Douglas Gladstone

Associate Professor

19992020

Research output per year

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Research Output

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Article
2020

Haploidentical BMT for severe aplastic anemia with intensive GVHD prophylaxis including posttransplant cyclophosphamide

DeZern, A. E., Zahurak, M. L., Symons, H. J., Cooke, K. R., Rosner, G. L., Gladstone, D. E., Huff, C. A., Swinnen, L. J., Imus, P., Borrello, I., Wagner-Johnston, N., Ambinder, R. F., Luznik, L., Bolaños-Meade, J., Fuchs, E. J., Jones, R. J. & Brodsky, R. A., Apr 28 2020, In : Blood Advances. 4, 8, p. 1770-1779 10 p.

Research output: Contribution to journalArticle

Open Access
2019
Open Access
2018

Moxetumomab pasudotox in relapsed/refractory hairy cell leukemia

Kreitman, R. J., Dearden, C., Zinzani, P. L., Delgado, J., Karlin, L., Robak, T., Gladstone, D. E., le Coutre, P., Dietrich, S., Gotic, M., Larratt, L., Offner, F., Schiller, G., Swords, R., Bacon, L., Bocchia, M., Bouabdallah, K., Breems, D. A., Cortelezzi, A., Dinner, S. & 23 others, Doubek, M., Gjertsen, B. T., Gobbi, M., Hellmann, A., Lepretre, S., Maloisel, F., Ravandi, F., Rousselot, P., Rummel, M., Siddiqi, T., Tadmor, T., Troussard, X., Yi, C. A., Saglio, G., Roboz, G. J., Balic, K., Standifer, N., He, P., Marshall, S., Wilson, W., Pastan, I., Yao, N. S. & Giles, F., Aug 1 2018, In : Leukemia. 32, 8, p. 1768-1777 10 p.

Research output: Contribution to journalArticle

A phase 1 study of the PARP inhibitor veliparib in combination with temozolomide in acute myeloid leukemia

Gojo, I., Beumer, J. H., Pratz, K., McDevitt, M. A., Baer, M. R., Blackford, A. L., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M., Levis, M. J., Dezern, A., Gladstone, D., Ji, J. J., Wang, L., Kinders, R. J., Pouquet, M., Ali-Walbi, I., Rudek-Renaut, M., Poh, W. & 5 others, Herman, J. G., Karnitz, L. M., Kaufmann, S. H., Chen, A. & Karp, J., Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 697-706 10 p.

Research output: Contribution to journalArticle

A phase I study of topotecan, carboplatin and the PARP inhibitor veliparib in acute leukemias, aggressive myeloproliferative neoplasms, and chronic myelomonocytic leukemia

Pratz, K., Rudek-Renaut, M., Gojo, I., Litzow, M. R., McDevitt, M. A., Ji, J., Karnitz, L. M., Herman, J. G., Kinders, R. J., Smith, B. D., Gore, S. D., Carraway, H. E., Showel, M., Gladstone, D., Levis, M. J., Tsai, H. L., Rosner, G., Chen, A., Kaufmann, S. H. & Karp, J., Feb 15 2017, In : Clinical Cancer Research. 23, 4, p. 899-907 9 p.

Research output: Contribution to journalArticle

Change in IgHV Mutational Status of CLL Suggests Origin From Multiple Clones

Osman, A., Gocke, C. & Gladstone, D., Feb 1 2017, In : Clinical Lymphoma, Myeloma and Leukemia. 17, 2, p. 97-99 3 p.

Research output: Contribution to journalArticle

Low immunosuppressive burden after HLA-matched related or unrelated BMT using posttransplantation cyclophosphamide

Kanakry, C. G., Bolanos Meade, F. J., Kasamon, Y. L., Zahurak, M., Durakovic, N., Furlong, T., Mielcarek, M., Medeot, M., Gojo, I., Smith, B. D., Kanakry, J. A., Borrello, I. M., Brodsky, R. A., Gladstone, D., Huff, C. A., Matsui, W. H., Swinnen, L., Cooke, K. R., Ambinder, R. F., Fuchs, E. J. & 6 others, De Lima, M. J., Andersson, B. S., Varadhan, R., O'Donnell, P. V., Jones, R. J. & Luznik, L., Mar 9 2017, In : Blood. 129, 10, p. 1389-1393 5 p.

