Diane Abou

Instructor

20102018
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Research Output 2010 2018

  • 16 Article
  • 1 Conference contribution
2018

Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

McDevitt, M. R., Thorek, D. L. J., Hashimoto, T., Gondo, T., Veach, D. R., Sharma, S. K., Kalidindi, T. M., Abou, D. S., Watson, P. A., Beattie, B. J., Timmermand, O. V., Strand, S. E., Lewis, J. S., Scardino, P. T., Scher, H. I., Lilja, H., Larson, S. M. & Ulmert, D. Dec 1 2018 In : Nature Communications. 9, 1, 1629

Research output: Contribution to journalArticle

androgen
cancer
repair
targeting
DNA

Targeting mitochondrial translation by inhibiting DDX3: A novel radiosensitization strategy for cancer treatment

Heerma Van Voss, M. R. , Vesuna, F. , Bol, G. M. , Afzal, J. , Tantravedi, S. , Bergman, Y. , Kammers, K. , Lehar, M. , Malek, R. , Ballew, M. , Ter Hoeve, N. , Abou, D. , Thorek, D. , Berlinicke, C. , Yazdankhah, M. , Sinha, D. , Le, A. , Abrahams, R. , Tran, P. T. , Van Diest, P. J. & 1 others Raman, V. Jan 4 2018 In : Oncogene. 37, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Oxygen Consumption
Reactive Oxygen Species
Respiratory Transport
DEAD-box RNA Helicases

The impact of age on radium-223 distribution and an evaluation of molecular imaging surrogates

Jiang, W., Ulmert, D., Simons, B. W., Abou, D. S. & Thorek, D. L. J. Jul 1 2018 In : Nuclear Medicine and Biology. 62-63, p. 1-8 8 p.

Research output: Contribution to journalArticle

Radium
Molecular Imaging
Technetium Tc 99m Medronate
Bone and Bones
Alpha Particles
2017

A Radium-223 microgenerator from cyclotron-produced trace Actinium-227

Abou, D. S., Pickett, J., Mattson, J. E. & Thorek, D. L. J. Jan 1 2017 In : Applied Radiation and Isotopes. 119, p. 36-42 7 p.

Research output: Contribution to journalArticle

actinium
radium
dichlorides
regeneration
bones

Listening to membrane potential: Photoacoustic voltage-sensitive dye recording

Zhang, H. K., Yan, P., Kang, J., Abou, D. S., Le, H. N. D., Jha, A. K., Thorek, D. L. J., Kang, J. U., Rahmim, A., Wong, D. F., Boctor, E. M. & Loew, L. M. Apr 1 2017 In : Journal of Biomedical Optics. 22, 4, 045006

Research output: Contribution to journalArticle

Photoacoustic effect
Coloring Agents
Dyes
dyes
recording

Recording membrane potential changes through photoacoustic voltage sensitive dye

Zhang, H. K., Kang, J., Yan, P., Abou, D. S., Le, H. N. D., Thorek, D. L. J., Kang, J. U., Gjedde, A., Rahmim, A., Wong, D. F., Loew, L. M. & Boctor, E. M. 2017 Photons Plus Ultrasound: Imaging and Sensing 2017. SPIE, Vol. 10064, 1006407

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic effect
Membrane Potentials
Coloring Agents
Dyes
Fluorescence
2016

Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis

Thorek, D. L. J. , Watson, P. A. , Lee, S. G. , Ku, A. T. , Bournazos, S. , Braun, K. , Kim, K. , Sjostrom, K. , Doran, M. G. , Lamminmaki, U. , Santos, E. , Veach, D. , Turkekul, M. , Casey, E. , Lewis, J. S. , Abou, D. S. , Van Voss, M. R. H. , Scardino, P. T. , Strand, S. E. , Alpaugh, M. L. & 4 others Scher, H. I., Lilja, H., Larson, S. M. & Ulmert, D. Nov 30 2016 In : Science Translational Medicine. 8, 367, 367ra167

