Elana Fertig

Associate Professor

20062019
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Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Methylation Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Genome Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
Tumors Chemical Compounds

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Research Output 2006 2019

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E -Induced Tumorigenesis

Tao, Y., Kang, B., Petkovich, D. A., Bhandari, Y. R., In, J., Stein-O'Brien, G., Kong, X., Xie, W., Zachos, N., Maegawa, S., Vaidya, H., Brown, S., Yen, R-W., Shao, X., Thakor, J., Lu, Z., Cai, Y., Zhang, Y., Mallona, I., Peinado, M. A. & 6 others, Zahnow, C., Ahuja, N., Fertig, E., Issa, J. P., Baylin, S. B. & Easwaran, H., Feb 11 2019, In : Cancer cell. 35, 2, p. 315-328.e6

Research output: Contribution to journalArticle

Epigenomics
Organoids
Colon
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats

A mechanism of resistance to antibody-targeted immune attack

Aldeghaither, D. S., Zahavi, D. J., Murray, J. C., Fertig, E., Graham, G. T., Zhang, Y. W., O'Connell, A., Ma, J., Jablonski, S. A. & Weiner, L. M., Feb 1 2019, In : Cancer immunology research. 7, 2, p. 230-243 14 p.

Research output: Contribution to journalArticle

Antibody-Dependent Cell Cytotoxicity
Antibodies
Epidermal Growth Factor Receptor
Synapses
Immune System

A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab

Espinosa-Cotton, M., Fertig, E., Stabile, L. P., Gaither-Davis, A., Bauman, J. E., Schmitz, S., Gibson-Corley, K. N., Cheng, Y., Jensen, I. J., Badovinac, V. P., Laux, D. & Simons, A. L., Jul 16 2019, In : Biomarker Research. 7, 1, 14.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Interleukin-1
Ligands
Chemotherapy
Genes

Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression

Hughes, R. M., Simons, B. W., Khan, H., Miller, R., Kugler, V., Torquato, S., Theodros, D., Haffner, M. C., Lotan, T., Huang, J., Davicioni, E., An, S., Riddle, R., Thorek, D. L. J., Garraway, I. P., Fertig, E., Isaacs, J. T., Nathaniel Brennen, W., Park, B. H. & Hurley, P., Jan 1 2019, In : Cancer Research. 79, 14, p. 3636-3650 15 p.

Research output: Contribution to journalArticle

Open Access
Tumor Microenvironment
Mesenchymal Stromal Cells
Cell Differentiation
Neoplasms
Neoplasm Metastasis

Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers

Ando, M., Saito, Y., Xu, G., Bui, N. Q., Medetgul-Ernar, K., Pu, M., Fisch, K., Ren, S., Sakai, A., Fukusumi, T., Liu, C., Haft, S., Pang, J., Mark, A., Gaykalova, D., Guo, T., Favorov, A., Yegnasubramanian, S., Fertig, E., Ha, P. & 5 others, Tamayo, P., Yamasoba, T., Ideker, T., Messer, K. & Califano, J. A., Dec 1 2019, In : Nature communications. 10, 1, 2188.

Research output: Contribution to journalArticle

Open Access
chromatin
methylation
Transcription Initiation Site
DNA Methylation
Chromatin