Ernst W Spannhake

Professor Emeritus

1976 …2019

Research output per year

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Research Output

2019
2018

The Acute Effects of Age and Particulate Matter Exposure on Heart Rate and Heart Rate Variability in Mice

Bennett, B. A., Spannhake, E. W., Rule, A. M., Breysse, P. N. & Tankersley, C. G., May 17 2018, (Accepted/In press) In : Cardiovascular Toxicology. p. 1-13 13 p.

Research output: Contribution to journalArticle

2017

Perioperative participation of orthopedic patients and surgical staff in a nasal decolonization intervention to reduce Staphylococcus spp surgical site infections

Mullen, A., Wieland, H. J., Wieser, E. S., Spannhake, E. W. & Marinos, R. S., May 1 2017, In : American Journal of Infection Control. 45, 5, p. 554-556 3 p.

Research output: Contribution to journalArticle

2014

Reduction of nasal Staphylococcus aureus carriage in health care professionals by treatment with a nonantibiotic, alcohol-based nasal antiseptic

Steed, L. L., Costello, J., Lohia, S., Jones, T., Spannhake, E. W. & Nguyen, S., 2014, In : American Journal of Infection Control. 42, 8, p. 841-846 6 p.

Research output: Contribution to journalArticle

2013

Characterization of a portable method for the collection of exhaled breath condensate and subsequent analysis of metal content

Fox, J. R., Spannhake, E. W., Macri, K. K., Torrey, C. M., Mihalic, J. N., Eftim, S. E., Lees, P. S. & Geyh, A. S., Apr 2013, In : Environmental Sciences: Processes and Impacts. 15, 4, p. 721-729 9 p.

Research output: Contribution to journalArticle

2012

Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells

Zhao, J., Chen, Q., Li, H., Myerburg, M., Spannhake, E. W., Natarajan, V. & Zhao, Y., Jan 2012, In : Cellular Signalling. 24, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

2011
2009

Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrierdisruption and lung injury

He, D., Su, Y., Usatyuk, P. V., Spannhake, E. W., Kogut, P., Solway, J., Natarajan, V. & Zhao, Y., Sep 4 2009, In : Journal of Biological Chemistry. 284, 36, p. 24123-24132 10 p.

Research output: Contribution to journalArticle

Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells

Zhao, Y., Usatyuk, P. V., Gorshkova, I. A., He, D., Wang, T., Moreno-Vinasco, L., Geyh, A. S., Breysse, P. N., Samet, J. M., Spannhake, E. W., Garcia, J. G. N. & Natarajan, V., Jan 1 2009, In : American Journal of Respiratory Cell and Molecular Biology. 40, 1, p. 19-30 12 p.

Research output: Contribution to journalArticle

2008

Interactions of Pollutants with the Epithelium

Spannhake, E. W., May 14 2008, The Pulmonary Epithelium in Health and Disease. John Wiley and Sons, p. 275-299 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E2 release via C/EBPβ in human bronchial epithelial cells

He, D., Natarajan, V., Stern, R., Gorshkova, I. A., Solway, J., Spannhake, E. W. & Zhao, Y., May 15 2008, In : Biochemical Journal. 412, 1, p. 153-162 10 p.

Research output: Contribution to journalArticle

2007

Lysophosphatidic acid induces interleukin-13 (IL-13) receptor α2 expression and inhibits IL-13 signaling in primary human bronchial epithelial cells

Zhao, Y., He, D., Zhao, J., Wang, L., Leff, A. R., Spannhake, E. W., Georas, S. & Natarajan, V., Apr 6 2007, In : Journal of Biological Chemistry. 282, 14, p. 10172-10179 8 p.

Research output: Contribution to journalArticle

Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC δ and E-cadherin

Zhao, Y., He, D., Stern, R., Usatyuk, P. V., Spannhake, E. W., Salgia, R. & Natarajan, V., Nov 2007, In : Cellular Signalling. 19, 11, p. 2329-2338 10 p.

Research output: Contribution to journalArticle

2006

Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells

Saatian, B., Zhao, Y., He, D., Georas, S. N., Watkins, T., Spannhake, E. W. & Natarajan, V., Feb 1 2006, In : Biochemical Journal. 393, 3, p. 657-668 12 p.

Research output: Contribution to journalArticle

Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-κB activation and interleukin-8 secretion in human bronchial epithelial cells

Zhao, Y., Usatyuk, P. V., Cummings, R., Saatian, B., He, D., Watkins, T., Morris, A., Spannhake, E. W., Brindley, D. N. & Natarajan, V., Jan 15 2005, In : Biochemical Journal. 385, 2, p. 493-502 10 p.

Research output: Contribution to journalArticle

Signal transduction of phorbol 12-myristate 13-acetate (PMA)-induced growth inhibition of human monocytic leukemia THP-1 cells is reactive oxygen dependent

Traore, K., Trush, M. A., George, M., Spannhake, E. W., Anderson, W. & Asseffa, A., Aug 2005, In : Leukemia Research. 29, 8, p. 863-879 17 p.

Research output: Contribution to journalArticle

2004

mRNA for genes associated with antigen presentation are expressed by human middle meatal epithelial cells in culture

Lane, A. P., Saatian, B., Yu, X. Y. & Spannhake, E. W., Oct 2004, In : Laryngoscope. 114, 10 I, p. 1827-1832 6 p.

Research output: Contribution to journalArticle

Protein kinase Cδ mediates lysophosphatidic acid-induced NF-κB activation and interleukin-8 secretion in human bronchial epithelial cells

Cummings, R., Zhao, Y., Jacoby, D., Spannhake, E. W., Ohba, M., Garcia, J. G. N., Watkins, T., He, D., Saatian, B. & Natarajan, V., Sep 24 2004, In : Journal of Biological Chemistry. 279, 39, p. 41085-41094 10 p.

