Research Output 1992 2018

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2018

Histopathological and immunophenotypic features of ipilimumab-associated colitis compared to ulcerative colitis

Adler, B. L., Pezhouh, M. K., Kim, A., Luan, L., Zhu, Q., Gani, F., Yarchoan, M., Chen, J., Voltaggio, L., Parian, A., Lazarev, M., Lauwers, G. Y., Pawlik, T. M., Montgomery, E. A., Jaffee, E., Le, D. T., Taube, J. M. & Anders, R. A. Jan 1 2018 (Accepted/In press) In : Journal of Internal Medicine.

Research output: Contribution to journalArticle

Colitis
Ulcerative Colitis
ipilimumab
Biopsy
Inflammatory Bowel Diseases

Immune modulation therapy and imaging: Workshop report

Shields, A. F., Jacobs, P. M., Sznol, M., Graham, M. M., Germain, R. N., Lum, L. G., Jaffee, E. M., De Vries, E. G. E., Nimmagadda, S., Van Den Abbeele, A. D., Leung, D. K., Wu, A. M., Sharon, E. & Shankar, L. K. Mar 1 2018 In : Journal of Nuclear Medicine. 59, 3, p. 410-417 8 p.

Research output: Contribution to journalArticle

Immunotherapy
Education
Therapeutics
Immunoglobulin Fragments
Tumor Microenvironment
2017

A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice

Foote, J. B., Kok, M., Leatherman, J. M., Armstrong, T. D., Marcinkowski, B. C., Ojalvo, L. S., Kanne, D. B., Jaffee, E. M., Dubensky, T. W. & Emens, L. A. Jun 1 2017 In : Cancer Immunology Research. 5, 6, p. 468-479 12 p.

Research output: Contribution to journalArticle

OX40 Receptor
Interferons
Immunity
T-Lymphocytes
Growth

Characterization of the immune microenvironment in hepatocellular carcinoma

Yarchoan, M., Xing, D., Luan, L., Xu, H., Sharma, R. B., Popovic, A., Pawlik, T. M., Kim, A. K., Zhu, Q., Jaffee, E. M., Taube, J. M. & Anders, R. A. Dec 1 2017 In : Clinical Cancer Research. 23, 23, p. 7333-7339 7 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
Liver
CD8-Positive T-Lymphocytes
Tumor-Infiltrating Lymphocytes

Dual inhibition of Hedgehog and c-Met pathways for pancreatic cancer treatment

Rucki, A. A., Xiao, Q., Muth, S., Chen, J., Che, X., Kleponis, J., Sharma, R., Anders, R. A., Jaffee, E. M. & Zheng, L. Nov 1 2017 In : Molecular Cancer Therapeutics. 16, 11, p. 2399-2409 11 p.

Research output: Contribution to journalArticle

Hedgehogs
Pancreatic Neoplasms
Adenocarcinoma
gemcitabine
Tumor Burden

Hedgehog signaling stimulates Tenascin C to promote invasion of pancreatic ductal adenocarcinoma cells through Annexin A2

Foley, K., Muth, S., Jaffee, E. & Zheng, L. Feb 4 2017 (Accepted/In press) In : Cell Adhesion and Migration. p. 1-10 10 p.

Research output: Contribution to journalArticle

Annexins
Tenascin
Adenocarcinoma
Stromal Cells
Neoplasms

Heterogeneous stromal signaling within the tumor microenvironment controls the metastasis of pancreatic cancer

Rucki, A. A., Foley, K., Zhang, P., Xiao, Q., Kleponis, J., Wu, A. A., Sharma, R., Mo, G., Liu, A., Van Eyk, J., Jaffee, E. M. & Zheng, L. Jan 1 2017 In : Cancer Research. 77, 1, p. 41-52 12 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Pancreatic Neoplasms
Adenocarcinoma
Neoplasm Metastasis
Insulin-Like Growth Factor I

Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy

Rao, A. D. , Liu, Y. , von Eyben, R. , Hsu, C. C. , Hu, C. , Rosati, L. M. , Parekh, A. , Ng, K. , Hacker-Prietz, A. , Zheng, L. , Pawlik, T. M. , Laheru, D. A. , Jaffee, E. M. , Weiss, M. J. , Le, D. T. , Hruban, R. H. , De Jesus-Acosta, A. , Wolfgang, C. L. , Narang, A. K. , Chang, D. T. & 2 others Koong, A. C. & Herman, J. M. Jan 1 2017 (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

biomarkers
Pancreatic Neoplasms
Ligation
proximity
radiation therapy

Olaparib in combination with irinotecan, cisplatin, and mitomycin c in patients with advanced pancreatic cancer

Yarchoan, M., Myzak, M. C., Johnson, B. A., De Jesus-Acosta, A. D., Le, D. T., Jaffee, E. M., Azad, N. S., Donehower, R. C., Zheng, L., Oberstein, P. E., Fine, R. L., Laheru, D. A. & Goggins, M. 2017 In : Oncotarget. 8, 27, p. 44073-44081 9 p.

Research output: Contribution to journalArticle

irinotecan
Mitomycin
Pancreatic Neoplasms
Cisplatin
Adenocarcinoma

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T. , Kumar, S. , Borkar, R. N. , Azimi, V. , Thibault, G. , Chang, Y. H. , Balter, A. , Kawashima, R. , Choe, G. , Sauer, D. , El Rassi, E. , Clayburgh, D. R. , Kulesz-Martin, M. F. , Lutz, E. R. , Zheng, L. , Jaffee, E. M. , Leyshock, P. , Margolin, A. A. , Mori, M. , Gray, J. W. & 2 others Flint, P. W. & Coussens, L. M. Apr 4 2017 In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

Tumors
Immunohistochemistry
Tissue
T-cells
Biomarkers

Report on the third FDA–AACR oncology dose-finding workshop

Emens, L. A., Bruno, R., Rubin, E. H., Jaffee, E. M. & McKee, A. E. Dec 1 2017 In : Cancer Immunology Research. 5, 12, p. 1058-1061 4 p.

Research output: Contribution to journalArticle

Education
Practice Guidelines
Patient Selection
Biomarkers
Therapeutics

Stereotactic Body Radiation Therapy for Isolated Local Recurrence After Surgical Resection of Pancreatic Ductal Adenocarcinoma Appears to be Safe and Effective

Ryan, J. F., Groot, V. P., Rosati, L. M., Hacker-Prietz, A., Narang, A. K., McNutt, T. R., Jackson, J. F., Le, D. T., Jaffee, E. M., Zheng, L., Laheru, D. A., He, J., Pawlik, T. M., Weiss, M. J., Wolfgang, C. L. & Herman, J. M. Oct 23 2017 (Accepted/In press) In : Annals of Surgical Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Radiotherapy
Recurrence
Maintenance Chemotherapy
Disease-Free Survival

Stromal Annexin A2 expression is predictive of decreased survival in pancreatic cancer

Murphy, A. G., Foley, K., Rucki, A. A., Xia, T., Jaffee, E. M., Huang, C. Y. & Zheng, L. Jan 1 2017 In : Oncotarget. 8, 63, p. 106405-106414 10 p.

Research output: Contribution to journalArticle

Annexin A2
Annexins
Pancreatic Neoplasms
Adenocarcinoma
Survival

Workshop on challenges, insights, and future directions for mouse and humanized models in cancer immunology and immunotherapy: A report from the associated programs of the 2016 annual meeting for the Society for Immunotherapy of cancer

Zloza, A., Karolina Palucka, A., Coussens, L. M., Gotwals, P. J., Headley, M. B., Jaffee, E. M., Lund, A. W., Sharpe, A. H., Sznol, M., Wainwright, D. A., Wong, K. K. & Bosenberg, M. W. Sep 19 2017 In : Journal for ImmunoTherapy of Cancer. 5, 1, 77

Research output: Contribution to journalArticle

Allergy and Immunology
Immunotherapy
Education
Neoplasms
Direction compound
2016

Cancer-associated fibroblasts in pancreatic cancer are reprogrammed by tumor-induced alterations in genomic DNA methylation

