Elizabeth Thompson

Assistant Professor

20082020

Research output per year

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Research Output

2020

Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas

Felsenstein, M., Trujillo, M. A., Huang, B., Nanda, N., Jiang, Z., Jeong, Y. J., Pflüger, M., Goggins, M. G., Hruban, R. H., Thompson, E. D., Heaphy, C. M., Roberts, N. J. & Wood, L. D., Jan 1 2020, (Accepted/In press) In : Laboratory Investigation.

Research output: Contribution to journalArticle

Pan-tumor pathologic scoring of response to PD-(L)1 blockade

Stein, J. E., Lipson, E. J., Cottrell, T. R., Forde, P. M., Anders, R. A., Cimino-Mathews, A., Thompson, E. D., Allaf, M. E., Yarchoan, M., Feliciano, J., Wang, H., Jaffee, E. M., Pardoll, D. M., Topalian, S. L. & Taube, J. M., Feb 1 2020, In : Clinical Cancer Research. 26, 3, p. 545-551 7 p.

Research output: Contribution to journalReview article

2019

A multimodality test to guide the management of patients with a pancreatic cyst

Springer, S., Masica, D. L., Molin, M. D., Douville, C., Thoburn, C. J., Afsari, B., Li, L., Cohen, J. D., Thompson, E., Allen, P. J., Klimstra, D. S., Schattner, M. A., Max Schmidt, C., Yip-Schneider, M., Simpson, R. E., Castillo, C. F. D., Mino-Kenudson, M., Brugge, W., Brand, R. E., Singhi, A. D. & 40 others, Scarpa, A., Lawlor, R., Salvia, R., Zamboni, G., Hong, S. M., Hwang, D. W., Jang, J. Y., Kwon, W., Swan, N., Geoghegan, J., Falconi, M., Crippa, S., Doglioni, C., Paulino, J., Schulick, R. D., Edil, B. H., Park, W., Yachida, S., Hijioka, S., Van Hooft, J., He, J., Weiss, M. J., Burkhart, R., Makary, M., Canto, M. I., Goggins, M. G., Ptak, J., Dobbyn, L., Schaefer, J., Sillman, N., Popoli, M., Klein, A. P., Tomasetti, C., Karchin, R., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Wolfgang, C. L., Hruban, R. H. & Lennon, A. M., Jul 17 2019, In : Science translational medicine. 11, 501, eaav4772.

Research output: Contribution to journalArticle

A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer

Yarchoan, M., Huang, C. Y., Zhu, Q., Ferguson, A. K., Durham, J. N., Anders, R. A., Thompson, E. D., Rozich, N. S., Thomas, D. L., Nauroth, J. M., Rodriguez, C., Osipov, A., De Jesus-Acosta, A., Le, D. T., Murphy, A. G., Laheru, D., Donehower, R. C., Jaffee, E. M., Zheng, L. & Azad, N. S., Jan 1 2019, (Accepted/In press) In : Cancer medicine.

Research output: Contribution to journalArticle

Open Access

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice

Jurcak, N. R., Rucki, A. A., Muth, S., Thompson, E., Sharma, R., Ding, D., Zhu, Q., Eshleman, J., Anders, R. A., Jaffee, E., Fujiwara, K. & Zheng, L., Sep 1 2019, In : Gastroenterology. 157, 3, p. 838-850.e6

Research output: Contribution to journalArticle

Biphenotypic Differentiation of Pancreatic Cancer in 3-Dimensional Culture

Matsushita, Y., Smith, B., Delannoy, M., Trujillo, M. A., Chianchiano, P., McMillan, R., Kamiyama, H., Liang, H., Thompson, E. D., Hruban, R. H., Matsui, W., Wood, L. D., Roberts, N. J. & Eshleman, J. R., Oct 1 2019, In : Pancreas. 48, 9, p. 1225-1231 7 p.

