Research Output 1992 2018

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2018

Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer

Benzon, B., Glavaris, S. A., Simons, B. W., Hughes, R. M., Ghabili, K., Mullane, P., Miller, R., Nugent, K., Shinder, B., Tosoian, J., Fuchs, E. J., Tran, P. T., Hurley, P. J., Vuica-Ross, M., Schaeffer, E. M., Drake, C. G. & Ross, A. E. Mar 20 2018 (Accepted/In press) In : Prostate Cancer and Prostatic Diseases. p. 1-11 11 p.

Research output: Contribution to journalArticle

Cryosurgery
Prostatic Neoplasms
Hormones
Neoplasms
Blocking Antibodies
Bone Marrow Transplantation
Cyclophosphamide
Tissue Donors
Confidence Intervals
Transplants

Immunotherapy of myelodysplastic syndrome: You can run, but you can't hide

Fuchs, E. J. Mar 1 2018 In : Clinical Cancer Research. 24, 5, p. 991-993 3 p.

Research output: Contribution to journalArticle

decitabine
Myelodysplastic Syndromes
Myeloid Cells
Immunotherapy
Testicular Neoplasms

Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium (HAPLO2016), San Diego, California, December 1, 2016

Al Malki, M. M., Jones, R., Ma, Q., Lee, D., Reisner, Y., Miller, J. S., Lang, P., Hongeng, S., Hari, P., Strober, S., Yu, J., Maziarz, R., Mavilio, D., Roy, D. C., Bonini, C., Champlin, R. E., Fuchs, E. J. & Ciurea, S. O. Jan 1 2018 (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Tissue Donors
T-Lymphocytes
Transplantation
Hematopoietic Stem Cell Transplantation
Tacrolimus
Graft vs Host Disease
Bone Marrow Transplantation
Transplantation
Arm
Graft vs Host Disease
Cyclophosphamide
Transplantation
Recurrence
Bone Marrow
Graft vs Host Disease
Bone Marrow Transplantation
Cyclophosphamide
Disease-Free Survival
Confidence Intervals

Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Children and Adolescents with Fanconi Anemia

Bonfim, C., Ribeiro, L., Nichele, S., Loth, G., Bitencourt, M., Koliski, A., Kuwahara, C., Fabro, A. L., Pereira, N. F., Pilonetto, D., Thakar, M., Kiem, H. P., Page, K., Fuchs, E. J., Eapen, M. & Pasquini, R. Feb 1 2017 In : Biology of Blood and Marrow Transplantation. 23, 2, p. 310-317 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Bone Marrow Transplantation
Cyclophosphamide
Transplants
Antilymphocyte Serum

Haplotype Counting for Sensitive Chimerism Testing: Potential for Early Leukemia Relapse Detection

Debeljak, M., Mocci, E., Morrison, M. C., Pallavajjalla, A., Beierl, K., Amiel, M., Noë, M., Wood, L. D., Lin, M. T., Gocke, C. D., Klein, A. P., Fuchs, E. J., Jones, R. J. & Eshleman, J. R. May 1 2017 In : Journal of Molecular Diagnostics. 19, 3, p. 427-436 10 p.

Research output: Contribution to journalArticle

Chimerism
Haplotypes
Leukemia
Recurrence
Bone Marrow Transplantation

Low immunosuppressive burden after HLA-matched related or unrelated BMT using posttransplantation cyclophosphamide

Kanakry, C. G. , Bolaños-Meade, J. , Kasamon, Y. L. , Zahurak, M. , Durakovic, N. , Furlong, T. , Mielcarek, M. , Medeot, M. , Gojo, I. , Smith, B. D. , Kanakry, J. A. , Borrello, I. M. , Brodsky, R. A. , Gladstone, D. E. , Huff, C. A. , Matsui, W. H. , Swinnen, L. J. , Cooke, K. R. , Ambinder, R. F. , Fuchs, E. J. & 6 others De Lima, M. J., Andersson, B. S., Varadhan, R., O'Donnell, P. V., Jones, R. J. & Luznik, L. Mar 9 2017 In : Blood. 129, 10, p. 1389-1393 5 p.