Research output: Contribution to journalArticle

Pharmacokinetically-targeted dosed everolimus maintenance therapy in lymphoma patients

Schoch, L. K., Asiama, A., Zahurak, M., Shanbhag, S. P., Hurtt, J., Sawyer, K., Swinnen, L., Wagner-Johnston, N., Jones, R. J., Ambinder, R. F. & Gladstone, D., Dec 13 2017, (Accepted/In press) In : Cancer Chemotherapy and Pharmacology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Open Access

Timed sequential therapy for acute myelogenous leukemia: Results of a retrospective study of 301 patients and review of the literature

Norsworthy, K. J., Dezern, A., Tsai, H. L., Hand, W. A., Varadhan, R., Gore, S. D., Gojo, I., Pratz, K., Carraway, H. E., Showel, M., McDevitt, M. A., Gladstone, D., Ghiaur, G., Prince, G., Seung, A. H., Benani, D., Levis, M. J., Karp, J. & Smith, B. D., Oct 1 2017, In : Leukemia Research. 61, p. 25-32 8 p.

Research output: Contribution to journalArticle

2016

Therapeutic drug monitoring for either oral or intravenous busulfan when combined with pre-and post-transplantation cyclophosphamide

Lombardi, L. R., Kanakry, C. G., Zahurak, M., Durakovic, N., Bolaños-Meade, J., Kasamon, Y. L., Gladstone, D. E., Matsui, W., Borrello, I., Huff, C. A., Swinnen, L. J., Brodsky, R. A., Ambinder, R. F., Fuchs, E. J., Rosner, G. L., Jones, R. J. & Luznik, L., Mar 3 2016, In : Leukemia and Lymphoma. 57, 3, p. 666-675 10 p.

Research output: Contribution to journalArticle

2015

A leukemic presentation of alveolar rhabdomyosarcoma in a 52-year-old woman without an identifiable primary tumor

Kern, J. B., Hii, A., Kruse, M. J., Szabo, Z., Argani, P., Hibbard, M. K., Gladstone, D. E., Meyer, C., Zheng, R., Borowitz, M. J. & Duffield, A. S., Feb 13 2015, In : International journal of surgical pathology. 23, 1, p. 75-77 3 p.

Research output: Contribution to journalArticle

Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

Campian, J. L., Ye, X., Gladstone, D. E., Ambady, P., Nirschl, T. R., Borrello, I., Golightly, M., King, K. E., Holdhoff, M., Karp, J., Drake, C. G. & Grossman, S. A., Sep 29 2015, In : Journal of neuro-oncology. 124, 2, p. 307-316 10 p.

Research output: Contribution to journalArticle

Risk-stratified outcomes of nonmyeloablative HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide

McCurdy, S. R., Kanakry, J. A., Showel, M. M., Tsai, H. L., Bolaños-Meade, J., Rosner, G. L., Kanakry, C. G., Perica, K., Symons, H. J., Brodsky, R. A., Gladstone, D. E., Huff, C. A., Pratz, K. W., Prince, G. T., Dezern, A. E., Gojo, I., Matsui, W. H., Borrello, I., McDevitt, M. A., Swinnen, L. J. & 7 others, Smith, B. D., Levis, M. J., Ambinder, R. F., Luznik, L., Jones, R. J., Fuchs, E. J. & Kasamon, Y. L., May 7 2015, In : Blood. 125, 19, p. 3024-3031 8 p.

Research output: Contribution to journalArticle

2014

Poly(ADP-ribose) polymerase inhibitor CEP-8983 synergizes with bendamustine in chronic lymphocytic leukemia cells in vitro

Dilley, R. L., Poh, W., Gladstone, D. E., Herman, J. G., Showel, M. M., Karp, J. E., McDevitt, M. A. & Pratz, K. W., Mar 1 2014, In : Leukemia Research. 38, 3, p. 411-417 7 p.

Research output: Contribution to journalArticle

2013

Brief intensive therapy for older adults with newly diagnosed Burkitt or atypical Burkitt lymphoma/leukemia

Kasamon, Y. L., Brodsky, R. A., Borowitz, M. J., Ambinder, R. F., Crilley, P. A., Cho, S. Y., Tsai, H. L., Smith, B. D., Gladstone, D. E., Carraway, H. E., Huff, C. A., Matsui, W. H., Bolaños-Meade, J., Jones, R. J. & Swinnen, L. J., Mar 1 2013, In : Leukemia and Lymphoma. 54, 3, p. 483-490 8 p.

