Donald Small

Professor

1982 …2019
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Fingerprint Dive into the research topics where Donald Small is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Protein-Tyrosine Kinases Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Mutation Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
fms-Like Tyrosine Kinase 3 Medicine & Life Sciences
Precursor Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences
Stem Cells Medicine & Life Sciences

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Research Output 1982 2019

A novel RBMX-TFE3 gene fusion in a highly aggressive pediatric renal perivascular epithelioid cell tumor

Argani, P., Zhang, L., Sung, Y. S., White, M. J., Miller, K., Hopkins, M., Small, D., Pratilas, C., Swanson, D., Dickson, B. & Antonescu, C. R., Jan 1 2019, (Accepted/In press) In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

Perivascular Epithelioid Cell Neoplasms
Gene Fusion
Fluorescence In Situ Hybridization
Pediatrics
Kidney

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3

Nagai, K., Hou, L., Li, L., Nguyen, B., Seale, T., Shirley, C., Ma, H., Levis, M. J., Ghiaur, G., Duffield, A. S. & Small, D., Aug 31 2018, In : Oncotarget. 9, 68, p. 32885-32899 15 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Leukemia
Acute Myeloid Leukemia
Acute Promyelocytic Leukemia
Ubiquitination

Knock-In of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice

Annesley, C. E., Rabik, C., Duffield, A. S., Rau, R. E., Magoon, D., Li, L., Huff, V., Small, D., Loeb, D. M. & Brown, P. A., Oct 1 2018, In : Oncotarget. 9, 82, p. 35313-35326 14 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Wilms Tumor
Mutation
Neoplasms
Karyotype

Adaptation to TKI treatment reactivates ERK signaling in tyrosine kinase–driven leukemias and other malignancies

Bruner, J. K., Ma, H. S., Li, L., Qin, A. C. R., Rudek-Renaut, M., Jones, R. J., Levis, M. J., Pratz, K., Pratilas, C. & Small, D., Oct 15 2017, In : Cancer Research. 77, 20, p. 5554-5563 10 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Tyrosine
Leukemia
Neoplasms
Acute Myeloid Leukemia

DOCK2: A novel FLT3/ITD leukemia drug target

Wu, M., Small, D. & Duffield, A. S., 2017, In : Oncotarget. 8, 51, p. 88253-88254 2 p.

Research output: Contribution to journalEditorial

Acute Myeloid Leukemia
Leukemia
Pharmaceutical Preparations