Research output: Contribution to journalArticle

Busulfan
Immunosuppressive Agents
Cyclophosphamide
Immunosuppression
Grafts
Histocompatibility
Homologous Transplantation
Bone Marrow Transplantation
Tissue Donors
Allografts

Mobilized peripheral blood stem cells versus unstimulated bone marrow as a graft source for T-cell–replete haploidentical donor transplantation using post-transplant cyclophosphamide

Bashey, A. , Zhang, M. J. , McCurdy, S. R. , St Martin, A. , Argall, T. , Anasetti, C. , Ciurea, S. O. , Fasan, O. , Gaballa, S. , Hamadani, M. , Munshi, P. , Al Malki, M. M. , Nakamura, R. , O'Donnell, P. V. , Perales, M. A. , Raj, K. , Romee, R. , Rowley, S. , Rocha, V. , Salit, R. B. & 4 others Solh, M., Soiffer, R. J., Fuchs, E. J. & Eapen, M. Sep 10 2017 In : Journal of Clinical Oncology. 35, 26, p. 3002-3009 8 p.

Research output: Contribution to journalArticle

Cyclophosphamide
Transplantation
Bone Marrow
Tissue Donors
T-Lymphocytes
Hematologic Neoplasms
Bone Marrow Transplantation
Cyclophosphamide
Young Adult
Transplantation
Bone Marrow Transplantation
Cyclophosphamide
Young Adult
Pediatrics
Transplants
2016

Allogeneic stem cell transplantation for sickle cell disease

Robinson, T. M. & Fuchs, E. J. Aug 4 2016 (Accepted/In press) In : Current Opinion in Hematology.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Stem Cell Transplantation
Transplants
Hematopoietic Stem Cell Transplantation
Graft vs Host Disease

Anti-CD45 radioimmunotherapy without TBI before transplantation facilitates persistent haploidentical donor engraftment

Orozco, J. J., Kenoyer, A., Balkin, E. R., Gooley, T. A., Hamlin, D. K., Wilbur, D. S., Hylarides, M. D., Frost, S. H. L., Mawad, R., O'Donnell, P., Sandmaier, B. M., Fuchs, E. J., Luznik, L., Green, D. J., Gopal, A. K., Press, O. W. & Pagel, J. M. Jan 21 2016 In : Blood. 127, 3, p. 352-359 8 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Whole-Body Irradiation
Bone Marrow Transplantation
Bone
Transplantation

Comparable outcomes with marrow or peripheral blood as stem cell sources for hematopoietic cell transplantation from haploidentical donors after non-ablative conditioning: a matched-pair analysis

O'Donnell, P. V., Eapen, M., Horowitz, M. M., Logan, B. R., DiGilio, A., Brunstein, C., Fuchs, E. J., Flowers, M. E. D., Salit, R., Raj, K., Pagliuca, A., Bradstock, K., Granata, A., Castagna, L., Furst, S. & Blaise, D. Aug 15 2016 (Accepted/In press) In : Bone Marrow Transplantation.

Research output: Contribution to journalArticle

Medical Oncology
Transplantation
Bone Marrow

Haploidentical bone marrow and stem cell transplantation: Experience with post-transplantation cyclophosphamide

Robinson, T. M., O'Donnell, P. V., Fuchs, E. J. & Luznik, L. Apr 1 2016 In : Seminars in Hematology. 53, 2, p. 90-97 8 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Bone Marrow Transplantation
Cyclophosphamide
Transplantation
HLA Antigens

Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States

Apperley, J., Niederwieser, D., Huang, X. J., Nagler, A., Fuchs, E., Szer, J. & Kodera, Y. Jan 1 2016 In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 22, 1, p. 23-26 4 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
European Union
Transplantation
Bone Marrow
Transplants

Modern approaches to HLA-haploidentical blood or marrow transplantation

Kanakry, C. G., Fuchs, E. J. & Luznik, L. Jan 1 2016 In : Nature Reviews Clinical Oncology. 13, 1, p. 10-24 15 p.

Research output: Contribution to journalArticle

HLA Antigens
Bone Marrow Transplantation
Transplantation
Bone Marrow
Siblings
Bone Marrow Transplantation
Cyclophosphamide
Transplantation
Tissue Donors
Neoplasms

Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014, San Francisco, California, December 4, 2014

Al Malki, M. M., Horowitz, M., Handgretinger, R., Leung, W., Roy, D. C., Huang, X. J., Fuchs, E., Locatelli, F., Blaise, D., Mineishi, S., Martelli, M., Miller, J., June, C., Ai, H. S., Luznik, L., Mavilio, D., Lugli, E., van den Brink, M. R. M., Champlin, R. E. & Ciurea, S. O. Apr 1 2016 In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 22, 4, p. 594-604 11 p.

