Esteban Mezey

Professor

1967 …2019
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Ethanol Medicine & Life Sciences
Liver Medicine & Life Sciences
Alcohol Dehydrogenase Medicine & Life Sciences
Rats Chemical Compounds
Collagen Medicine & Life Sciences
Alcohols Medicine & Life Sciences
Alcoholism Medicine & Life Sciences
Acetaldehyde Medicine & Life Sciences

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Research Output 1967 2019

Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity

Li, L., Knutsdottir, H., Hui, K., Weiss, M. J., He, J., Philosophe, B., Cameron, A. M., Wolfgang, C. L., Pawlik, T. M., Ghiaur, G., Ewald, A. J., Mezey, E., Bader, J. S. & Selaru, F. M., Jan 24 2019, In : JCI Insight. 4, 2, Y.

Research output: Contribution to journalArticle

Open Access
Organoids
Liver Neoplasms
Pharmaceutical Preparations
Neoplasms
Drug Therapy

Elevated mitochondrial activity distinguishes fibrogenic hepatic stellate cells and sensitizes for selective inhibition by mitotropic doxorubicin

Gajendiran, P., Vega, L. I., Itoh, K., Sesaki, H., Vakili, M. R., Lavasanifar, A., Hong, K., Mezey, E. & Ganapathy, S., Jan 1 2018, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Doxorubicin
Liver Cirrhosis
Energy Metabolism
Mitochondrial Membrane Potential

Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury

Cho, Y. E., Im, E. J., Moon, P. G., Mezey, E., Song, B. J. & Baek, M. C., Feb 1 2017, In : PLoS One. 12, 2, e0172463.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Biomarkers
Liver
biomarkers
alcohols

The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans

Liu, L., Dong, Y., Ye, M., Jin, S., Yang, J., Joosse, M. E., Sun, Y., Zhang, J., Lazarev, M., Brant, S. R., Safar, B., Marohn, M., Mezey, E. & Li, X., Jun 1 2017, In : Journal of Crohn's & colitis. 11, 6, p. 737-750 14 p.

Research output: Contribution to journalArticle

Inflammasomes
Inflammatory Bowel Diseases
Interleukin-10
Glyburide
Colitis

Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B−/− (Wilson disease) mice

Hamilton, J., Koganti, L., Muchenditsi, A., Pendyala, V. S., Huso, D., Hankin, J., Murphy, R. C., Huster, D., Merle, U., Mangels, C., Yang, N., Potter, J. J., Mezey, E. & Lutsenko, S., 2016, In : Hepatology. 63, 6, p. 1828-1841 14 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Hepatolenticular Degeneration
Liver Diseases
Copper
Cytoplasmic and Nuclear Receptors