1992 …2020

Research output per year

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Research Output

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Electric-Field-Induced Structure in Polymer Solutions near the Critical Point

Wirtz, D., Berend, K. & Fuller, G. G., Dec 1 1992, In : Macromolecules. 25, 26, p. 7234-7246 13 p.

Research output: Contribution to journalArticle

Enhanced Viscoelasticity of Human Cystic Fibrotic Sputum Correlates with Increasing Microheterogeneity in Particle Transport

Dawson, M., Wirtz, D. & Hanes, J., Dec 12 2003, In : Journal of Biological Chemistry. 278, 50, p. 50393-50401 9 p.

Research output: Contribution to journalArticle

Evolution of cellular morpho-phenotypes in cancer metastasis

Wu, P. H., Phillip, J. M., Khatau, S. B., Chen, W. C., Stirman, J., Rosseel, S., Tschudi, K., Van Patten, J., Wong, M., Gupta, S., Baras, A. S., Leek, J. T., Maitra, A. & Wirtz, D., Dec 17 2015, In : Scientific reports. 5, 18437.

Research output: Contribution to journalArticle

Exploiting nucleation and growth in the synthesis and electrical passivation of CdSe quantum dots

Galloway, J. F., Park, J., Lee, K. H., Wirtz, D. & Searson, P. C., Apr 1 2009, In : Science of Advanced Materials. 1, 1, p. 93-100 8 p.

Research output: Contribution to journalArticle

Fibronectin fibrillogenesis regulates three-dimensional neovessel formation

Zhou, X., Rowe, R. G., Hiraoka, N., George, J. P., Wirtz, D., Mosher, D. F., Virtanen, I., Chernousov, M. A. & Weiss, S. J., May 1 2008, In : Genes and Development. 22, 9, p. 1231-1243 13 p.

Research output: Contribution to journalArticle

Flow-induced scattering peak in the structure factor of polymer solutions

Wirtz, D., Jan 1 1994, In : Physical Review E. 50, 3, p. R1755-R1758

Research output: Contribution to journalArticle

Fluctuation dynamics of a single magnetic chain

Silva, A. S., Bond, R., Plouraboué, F. & Wirtz, D., Dec 1 1996, In : Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 54, 5, p. 5502-5510 9 p.

Research output: Contribution to journalArticle

Fluctuation Enhancement and Reduction in Sheared Polymer Solutions

Wirtz, D., Sep 1 1994, In : Macromolecules. 27, 20, p. 5639-5642 4 p.

Research output: Contribution to journalArticle

Focal adhesion size uniquely predicts cell migration

Kim, D. H. & Wirtz, D., Apr 1 2013, In : FASEB Journal. 27, 4, p. 1351-1361 11 p.

Research output: Contribution to journalArticle

Form-finding model shows how cytoskeleton network stiffness is realized.

Gong, J., Zhang, D., Tseng, Y., Li, B., Wirtz, D. & Schafer, B. W., 2013, In : PloS one. 8, 10

Research output: Contribution to journalArticle

Open Access

Functional interplay between the cell cycle and cell phenotypes

Chen, W. C., Wu, P. H., Phillip, J. M., Khatau, S. B., Choi, J. M., Dallas, M. R., Konstantopoulos, K., Sun, S. X., Lee, J. S. H., Hodzic, D. & Wirtz, D., Mar 1 2013, In : Integrative Biology (United Kingdom). 5, 3, p. 523-534 12 p.

Research output: Contribution to journalArticle

Functional synergy of actin filament cross-linking proteins

Tseng, Y., Schafer, B. W., Almo, S. C. & Wirtz, D., Jul 12 2002, In : Journal of Biological Chemistry. 277, 28, p. 25609-25616 8 p.

Research output: Contribution to journalArticle

Going with the Flow: Water Flux and Cell Shape during Cytokinesis

Li, Y., He, L., Gonzalez, N. A. P., Graham, J., Wolgemuth, C., Wirtz, D. & Sun, S. X., Dec 5 2017, In : Biophysical Journal. 113, 11, p. 2487-2495 9 p.

Research output: Contribution to journalArticle

GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB

Esue, O., Wirtz, D. & Tseng, Y., Feb 1 2006, In : Journal of bacteriology. 188, 3, p. 968-976 9 p.

Research output: Contribution to journalArticle

High-frequency viscoelasticity of crosslinked actin filament networks measured by diffusing wave spectroscopy

Palmer, A., Xu, J. & Wirtz, D., Apr 1998, In : Rheologica Acta. 37, 2, p. 97-106 10 p.

Research output: Contribution to journalArticle

High-throughput ballistic injection nanorheology to measure cell mechanics

Wu, P. H., Hale, C. M., Chen, W. C., Lee, J. S. H., Tseng, Y. & Wirtz, D., Jan 1 2012, In : Nature protocols. 7, 1, p. 155-170 16 p.