Xiao, Q., Zhou, D., Rucki, A. A., Williams, J., Zhou, J., Mo, G., Murphy, A., Fujiwara, K., Kleponis, J., Salman, B., Wolfgang, C. L., Anders, R. A., Zheng, S., Jaffee, E. M. & Zheng, L. Sep 15 2016 In : Cancer Research. 76, 18, p. 5395-5404 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Pancreatic Neoplasms
Adenocarcinoma
Methylation
Neoplasms

De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation

Ladle, B. H., Li, K. P., Phillips, M. J., Pucsek, A. B., Haile, A., Powell, J. D., Jaffee, E. M., Hildeman, D. A. & Gamper, C. J. Sep 20 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 38, p. 10631-10636 6 p.

Research output: Contribution to journalArticle

DNA Methylation
T-Lymphocytes
Wild Animals
DNA methyltransferase 3A
Methyltransferases

Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma

Lee, D., Lyu, H., Chung, Y. H., Kim, J. A., Mathews, P., Jaffee, E., Zheng, L., Yu, E., Lee, Y. J. & Ryu, S. H. Jun 21 2016 In : World Journal of Gastroenterology. 22, 23, p. 5393-5399 7 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Mutation
Genotype
Chronic Hepatitis B

Leveraging premalignant biology for immune-based cancer prevention

Spira, A., Disis, M. L., Schiller, J. T., Vilar, E., Rebbeck, T. R., Bejar, R., Ideker, T., Arts, J., Yurgelun, M. B., Mesirov, J. P., Rao, A., Garber, J., Jaffee, E. M. & Lippman, S. M. Sep 27 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. 10750-10758 9 p.

Research output: Contribution to journalArticle

Neoplasms
Genetic Phenomena
Immune Evasion
Hereditary Nonpolyposis Colorectal Neoplasms
Cancer Vaccines

Lymphocyte-Sparing Effect of Stereotactic Body Radiation Therapy in Patients with Unresectable Pancreatic Cancer

Wild, A. T., Herman, J. M., Dholakia, A. S., Moningi, S., Lu, Y., Rosati, L. M., Hacker-Prietz, A., Assadi, R. K., Saeed, A. M., Pawlik, T. M., Jaffee, E. M., Laheru, D. A., Tran, P. T., Weiss, M. J., Wolfgang, C. L., Ford, E., Grossman, S. A., Ye, X. & Ellsworth, S. G. 2016 In : International Journal of Radiation Oncology, Biology, Physics. 94, 3, p. 571-579 9 p.

Research output: Contribution to journalArticle

lymphocytes
Pancreatic Neoplasms
radiation therapy
Radiotherapy
cancer

Mesothelin immunotherapy for cancer: Ready for prime time?

Hassan, R., Thomas, A., Alewine, C., Le, D. T., Jaffee, E. M. & Pastan, I. Dec 1 2016 In : Journal of Clinical Oncology. 34, 34, p. 4171-4179 9 p.

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
Cell- and Tissue-Based Therapy
Antibodies
Phase II Clinical Trials

Using quantitative seroproteomics to identify antibody biomarkers in pancreatic cancer

Jhaveri, D. T., Kim, M. S., Thompson, E. D., Huang, L., Sharma, R., Klein, A. P., Zheng, L., Le, D. T., Laheru, D. A., Pandey, A., Jaffee, E. M. & Anders, R. A. Mar 1 2016 In : Cancer immunology research. 4, 3, p. 225-233 9 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Biomarkers
Immunoprecipitation
Antibodies
Cancer Vaccines
2015

Current progress in immunotherapy for pancreatic cancer

Foley, K., Kim, V., Jaffee, E. & Zheng, L. 2015 (Accepted/In press) In : Cancer Letters.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Immunotherapy
Vaccines
T-Lymphocytes
Tumor Microenvironment

Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival

De Remigis, A., De Gruijl, T. D., Uram, J. N., Tzou, S. C., Iwama, S., Talor, M. V., Armstrong, T. D., Santegoets, S. J. A. M., Slovin, S. F., Zheng, L., Laheru, D. A., Jaffee, E. M., Gerritsen, W. R., Van Den Eertwegh, A. J. M., Le, D. T. & Caturegli, P. Jan 1 2015 In : International Journal of Cancer. 136, 1, p. 127-137 11 p.

