Elias Zambidis

Associate Professor

19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina

Park, T. S., Zimmerlin, L., Evans-Moses, R., Thomas, J., Huo, J. S., Kanherkar, R., He, A., Ruzgar, N., Grebe, R., Bhutto, I., Barbato, M., Koldobskiy, M. A., Lutty, G. & Zambidis, E. T., Dec 1 2020, In : Nature communications. 11, 1, 1195.

Research output: Contribution to journalArticle

Open Access
2018

Infant with a skin lesion and respiratory distress

Cuviello, A., Rice, J., Cohen, B. A. & Zambidis, E., Jan 1 2018, In : BMJ Case Reports. 2018, 224506.

Research output: Contribution to journalComment/debate

2017

Altered Differentiation Potential of Gaucher's Disease iPSC Neuronal Progenitors due to Wnt/β-Catenin Downregulation

Awad, O., Panicker, L. M., Deranieh, R. M., Srikanth, M. P., Brown, R. A., Voit, A., Peesay, T., Park, T. S., Zambidis, E. & Feldman, R. A., Dec 12 2017, In : Stem Cell Reports. 9, 6, p. 1853-1867 15 p.

Research output: Contribution to journalArticle

Capturing Human Naïve Pluripotency in the Embryo and in the Dish

Zimmerlin, L., Park, T. S. & Zambidis, E., Aug 15 2017, In : Stem Cells and Development. 26, 16, p. 1141-1161 21 p.

Research output: Contribution to journalReview article

2016

Enrichment of Scleroderma Vascular Disease–Associated Autoantigens in Endothelial Lineage Cells

McMahan, Z., Cottrell, T. R., Wigley, F., Antiochos, B., Zambidis, E., Park, T. S., Halushka, M. K., Gutierrez, L., Cimbro, R., Rosen, A. & Casciola Rosen, L. A., Oct 1 2016, In : Arthritis and Rheumatology. 68, 10, p. 2540-2549 10 p.

Research output: Contribution to journalArticle

High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional Signature

Nagaria, P. K., Robert, C., Park, T. S., Huo, J., Zambidis, E. & Rassool, F. V., 2016, In : Stem Cells International. 2016, 3826249.

Research output: Contribution to journalArticle

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

Salomonis, N., Dexheimer, P. J., Omberg, L., Schroll, R., Bush, S., Huo, J., Schriml, L., Ho Sui, S., Keddache, M., Mayhew, C., Shanmukhappa, S. K., Wells, J., Daily, K., Hubler, S., Wang, Y., Zambidis, E., Margolin, A., Hide, W., Hatzopoulos, A. K., Malik, P. & 3 others, Cancelas, J. A., Aronow, B. J. & Lutzko, C., Jul 12 2016, In : Stem Cell Reports. 7, 1, p. 110-125 16 p.

Research output: Contribution to journalArticle

Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality

Zimmerlin, L., Park, T. S., Huo, J., Verma, K., Pather, S. R., Talbot, C. C., Agarwal, J., Steppan, D., Zhang, Y., Considine, M., Guo, H., Zhong, X., Gutierrez, C., Cope, L., Canto-Soler, M. V., Friedman, A. D., Baylin, S. B. & Zambidis, E., Dec 1 2016, In : Development (Cambridge). 143, 23, p. 4368-4380 13 p.

Research output: Contribution to journalArticle

Variability of Action Potentials Within and among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells

Zhu, R., Millrod, M. A., Zambidis, E. T. & Tung, L., Jan 5 2016, In : Scientific reports. 6, 18544.

Research output: Contribution to journalArticle

2015

Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells: Efficient Generation of Genetically Engineered Germ Cells

Bazley, F. A., Liu, C. F., Yuan, X., Hao, H., All, A. H., De Los Angeles, A., Zambidis, E. T., Gearhart, J. D. & Kerr, C. L., Nov 15 2015, In : Stem Cells and Development. 24, 22, p. 2634-2648 15 p.

Research output: Contribution to journalArticle

Gaucher disease-induced pluripotent stem cells display decreased erythroid potential and aberrant myelopoiesis

Sgambato, J. A., Park, T. S., Miller, D., Panicker, L. M., Sidransky, E., Lun, Y., Awad, O., Bentzen, S. M., Zambidis, E. T. & Feldman, R. A., Jul 27 2015, In : Stem Cells Translational Medicine. 4, 8, p. 878-886 9 p.

Research output: Contribution to journalArticle

2014

Automated grouping of action potentials of human embryonic stem cell-derived cardiomyocytes

Gorospe, G., Zhu, R., Millrod, M. A., Zambidis, E. T., Tung, L. & Vidal, R., Sep 2014, In : IEEE Transactions on Biomedical Engineering. 61, 9, p. 2389-2395 7 p., 6766211.

