Elias Zambidis

Associate Professor

19962018

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2018
2017

Altered Differentiation Potential of Gaucher's Disease iPSC Neuronal Progenitors due to Wnt/β-Catenin Downregulation

Awad, O., Panicker, L. M., Deranieh, R. M., Srikanth, M. P., Brown, R. A., Voit, A., Peesay, T., Park, T. S., Zambidis, E. & Feldman, R. A., Dec 12 2017, In : Stem Cell Reports. 9, 6, p. 1853-1867 15 p.

Research output: Contribution to journalArticle

2016

Enrichment of Scleroderma Vascular Disease–Associated Autoantigens in Endothelial Lineage Cells

McMahan, Z., Cottrell, T. R., Wigley, F., Antiochos, B., Zambidis, E., Park, T. S., Halushka, M. K., Gutierrez, L., Cimbro, R., Rosen, A. & Casciola Rosen, L. A., Oct 1 2016, In : Arthritis and Rheumatology. 68, 10, p. 2540-2549 10 p.

Research output: Contribution to journalArticle

High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional Signature

Nagaria, P. K., Robert, C., Park, T. S., Huo, J., Zambidis, E. & Rassool, F. V., 2016, In : Stem Cells International. 2016, 3826249.

Research output: Contribution to journalArticle

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

Salomonis, N., Dexheimer, P. J., Omberg, L., Schroll, R., Bush, S., Huo, J., Schriml, L., Ho Sui, S., Keddache, M., Mayhew, C., Shanmukhappa, S. K., Wells, J., Daily, K., Hubler, S., Wang, Y., Zambidis, E., Margolin, A., Hide, W., Hatzopoulos, A. K., Malik, P. & 3 others, Cancelas, J. A., Aronow, B. J. & Lutzko, C., Jul 12 2016, In : Stem Cell Reports. 7, 1, p. 110-125 16 p.

Research output: Contribution to journalArticle

Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality

Zimmerlin, L., Park, T. S., Huo, J., Verma, K., Pather, S. R., Talbot, C. C., Agarwal, J., Steppan, D., Zhang, Y., Considine, M., Guo, H., Zhong, X., Gutierrez, C., Cope, L., Canto-Soler, M. V., Friedman, A. D., Baylin, S. B. & Zambidis, E., Dec 1 2016, In : Development (Cambridge). 143, 23, p. 4368-4380 13 p.

Research output: Contribution to journalArticle

Variability of Action Potentials Within and among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells

Zhu, R., Millrod, M. A., Zambidis, E. & Tung, L., Jan 5 2016, In : Scientific Reports. 6, 18544.

Research output: Contribution to journalArticle

2015

Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells: Efficient Generation of Genetically Engineered Germ Cells

Bazley, F. A., Liu, C. F., Yuan, X., Hao, H., All, A. H., De Los Angeles, A., Zambidis, E., Gearhart, J. D. & Kerr, C. L., Nov 15 2015, In : Stem Cells and Development. 24, 22, p. 2634-2648 15 p.

Research output: Contribution to journalArticle

Gaucher disease-induced pluripotent stem cells display decreased erythroid potential and aberrant myelopoiesis

Sgambato, J. A., Park, T. S., Miller, D., Panicker, L. M., Sidransky, E., Lun, Y., Awad, O., Bentzen, S. M., Zambidis, E. T. & Feldman, R. A., Jul 27 2015, In : Stem Cells Translational Medicine. 4, 8, p. 878-886 9 p.

Research output: Contribution to journalArticle

2014

Automated grouping of action potentials of human embryonic stem cell-derived cardiomyocytes

Gorospe, G., Zhu, R., Millrod, M. A., Zambidis, E., Tung, L. & Vidal, R., 2014, In : IEEE Transactions on Biomedical Engineering. 61, 9, p. 2389-2395 7 p., 6766211.