Research output: Contribution to journalArticle

Thyroglobulin
Immunotherapy
Survival
Antibodies
Epitopes

Galectin-3 shapes antitumor immune responses by suppressing CD8 T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells

Kouo, T., Huang, L., Pucsek, A. B., Cao, M., Solt, S., Armstrong, T. & Jaffee, E. Apr 1 2015 In : Cancer immunology research. 3, 4, p. 412-423 12 p.

Research output: Contribution to journalArticle

Galectin 3
Dendritic Cells
T-Lymphocytes
T-Cell Antigen Receptor
Adenocarcinoma

Immune therapy in GI malignancies: A review

Wang, J., Reiss, K. A., Khatri, R., Jaffee, E. & Laheru, D. Jun 1 2015 In : Journal of Clinical Oncology. 33, 16, p. 1745-1753 9 p.

Research output: Contribution to journalArticle

Neoplasms
Immunotherapy
Therapeutics
Oncogenes
Immune System
Vaccines
Antigens
Neoplasms
Early Detection of Cancer
Carcinogenesis

PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors

Soares, K. C., Rucki, A. A., Wu, A. A., Olino, K., Xiao, Q., Chai, Y., Wamwea, A., Bigelow, E., Lutz, E., Liu, L., Yao, S., Anders, R. A., Laheru, D., Wolfgang, C. L., Edil, B. H., Schulick, R. D., Jaffee, E. M. & Zheng, L. Jan 14 2015 In : Journal of Immunotherapy. 38, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Active Immunotherapy
Adenocarcinoma
T-Lymphocytes
CTLA-4 Antigen
Neoplasms

Safety and survival with GVAX pancreas prime and Listeria monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer

Le, D. T. , Wang-Gillam, A. , Picozzi, V. , Greten, T. F. , Crocenzi, T. , Springett, G. , Morse, M. , Zeh, H. , Cohen, D. , Fine, R. L. , Onners, B. , Uram, J. N. , Laheru, D. A. , Lutz, E. R. , Solt, S. , Murphy, A. L. , Skoble, J. , Lemmens, E. , Grous, J. , Dubensky, T. & 2 others Brockstedt, D. G. & Jaffee, E. M. Apr 20 2015 In : Journal of Clinical Oncology. 33, 12, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

Listeria monocytogenes
Pancreatic Neoplasms
Cyclophosphamide
Pancreas
Vaccines

Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer

Foley, K., Rucki, A. A., Xiao, Q., Zhou, D., Leubner, A., Mo, G., Kleponis, J., Wu, A. A., Sharma, R., Jiang, Q., Anders, R. A., Iacobuzio-Donahue, C. A., Hajjar, K. A., Maitra, A., Jaffee, E. M. & Zheng, L. Aug 4 2015 In : Science Signaling. 8, 388, ra77

Research output: Contribution to journalArticle

Autocrine Communication
Semaphorins
Annexins
Annexin A2
Pancreatic Neoplasms

Special conference on tumor immunology and immunotherapy: A new chapter

Byrne, K. T., Vonderheide, R. H., Jaffee, E. M. & Armstrong, T. D. Jun 1 2015 In : Cancer immunology research. 3, 6, p. 590-597 8 p.

Research output: Contribution to journalArticle

Allergy and Immunology
Immunotherapy
Neoplasms
Tumor Microenvironment
Therapeutics

TGF-β blockade depletes T regulatory cells from metastatic pancreatic tumors in a vaccine dependent manner

Soares, K. C., Rucki, A. A., Kim, V., Foley, K., Solt, S., Wolfgang, C. L., Jaffee, E. M. & Zheng, L. 2015 In : Oncotarget. 6, 40, p. 43005-43015 11 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Transforming Growth Factor beta
Vaccines
Neoplasms
Adenocarcinoma