Research output: Contribution to journalArticle

Dynamic Interactions Between Cancer Stem Cells and Their Stromal Partners

Park, T. S., Donnenberg, V. S., Donnenberg, A. D., Zambidis, E. T. & Zimmerlin, L., Mar 1 2014, In : Current Pathobiology Reports. 2, 1, p. 41-52 12 p.

Research output: Contribution to journalReview article

Open Access

Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development

Panicker, L. M., Miller, D., Awad, O., Bose, V., Lun, Y., Park, T. S., Zambidis, E. T., Sgambato, J. A. & Feldman, R. A., Sep 2014, In : Stem Cells. 32, 9, p. 2338-2349 12 p.

Research output: Contribution to journalArticle

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

Zhong, X., Gutierrez, C., Xue, T., Hampton, C., Vergara, M. N., Cao, L. H., Peters, A., Park, T. S., Zambidis, E. T., Meyer, J. S., Gamm, D. M., Yau, K. W. & Canto-Soler, M. V., Jun 10 2014, In : Nature communications. 5, 4047.

Research output: Contribution to journalArticle

Induced pluripotent stem cells from familial alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties

Mahairaki, V., Ryu, J., Peters, A., Chang, Q., Li, T., Park, T. S., Burridge, P. W., Talbot, C. C., Asnaghi, L., Martin, L. J., Zambidis, E. T. & Koliatsos, V. E., Dec 15 2014, In : Stem Cells and Development. 23, 24, p. 2996-3010 15 p.

Research output: Contribution to journalArticle

Pericytes: A ubiquitous source of multipotent adult tissue stem cells

Zimmerlin, L., Park, T. S., Donnenberg, V. S., Zambidis, E. T. & Donnenberg, A. D., Nov 1 2014, Stem Cells in Aesthetic Procedures: Art, Science, and Clinical Techniques. Springer-Verlag Berlin Heidelberg, Vol. 9783642452079. p. 135-148 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature

Park, T. S., Bhutto, I., Zimmerlin, L., Huo, J. S., Nagaria, P., Miller, D., Rufaihah, A. J., Talbot, C., Aguilar, J., Grebe, R., Merges, C., Reijo-Pera, R., Feldman, R. A., Rassool, F., Cooke, J., Lutty, G. & Zambidis, E. T., Jan 21 2014, In : Circulation. 129, 3, p. 359-372 14 p.

Research output: Contribution to journalArticle

2013

Efficient and simultaneous generation of hematopoietic and vascular progenitors from human induced pluripotent stem cells

Park, T. S., Zimmerlin, L. & Zambidis, E. T., Jan 1 2013, In : Cytometry Part A. 83 A, 1, p. 114-126 13 p.

Research output: Contribution to journalArticle

Highly efficient directed differentiation of human induced pluripotent stem cells into cardiomyocytes

Burridge, P. W. & Zambidis, E. T., May 8 2013, Pluripotent Stem Cells: Methods and Protocols. Lakshmipathy, U. & Vemuri, M. (eds.). p. 149-161 13 p. (Methods in Molecular Biology; vol. 997).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Human induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneity

Rufaihah, A. J., Huang, N. F., Kim, J., Herold, J., Volz, K. S., Park, T. S., Lee, J. C., Zambidis, E. T., Reijo-Pera, R. & Cooke, J. P., Jan 1 2013, In : American Journal of Translational Research. 5, 1, p. 21-35 15 p.

Research output: Contribution to journalArticle

Mesenchymal stem cell secretome and regenerative therapy after cancer

Zimmerlin, L., Park, T. S., Zambidis, E. T., Donnenberg, V. S. & Donnenberg, A. D., Dec 2013, In : Biochimie. 95, 12, p. 2235-2245 11 p.

Research output: Contribution to journalShort survey

2012

Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility

Blazeski, A., Zhu, R., Hunter, D. W., Weinberg, S. H., Zambidis, E. T. & Tung, L., Oct 1 2012, In : Progress in Biophysics and Molecular Biology. 110, 2-3, p. 166-177 12 p.

Research output: Contribution to journalReview article

Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells

Blazeski, A., Zhu, R., Hunter, D. W., Weinberg, S. H., Boheler, K. R., Zambidis, E. T. & Tung, L., Oct 1 2012, In : Progress in Biophysics and Molecular Biology. 110, 2-3, p. 178-195 18 p.

Research output: Contribution to journalReview article

Engraftment of human embryonic stem cell derived cardiomyocytes improves conduction in an arrhythmogenic in vitro model

Thompson, S. A., Burridge, P. W., Lipke, E. A., Shamblott, M., Zambidis, E. T. & Tung, L., Jul 1 2012, In : Journal of Molecular and Cellular Cardiology. 53, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Growth factor-activated stem cell circuits and stromal signals cooperatively accelerate non-integrated iPSC reprogramming of human myeloid progenitors

Park, T. S., Huo, J. S., Peters, A., Talbot, C. C., Verma, K., Zimmerlin, L., Kaplan, I. M. & Zambidis, E. T., Aug 8 2012, In : PloS one. 7, 8, e42838.