Research output: Contribution to journalArticle

San Francisco
Stem Cell Transplantation
Transplantation
Recurrence
Unrelated Donors

Reduced-intensity transplantation for lymphomas using haploidentical related donors versus HLA-matched sibling donors: A center for international blood and marrow transplant research analysis

Ghosh, N. , Karmali, R. , Rocha, V. , Ahn, K. W. , DiGilio, A. , Hari, P. N. , Bachanova, V. , Bacher, U. , Dahi, P. , De Lima, M. , D'Souza, A. , Fenske, T. S. , Ganguly, S. , Kharfan-Dabaja, M. A. , Prestidge, T. D. , Savani, B. N. , Smith, S. M. , Sureda, A. M. , Waller, E. K. , Jaglowski, S. & 7 others Herrera, A. F., Armand, P., Salit, R. B., Wagner-Johnston, N. D., Fuchs, E., Bolaños-Meade, J. & Hamadani, M. Sep 10 2016 In : Journal of Clinical Oncology. 34, 26, p. 3141-3149 9 p.

Research output: Contribution to journalArticle

Cell Transplantation
Siblings
Lymphoma
Transplantation
Bone Marrow
Hematopoietic Stem Cell Transplantation
European Union
Transplantation
Bone Marrow
Transplants
Busulfan
Drug Monitoring
Cyclophosphamide
Transplantation
Pharmacokinetics

The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: Multiple myeloma, lymphoma, and acute leukemia

Boyiadzis, M. , Bishop, M. R. , Abonour, R. , Anderson, K. C. , Ansell, S. M. , Avigan, D. , Barbarotta, L. , Barrett, A. J. , Besien, K. , Bergsagel, P. L. , Borrello, I. , Brody, J. , Brufsky, J. , Cairo, M. , Chari, A. , Cohen, A. , Cortes, J. , Forman, S. J. , Friedberg, J. W. , Fuchs, E. J. & 28 others Gore, S. D., Jagannath, S., Kahl, B. S., Kline, J., Kochenderfer, J. N., Kwak, L. W., Levy, R., Lima, M., Litzow, M. R., Mahindra, A., Miller, J., Munshi, N. C., Orlowski, R. Z., Pagel, J. M., Porter, D. L., Russell, S. J., Schwartz, K., Shipp, M. A., Siegel, D., Stone, R. M., Tallman, M. S., Timmerman, J. M., Rhee, F., Waller, E. K., Welsh, A., Werner, M., Wiernik, P. H. & Dhodapkar, M. V. Dec 20 2016 In : Journal for ImmunoTherapy of Cancer. 4, 1, 90

Research output: Contribution to journalArticle

Hematologic Neoplasms
Multiple Myeloma
Immunotherapy
Lymphoma
Leukemia
2015
Adoptive Transfer
Multiple Myeloma
Immunity
Bone Marrow
Lymphocytes
Hematologic Neoplasms
Cyclophosphamide
Transplantation
Bone Marrow
Disease-Free Survival

Haplo graft engineering: Sculpting to a T

Fuchs, E. J. Apr 9 2015 In : Blood. 125, 15, p. 2315-2316 2 p.

Research output: Contribution to journalArticle

T-cells
Grafts
T-Lymphocytes
Transplants
Antiviral Agents

Haploidentical transplant with posttransplant cyclophosphamide vs matched unrelated donor transplant for acute myeloid leukemia

Ciurea, S. O. , Zhang, M. J. , Bacigalupo, A. A. , Bashey, A. , Appelbaum, F. R. , Aljitawi, O. S. , Armand, P. , Antin, J. H. , Chen, J. , Devine, S. M. , Fowler, D. H. , Luznik, L. , Nakamura, R. , O'Donnell, P. V. , Perales, M. A. , Pingali, S. R. , Porter, D. L. , Riches, M. R. , Ringdén, O. T. H. , Rocha, V. & 6 others Vij, R., Weisdorf, D. J., Champlin, R. E., Horowitz, M. M., Fuchs, E. J. & Eapen, M. Aug 20 2015 In : Blood. 126, 8, p. 1033-1040 8 p.

