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Elizabeth Jaffee

Professor

1992 …2019
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  • 3 Similar Profiles
Neoplasms Medicine & Life Sciences
Cancer Vaccines Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Granulocyte-Macrophage Colony-Stimulating Factor Medicine & Life Sciences

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Research Output 1992 2019

A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell–Mediated Anticancer Activity

Ma, H. S., Poudel, B., Torres, E. R., Sidhom, J. W., Robinson, T., Christmas, B., Scott, B., Cruz, K., Woolman, S., Wall, V. Z., Armstrong, T. D. & Jaffee, E., Mar 1 2019, In : Cancer Immunology Research. 7, 3, p. 428-442 15 p.

Research output: Contribution to journal › Article

Tumor Microenvironment
Antibodies
Monoclonal Antibodies
T-Lymphocytes
Tumor-Infiltrating Lymphocytes

Anti–CTLA-4 synergizes with dendritic cell–targeted vaccine to promote IL-3–dependent CD4 + effector T cell infiltration into murine pancreatic tumors

Zaidi, N., Quezada, S. A., Kuroiwa, J. M. Y., Zhang, L., Jaffee, E., Steinman, R. M. & Wang, B., Jan 1 2019, In : Annals of the New York Academy of Sciences.

Research output: Contribution to journal › Article

T-cells
Interleukin-3
Infiltration
Tumors
Vaccines

Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies

Kim, V. M., Blair, A. B., Lauer, P., Foley, K., Che, X., Soares, K., Xia, T., Muth, S. T., Kleponis, J., Armstrong, T. D., Wolfgang, C., Jaffee, E., Brockstedt, D. & Zheng, L., May 22 2019, In : Journal for immunotherapy of cancer. 7, 1, 132.

Research output: Contribution to journal › Article

Open Access
Annexin A2
Annexins
Listeria
Immunotherapy
Adenocarcinoma

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice

Jurcak, N. R., Rucki, A. A., Muth, S., Thompson, E., Sharma, R., Ding, D., Zhu, Q., Eshleman, J., Anders, R. A., Jaffee, E., Fujiwara, K. & Zheng, L., Sep 1 2019, In : Gastroenterology. 157, 3, p. 838-850.e6

Research output: Contribution to journal › Article

Adenocarcinoma
Neoplasm Metastasis
Neoplasms
Spinal Ganglia
Annexin A2

Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts

Elyada, E., Bolisetty, M., Laise, P., Flynn, W. F., Courtois, E. T., Burkhart, R., Teinor, J. A., Belleau, P., Biffi, G., Lucito, M. S., Sivajothi, S., Armstrong, T. D., Engle, D. D., Yu, K. H., Hao, Y., Wolfgang, C., Park, Y., Preall, J., Jaffee, E., Califano, A. & 2 others, Robson, P. & Tuveson, D. A., Aug 1 2019, In : Cancer discovery. 9, 8, p. 1102-1123 22 p.

Research output: Contribution to journal › Review article

Open Access
Single-Cell Analysis
Adenocarcinoma
Antigens
Population
RNA Sequence Analysis