Research output: Contribution to journalArticle

HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

Shah, S. N., Kerr, C., Cope, L., Zambidis, E., Liu, C., Hillion, J., Belton, A., Huso, D. L. & Resar, L. M. S., Nov 15 2012, In : PloS one. 7, 11, e48533.

Research output: Contribution to journalArticle

Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease

Panicker, L. M., Miller, D., Park, T. S., Patel, B., Azevedo, J. L., Awad, O., Masood, M. A., Veenstra, T. D., Goldin, E., Stubblefield, B. K., Tayebi, N., Polumuri, S. K., Vogel, S. N., Sidransky, E., Zambidis, E. T. & Feldman, R. A., Oct 30 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 44, p. 18054-18059 6 p.

Research output: Contribution to journalArticle

2011

A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

Burridge, P. W., Thompson, S., Millrod, M. A., Weinberg, S., Yuan, X., Peters, A., Mahairaki, V., Koliatsos, V. E., Tung, L. & Zambidis, E. T., Apr 20 2011, In : PloS one. 6, 4, e18293.

Research output: Contribution to journalArticle

2010

Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells

Ohm, J. E., Mali, P., Van Neste, L., Berman, D. M., Liang, L., Pandiyan, K., Briggs, K. J., Zhang, W., Argani, P., Simons, B., Yu, W., Matsui, W., Van Criekinge, W., Rassool, F. V., Zambidis, E., Schuebel, K. E., Cope, L., Yen, J., Mohammad, H. P., Cheng, L. & 1 others, Baylin, S. B., Oct 1 2010, In : Cancer Research. 70, 19, p. 7662-7673 12 p.

Research output: Contribution to journalArticle

Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells

Peters, A., Burridge, P. W., Pryzhkova, M. V., Levine, M. A., Soon Park, T., Roxbury, C., Yuan, X., Bruno, P. & Zambidis, E. T., Jul 28 2010, In : International Journal of Developmental Biology. 54, 6-7, p. 965-990 26 p.

Research output: Contribution to journalReview article

2009

A role for the renin-angiotensin system in hematopoiesis

Park, T. S. & Zambidis, E. T., Jun 1 2009, In : Haematologica. 94, 6, p. 745-747 3 p.

Research output: Contribution to journalEditorial

Human embryonic stem cell-derived hematoendothelial progenitors engraft chicken embryos

Park, T. S., Zambidis, E. T., Lucitti, J. L., Logar, A., Keller, B. B. & Péault, B., Jan 1 2009, In : Experimental Hematology. 37, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

2008

Blood vessels as a source of progenitor cells in human embryonic and adult life

Crisan, M., Zheng, B., Zambidis, E., Yap, S., Tavian, M., Sun, B., Giacobino, J. P., Casteilla, L., Huard, J. & Péault, B., Dec 1 2008, Stem Cells and their Potential for Clinical Application. Bilko, N. (ed.). p. 137-147 11 p. (NATO Security through Science Series C: Environmental Security).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells

Zambidis, E. T., Park, T. S., Yu, W., Tam, A., Levine, M., Yuan, X., Pryzhkova, M. & Péault, B., Nov 1 2008, In : Blood. 112, 9, p. 3601-3614 14 p.

Research output: Contribution to journalArticle

2007

Emergence of human angiohematopoietic cells in normal development and from cultured embryonic stem cells

Zambidis, E. T., Sinka, L., Tavian, M., Jokubaitis, V., Tea, S. P., Simmons, P. & Péault, B., Jun 2007, Hematopoietic Stem Cells VI. Blackwell Publishing Inc., p. 223-232 10 p. (Annals of the New York Academy of Sciences; vol. 1106).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2006

Blood-forming endothelium in human ontogeny: Lessons from in utero development and embryonic stem cell culture

Zambidis, E. T., Oberlin, E., Tavian, M. & Péault, B., Apr 1 2006, In : Trends in Cardiovascular Medicine. 16, 3, p. 95-101 7 p.

Research output: Contribution to journalReview article

Blood vessels as a source of progenitor cells in human embryonic and adult life

Crisan, M., Zheng, B., Zambidis, E., Yap, S., Tavian, M., Sun, B., Giacobino, J. P., Casteilla, L., Huard, J. & Péault, B., Dec 1 2006, Stem Cells and their Potential for Clinical Application. p. 137-147 11 p. (NATO Security through Science Series B: Physics and Biophysics).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2005
2004

Malignant peritoneal mesothelioma in a pediatric patient mimicking inflammatory bowel disease

Oberto, C., Schwarz, K. B., Zambidis, E., Campbell, A. B., Paidas, C., Lindyberg, K. & Oliva-Hemker, M., Mar 1 2004, In : Digestive diseases and sciences. 49, 3, p. 434-437 4 p.

Research output: Contribution to journalArticle