The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy

Bever, K. M., Sugar, E. A., Bigelow, E., Sharma, R., Laheru, D., Wolfgang, C. L., Jaffee, E. M., Anders, R. A., De Jesus-Acosta, A. & Zheng, L. Apr 1 2015 In : HPB. 17, 4, p. 292-298 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Adenocarcinoma
Pancreatic Stellate Cells
Tissue Preservation
Therapeutics
2014

A feasibility study of cyclophosphamide, trastuzumab, and an allogeneic GM-CSF-secreting breast tumor vaccine for HER2+ metastatic breast cancer

Chen, G. , Gupta, R. , Petrik, S. , Laiko, M. , Leatherman, J. M. , Asquith, J. M. , Daphtary, M. M. , Garrett-Mayer, E. , Davidson, N. E. , Hirt, K. , Berg, M. , Uram, J. N. , Dauses, T. , Fetting, J. , Duus, E. M. , Atay-Rosenthal, S. , Ye, X. , Wolff, A. C. , Stearns, V. , Jaffee, E. M. & 1 others Emens, L. A. Oct 1 2014 In : Cancer immunology research. 2, 10, p. 949-961 13 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Feasibility Studies
Granulocyte-Macrophage Colony-Stimulating Factor
Cyclophosphamide
Vaccination

A listeria vaccine and depletion of t-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice

Keenan, B. P., Saenger, Y., Kafrouni, M. I., Leubner, A., Lauer, P., Maitra, A., Rucki, A. A., Gunderson, A. J., Coussens, L. M., Brockstedt, D. G., Dubensky, T. W., Hassan, R., Armstrong, T. D. & Jaffee, E. M. 2014 In : Gastroenterology. 146, 7

Research output: Contribution to journalArticle

Listeria
Carcinoma in Situ
Pancreatic Neoplasms
Immunity
Vaccines
Apoptosis
T-Lymphocytes
Neoplasms
Clonal Deletion
Cell Death

A preclinical murine model of hepatic metastases

Soares, K. C., Foley, K., Olino, K., Leubner, A., Mayo, S. C., Jain, A., Schulick, R. D., Jaffee, E., Yoshimura, K., Edil, B. & Zheng, L. Sep 27 2014 In : Journal of Visualized Experiments. 91, e51677

Research output: Contribution to journalArticle

Tumors
Neoplasm Metastasis
Liver
Immunology
Neoplasms
Cancer Vaccines
Feasibility Studies
Granulocyte-Macrophage Colony-Stimulating Factor
Colonic Neoplasms
Colorectal Neoplasms

Cancer immunoprevention - The next frontier

Smit, M. A. D., Jaffee, E. M. & Lutz, E. R. Nov 1 2014 In : Cancer Prevention Research. 7, 11, p. 1072-1080 9 p.

Research output: Contribution to journalArticle

Neoplasms
Immune Tolerance
Recurrence
Steam
Residual Neoplasm

Fusion protein of mutant B7-DC and Fc enhances the antitumor immune effect of GM-CSF-secreting whole-cell vaccine

Kojima, M., Murata, S., Mekata, E., Takebayashi, K., Jaffee, E. M. & Tani, T. 2014 In : Journal of Immunotherapy. 37, 3, p. 147-154 8 p.

Research output: Contribution to journalArticle

Mutant Proteins
Granulocyte-Macrophage Colony-Stimulating Factor
Dendritic Cells
Vaccines
Death Domain Receptors

Immunobiology of radiotherapy: New paradigms

Ahmed, M. M., Guha, C., Hodge, J. W. & Jaffee, E. 2014 In : Radiation Research. 182, 2, p. 123-125 3 p.

Research output: Contribution to journalArticle

neoplasms
Combined Modality Therapy
Antigen Presentation
Myeloid Cells
Immunotherapy

Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation

Lutz, E. R., Wu, A. A., Bigelow, E., Sharma, R., Mo, G., Soares, K., Solt, S., Dorman, A., Wamwea, A., Yager, A., Laheru, D., Wolfgang, C. L., Wang, J., Hruban, R. H., Anders, R. A., Jaffee, E. M. & Zheng, L. Jul 1 2014 In : Cancer immunology research. 2, 7, p. 616-631 16 p.

