Edward Lakatta

Professor

1971 …2018
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Research Output 1971 2018

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

Tsutsui, K., Monfredi, O. J., Sirenko-Tagirova, S. G., Maltseva, L. A., Bychkov, R., Kim, M. S., Ziman, B. D., Tarasov, K. V., Tarasova, Y. S., Zhang, J., Wang, M., Maltsev, A. V., Brennan, J. A., Efimov, I. R., Stern, M. D., Maltsev, V. A. & Lakatta, E. G. Jun 12 2018 In : Science Signaling. 11, 534, eaap7608

Research output: Contribution to journalArticle

Action Potentials
Cyclic AMP-Dependent Protein Kinases
Sinoatrial Node
Membrane Potentials
Adrenergic Receptors
Sarcoplasmic Reticulum
Ion Channels
Ions
Rabbits
Calcium

Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials

Lyashkov, A. E., Beahr, J., Lakatta, E. G., Yaniv, Y. & Maltsev, V. A. Mar 13 2018 In : Biophysical Journal. 114, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Action Potentials
Membrane Potentials
Ryanodine Receptor Calcium Release Channel
Sarcoplasmic Reticulum
Noise

Reduced vasorin enhances angiotensin II signaling within the aging arterial wall

Pintus, G., Giordo, R., Wang, Y., Zhu, W., Kim, S. H., Zhang, L., Ni, L., Zhang, J., Telljohann, R., McGraw, K. R., Monticone, R. E., Ferris, C., Liu, L., Wang, M. & Lakatta, E. G. Jun 1 2018 In : Oncotarget. 9, 43, p. 27117-27132 16 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Angiotensin II
Smooth Muscle Myocytes
Matrix Metalloproteinases
Cell Wall