Research output: Contribution to journalArticle

Challenges in Diagnosis and Management of Pancreatic Inflammatory Myofibroblastic Tumors in Children

Berhe, S., Goldstein, S., Thompson, E., Hackam, D., Rhee, D. & Nasr, I., Apr 1 2019, In : Pancreas. 48, 4, p. E27-E29

Research output: Contribution to journalLetter

Cross Validation of the Monoclonal Antibody Das-1 in Identification of High-Risk Mucinous Pancreatic Cystic Lesions

Das, K. K., Geng, X., Brown, J. W., Morales-Oyarvide, V., Huynh, T., Pergolini, I., Pitman, M. B., Ferrone, C., Al Efishat, M., Haviland, D., Thompson, E., Wolfgang, C., O'Broin-Lennon, A. M., Allen, P., Lillemoe, K. D., Fields, R. C., Hawkins, W. G., Liu, J., Castillo, C. F. D., Das, K. M. & 1 others, Mino-Kenudson, M., Sep 1 2019, In : Gastroenterology. 157, 3, p. 720-730.e2

Research output: Contribution to journalArticle

Feasibility of Using Hydrogel Spacers for Borderline-Resectable and Locally Advanced Pancreatic Tumors

Kerdsirichairat, T., Narang, A. K., Thompson, E., Kim, S. H., Rao, A., Ding, K. & Shin, E. J., Oct 1 2019, In : Gastroenterology. 157, 4, p. 933-935 3 p.

Research output: Contribution to journalArticle

Immunopathologic stratification of colorectal cancer for checkpoint blockade immunotherapy

Llosa, N. J., Luber, B., Siegel, N., Awan, A. H., Oke, T., Zhu, Q., Bartlett, B. R., Aulakh, L. K., Thompson, E. D., Jaffee, E. M., Durham, J. N., Sears, C. L., Le, D. T., Diaz, L. A., Pardoll, D. M., Wang, H., Housseau, F. & Anders, R. A., Jan 1 2019, In : Cancer Immunology Research. 7, 10, p. 1574-1579 6 p.

Research output: Contribution to journalArticle

Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations

Fischer, C. G., Beleva Guthrie, V., Braxton, A. M., Zheng, L., Wang, P., Song, Q., Griffin, J. F., Chianchiano, P. E., Hosoda, W., Niknafs, N., Springer, S., Dal Molin, M., Masica, D., Scharpf, R. B., Thompson, E. D., He, J., Wolfgang, C. L., Hruban, R. H., Roberts, N. J., Lennon, A. M. & 3 others, Jiao, Y., Karchin, R. & Wood, L. D., Oct 1 2019, In : Gastroenterology. 157, 4, p. 1123-1137.e22

Research output: Contribution to journalArticle

Intratumoral adaptive immunosuppression and type 17 immunity in mismatch repair proficient colorectal tumors

Llosa, N. J., Luber, B., Tam, A. J., Smith, K. N., Siegel, N., Awan, A. H., Fan, H., Oke, T., Zhang, J., Domingue, J., Engle, E. L., Roberts, C. A., Bartlett, B. R., Aulakh, L. K., Thompson, E. D., Taube, J. M., Durham, J. N., Sears, C. L., Le, D. T., Diaz, L. A. & 4 others, Pardoll, D. M., Wang, H., Anders, R. A. & Housseau, F., Sep 1 2019, In : Clinical Cancer Research. 25, 17, p. 5250-5259 10 p.

Research output: Contribution to journalArticle

Open Access

Mucocele Presenting as Polypoid Bronchoscopic Lesion with Post-Obstructive Pneumonia

Shafiq, M., Thompson, E., Illei, P. & Yarmus, L., Jan 1 2019, (Accepted/In press) In : Lung.

Research output: Contribution to journalComment/debate

Pancreatic Nerve Sheath Tumors: a Single Institutional Series and Systematic Review of the Literature

Javed, A. A., Wright, M. J., Hasanain, A., Chang, K., Burkhart, R., Hruban, R. H., Thompson, E., Fishman, E. K., Cameron, J. L., He, J., Wolfgang, C. & Weiss, M. J., Jan 1 2019, In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Smith, K. N., Llosa, N. J., Cottrell, T. R., Siegel, N., Fan, H., Suri, P., Chan, H. Y., Guo, H., Oke, T., Awan, A. H., Verde, F., Danilova, L., Anagnostou, V., Tam, A. J., Luber, B. S., Bartlett, B. R., Aulakh, L. K., Sidhom, J. W., Zhu, Q., Sears, C. L. & 21 others, Cope, L., Sharfman, W. H., Thompson, E. D., Riemer, J., Marrone, K. A., Naidoo, J., Velculescu, V. E., Forde, P. M., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., Durham, J. N., Wang, H., Le, D. T., Justesen, S., Taube, J. M., Diaz, L. A., Brahmer, J. R., Pardoll, D. M., Anders, R. A. & Housseau, F., Feb 11 2019, In : Journal for immunotherapy of cancer. 7, 1, 40.

