Felipe A Andrade

Associate Professor

1994 …2020

Research output per year

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Research Output

2020

Citrulline Not a Major Determinant in the Recognition of Peptidylarginine Deiminase 2 and 4 by Autoantibodies in Rheumatoid Arthritis

Darrah, E., Davis, R. L., Curran, A. M., Naik, P., Chen, R., Na, C. H., Giles, J. T. & Andrade, F., 2020, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

2019

Individuals at risk of seropositive rheumatoid arthritis: the evolving story

Rantapää Dahlqvist, S. & Andrade, F., Dec 1 2019, In : Journal of Internal Medicine. 286, 6, p. 627-643 17 p.

Research output: Contribution to journalReview article

Open Access

Insights into the study and origin of the citrullinome in rheumatoid arthritis

Fert-Bober, J., Darrah, E. & Andrade, F., Jan 1 2019, (Accepted/In press) In : Immunological reviews.

Research output: Contribution to journalReview article

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

Boeltz, S., Amini, P., Anders, H. J., Andrade, F., Bilyy, R., Chatfield, S., Cichon, I., Clancy, D. M., Desai, J., Dumych, T., Dwivedi, N., Gordon, R. A., Hahn, J., Hidalgo, A., Hoffmann, M. H., Kaplan, M. J., Knight, J. S., Kolaczkowska, E., Kubes, P., Leppkes, M. & 29 others, Manfredi, A. A., Martin, S. J., Maueröder, C., Maugeri, N., Mitroulis, I., Munoz, L. E., Nakazawa, D., Neeli, I., Nizet, V., Pieterse, E., Radic, M. Z., Reinwald, C., Ritis, K., Rovere-Querini, P., Santocki, M., Schauer, C., Schett, G., Shlomchik, M. J., Simon, H. U., Skendros, P., Stojkov, D., Vandenabeele, P., Berghe, T. V., van der Vlag, J., Vitkov, L., von Köckritz-Blickwede, M., Yousefi, S., Zarbock, A. & Herrmann, M., Mar 1 2019, In : Cell death and differentiation. 26, 3, p. 395-408 14 p.

Research output: Contribution to journalReview article

2018

Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis

Shi, J., Darrah, E., Sims, G. P., Mustelin, T., Sampson, K., Konig, M. F., Bingham, C., Rosen, A. & Andrade, F. A., Jan 1 2018, In : Annals of the Rheumatic Diseases. 77, 1, p. 141-148 8 p.

Research output: Contribution to journalArticle

Autoantibodies to peptidylarginine deiminase 2 are associated with less severe disease in rheumatoid arthritis

Darrah, E., Giles, J. T., Davis, R. L., Naik, P., Wang, H., Konig, M. F., Cappelli, L. C., Bingham, C. O., Danoff, S. K. & Andrade, F., Nov 20 2018, In : Frontiers in immunology. 9, NOV, 2696.

Research output: Contribution to journalArticle

Response to comment on “Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis”

Konig, M. F., Giles, J. T., Teles, R. P., Moutsopoulos, N. M. & Andrade, F. A., Mar 21 2018, In : Science Translational Medicine. 10, 433, 3031.

Research output: Contribution to journalArticle

Rheumatoid arthritis and citrullination

Darrah, E. & Andrade, F. A., Jan 1 2018, In : Current Opinion in Rheumatology. 30, 1, p. 72-78 7 p.

Research output: Contribution to journalReview article

Rheumatoid arthritis-associated autoimmunity due to Aggregatibacter actinomycetemcomitans and its resolution with antibiotic therapy

Mukherjee, A., Jantsch, V., Khan, R., Hartung, W., Fischer, R., Jantsch, J., Ehrenstein, B., Konig, M. F. & Andrade, F., Oct 16 2018, In : Frontiers in immunology. 9, OCT, 2352.

Research output: Contribution to journalArticle

2017

Spontaneous secretion of the citrullination enzyme PAD2 and cell surface exposure of PAD4 by neutrophils

Zhou, Y., Chen, B., Mittereder, N., Chaerkady, R., Strain, M., An, L. L., Rahman, S., Ma, W., Low, C. P., Chan, D., Neal, F., Bingham, C. O., Sampson, K., Darrah, E., Siegel, R. M., Hasni, S., Andrade, F., Vousden, K. A., Mustelin, T. & Sims, G. P., Sep 25 2017, In : Frontiers in immunology. 8, SEP, 1200.

Research output: Contribution to journalArticle

2016

Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

Konig, M. F., Abusleme, L., Reinholdt, J., Palmer, R. J., Teles, R. P., Sampson, K., Rosen, A., Nigrovic, P. A., Sokolove, J., Giles, J. T., Moutsopoulos, N. M. & Andrade, F. A., Dec 14 2016, In : Science Translational Medicine. 8, 369, 369ra176.

