Eric Spear

Research Associate

20002019

Research output per year

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Research Output

A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24

Spear, E., Alford, R. F., Babatz, T. D., Wood, K. M., Mossberg, O. W., Odinammadu, K., Shilagardi, K., Gray, J. J. & Michaelis, S. D., Jan 1 2019, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

  • ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin a cleavage activity and/or protein stability

    Spear, E., Hsu, E. T., Nie, L., Carpenter, E. P., Hrycyna, C. A. & Michaelis, S. D., Jul 1 2018, In : DMM Disease Models and Mechanisms. 11, 7, Y.

    Research output: Contribution to journalArticle

  • Degradation signals for ubiquitin-proteasome dependent cytosolic protein quality control (CytoQC) in yeast

    Maurer, M. J., Spear, E. D., Yu, A. T., Lee, E. J., Shahzad, S. & Michaelis, S., Jul 1 2016, In : G3: Genes, Genomes, Genetics. 6, 7, p. 1853-1866 14 p.

    Research output: Contribution to journalArticle

  • Erratum for the report: "Mapping the cellular response to small molecules using chemogenomic fitness signatures" (Science (2014) (208-211))

    Lee, A. Y., St.Onge, R. P., Proctor, M. J., Wallace, I. M., Nile, A. H., Spagnuolo, P. A., Jitkova, Y., Gronda, M., Wu, Y., Kim, M. K., Cheung-Ong, K., Torres, N. P., Spear, E. D., Han, M. K. L., Schlecht, U., Suresh, S., Duby, G., Heisler, L. E., Surendra, A., Fung, E. & 19 others, Urbanus, M. L., Gebbia, M., Lissina, E., Miranda, M., Chiang, J. H., Aparicio, A. M., Zeghouf, M., Davis, R. W., Cherfils, J., Boutry, M., Kaiser, C. A., Cummins, C. L., Trimble, W. S., Brown, G. W., Schimmer, A. D., Bankaitis, V. A., Nislow, C., Bader, G. D. & Giaever, G., Jan 1 2014, In : Science. 344, 6186, 1255771.

    Research output: Contribution to journalComment/debate

    Mapping the cellular response to small molecules using chemogenomic fitness signatures

    Lee, A. Y., St.Onge, R. P., Proctor, M. J., Wallace, I. M., Nile, A. H., Spagnuolo, P. A., Jitkova, Y., Gronda, M., Wu, Y., Kim, M. K., Cheung-Ong, K., Torres, N. P., Spear, E. D., Han, M. K. L., Schlecht, U., Suresh, S., Duby, G., Heisler, L. E., Surendra, A., Fung, E. & 19 others, Urbanus, M. L., Gebbia, M., Lissina, E., Miranda, M., Chiang, J. H., Aparicio, A. M., Zeghouf, M., Davis, R. W., Cherfils, J., Boutry, M., Kaiser, C. A., Cummins, C. L., Trimble, W. S., Brown, G. W., Schimmer, A. D., Bankaitis, V. A., Nislow, C., Bader, G. D. & Giaever, G., Jan 1 2014, In : Science. 344, 6180, p. 208-211 4 p.

    Research output: Contribution to journalArticle