Research output: Contribution to journalArticle

Androgen Receptors
Antigens
Antibodies
Prostatic Neoplasms
Neoplasms

In vivo radiometric analysis of glucose uptake and distribution in mouse bone

Zoch, M. L., Abou, D. S., Clemens, T. L., Thorek, D. L. J. & Riddle, R. C. Apr 5 2016 In : Bone Research. 4, 16004

Research output: Contribution to journalArticle

Bone and Bones
Glucose
Osteoblasts
Fluorodeoxyglucose F18
Osteogenesis

Pharmacokinetics of polymersomes composed of poly(Butadiene-Ethylene Oxide); Healthy versus tumor-bearing mice

Wang, G., De Kruijff, R. M., Abou, D., Ramos, N., Mendes, E., Franken, L. E., Wolterbeek, H. T. & Denkova, A. G. Feb 1 2016 In : Journal of Biomedical Nanotechnology. 12, 2, p. 320-328 9 p.

Research output: Contribution to journalArticle

Bearings (structural)
Ethylene Oxide
Pharmacokinetics
Butadiene
Tumors
Radium
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
Castration
2015

Nuclear molecular imaging with nanoparticles: Radiochemistry, applications and translation

Abou, D. S., Pickett, J. E. & Thorek, D. L. J. Oct 1 2015 In : British Journal of Radiology. 88, 1054, 20150185

Research output: Contribution to journalArticle

Radiochemistry
Molecular Imaging
Radioisotopes
Nanoparticles
Multimodal Imaging
2014

Non-invasive mapping of deep-tissue lymph nodes in live animals using a multimodal PET/MRI nanoparticle

Thorek, D. L. J., Ulmert, D., Diop, N. F. M., Lupu, M. E., Doran, M. G., Huang, R., Abou, D. S., Larson, S. M. & Grimm, J. Jan 20 2014 In : Nature Communications. 5, 3097

Research output: Contribution to journalArticle

Positron emission tomography
lymphatic system
Magnetic resonance
drainage
Positron-Emission Tomography
Radiopharmaceuticals
Therapeutics
Radiation
Neoplasms
Pharmacokinetics
2013

89Zr-labeled paramagnetic octreotide-liposomes for PET-MR imaging of cancer

Abou, D. S., Thorek, D. L. J., Ramos, N. N., Pinkse, M. W. H., Wolterbeek, H. T., Carlin, S. D., Beattie, B. J. & Lewis, J. S. Mar 2013 In : Pharmaceutical Research. 30, 3, p. 878-888 11 p.

Research output: Contribution to journalArticle

Octreotide
Liposomes
Somatostatin Receptors
Chelating Agents
Imaging techniques
2012

Positron lymphography: Multimodal, high-resolution, dynamic mapping and resection of lymph nodes after intradermal injection of 18F-FDG

Thorek, D. L. J., Abou, D. S., Beattie, B. J., Bartlett, R. M., Huang, R., Zanzonico, P. B. & Grimm, J. Sep 1 2012 In : Journal of Nuclear Medicine. 53, 9, p. 1438-1445 8 p.

Research output: Contribution to journalArticle

Intradermal Injections
Lymphography
Fluorodeoxyglucose F18
Lymph Nodes
Electrons
2011

In vivo biodistribution and accumulation of 89Zr in mice

Abou, D. S., Ku, T. & Smith-Jones, P. M. Jul 2011 In : Nuclear Medicine and Biology. 38, 5, p. 675-681 7 p.

Research output: Contribution to journalArticle

Oxalates
Phosphates
Citric Acid
Chlorides
Bone and Bones
2010

Spin-echo small angle neutron scattering analysis of liposomes and bacteria

Van Heijkamp, L. F., Sevcenco, A. M., Abou, D., Van Luik, R., Krijger, G. C., Hagedoorn, P. L., De Schepper, I. M., Wolterbeek, B., Koning, G. A. & Bouwman, W. G. 2010 In : Journal of Physics: Conference Series. 247, 012016

Research output: Contribution to journalArticle

bacteria
hollow
echoes
neutron scattering
drugs