Research output: Contribution to journalArticle

Immunotherapy
Tumor Microenvironment
Adenocarcinoma
Vaccines
T-Lymphocytes

Oncogenic kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia

McAllister, F., Bailey, J. M., Alsina, J., Nirschl, C. J., Sharma, R., Fan, H., Rattigan, Y., Roeser, J. C., Lankapalli, R. H., Zhang, H., Jaffee, E. M., Drake, C. G., Housseau, F., Maitra, A., Kolls, J. K., Sears, C. L., Pardoll, D. M. & Leach, S. D. May 12 2014 In : Cancer Cell. 25, 5, p. 621-637 17 p.

Research output: Contribution to journalArticle

Interleukin-17
Neoplasms
Interleukin-17 Receptors
Chronic Pancreatitis
Epithelial Cells

PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition

Zhou, W. , Jubb, A. M. , Lyle, K. , Xiao, Q. , Ong, C. C. , Desai, R. , Fu, L. , Gnad, F. , Song, Q. , Haverty, P. M. , Aust, D. , Grützmann, R. , Romero, M. , Totpal, K. , Neve, R. M. , Yan, Y. , Forrest, W. F. , Wang, Y. , Raja, R. , Pilarsky, C. & 8 others De Jesus-Acosta, A., Belvin, M., Friedman, L. S., Merchant, M., Jaffee, E. M., Zheng, L., Koeppen, H. & Hoeflich, K. P. Dec 1 2014 In : Journal of Pathology. 234, 4, p. 502-513 12 p.

Research output: Contribution to journalArticle

p21-Activated Kinases
Pancreatic Neoplasms
Cell Movement
Proto-Oncogene Proteins c-met
Adenocarcinoma

Priming the pancreatic cancer tumor microenvironment for checkpoint-inhibitor immunotherapy

Lutz, E. R., Kinkead, H., Jaffee, E. M. & Zheng, L. Nov 2 2014 In : OncoImmunology. 3, 11, p. e962401-1-e962401-3

Research output: Contribution to journalArticle

Tumor Microenvironment
Pancreatic Neoplasms
Immunotherapy
Neoplasms
Allergy and Immunology

Specificity delivers: Therapeutic role of tumor antigen-specific antibodies in pancreatic cancer

Jhaveri, D. T., Zheng, L. & Jaffee, E. M. Oct 1 2014 In : Seminars in Oncology. 41, 5, p. 559-575 17 p.

Research output: Contribution to journalArticle

Neoplasm Antigens
Pancreatic Neoplasms
Adenocarcinoma
Antibodies
Biomarkers
2013

Effects of genomic changes in hepatitis B virus on postoperative recurrence and survival in patients with hepatocellular carcinoma

Mathews, P., Lee, D., Chung, Y. H., Kim, J. A., Lee, J. H., Jin, Y. J., Park, W., Lyu, H., Jaffee, E., Zheng, L., Yu, E. & Lee, Y. J. Apr 2013 In : Annals of Surgical Oncology. 20, 4, p. 1216-1222 7 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Recurrence
Survival
Neoplasms
Granulocyte-Macrophage Colony-Stimulating Factor
Pancreatic Neoplasms
Genes
Neoplasms
CTLA-4 Antigen

Harnessing immune responses in the tumor microenvironment: All signals needed

Le, D. T. & Jaffee, E. M. Nov 15 2013 In : Clinical Cancer Research. 19, 22, p. 6061-6063 3 p.

Research output: Contribution to journalArticle

gemcitabine
Tumor Microenvironment
Immunotherapy
Adenocarcinoma
B-Lymphocytes

Immunohistochemical staining of B7-H1 (PD-L1) on paraffin-embedded slides of pancreatic adenocarcinoma tissue.

Bigelow, E., Bever, K. M., Xu, H., Yager, A., Wu, A., Taube, J., Chen, L., Jaffee, E. M., Anders, R. A. & Zheng, L. 2013 In : Journal of Visualized Experiments. 71

Research output: Contribution to journalArticle

Paraffin
Paraffins
Tumors
Adenocarcinoma
Tissue
Immunotherapy
Tumors
Vaccines
Neoplasms
Cancer Vaccines