Research output: Contribution to journalArticle

Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development

Panicker, L. M., Miller, D., Awad, O., Bose, V., Lun, Y., Park, T. S., Zambidis, E., Sgambato, J. A. & Feldman, R. A., 2014, In : Stem Cells. 32, 9, p. 2338-2349 12 p.

Research output: Contribution to journalArticle

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

Zhong, X., Gutierrez, C., Xue, T., Hampton, C., Vergara, M. N., Cao, L. H., Peters, A., Park, T. S., Zambidis, E., Meyer, J. S., Gamm, D. M., Yau, K-W. & Canto-Soler, M. V., Jun 10 2014, In : Nature Communications. 5, 4047.

Research output: Contribution to journalArticle

Induced pluripotent stem cells from familial alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties

Machairaki, V., Ryu, J., Peters, A., Chang, Q., Li, T., Park, T. S., Burridge, P. W., Talbot, C. C., Asnaghi, L., Martin, L. J., Zambidis, E. & Koliatsos, V. E., Dec 15 2014, In : Stem Cells and Development. 23, 24, p. 2996-3010 15 p.

Research output: Contribution to journalArticle

Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature

Park, T. S., Bhutto, I., Zimmerlin, L., Huo, J., Nagaria, P., Miller, D., Rufaihah, A. J., Talbot, C., Aguilar, J., Grebe, R., Merges, C., Reijo-Pera, R., Feldman, R. A., Rassool, F., Cooke, J., Lutty, G. A. & Zambidis, E., Jan 21 2014, In : Circulation. 129, 3, p. 359-372 14 p.

Research output: Contribution to journalArticle

2013

Efficient and simultaneous generation of hematopoietic and vascular progenitors from human induced pluripotent stem cells

Park, T. S., Zimmerlin, L. & Zambidis, E., Jan 2013, In : Cytometry Part A. 83 A, 1, p. 114-126 13 p.

Research output: Contribution to journalArticle

Human induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneity

Rufaihah, A. J., Huang, N. F., Kim, J., Herold, J., Volz, K. S., Park, T. S., Lee, J. C., Zambidis, E., Reijo-Pera, R. & Cooke, J. P., 2013, In : American Journal of Translational Research. 5, 1, p. 21-35 15 p.

Research output: Contribution to journalArticle

Mesenchymal stem cell secretome and regenerative therapy after cancer

Zimmerlin, L., Park, T. S., Zambidis, E., Donnenberg, V. S. & Donnenberg, A. D., Dec 2013, In : Biochimie. 95, 12, p. 2235-2245 11 p.

Research output: Contribution to journalArticle

2012

Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility

Blazeski, A., Zhu, R., Hunter, D. W., Weinberg, S. H., Zambidis, E. & Tung, L., Oct 2012, In : Progress in Biophysics and Molecular Biology. 110, 2-3, p. 166-177 12 p.

Research output: Contribution to journalArticle

Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells

Blazeski, A., Zhu, R., Hunter, D. W., Weinberg, S. H., Boheler, K. R., Zambidis, E. & Tung, L., Oct 2012, In : Progress in Biophysics and Molecular Biology. 110, 2-3, p. 178-195 18 p.

Research output: Contribution to journalArticle

Engraftment of human embryonic stem cell derived cardiomyocytes improves conduction in an arrhythmogenic in vitro model

Thompson, S. A., Burridge, P. W., Lipke, E. A., Shamblott, M., Zambidis, E. & Tung, L., Jul 2012, In : Journal of Molecular and Cellular Cardiology. 53, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Growth factor-activated stem cell circuits and stromal signals cooperatively accelerate non-integrated iPSC reprogramming of human myeloid progenitors

Park, T. S., Huo, J., Peters, A., Talbot, C. C., Verma, K., Zimmerlin, L., Kaplan, I. M. & Zambidis, E., Aug 8 2012, In : PLoS One. 7, 8, e42838.

Research output: Contribution to journalArticle

HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

Shah, S. N., Kerr, C., Cope, L., Zambidis, E., Liu, C., Hillion, J., Belton, A., Huso, D. L. & Smith Resar, L. M., Nov 15 2012, In : PLoS One. 7, 11, e48533.