Research output: Contribution to journalArticle

Unrelated Donors
Transplants
Acute Myeloid Leukemia
Cyclophosphamide
Graft vs Host Disease
Cyclophosphamide
Hematologic Neoplasms
Transplantation
Bone Marrow
Tissue Donors
Cyclophosphamide
Transplantation
Bone Marrow
Graft vs Host Disease
Disease-Free Survival

Recent developments in HLA-haploidentical transplantations

Showel, M. & Fuchs, E. J. Jun 1 2015 In : Best Practice and Research: Clinical Haematology. 28, 2-3, p. 141-146 6 p.

Research output: Contribution to journalArticle

Stem cells
Cyclophosphamide
Transplantation
Availability
Hematopoietic Stem Cell Transplantation

Risk-stratified outcomes of nonmyeloablative HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide

McCurdy, S. R. , Kanakry, J. A. , Showel, M. M. , Tsai, H. L. , Bolaños-Meade, J. , Rosner, G. L. , Kanakry, C. G. , Perica, K. , Symons, H. J. , Brodsky, R. A. , Gladstone, D. E. , Huff, C. A. , Pratz, K. W. , Prince, G. T. , Dezern, A. E. , Gojo, I. , Matsui, W. H. , Borrello, I. , McDevitt, M. A. , Swinnen, L. J. & 7 others Smith, B. D., Levis, M. J., Ambinder, R. F., Luznik, L., Jones, R. J., Fuchs, E. J. & Kasamon, Y. L. May 7 2015 In : Blood. 125, 19, p. 3024-3031 8 p.

Research output: Contribution to journalArticle

Cyclophosphamide
Blood
Transplantation
Bone Marrow
Disease-Free Survival
2014
Bone Marrow Transplantation
Fetal Blood
Cost-Benefit Analysis
Transplantation
Bone Marrow

Mismatched related and unrelated donors for allogeneic hematopoietic cell transplantation for adults with hematologic malignancies

Eapen, M., O'Donnell, P., Brunstein, C. G., Wu, J., Barowski, K., Mendizabal, A. & Fuchs, E. J. Oct 1 2014 In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 20, 10, p. 1485-1492 8 p.

Research output: Contribution to journalArticle

Unrelated Donors
Cell Transplantation
Hematologic Neoplasms
Fetal Blood
Tissue Donors
Graft vs Host Disease
Grafts
Cyclophosphamide
Transplantation
Bone Marrow

Successful transplantation of kidney allografts in sensitized rats after syngeneic hematopoietic stem cell transplantation and fludarabine

Fu, Y., Sun, Z., Fuchs, E. J., Wang, Y., Shen, Z. Y., Maeda, H., Lin, Q., Warren, D. S., Williams, G. M. & Montgomery, R. A. Oct 1 2014 In : American Journal of Transplantation. 14, 10, p. 2375-2383 9 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Kidney Transplantation
Allografts
Antibodies
Tissue Donors

Transplantation tolerance: From theory to clinic

Fuchs, E. J. 2014 In : Immunological Reviews. 258, 1, p. 64-79 16 p.

Research output: Contribution to journalArticle

Transplantation Tolerance
Tissue Donors
Chimerism
Organ Transplantation
Graft vs Host Disease

Aldehyde dehydrogenase expression drives human regulatory T cell resistance to posttransplantation cyclophosphamide

Kanakry, C. G., Ganguly, S., Zahurak, M., Bolaños-Meade, J., Thoburn, C., Perkins, B., Fuchs, E. J., Jones, R. J., Hess, A. D. & Luznik, L. Nov 13 2013 In : Science Translational Medicine. 5, 211, 211ra157

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Regulatory T-Lymphocytes
Cyclophosphamide
Graft vs Host Disease
T-Lymphocytes
Antineoplastic Combined Chemotherapy Protocols
Transplantation Conditioning
Histiocytic Sarcoma
Vidarabine
Antibodies, Monoclonal, Humanized
Peripheral T-Cell Lymphoma
Transplantation
Bone Marrow
Tissue Donors
Confidence Intervals
HLA Antigens
Transplantation
Antibodies
Tissue Donors
Unrelated Donors
Transplantation Conditioning
Lymphocyte Depletion
Hematopoietic Stem Cell Transplantation
Homologous Transplantation