Research output: Contribution to journalArticle

High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity

Lu, Y., Chen, J. J., Mu, L., Xue, Q., Wu, Y., Wu, P. H., Li, J., Vortmeyer, A. O., Miller-Jensen, K., Wirtz, D. & Fan, R., Feb 19 2013, In : Analytical chemistry. 85, 4, p. 2548-2556 9 p.

Research output: Contribution to journalArticle

How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response

Tseng, Y., Kole, T. P., Lee, J. S. H., Fedorov, E., Almo, S. C., Schafer, B. W. & Wirtz, D., Aug 19 2005, In : Biochemical and Biophysical Research Communications. 334, 1, p. 183-192 10 p.

Research output: Contribution to journalArticle

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

Wong, C. C. L., Gilkes, D. M., Zhang, H., Chen, J., Wei, H., Chaturvedi, P., Fraley, S. I., Wong, C. M., Khoo, U. S., Ng, I. O. L., Wirtz, D. & Semenza, G. L., Sep 27 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 39, p. 16369-16374 6 p.

Research output: Contribution to journalArticle

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

Gilkes, D. M., Xiang, L., Lee, S. J., Chaturvedi, P., Hubbi, M. E., Wirtz, D. & Semenza, G. L., Jan 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. E384-E393

Research output: Contribution to journalArticle

Open Access

Hypoxia Selectively Enhances Integrin α5β1 receptor expression in breast cancer to promote metastasis

Ju, J. A., Godet, I., Ye, I. C., Byun, J., Jayatilaka, H., Lee, S. J., Xiang, L., Samanta, D., Lee, M. H., Wu, P. H., Wirtz, D., Semenza, G. L. & Gilkes, D., Jun 1 2017, In : Molecular Cancer Research. 15, 6, p. 723-734 12 p.

Research output: Contribution to journalArticle

Immunolabeling of Cleared Human Pancreata Provides Insights into Three-Dimensional Pancreatic Anatomy and Pathology

Noë, M., Rezaee, N., Asrani, K., Skaro, M., Groot, V. P., Wu, P. H., Olson, M. T., Hong, S. M., Kim, S. J., Weiss, M. J., Wolfgang, C., Makary, M. A., He, J., Cameron, J. L., Wirtz, D., Roberts, N., Offerhaus, G. J. A., Brosens, L. A. A., Wood, L. D. & Hruban, R. H., Jul 1 2018, In : American Journal of Pathology. 188, 7, p. 1530-1535 6 p.

Research output: Contribution to journalArticle

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming

Suryo Rahmanto, Y., Shen, W., Shi, X., Chen, X., Yu, Y., Yu, Z. C., Miyamoto, T., Lee, M. H., Singh, V., Asaka, R., Shimberg, G., Vitolo, M. I., Martin, S. S., Wirtz, D., Drapkin, R., Xuan, J., Wang, T. L. & Shih, I. M., Dec 1 2020, In : Nature communications. 11, 1, 2717.

Research output: Contribution to journalArticle

Open Access

Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway

Yu, Y., Suryo Rahmanto, Y., Lee, M. H., Wu, P. H., Phillip, J. M., Huang, C. H., Vitolo, M. I., Gaillard, S., Martin, S. S., Wirtz, D., Shih, I. M. & Wang, T-L., Apr 11 2018, (Accepted/In press) In : Oncogene. p. 1-12 12 p.

Research output: Contribution to journalArticle

Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules

Yu, Y., Gaillard, S., Phillip, J. M., Huang, T. C., Pinto, S. M., Tessarollo, N. G., Zhang, Z., Pandey, A., Wirtz, D., Ayhan, A., Davidson, B., Wang, T. L. & Shih, I. M., Jul 13 2015, In : Cancer cell. 28, 1, p. 82-96 15 p.

Research output: Contribution to journalArticle

Interplay of RhoA and motility in the programmed spreading of daughter cells postmitosis

Mali, P., Wirtz, D. & Searson, P. C., Dec 1 2010, In : Biophysical journal. 99, 11, p. 3526-3534 9 p.

Research output: Contribution to journalArticle

Intracellular mechanics of migrating fibroblasts

Kole, T. P., Tseng, Y., Jiang, I., Katz, J. L. & Wirtz, D., Jan 1 2005, In : Molecular biology of the cell. 16, 1, p. 328-338 11 p.

Research output: Contribution to journalArticle

Isomeric control of the mechanical properties of supramolecular filament hydrogels

Lin, Y. A., Kang, M., Chen, W. C., Ou, Y. C., Cheetham, A. G., Wu, P. H., Wirtz, D., Loverde, S. M. & Cui, H., Jan 2018, In : Biomaterials science. 6, 1, p. 216-224 9 p.

Research output: Contribution to journalArticle

Keratin filament suspensions show unique micromechanical properties

Ma, L., Xu, J., Coulombe, P. A. & Wirtz, D., Jul 2 1999, In : Journal of Biological Chemistry. 274, 27, p. 19145-19151 7 p.

Research output: Contribution to journalArticle

Linear viscoelastic moduli of concentrated DNA solutions

Mason, T. G., Dhople, A. & Wirtz, D., Jun 2 1998, In : Macromolecules. 31, 11, p. 3600-3603 4 p.