Research output: Contribution to journalArticle

Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease

Panicker, L. M., Miller, D., Park, T. S., Patel, B., Azevedo, J. L., Awad, O., Masood, M. A., Veenstra, T. D., Goldin, E., Stubblefield, B. K., Tayebi, N., Polumuri, S. K., Vogel, S. N., Sidransky, E., Zambidis, E. & Feldman, R. A., Oct 30 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 44, p. 18054-18059 6 p.

Research output: Contribution to journalArticle

2011

A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

Burridge, P. W., Thompson, S., Millrod, M. A., Weinberg, S., Yuan, X., Peters, A., Machairaki, V., Koliatsos, V. E., Tung, L. & Zambidis, E., 2011, In : PLoS One. 6, 4, e18293.

Research output: Contribution to journalArticle

2010

Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells

Ohm, J. E., Mali, P., Van Neste, L., Berman, D. M., Liang, L., Pandiyan, K., Briggs, K. J., Zhang, W., Argani, P., Simons, B., Yu, W., Matsui, W., Van Criekinge, W., Rassool, F. V., Zambidis, E., Schuebel, K., Cope, L., Yen, J., Mohammad, H. P., Cheng, L. & 1 others, Baylin, S. B., Oct 1 2010, In : Cancer Research. 70, 19, p. 7662-7673 12 p.

Research output: Contribution to journalArticle

Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells

Peters, A., Burridge, P. W., Pryzhkova, M., Levine, M. A., Park, T. S., Roxbury, C., Yuan, X., Bruno, P. & Zambidis, E., 2010, In : International Journal of Developmental Biology. 54, 6-7, p. 965-990 26 p.

Research output: Contribution to journalArticle

2009

Human embryonic stem cell-derived hematoendothelial progenitors engraft chicken embryos

Park, T. S., Zambidis, E., Lucitti, J. L., Logar, A., Keller, B. B. & Péault, B., Jan 2009, In : Experimental Hematology. 37, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

2008

Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells

Zambidis, E., Park, T. S., Yu, W., Tam, A., Levine, M., Yuan, X., Pryzhkova, M. & Péault, B., Nov 1 2008, In : Blood. 112, 9, p. 3601-3614 14 p.

Research output: Contribution to journalArticle

2006

Blood-forming endothelium in human ontogeny: Lessons from in utero development and embryonic stem cell culture

Zambidis, E., Oberlin, E., Tavian, M. & Péault, B., Apr 2006, In : Trends in Cardiovascular Medicine. 16, 3, p. 95-101 7 p.

Research output: Contribution to journalArticle

2005

Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development

Zambidis, E., Peault, B., Park, T. S., Bunz, F. & Civin, C. I., Aug 1 2005, In : Blood. 106, 3, p. 860-870 11 p.

Research output: Contribution to journalArticle

2004

Malignant peritoneal mesothelioma in a pediatric patient mimicking inflammatory bowel disease

Oberto, C., Schwarz, K., Zambidis, E., Campbell, A. B., Paidas, C., Lindyberg, K. & Oliva-Hemker, M., Mar 2004, In : Digestive Diseases and Sciences. 49, 3, p. 434-437 4 p.

Research output: Contribution to journalArticle

2000

Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis

Agarwal, R. K., Kang, Y., Zambidis, E., Scott, D. W., Chan, C. C. & Caspi, R. R., Jul 2000, In : Journal of Clinical Investigation. 106, 2, p. 245-252 8 p.

Research output: Contribution to journalArticle

1998

Mechanisms of gene therapy for tolerance

Melo, M. E. F., Zambidis, E. & Scott, D. W., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

1997
1996

Epitope-specific tolerance induction with an engineered immunoglobulin

Zambidis, E. T. & Scott, D. W., May 14 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 10, p. 5019-5024 6 p.

Research output: Contribution to journalArticle