Evgeny Izumchenko

Assistant Professor

20062018
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Research Output 2006 2018

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

Ravi, R., Noonan, K. A., Pham, V., Bedi, R., Zhavoronkov, A., Ozerov, I. V., Makarev, E., Artemov, A. V., Wysocki, P. T., Mehra, R., Nimmagadda, S., Marchionni, L., Sidransky, D., Borrello, I. M., Izumchenko, E. & Bedi, A., Dec 1 2018, In : Nature Communications. 9, 1, 741

Research output: Contribution to journalArticle

beta factor
CTLA-4 Antigen
antibodies
Transforming Growth Factor beta
Immunotherapy

Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance

Stein-O'Brien, G., Kagohara, L. T., Li, S., Thakar, M., Ranaweera, R., Ozawa, H., Cheng, H., Considine, M., Schmitz, S., Favorov, A. V., Danilova, L. V., Califano, J. A., Izumchenko, E., Gaykalova, D. A., Chung, C. H. & Fertig, E. J., May 23 2018, In : Genome Medicine. 10, 1, 37

Research output: Contribution to journalArticle

Epigenomics
DNA Methylation
Molecular Dynamics Simulation
RNA Sequence Analysis
Phenotype

Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1

Maldonado, L. , Brait, M. , Izumchenko, E. , Begum, S. , Chatterjee, A. , Sen, T. , Loyo, M. , Barbosa, A. , Poeta, M. L. , Makarev, E. , Zhavoronkov, A. , Fazio, V. M. , Angioli, R. , Rabitti, C. , Ongenaert, M. , Van Criekinge, W. , Noordhuis, M. G. , de Graeff, P. , Wisman, G. B. A. , van der Zee, A. G. J. & 1 others Hoque, M. O., Oct 1 2018, In : Cancer Letters. 433, p. 242-251 10 p.

Research output: Contribution to journalArticle

Epigenomics
Ovarian Neoplasms
Methylation
Epithelium
Cystadenoma

Use of deep neural network ensembles to identify embryonicfetal transition markers: Repression of COX7A1 in embryonic and cancer cells

West, M. D. , Labat, I. , Sternberg, H. , Larocca, D. , Nasonkin, I. , Chapman, K. B. , Singh, R. , Makarev, E. , Aliper, A. , Kazennov, A. , Alekseenko, A. , Shuvalov, N. , Cheskidova, E. , Alekseev, A. , Artemov, A. , Putin, E. , Mamoshina, P. , Pryanichnikov, N. , Larocca, J. , Copeland, K. & 3 others Izumchenko, E., Korzinkin, M. & Zhavoronkov, A., Jan 1 2018, In : Oncotarget. 9, 8, p. 7796-7811 16 p.

Research output: Contribution to journalArticle

Stem Cells
Cell Line
Neoplasms
Pluripotent Stem Cells
Gene Knockout Techniques

Vive la radiorésistance! Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization

Cortese, F. , Klokov, D. , Osipov, A. , Stefaniak, J. , Moskalev, A. , Schastnaya, J. , Cantor, C. , Aliper, A. , Mamoshina, P. , Ushakov, I. , Sapetsky, A. , Vanhaelen, Q. , Alchinova, I. , Karganov, M. , Kovalchuk, O. , Wilkins, R. , Shtemberg, A. , Moreels, M. , Baatout, S. , Izumchenko, E. & 10 others de Magalhães, J. P., Artemov, A. V., Costes, S. V., Beheshti, A., Mao, X. W., Pecaut, M. J., Kaminskiy, D., Ozerov, I. V., Scheibye-Knudsen, M. & Zhavoronkov, A., Jan 1 2018, In : Oncotarget. 9, 18, p. 14692-14722 31 p.

Research output: Contribution to journalArticle

Radiobiology
Space Flight
DNA Damage
Research
Linear Energy Transfer