Diane Abou

Instructor

20102018
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Research Output 2010 2018

  • 16 Article
  • 1 Conference contribution
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Article
2018

Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

McDevitt, M. R., Thorek, D. L. J., Hashimoto, T., Gondo, T., Veach, D. R., Sharma, S. K., Kalidindi, T. M., Abou, D., Watson, P. A., Beattie, B. J., Timmermand, O. V., Strand, S. E., Lewis, J. S., Scardino, P. T., Scher, H. I., Lilja, H., Larson, S. M. & Ulmert, D., Dec 1 2018, In : Nature Communications. 9, 1, 1629.

Research output: Contribution to journalArticle

Alpha Particles
Tissue Kallikreins
Alpha particles
Radiotherapy
Androgen Receptors

Targeting mitochondrial translation by inhibiting DDX3: A novel radiosensitization strategy for cancer treatment

Heerma Van Voss, M. R., Vesuna, F., Bol, G. M., Afzal, J., Tantravedi, S., Bergman, Y., Kammers, K., Lehar, M., Malek, R., Ballew, M., Ter Hoeve, N., Abou, D., Thorek, D., Berlinicke, C. A., Yazdankhah, M., Sinha, D., Le Thi, Q. H., Abrahams, R., Tran, P. T., Van Diest, P. J. & 1 othersRaman, V., Jan 4 2018, In : Oncogene. 37, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Oxygen Consumption
Reactive Oxygen Species
Respiratory Transport
DEAD-box RNA Helicases

The impact of age on radium-223 distribution and an evaluation of molecular imaging surrogates

Jiang, W., Ulmert, D., Simons, B. W., Abou, D. & Thorek, D. L. J., Jul 1 2018, In : Nuclear Medicine and Biology. 62-63, p. 1-8 8 p.

Research output: Contribution to journalArticle

Radium
Molecular Imaging
Technetium Tc 99m Medronate
Bone and Bones
Alpha Particles
2017

A Radium-223 microgenerator from cyclotron-produced trace Actinium-227

Abou, D., Pickett, J., Mattson, J. E. & Thorek, D. L. J., Jan 1 2017, In : Applied Radiation and Isotopes. 119, p. 36-42 7 p.

Research output: Contribution to journalArticle

actinium
radium
dichlorides
regeneration
bones

Listening to membrane potential: Photoacoustic voltage-sensitive dye recording

Zhang, H. K., Yan, P., Kang, J., Abou, D., Le, H. N. D., Jha, A. K., Thorek, D. L. J., Kang, J. U., Rahmim, A., Wong, D. F., Boctor, E. & Loew, L. M., Apr 1 2017, In : Journal of Biomedical Optics. 22, 4, 045006.

Research output: Contribution to journalArticle

Photoacoustic effect
Coloring Agents
Dyes
dyes
recording
2016

Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis

Thorek, D. L. J., Watson, P. A., Lee, S. G., Ku, A. T., Bournazos, S., Braun, K., Kim, K., Sjostrom, K., Doran, M. G., Lamminmaki, U., Santos, E., Veach, D., Turkekul, M., Casey, E., Lewis, J. S., Abou, D., Van Voss, M. R. H., Scardino, P. T., Strand, S. E., Alpaugh, M. L. & 4 othersScher, H. I., Lilja, H., Larson, S. M. & Ulmert, D., Nov 30 2016, In : Science Translational Medicine. 8, 367, 367ra167.

Research output: Contribution to journalArticle

Androgen Receptors
Antigens
Antibodies
Prostatic Neoplasms
Neoplasms

In vivo radiometric analysis of glucose uptake and distribution in mouse bone

Zoch, M. L., Abou, D., Clemens, T., Thorek, D. L. J. & Riddle, R., Apr 5 2016, In : Bone Research. 4, 16004.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Bone and Bones
Glucose
Osteoblasts
Osteogenesis

Pharmacokinetics of polymersomes composed of poly(Butadiene-Ethylene Oxide); Healthy versus tumor-bearing mice

Wang, G., De Kruijff, R. M., Abou, D., Ramos, N., Mendes, E., Franken, L. E., Wolterbeek, H. T. & Denkova, A. G., Feb 1 2016, In : Journal of Biomedical Nanotechnology. 12, 2, p. 320-328 9 p.

Research output: Contribution to journalArticle

Bearings (structural)
Ethylene Oxide
Pharmacokinetics
Butadiene
Tumors

Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis

Abou, D., Ulmert, D., Doucet, M., Hobbs, R., Riddle, R. & Thorek, D. L. J., May 1 2016, In : Journal of the National Cancer Institute. 108, 5, djv380.

Research output: Contribution to journalArticle

Radium
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
Castration
2015

Nuclear molecular imaging with nanoparticles: Radiochemistry, applications and translation

Abou, D., Pickett, J. E. & Thorek, D. L. J., Oct 1 2015, In : British Journal of Radiology. 88, 1054, 20150185.

Research output: Contribution to journalArticle

Radiochemistry
Molecular Imaging
Radioisotopes
Nanoparticles
Multimodal Imaging
2014

Non-invasive mapping of deep-tissue lymph nodes in live animals using a multimodal PET/MRI nanoparticle

Thorek, D. L. J., Ulmert, D., Diop, N. F. M., Lupu, M. E., Doran, M. G., Huang, R., Abou, D., Larson, S. M. & Grimm, J., Jan 20 2014, In : Nature Communications. 5, 3097.

Research output: Contribution to journalArticle

Positron emission tomography
lymphatic system
Magnetic resonance
drainage
Positron-Emission Tomography
Radiopharmaceuticals
Therapeutics
Radiation
Neoplasms
Pharmacokinetics
2013

89Zr-labeled paramagnetic octreotide-liposomes for PET-MR imaging of cancer

Abou, D., Thorek, D. L. J., Ramos, N. N., Pinkse, M. W. H., Wolterbeek, H. T., Carlin, S. D., Beattie, B. J. & Lewis, J. S., Mar 2013, In : Pharmaceutical Research. 30, 3, p. 878-888 11 p.

Research output: Contribution to journalArticle

Octreotide
Liposomes
Somatostatin Receptors
Chelating Agents
Imaging techniques
2012

Positron lymphography: Multimodal, high-resolution, dynamic mapping and resection of lymph nodes after intradermal injection of 18F-FDG

Thorek, D. L. J., Abou, D., Beattie, B. J., Bartlett, R. M., Huang, R., Zanzonico, P. B. & Grimm, J., Sep 1 2012, In : Journal of Nuclear Medicine. 53, 9, p. 1438-1445 8 p.

Research output: Contribution to journalArticle

Intradermal Injections
Lymphography
Fluorodeoxyglucose F18
Lymph Nodes
Electrons
2011

In vivo biodistribution and accumulation of 89Zr in mice

Abou, D., Ku, T. & Smith-Jones, P. M., Jul 2011, In : Nuclear Medicine and Biology. 38, 5, p. 675-681 7 p.

Research output: Contribution to journalArticle

Oxalates
Phosphates
Citric Acid
Chlorides
Bone and Bones
2010

Spin-echo small angle neutron scattering analysis of liposomes and bacteria

Van Heijkamp, L. F., Sevcenco, A. M., Abou, D., Van Luik, R., Krijger, G. C., Hagedoorn, P. L., De Schepper, I. M., Wolterbeek, B., Koning, G. A. & Bouwman, W. G., 2010, In : Journal of Physics: Conference Series. 247, 012016.

Research output: Contribution to journalArticle

bacteria
hollow
echoes
neutron scattering
drugs