Research output: Contribution to journalArticle

2001

Repetitive ozone exposure of young adults: Evidence of persistent small airway dysfunction

Frank, R., Liu, M. C. H., Spannhake, E. W., Mlynarek, S., Macri, K. & Weinmann, G. G., Oct 1 2001, In : American Journal of Respiratory and Critical Care Medicine. 164, 7, p. 1253-1260 8 p.

Research output: Contribution to journalArticle

2000

Tissue prostanoids as biomarkers for chemoprevention of colorectal neoplasia: Correlation between prostanoid synthesis and clinical response in familial adenomatous polyposis

Yang, V. W., Geiman, D. E., Hubbard, W. C., Spannhake, E. W., Hylind, L. M., Hamilton, S. R. & Giardiello, F. M., Jan 2000, In : Prostaglandins and Other Lipid Mediators. 60, 1-3, p. 83-96 14 p.

Research output: Contribution to journalArticle

1998

Correlates of infection control practices in dentistry

Gershon, R. R. M., Karkashian, C., Vlahov, D., Grimes, M. & Spannhake, E. W., 1998, In : American Journal of Infection Control. 26, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

Prostaglandin levels in human colorectal mucosa: Effects of sulindac in patients with familial adenomatous polyposis

Giardiello, F. M., Spannhake, E. W., Dubois, R. N., Hylind, L. M., Robinson, C. R., Hubbard, W. C., Hamilton, S. R. & Yang, V. W., 1998, In : Digestive Diseases and Sciences. 43, 2, p. 311-316 6 p.

Research output: Contribution to journalArticle

Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis

Yang, V. W., Shields, J. M., Hamilton, S. R., Spannhake, E. W., Hubbard, W. C., Hylind, L. M., Robinson, C. R. & Giardiello, F. M., Apr 15 1998, In : Cancer Research. 58, 8, p. 1750-1753 4 p.

Research output: Contribution to journalArticle

1996

Down-regulation of canine airway mast cell function following exposure to ozone in vivo

Spannhake, E. W., 1996, In : Experimental Lung Research. 22, 2, p. 163-178 16 p.

Research output: Contribution to journalArticle

1995

Expression of ICAM-1 in airway epithelium after acute ozone exposure in the mouse

Takahashi, N., Yu, X. Y., Schofield, B. H., Kleeberger, S. R., Scott, A. L., Hasegawa, S. & Spannhake, E. W., 1995, In : Journal of Applied Physiology. 79, 5, p. 1753-1761 9 p.

Research output: Contribution to journalArticle

Specific binding of endothelin-1 to canine tracheal epithelial cells in culture

Ninomiya, H., Yu, X. Y., Uchida, Y., Hasegawa, S. & Spannhake, E. W., 1995, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 268, 3 12-3

Research output: Contribution to journalArticle

The 5-lipoxygenase pathway in cultured human intestinal epithelial cells

Cortese, J. F., Spannhake, E. W., Eisinger, W., Potter, J. J. & Yang, V. W., 1995, In : Prostaglandins. 49, 3, p. 155-166 12 p.

Research output: Contribution to journalArticle

The effects of ozone on immune function

Jakab, G. J., Spannhake, E. W., Canning, B. J., Kleeberger, S. R. & Gilmour, M. I., 1995, In : Environmental Health Perspectives. 103, SUPPL. 2, p. 77-89 13 p.

Research output: Contribution to journalArticle

1994

Modulation of bronchial epithelial cell barrier function by in vitro ozone exposure

Yu, X. Y., Takahashi, N., Croxton, T. L. & Spannhake, E. W., 1994, In : Environmental Health Perspectives. 102, 12, p. 1068-1072 5 p.

Research output: Contribution to journalArticle

Physiologic modulation of bronchial epithelial cell barrier function by polycationic exposure.

Yu, X. Y., Schofield, B. H., Croxton, T., Takahashi, N., Gabrielson, E. & Spannhake, E. W., Aug 1994, In : American Journal of Respiratory Cell and Molecular Biology. 11, 2, p. 188-198 11 p.

Research output: Contribution to journalArticle

Soluble intracellular adhesion molecule 1 in bronchoalveolar lavage fluid of allergic subjects following segmental antigen challenge

Takahashi, N., Liu, M. C., Proud, D., Yu, X. Y., Hasegawa, S. & Spannhake, E. W., Sep 1994, In : American Journal of Respiratory and Critical Care Medicine. 150, 3, p. 704-709 6 p.

Research output: Contribution to journalArticle

1992

Endothelin-1 induces stimulation of prostaglandin synthesis in cells obtained from canine airways by bronchoalveolar lavage

Ninomiya, H., Hasegawa, S., Yu, X. Y. & Spannhake, E. W., 1992, In : Prostaglandins. 43, 5, p. 401-411 11 p.

Research output: Contribution to journalArticle

1991

Contractile responses of guinea pig trachea to oxybarbiturates and thiobarbiturates

Curry, C., Lenox, W. C., Spannhake, E. W. & Hirshman, C. A., 1991, In : Anesthesiology. 75, 4, p. 679-683 5 p.

Research output: Contribution to journalArticle

Mediators, initiating the inflammatory response, released in organ culture by full-thickness human skin explants exposed to the irritant, sulfur mustard

Rikimaru, T., Nakamura, M., Yano, T., Beck, G., Habicht, G. S., Rennie, L. L., Widra, M., Hirshman, C. A., Boulay, M. G., Spannhake, E. W., Lazarus, G. S., Pula, P. J. & Dannenberg, A. M., Jun 1991, In : Journal of Investigative Dermatology. 96, 6, p. 888-897 10 p.

Research output: Contribution to journalArticle

1990