Emily Grace Baxi

Research Associate

20072018
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Research Output 2007 2018

2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

ITALSGEN Consortium, Genomic Translation for ALS Care (GTAC) Consortium, ALS Sequencing Consortium, NYGC ALS Consortium, Answer ALS Foundation, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, SLAGEN Consortium, French ALS Consortium & Project MinE ALS Sequencing Consortium, Mar 21 2018, In : Neuron. 97, 6, p. 1268-1283.e6

Research output: Contribution to journalArticle

Kinesin
Genome
Mutation
Genes
Genome-Wide Association Study
2017

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

Baxi, E. G., Debruin, J., Jin, J., Strasburger, H. J., Smith, M. D., Orthmann-Murphy, J. L., Schott, J. T., Fairchild, A. N., Bergles, D. E. & Calabresi, P., 2017, (Accepted/In press) In : GLIA.

Research output: Contribution to journalArticle

Cuprizone
Oligodendroglia
Demyelinating Diseases
Stem Cells
Corpus Callosum
2016
Myelin Proteins
Oligodendroglia
Neurology
Rats
Assays

Systemic tolerance mediated by melanoma brain tumors is reversible by radiotherapy and vaccination

Jackson, C. M., Kochel, C. M., Nirschl, C. J., Durham, N. M., Ruzevick, J., Alme, A., Francica, B. J., Elias, J., Daniels, A., Dubensky, T. W., Lauer, P., Brockstedt, D. G., Baxi, E. G., Calabresi, P., Taube, J. M., Pardo-Villamizar, C. A., Brem, H., Pardoll, A. M., Lim, M. & Drake, C. G., Mar 1 2016, In : Clinical Cancer Research. 22, 5, p. 1161-1172 12 p.

Research output: Contribution to journalArticle

Central Nervous System Neoplasms
Brain Neoplasms
Melanoma
Vaccination
Radiotherapy
2015

Disparate effects of mesenchymal stem cells in experimental autoimmune encephalomyelitis and cuprizone-induced demyelination

Glenn, J. D., Smith, M. D., Kirby, L. A., Baxi, E. G. & Whartenby, K., Sep 25 2015, In : PLoS One. 10, 9, e0139008.

Research output: Contribution to journalArticle

Cuprizone
Autoimmune Experimental Encephalomyelitis
Demyelinating Diseases
encephalitis
Stem cells

Transfer of myelin-reactive Th17 cells impairs endogenous remyelination in the central nervous system of cuprizone-fed mice

Baxi, E. G., DeBruin, J., Tosi, D. M., Grishkan, I. V., Smith, M. D., Kirby, L. A., Strasburger, H. J., Fairchild, A. N., Calabresi, P. & Gocke, A. R., Jun 3 2015, In : Journal of Neuroscience. 35, 22, p. 8626-8639 14 p.

Research output: Contribution to journalArticle

Cuprizone
Th17 Cells
Myelin Sheath
Central Nervous System
Animal Models
2014

A selective thyroid hormone β receptor agonist enhances human and rodent oligodendrocyte differentiation

Baxi, E. G., Schott, J. T., Fairchild, A. N., Kirby, L. A., Karani, R., Uapinyoying, P., Pardo-Villamizar, C. A., Rothstein, J. D., Bergles, D. E. & Calabresi, P., 2014, In : GLIA. 62, 9, p. 1513-1529 17 p.

Research output: Contribution to journalArticle

Thyroid Hormone Receptors
Oligodendroglia
Rodentia
Hormones
Thyroid Gland
2012

Functional blockade of the voltage-gated potassium channel Kv1.3 mediates reversion of T effector to central memory lymphocytes through SMAD3/p21 cip1 signaling

Hu, L., Gocke, A. R., Knapp, E., Rosenzweig, J. M., Grishkan, I. V., Baxi, E. G., Zhang, H., Margolick, J. B., Whartenby, K. & Calabresi, P., Jan 6 2012, In : Journal of Biological Chemistry. 287, 2, p. 1261-1268 8 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Lymphocytes
Autoimmune Diseases
T-cells
T-Lymphocytes
2011

NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination

de Biase, L. M., Kang, S. H., Baxi, E. G., Fukaya, M., Pucak, M. L., Mishina, M., Calabresi, P. & Bergles, D. E., Aug 31 2011, In : Journal of Neuroscience. 31, 35, p. 12650-12662 13 p.

Research output: Contribution to journalArticle

Oligodendroglia
N-Methyl-D-Aspartate Receptors
AMPA Receptors
Synapses
Axons
2009
Minocycline
Metallothionein
Neurons
Brain
Microglia
2007

Metallothionein I and II attenuate the thalamic microglial response following traumatic axotomy in the immature brain

Baxi, E. G., Cheng, Y., Knight, J. B., Gordish-Dressman, H. & Natale, J. E., Jan 2007, In : Journal of Neurotrauma. 24, 1, p. 28-42 15 p.

Research output: Contribution to journalArticle

Axotomy
Metallothionein
Microglia
Brain
Wounds and Injuries

Stem cells and neurologic diseases: Hope or hype?

Baxi, E. G., Cardona, M. & Kerr, D., Sep 2007, In : Future Neurology. 2, 5, p. 471-475 5 p.

Research output: Contribution to journalArticle

Nervous System Diseases
Stem Cells