Research output: Contribution to journalArticle

Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis

Konig, M. F., Giles, J. T., Nigrovic, P. A. & Andrade, F., Nov 1 2016, In : Annals of the rheumatic diseases. 75, 11, p. 2022-2028 7 p.

Research output: Contribution to journalArticle

2015

Citrullination of myofilament proteins in heart failure

Fert-Bober, J., Giles, J. T., Holewinski, R. J., Kirk, J. A., Uhrigshardt, H., Crowgey, E. L., Andrade, F., Bingham, C. O., Park, J. K., Halushka, M. K., Kass, D. A., Bathon, J. M. & Van Eyk, J. E., Jan 7 2015, In : Cardiovascular research. 108, 2, p. 232-242 11 p.

Research output: Contribution to journalArticle

Defining the role of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in rheumatoid arthritis through the study of PPAD biology

Konig, M. F., Paracha, A. S., Moni, M., Bingham, C. O. & Andrade, F., Nov 1 2015, In : Annals of the rheumatic diseases. 74, 11, p. 2054-2061 8 p.

Research output: Contribution to journalArticle

Development of autoantibodies against musclespecific FHL1 in severe inflammatory myopathies

Albrecht, I., Wick, C., Hallgren, A., Tjärnlund, A., Nagaraju, K., Andrade, F., Thompson, K., Coley, W., Phadke, A., Diaz-Gallo, L. M., Bottai, M., Nennesmo, I., Chemin, K., Herrath, J., Johansson, K., Wikberg, A., Jimmy Ytterberg, A., Zubarev, R. A., Danielsson, O., Krystufkova, O. & 6 others, Vencovsky, J., Landegren, N., Wahren-Herlenius, M., Padyukov, L., Kämpe, O. & Lundberg, I. E., Dec 2015, In : Journal of Clinical Investigation. 125, 12, p. 4612-4624 13 p.

Research output: Contribution to journalArticle

2014

Association of cross-reactive antibodies targeting peptidyl-arginine deiminase 3 and 4 with rheumatoid arthritis-associated interstitial lung disease

Giles, J. T., Darrah, E., Danoff, S., Johnson, C., Andrade, F., Rosen, A. & Bathon, J. M., Jun 5 2014, In : PloS one. 9, 6, e98794.

Research output: Contribution to journalArticle

2013

Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity

Darrah, E., Giles, J. T., Ols, M. L., Bull, H. G., Andrade, F. & Rosen, A., May 22 2013, In : Science translational medicine. 5, 186, 186ra65.

Research output: Contribution to journalArticle

Granzyme H

Andrade, F. & Jenne, D. E., Aug 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, Vol. 3. p. 2721-2724 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis

Romero, V., Fert-Bober, J., Nigrovic, P. A., Darrah, E., Haque, U. J., Lee, D. M., Van Eyk, J., Rosen, A. & Andrade, F., Oct 30 2013, In : Science translational medicine. 5, 209, 209ra150.

Research output: Contribution to journalArticle

2012

Myocardial citrullination in rheumatoid arthritis: A correlative histopathologic study

Giles, J. T., Fert-Bober, J., Park, J. K., Bingham, C. O., Andrade, F., Fox-Talbot, K., Pappas, D., Rosen, A., van Eyk, J., Bathon, J. M. & Halushka, M. K., Feb 24 2012, In : Arthritis Research and Therapy. 14, 1, R39.

Research output: Contribution to journalArticle

Nets: The missing link between cell death and systemic autoimmune diseases?

Darrah, E. & Andrade, F., Dec 1 2012, In : Frontiers in immunology. 3, JAN, Article 428.

Research output: Contribution to journalArticle

2011

Abnormal production of pro- and anti-inflammatory cytokines by lupus monocytes in response to apoptotic cells

Sule, S., Rosen, A., Petri, M., Akhter, E. & Andrade, F., Mar 21 2011, In : PloS one. 6, 3, e17495.

Research output: Contribution to journalArticle

2010

Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation

Andrade, F., Darrah, E., Gucek, M., Cole, R. N., Rosen, A. & Zhu, X., Jun 1 2010, In : Arthritis and rheumatism. 62, 6, p. 1630-1640 11 p.

Research output: Contribution to journalArticle

Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state

Andrade, F., May 1 2010, In : Immunological reviews. 235, 1, p. 128-146 19 p.

Research output: Contribution to journalReview article

Transcription of proteinase 3 and related myelopoiesis genes in peripheral blood mononuclear cells of patients with active Wegener's granulomatosis

Cheadle, C., Berger, A. E., Andrade, F., James, R., Johnson, K., Watkins, T., Park, J. K., Chen, Y. C., Ehrlich, E., Mullins, M., Chrest, F., Barnes, K. C. & Levine, S. M., Jun 1 2010, In : Arthritis and rheumatism. 62, 6, p. 1744-1754 11 p.

