pain memory: Connections from thalamus to the limbic system mediate the learned component of the affective dimension of pain

Casey, K. L., Ledoux, J., Gabriel, M., Lenz, F., Gracely, R. H., Zirh, A. T., Romanoski, A. J., Staats, P. & Dougherty, P. M., 1997, In : Pain Forum. 6, 1, p. 22-43 22 p.

Research output: Contribution to journalArticle

Limbic System
Thalamus
Pain
Somatosensory Cortex
Cerebral Cortex

The ventral posterior nucleus of thalamus is involved in the generation of central pain syndromes

Lenz, F., 1992, In : APS Journal. 1, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

Posterior Thalamic Nuclei
Ventral Thalamic Nuclei
Pain
Excitatory Amino Acids
Calcium

Transcortical sensory aphasia: Revisited and revised

Boatman, D. F., Gordon, B., Hart, J., Selnes, O., Miglioretti, D. & Lenz, F., Aug 2000, In : Brain. 123, 8, p. 1634-1642 9 p.

Research output: Contribution to journalArticle

Wernicke Aphasia
Language
Amobarbital
Phonetics
Semantics

Transcranial magnetic stimulation of the brain: Guidelines for pain treatment research

Klein, M. M., Treister, R., Raij, T., Pascual-Leone, A., Park, L., Nurmikko, T., Lenz, F., Lefaucheur, J. P., Lang, M., Hallett, M., Fox, M., Cudkowicz, M., Costello, A., Carr, D. B., Ayache, S. S. & Oaklander, A. L., Sep 1 2015, In : Pain. 156, 9, p. 1601-1614 14 p.

Research output: Contribution to journalArticle

Transcranial Magnetic Stimulation
Guidelines
Pain
Brain
Research

Transient inhibition of responses to thermal stimuli of spinal sensory tract neurons in monkeys during sensitization by intradermal capsaicin

Dougherty, P. M., Willis, W. D. & Lenz, F., Aug 1998, In : Pain. 77, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

Capsaicin
Sensory Receptor Cells
Haplorhini
Hyperalgesia
Hot Temperature

Transient unilateral hearing loss induced by electrocortical stimulation

Sinha, S. R., Crone, N. E., Fotta, R., Lenz, F. & Boatman, D. F., Jan 25 2005, In : Neurology. 64, 2, p. 383-385 3 p.

Research output: Contribution to journalArticle

Unilateral Hearing Loss
Temporal Lobe
Hearing
Ear
Seizures

Tremor-frequency (3-6 Hz) activity in the sensorimotor arm representation of the internal segment of the globus pallidus in patients with Parkinson's disease

Lemstra, A. W., Verhagen Metman, L., Lee, J. I., Dougherty, P. M. & Lenz, F., May 28 1999, In : Neuroscience Letters. 267, 2, p. 129-132 4 p.

Research output: Contribution to journalArticle

Globus Pallidus
Tremor
Parkinson Disease
Arm
Neurons
Book

The human pain system: Experimental and clinical perspectives

Lenz, F., Casey, K. L., Jones, E. G. & Willis, W. D., Oct 1 2010, Cambridge University Press. 638 p.

Research output: Book/ReportBook

Pain
Primates
Rodentia
Anatomy
Pharmacology
Chapter

Chapter 59 Neurosurgical treatment of pain

Lenz, F., 2006, Handbook of Clinical Neurology. Vol. 81. p. 869-885 17 p. (Handbook of Clinical Neurology; vol. 81).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pain
Therapeutics

Controversies in the mechanism of central pain

Chien, J. H., Kim, J. H., Cheng, J. J., Liu, C. C., Greenspan, J. D. & Lenz, F. A., May 28 2015, The Brain Adapting with Pain: Contribution of Neuroimaging Technology to Pain Mechanisms. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Pain

Endogenous and exogenous modulators of potentials evoked by a painful cutaneous laser (LEPs)

Ohara, S., Anderson, W. S., Lawson, H. C., Lee, H. T. & Lenz, F., Jan 1 2006, Advances in Functional and Reparative Neurosurgery. 99 ed. Springer-Verlag Wien, p. 77-79 3 p. (Acta Neurochirurgica, Supplementum; no. 99).