Research output: Contribution to journalArticle

Local 3D matrix confinement determines division axis through cell shape

He, L., Chen, W., Wu, P. H., Jimenez, A., Wong, B. S., San, A., Konstantopoulos, K. & Wirtz, D., Jan 1 2016, In : Oncotarget. 7, 6, p. 6994-7011 18 p.

Research output: Contribution to journalArticle

Local dynamics and viscoelastic properties of cell biological systems

Tseng, Y., Kole, T. P., Lee, S. H. J. & Wirtz, D., Aug 2002, In : Current Opinion in Colloid and Interface Science. 7, 3-4, p. 210-217 8 p.

Research output: Contribution to journalArticle

Local mechanical response of cells to the controlled rotation of magnetic nanorods

Castillo, M., Ebensperger, R., Wirtz, D., Walczak, M., Hurtado, D. E. & Celedon, A., Nov 1 2014, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 102, 8, p. 1779-1785 7 p.

Research output: Contribution to journalArticle

Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness

Stroka, K. M., Wong, B. S., Shriver, M., Phillip, J. M., Wirtz, D., Kontrogianni-Konstantopoulos, A. & Konstantopoulos, K., Jan 1 2017, In : Oncotarget. 8, 33, p. 54004-54020 17 p.

Research output: Contribution to journalArticle

Loss of α-catenin decreases the strength of single E-cadherin bonds between human cancer cells

Bajpai, S., Feng, Y., Krishnamurthy, R., Longmore, G. D. & Wirtz, D., Jul 3 2009, In : Journal of Biological Chemistry. 284, 27, p. 18252-18259 8 p.

Research output: Contribution to journalArticle

Magnetic manipulation of nanorods in the nucleus of living cells

Celedon, A., Hale, C. M. & Wirtz, D., Oct 19 2011, In : Biophysical journal. 101, 8, p. 1880-1886 7 p.

Research output: Contribution to journalArticle

Magnetic tweezers for DNA micromanipulation

Haber, C. & Wirtz, D., Dec 2000, In : Review of Scientific Instruments. 71, 12, p. 4561-4570 10 p.

Research output: Contribution to journalArticle

Magnetic tweezers measurement of single molecule torque

Celedon, A., Nodelman, I. M., Wildt, B., Dewan, R., Searson, P., Wirtz, D., Bowman, G. D. & Sun, S. X., Apr 8 2009, In : Nano Letters. 9, 4, p. 1720-1725 6 p.

Research output: Contribution to journalArticle

Mammalian cell division in 3D matrices via quantitative confocal reflection microscopy

He, L., Sneider, A., Chen, W., Karl, M., Prasath, V., Wu, P. H., Mattson, G. & Wirtz, D., Nov 29 2017, In : Journal of Visualized Experiments. 2017, 129, e56364.

Research output: Contribution to journalArticle

Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking

Bloom, R. J., George, J. P., Celedon, A., Sun, S. X. & Wirtz, D., Oct 15 2008, In : Biophysical journal. 95, 8, p. 4077-4088 12 p.

Research output: Contribution to journalArticle

Materials science of the cell

Wirtz, D. & Evans, E., Dec 1 1999, In : MRS Bulletin. 24, 10, p. 19-20 2 p.

Research output: Contribution to journalArticle

Mechanical shear can accelerate the gelation of actin filament networks

Esue, O., Tseng, Y. & Wirtz, D., Jul 22 2005, In : Physical Review Letters. 95, 4, 048301.

Research output: Contribution to journalArticle

Mechanics and dynamics of actin-driven thin membrane protrusions

Atilgan, E., Wirtz, D. & Sun, S. X., Jan 2006, In : Biophysical journal. 90, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

Mechanics and multiple-particle tracking microheterogeneity of α-actinin-cross-linked actin filament networks

Tseng, Y. & Wirtz, D., Jan 1 2001, In : Biophysical journal. 81, 3, p. 1643-1656 14 p.

Research output: Contribution to journalArticle

Open Access

Mechanics of enveloped virus entry into host cells

Sun, S. X. & Wirtz, D., Jan 2006, In : Biophysical journal. 90, 1, p. L10-L12

Research output: Contribution to journalArticle

Mechanics of living cells measured by laser tracking microrheology

Yamada, S., Wirtz, D. & Kuo, S. C., Apr 2000, In : Biophysical journal. 78, 4, p. 1736-1747 12 p.

Research output: Contribution to journalArticle

Open Access

Metabolic and Mechanical Cues Regulating Pluripotent Stem Cell Fate

Perestrelo, T., Correia, M., Ramalho-Santos, J. & Wirtz, D., Jan 1 2018, (Accepted/In press) In : Trends in Cell Biology.

Research output: Contribution to journalArticle

MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion

Daniels, B. R., Dobrowsky, T. M., Perkins, E. M., Sun, S. X. & Wirtz, D., Aug 1 2010, In : Development. 137, 15, p. 2579-2585 7 p.

Research output: Contribution to journalArticle