Research output: Contribution to journalArticle

2009

Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity

Romero, V., Fellows, E., Jenne, D. E. & Andrade, F., Jan 1 2009, In : Cell death and differentiation. 16, 2, p. 340-348 9 p.

Research output: Contribution to journalArticle

2008

Non-apoptotic functions of granzymes

Romero, V. & Andrade, F., May 1 2008, In : Tissue Antigens. 71, 5, p. 409-416 8 p.

Research output: Contribution to journalReview article

2007

Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition

Andrade, F., Fellows, E., Jenne, D. E., Rosen, A. & Young, C. S. H., Apr 18 2007, In : EMBO Journal. 26, 8, p. 2148-2157 10 p.

Research output: Contribution to journalArticle

2005

Apoptosis in lupus erythematosus

Andrade, F., Rosen, A. & Casciola-Rosen, L., Dec 1 2005, Cutaneous Lupus Erythematosus. Springer Berlin Heidelberg, p. 239-249 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2004

Granzyme B-induced cell death

Andrade, F., Casciola-Rosen, L. A. & Rosen, A., Jan 1 2004, In : Acta Haematologica. 111, 1-2, p. 28-41 14 p.

Research output: Contribution to journalReview article

2003

El impacto del descubrimiento de la estructura del DNA en reumatología

Translated title of the contribution: The discovery of DNA structure and its importance in rheumatologyAndrade, F. & Sánchez-Guerrero, J., Mar 1 2003, In : Revista de Investigacion Clinica. 55, 2, p. 196-199 4 p.

Research output: Contribution to journalArticle

2002

Distribution of class I and class III MHC antigens in the Tarasco Amerindians

Loeza, F., Vargas-Alarcón, G., Andrade, F., Vergara, Y., Rodríguez-Pérez, J., Ruiz-Morales, J. A., Alarcón-Segovia, D. & Granados, J., Feb 18 2002, In : Human Immunology. 63, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

2001

Adenovirus L4-100K assembly protein is a Granzyme B substrate that potently inhibits Granzyme B-mediated cell death

Andrade, F., Bull, H. G., Thornberry, N. A., Ketner, G. W., Casciola-Rosen, L. A. & Rosen, A., Jan 1 2001, In : Immunity. 14, 6, p. 751-761 11 p.

Research output: Contribution to journalArticle

2000

Apoptosis in systemic lupus erythematosus: Clinical implications

Andrade, F., Casciola-Rosen, L. & Rosen, A., Jan 1 2000, In : Rheumatic Disease Clinics of North America. 26, 2, p. 215-227 13 p.

Research output: Contribution to journalArticle

1999

Cleavage by granzyme B is strongly predictive of autoantigen status: Implications for initiation of autoimmunity

Casciola-Rosen, L., Andrade, F., Ulanet, D., Wong, W. B. & Rosen, A., Sep 20 1999, In : Journal of Experimental Medicine. 190, 6, p. 815-825 11 p.

Research output: Contribution to journalArticle

Immunogenetics of mixed connective tissue disease in a Mexican Mestizo population

Weckmann, A. L., Granados, J., Cardiel, M. H., Andrade, F., Vargas-Alarcón, G., Alcocer-Varela, J. & Alarcón-Segovia, D., Mar 5 1999, In : Clinical and experimental rheumatology. 17, 1, p. 91-94 4 p.

Research output: Contribution to journalArticle

1998

Complotype SC30 is associated with susceptibility to develop ulcerative colitis in Mexicans [1]

Yamamoto-Furusho, J. K., Cantu, C., Vargas-Alarcon, G., Andrade, F., Zuniga, J., Rodriguez, J., Boom, R. & Granados, J., Oct 1 1998, In : Journal of clinical gastroenterology. 27, 2, p. 178-179 2 p.

Research output: Contribution to journalLetter

Granzyme B directly and efficiently cleaves several downstream caspases substrates: Implications for CTL-induced apoptosis

Andrade, F., Roy, S., Nicholson, D., Thornberry, N., Rosen, A. & Casciola-Rosen, L., Apr 1998, In : Immunity. 8, 4, p. 451-460 10 p.

Research output: Contribution to journalArticle

1997

Relationship of anticardiolipin antibodies and antiphospholipid syndrome to HLA-DR7 in Mexican patients with systemic lupus erythematosus (SLE)

Granados, J., Vargas-Alarcón, G., Drenkard, C., Andrade, F., Melín-Aldana, H., Alcocer-Varela, J. & Alarcón-Segovia, D., Jan 1 1997, In : Lupus. 6, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

1996

Independent associations of the HLA-B27 antigen and the complement haplotype SC21 in chronic anterior uveitis

Arellanes, L., Yamamoto-Furusho, J. K., Andrade, F., Vargas-Alarcón, G., Barojas, E., García-Garduño, L. M. & Granados, J., Jan 1 1996, In : Ocular Immunology and Inflammation. 4, 4, p. 203-206 4 p.

Research output: Contribution to journalArticle