Research output: Contribution to journalArticle

Open Access

Prevalence of Germline Mutations Associated With Cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms

Skaro, M., Nanda, N., Gauthier, C., Felsenstein, M., Jiang, Z., Qiu, M., Shindo, K., Yu, J., Hutchings, D., Javed, A. A., Beckman, R., He, J., Wolfgang, C., Thompson, E., Hruban, R. H., Klein, A., Goggins, M. S., Wood, L. D. & Roberts, N., May 1 2019, In : Gastroenterology. 156, 6, p. 1905-1913 9 p.

Research output: Contribution to journalArticle

Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions

Kuboki, Y., Fischer, C. G., Beleva Guthrie, V., Huang, W., Yu, J., Chianchiano, P., Hosoda, W., Zhang, H., Zheng, L., Shao, X., Thompson, E. D., Waters, K., Poling, J., He, J., Weiss, M. J., Wolfgang, C. L., Goggins, M. G., Hruban, R. H., Roberts, N. J., Karchin, R. & 1 others, Wood, L. D., Jan 1 2019, (Accepted/In press) In : Journal of Pathology.

Research output: Contribution to journalArticle

Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion

Hong, S. M., Jung, D. J., Kiemen, A., Gaida, M. M., Yoshizawa, T., Braxton, A. M., Noë, M., Lionheart, G., Oshima, K., Thompson, E. D., Burkhart, R., Wu, P. H., Wirtz, D., Hruban, R. H. & Wood, L. D., Jan 1 2019, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Why is pancreatic cancer so deadly? The pathologist's view

Hruban, R. H., Gaida, M. M., Thompson, E., Hong, S. M., Noë, M., Brosens, L. A. A., Jongepier, M., Offerhaus, G. J. A. & Wood, L. D., Jan 1 2019, In : Journal of Pathology.

Research output: Contribution to journalArticle

2018

A "clearer" View of Pancreatic Pathology: A Review of Tissue Clearing and Advanced Microscopy Techniques

Hong, S. M., Noë, M., Hruban, C. A., Thompson, E., Wood, L. D. & Hruban, R. H., Jan 1 2018, (Accepted/In press) In : Advances in Anatomic Pathology.

Research output: Contribution to journalArticle

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D., Froeling, F. E. M., Burkhart, R., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., Lacomb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. C., Johnson, M., Arora, K. & 50 others, Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., Dimaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O’kane, G. M., Notta, F., Kim, E., Crawford, J. M., Devoe, C., Ocean, A., Wolfgang, C., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R., Knox, J., Krasnitz, A., Gallinger, S. & Tuveson, D. A., Sep 1 2018, In : Cancer Discovery. 8, 9, p. 1112-1129 18 p.

Research output: Contribution to journalArticle

Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: A proposal for quantitative immune-related pathologic response criteria (irPRC)

Cottrell, T. R., Thompson, E., Forde, P., Stein, J. E., Duffield, A. S., Anagnostou, V., Rekhtman, N., Anders, R. A., Cuda, J. D., Illei, P. B., Gabrielson, E., Askin, F. B., Niknafs, N., Smith, K., Velez, M. J., Sauter, J. L., Isbell, J. M., Jones, D. R., Battafarano, R. J., Yang, S. C. & 10 others, Danilova, L. V., Wolchok, J. D., Topalian, S., Velculescu, V. E., Pardoll, A. M., Brahmer, J., Hellmann, M. D., Chaft, J. E., Cimino-Mathews, A. M. & Taube, J. M., Jan 1 2018, In : Annals of Oncology. 29, 8, p. 1853-1860 8 p.

Research output: Contribution to journalArticle

2017

PD-L1 expression and the immune microenvironment in primary invasive lobular carcinomas of the breast

Thompson, E., Taube, J. M., Asch-Kendrick, R. J., Ogurtsova, A., Xu, H., Sharma, R., Meeker, A. K., Argani, P., Emens, L. A. & Cimino-Mathews, A. M., Nov 1 2017, In : Modern Pathology. 30, 11, p. 1551-1560 10 p.