Research output: Contribution to journalArticle

Partially Mismatched Transplantation and Human Leukocyte Antigen Donor-Specific Antibodies

Gladstone, D. E., Zachary, A. A., Fuchs, E. J., Luznik, L., Kasamon, Y. L., King, K. E., Brodsky, R. A., Jones, R. J. & Leffell, M. S., Apr 1 2013, In : Biology of Blood and Marrow Transplantation. 19, 4, p. 647-652 6 p.

Research output: Contribution to journalArticle

2012

Phase 1 dose-escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias

Zeidan, A. M., Ricklis, R. M., Carraway, H. E., Yun, H. D., Greer, J. M., Smith, B. D., Levis, M. J., McDevitt, M. A., Pratz, K. W., Showel, M. M., Gladstone, D. E., Gore, S. D. & Karp, J. E., Jul 1 2012, In : British journal of haematology. 158, 2, p. 198-207 10 p.

Research output: Contribution to journalArticle

Phase 2 study of rituximab-ABVD in classical Hodgkin lymphoma

Kasamon, Y. L., Jacene, H. A., Gocke, C. D., Swinnen, L. J., Gladstone, D. E., Perkins, B., Link, B. K., Popplewell, L. L., Habermann, T. M., Herman, J. M., Matsui, W. H., Jones, R. J. & Ambinder, R. F., May 3 2012, In : Blood. 119, 18, p. 4129-4132 4 p.

Research output: Contribution to journalArticle

Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias

Karp, J. E., Thomas, B. M., Greer, J. M., Sorge, C., Gore, S. D., Pratz, K. W., Smith, B. D., Flatten, K. S., Peterson, K., Schneider, P., Mackey, K., Freshwater, T., Levis, M. J., McDevitt, M. A., Carraway, H. E., Gladstone, D. E., Showel, M. M., Loechner, S., Parry, D. A., Horowitz, J. A. & 2 others, Isaacs, R. & Kaufmann, S. H., Dec 15 2012, In : Clinical Cancer Research. 18, 24, p. 6723-6731 9 p.

Research output: Contribution to journalArticle

Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia

Karp, J. E., Garrett-Mayer, E., Estey, E. H., Rudek, M. A., Douglas Smith, B., Greer, J. M., Michelle Drye, D., Mackey, K., Dorcy, K. S., Gore, S. D., Levis, M. J., McDevitt, M. A., Carraway, H. E., Pratz, K. W., Gladstone, D. E., Showel, M. M., Othus, M., Austin Doyle, L., Wright, J. J. & Pagel, J. M., Nov 1 2012, In : Haematologica. 97, 11, p. 1736-1742 7 p.

Research output: Contribution to journalArticle

The importance of IGHV mutational status in del(11q) and del(17p) chronic lymphocytic leukemia

Gladstone, D. E., Blackford, A., Cho, E., Swinnen, L., Kasamon, Y., Gocke, C. D., Griffin, C. A., Bolaños-Meade, J. & Jones, R. J., Apr 1 2012, In : Clinical Lymphoma, Myeloma and Leukemia. 12, 2, p. 132-137 6 p.

Research output: Contribution to journalArticle

2011

High-dose chemotherapy and multiple sclerosis

Harrison, D. & Gladstone, D. E., Mar 1 2011, In : Current opinion in oncology. 23, 2, p. 221-226 6 p.

Research output: Contribution to journalArticle

High-dose cyclophosphamide for moderate to severe refractory multiple sclerosis: 2-year follow-up (Investigational new Drug no. 65863)

Gladstone, D. E., Peyster, R., Baron, E., Friedman-Urevich, S., Sibony, P., Melville, P. & Gottesman, M., Jan 1 2011, In : American Journal of Therapeutics. 18, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

Importance of immunoglobulin heavy chain variable region mutational status in del(13q) chronic lymphocytic leukemia

Gladstone, D. E., Swinnen, L., Kasamon, Y., Blackford, A., Gocke, C. D., Griffin, C. A., Meade, J. B. & Jones, R. J., Oct 1 2011, In : Leukemia and Lymphoma. 52, 10, p. 1873-1881 9 p.

Research output: Contribution to journalArticle