Elena MacFarlane

Assistant Professor

20022019

Research output per year

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Research Output

Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis

Kim, D. H., Beckett, J. D., Nagpal, V., Seman-Senderos, M. A., Gould, R. A., Creamer, T. J., MacFarlane, E., Chen, Y., Bedja, D., Butcher, J. T., Mitzner, W. A., Rouf, R., Hata, S., Warren, D. & Dietz, H. C., Jul 17 2019, In : Science translational medicine. 11, 501, eaau2814.

Research output: Contribution to journalArticle

  • Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis

    Shin, J. Y., Beckett, J. D., Bagirzadeh, R., Creamer, T. J., Shah, A. A., McMahan, Z., Paik, J. J., Sampedro, M. M., MacFarlane, E. G., Beer, M. A., Warren, D., Wigley, F. M. & Dietz, H. C., Jan 1 2019, In : Science translational medicine. 11, 497, eaaw0790.

    Research output: Contribution to journalArticle

  • Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome

    MacFarlane, E., Parker, S. J., Shin, J. Y., Ziegler, S. G., Creamer, T. J., Bagirzadeh, R., Bedja, D., Chen, Y., Calderon, J. F., Weissler, K., Frischmeyer-Guerrerio, P. A., Lindsay, M. E., Habashi, J. & Dietz, H. C., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 659-675 17 p.

    Research output: Contribution to journalArticle

  • Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome

    Habashi, J., MacFarlane, E., Bagirzadeh, R., Bowen, C., Huso, N., Chen, Y., Bedja, D., Creamer, T. J., Rykiel, G., Manning, M., Huso, D. & Dietz, H. C., May 1 2019, In : Science translational medicine. 11, 490

    Research output: Contribution to journalArticle

  • Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation

    van der Pluijm, I., Burger, J., van Heijningen, P. M., IJpma, A., van Vliet, N., Milanese, C., Schoonderwoerd, K., Sluiter, W., Ringuette, L. J., Dekkers, D. H. W., Que, I., Kaijzel, E. L., Te Riet, L., MacFarlane, E., Das, D., van der Linden, R., Vermeij, M., Demmers, J. A., Mastroberardino, P. G., Davis, E. C. & 4 others, Yanagisawa, H., Dietz, H. C., Kanaar, R. & Essers, J., Nov 1 2018, In : Cardiovascular Research. 114, 13, p. 1776-1793 18 p.

    Research output: Contribution to journalArticle