Research output: Contribution to journalArticle

Safety & clinical activity of the programmed death-ligand 1 inhibitor durvalumab in combination with Poly (ADP-Ribose) polymerase inhibitor olaparib or vascular endothelial growth factor Receptor 1-3 Inhibitor Cediranib in Women's Cancers: A dose-escalation, phase I study

Lee, J. M., Cimino-Mathews, A. M., Peer, C. J., Zimmer, A., Lipkowitz, S., Annunziata, C. M., Cao, L., Harrell, M. I., Swisher, E. M., Houston, N., Botesteanu, D. A., Taube, J. M., Thompson, E., Ogurtsova, A., Xu, H., Nguyen, J., Ho, T. W., Figg, W. D. & Kohn, E. C., Jul 1 2017, In : Journal of Clinical Oncology. 35, 19, p. 2193-2202 10 p.

Research output: Contribution to journalArticle

2016

Erratum: Using quantitative seroproteomics to identify antibody biomarkers in pancreatic cancer (Cancer Immunology Research (2016) 4 (225-233))

Jhaveri, D. T., Kim, M. S., Thompson, E. D., Huang, L., Sharma, R. & Klein, A. P., May 1 2016, In : Cancer immunology research. 4, 5, p. 472 1 p.

Research output: Contribution to journalComment/debate

Large cell neuroendocrine Carcinoma of the head and neck: A clinicopathologic series of 10 cases with an emphasis on HPV status

Thompson, E., Stelow, E. B., Mills, S. E., Westra, W. H. & Bishop, J. A., 2016, In : American Journal of Surgical Pathology. 40, 4, p. 471-478 8 p.

Research output: Contribution to journalArticle

Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma

Thompson, E., Zahurak, M., Murphy, A., Cornish, T., Cuka, N., Abdelfatah, E., Yang, S. C., Duncan, M. D., Ahuja, N., Taube, J. M., Anders, R. A. & Kelly, R. J., Jan 22 2016, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas

Cimino-Mathews, A. M., Thompson, E., Taube, J. M., Ye, X., Lu, Y., Meeker, A. K., Xu, H., Sharma, R., Lecksell, K., Cornish, T. C., Cuka, N., Argani, P. & Emens, L. A., Jan 1 2016, In : Human Pathology. 47, 1, p. 52-63 12 p.

Research output: Contribution to journalArticle

The immune microenvironment of breast ductal carcinoma in situ

Thompson, E., Taube, J. M., Elwood, H., Sharma, R., Meeker, A. K., Warzecha, H. N., Argani, P., Cimino-Mathews, A. M. & Emens, L. A., Mar 1 2016, In : Modern Pathology. 29, 3, p. 249-258 10 p.

Research output: Contribution to journalArticle

Using quantitative seroproteomics to identify antibody biomarkers in pancreatic cancer

Jhaveri, D. T., Kim, M. S., Thompson, E., Huang, L., Sharma, R., Klein, A., Zheng, L., Le, D., Laheru, D., Pandey, A., Jaffee, E. & Anders, R. A., Mar 1 2016, In : Cancer immunology research. 4, 3, p. 225-233 9 p.

Research output: Contribution to journalArticle

2015

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity

Peske, J. D., Thompson, E., Gemta, L., Baylis, R. A., Fu, Y. X. & Engelhard, V. H., May 13 2015, In : Nature Communications. 6, 7114.

Research output: Contribution to journalArticle

2010

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

Thompson, E., Enriquez, H. L., Fu, Y. X. & Engelhard, V. H., Aug 2 2010, In : Journal of Experimental Medicine. 207, 8, p. 1791-1804 14 p.

Research output: Contribution to journalArticle

2008

Strategies and challenges in eliciting immunity to melanoma

Ferguson, A. R., Nichols, L. A., Zarling, A. L., Thompson, E., Brinkman, C. C., Hargadon, K. M., Bullock, T. N. & Engelhard, V. H., Apr 2008, In : Immunological Reviews. 222, 1, p. 28-42 15 p.

Research output: Contribution to journalReview article