Research output: Chapter in Book/Report/Conference proceedingChapter

Evoked Potentials
Lasers
Pain
Skin
Gyrus Cinguli

Neck pain

Bagley, C. A., Garonzik, I. & Lenz, F., Mar 27 2012, Principles of Ambulatory Medicine: Seventh Edition. Wolters Kluwer Health, p. 1157-1165 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neck Pain

Neurological Indications for Deep Brain Stimulation

Cheng, J. J., Anderson, W. S. & Lenz, F., Jun 5 2015, Brain Stimulation: Methodologies and Interventions. wiley, p. 271-287 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Deep Brain Stimulation
Parkinson Disease
Essential Tremor
Tourette Syndrome
Subthalamic Nucleus

Neurosurgical treatment of cancer pain

Hurley, R. W. & Lenz, F., Jan 1 2009, Cancer Pain: Assessment and Management, Second Edition. Cambridge University Press, p. 329-340 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pain
Opiate Alkaloids
Therapeutics
Nervous System Trauma
Nociceptive Pain

Psychophysics of Sensations Evoked by Stimulation of the Human Central Nervous System

Ohara, S., Bagley, C. A., Lawson, H. C. & Lenz, F., 2010, The Senses: A Comprehensive Reference. Elsevier Inc., Vol. 5. p. 655-668 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Psychophysics
Central Nervous System
Pain
Prosencephalon
Spinothalamic Tracts

Thalamic Burst Firing in Response to Experimental Pain Stimuli and in Patients with Chronic Neuropathic Pain may be a Carrier for Pain-Related Signals

Markman, T. M., Liu, C. C., Zhang, J. C., Kobayashi, K., Kim, J. H. & Lenz, F. A., Aug 2013, Chronic Pain and Brain Abnormalities. Elsevier Inc., p. 41-60 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuralgia
Chronic Pain
Lasers
Pain
Thalamus

Thalamotomy

von Coelln, R., Kobayashi, K., Kim, J. H., Anderson, W. S., Winberry, J. & Lenz, F. A., Jan 1 2010, Encyclopedia of Movement Disorders. Elsevier Inc., p. 226-229 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tremor
Ventral Thalamic Nuclei
Essential Tremor
Deep Brain Stimulation
Microelectrodes

The Thalamus

Chien, J. H., Cheng, J. J. & Lenz, F., Oct 11 2016, Conn's Translational Neuroscience. Elsevier Inc., p. 289-297 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Thalamus
Thalamic Nuclei
Wakefulness
Sleep Stages
Electrophysiology

What can neuroimaging tell us about central pain?

Veldhuijzen, D. S., Lenz, F., Lagraize, S. C. & Greenspan, J. D., Jan 1 2009, Translational Pain Research: From Mouse to Man. CRC Press, p. 315-328 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuroimaging
Neurology
Pain
Central Nervous System
Conference contribution

DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS.

Schnider, S. M., Kwong, R. H., Kwan, H. C. & Lenz, F., 1986, Proceedings of the IEEE Conference on Decision and Control. IEEE, p. 291-294 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neurology
Closed loop systems
Feedback
Identification (control systems)
Review article
Ventral Thalamic Nuclei
pain
Touch
loci
stimulation

Knowledge gaps and research recommendations for essential tremor

Hopfner, F., Haubenberger, D., Galpern, W. R., Gwinn, K., Van't Veer, A., White, S., Bhatia, K., Adler, C. H., Eidelberg, D., Ondo, W., Stebbins, G. T., Tanner, C. M., Helmich, R. C., Lenz, F., Sillitoe, R. V., Vaillancourt, D., Vitek, J. L., Louis, E. D., Shill, H. A., Frosch, M. P. & 7 others, Foroud, T., Kuhlenbäumer, G., Singleton, A., Testa, C. M., Hallett, M., Elble, R. & Deuschl, G., Dec 1 2016, In : Parkinsonism and Related Disorders. 33, p. 27-35 9 p.

Research output: Contribution to journalReview article

Essential Tremor
Research
National Institute of Neurological Disorders and Stroke
Exome
Phenotype

Neuronal responses to tactile stimuli and tactile sensations evoked by microstimulation in the human thalamic principal somatic sensory nucleus (ventral caudal)

Schmid, A. C., Chien, J. H., Greenspan, J. D., Garonzik, I., Weiss, N., Ohara, S. & Lenz, F., May 1 2016, In : Journal of Neurophysiology. 115, 5, p. 2421-2433 13 p.

Research output: Contribution to journalReview article

Touch
Essential Tremor
Dystonia
Nervous System Trauma
Neurons