Debra J Mathews

Associate Professor

19992020

Research output per year

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Research Output

1999

GIST: A web tool for collecting gene information

Halushka, M. K., Mathews, D. J., Bailey, J. A. & Chakravarti, A., Dec 1 1999, In : Physiological Genomics. 1999, 1, p. 75-81 7 p.

Research output: Contribution to journalArticle

2001

High-throughput variation detection and genotyping using microarrays

Cutler, D. J., Zwick, M. E., Carrasquillo, M. M., Yohn, C. T., Tobin, K. P., Kashuk, C., Mathews, D. J., Shah, N. A., Eichler, E. E., Warrington, J. A. & Chakravarti, A., Dec 11 2001, In : Genome research. 11, 11, p. 1913-1925 13 p.

Research output: Contribution to journalArticle

Sequence variation within the fragile X locus

Mathews, D. J., Kashuk, C., Brightwell, G., Eichler, E. E. & Chakravarti, A., Sep 1 2001, In : Genome research. 11, 8, p. 1382-1391 10 p.

Research output: Contribution to journalArticle

2002

Encouraging everyday lab ethics

Mathews, D. J., Jul 8 2002, In : Scientist. 16, 14, 1 p.

Research output: Contribution to journalShort survey

2005

Geneticists' views on science policy formation and public outreach

Mathews, D. J. H., Kalfoglou, A. & Hudson, K., Aug 30 2005, In : American Journal of Medical Genetics. 137 A, 2, p. 161-169 9 p.

Research output: Contribution to journalReview article

Opinions about new reproductive genetic technologies: Hopes and fears for our genetic future

Kalfoglou, A. L., Doksum, T., Bernhardt, B., Geller, G., LeRoy, L., Mathews, D. J. H., Evans, J. H., Doukas, D. J., Reame, N., Scott, J. & Hudson, K., Jun 1 2005, In : Fertility and sterility. 83, 6, p. 1612-1621 10 p.

Research output: Contribution to journalArticle

Resisting the tide of professionalization: Valuing diversity in bioethics

Regenberg, A. C. & Mathews, D. J. H., Sep 1 2005, In : American Journal of Bioethics. 5, 5, p. 44-45 2 p.

Research output: Contribution to journalComment/debate

2006

Integrity in international stem cell research collaborations

Mathews, D. J. H., Donovan, P., Harris, J., Lovell-Badge, R., Savulescu, J. & Faden, R., Aug 18 2006, In : Science. 313, 5789, p. 921-922 2 p.

Research output: Contribution to journalShort survey

2007

Neuroethics: An Introduction

Mathews, D. J. H. & Rabins, P., Jul 1 2007, In : Neurotherapeutics. 4, 3, p. 523-524 2 p.

Research output: Contribution to journalEditorial

Stem Cell Research Ethics: Consensus Statement on Emerging Issues

Caulfield, T., Ogbogu, U., Nelson, E., Einsiedel, E., Knoppers, B., McDonald, M., Brunger, F., Downey, R., Fernando, K., Galipeau, J., Geransar, R., Grenier, G., Hyun, I., Isasi, R., Kardel, M., Knowles, L., Kucic, T., Lotjonen, S., Lyall, D., Magnus, D. & 9 others, Mathews, D. J. H., Nisbet, M., Nisker, J., Pare, G., Pattinson, S., Pullman, D., Rudnicki, M., Williams-Jones, B. & Zimmerman, S., Jan 1 2007, In : Journal of Obstetrics and Gynaecology Canada. 29, 10, p. 843-848 6 p.

Research output: Contribution to journalArticle

2008

Cell-based interventions for neurologic conditions: Ethical challenges for early human trials

Mathews, D. J. H., Sugarman, J., Bok, H., Blass, D. M., Coyle, J. T., Duggan, P., Finkel, J., Greely, H. T., Hillis, A., Hoke, A., Johnson, R., Johnston, M., Kahn, J., Kerr, D., Kurtzberg, J., Liao, S. M., McDonald, J. W., McKhann, G., Nelson, K. B., Rao, M. & 9 others, Regenberg, A., Siegel, A. W., Smith, K., Solter, D., Song, H., Vescovi, A., Young, W., Gearhart, J. D. & Faden, R., Jul 22 2008, In : Neurology. 71, 4, p. 288-293 6 p.

Research output: Contribution to journalReview article

2009

A "two cultures" phrasebook

Mathews, D. J. H., Regenberg, A. & Duggan, P., Dec 1 2009, Personal Identity and Fractured Selves: Perspectives from Philosophy, Ethics, and Neuroscience. The Johns Hopkins University Press, p. 1-12 12 p.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Common threads

Bok, H., Mathews, D. J. H. & Rabins, P. V., Dec 1 2009, Personal Identity and Fractured Selves: Perspectives from Philosophy, Ethics, and Neuroscience. The Johns Hopkins University Press, p. 187-193 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Medicine on the fringe: Stem cell-based interventions in advance of evidence

Regenberg, A. C., Hutchinson, L. A., Schanker, B. & Mathews, D. J. H., Sep 1 2009, In : Stem Cells. 27, 9, p. 2312-2319 8 p.

Research output: Contribution to journalArticle

Of mice and men: Skin cells, stem cells and ethical uncertainties

Sugarman, J. & Mathews, D. J. H., Nov 1 2009, In : Regenerative Medicine. 4, 6, 1 p.

Research output: Contribution to journalLetter

Pluripotent Stem Cell-Derived Gametes: Truth and (Potential) Consequences

Mathews, D. J. H., Donovan, P. J., Harris, J., Lovell-Badge, R., Savulescu, J. & Faden, R., Jul 2 2009, In : Cell stem cell. 5, 1, p. 11-14 4 p.

Research output: Contribution to journalComment/debate

Reply from the Authors

Mathews, D. J. H., Sugarman, J. & Faden, R., May 12 2009, In : Neurology. 72, 19, 1 p.

Research output: Contribution to journalLetter

Scientific and ethical issues related to deep brain stimulation for disorders of mood, behavior, and thought

Rabins, P., Appleby, B. S., Brandt, J., DeLong, M. R., Dunn, L. B., Gabriëls, L., Greenberg, B. D., Haber, S. N., Holtzheimer, P. E., Mari, Z., Mayberg, H. S., McCann, E., Mink, S. P., Rasmussen, S., Schlaepfer, T. E., Vawter, D. E., Vitek, J. L., Walkup, J. & Mathews, D. J. H., Sep 1 2009, In : Archives of general psychiatry. 66, 9, p. 931-937 7 p.

Research output: Contribution to journalReview article

The role of animal models in evaluating reasonable safety and efficacy for human trials of cell-based interventions for neurologic conditions

Regenberg, A., Mathews, D. J. H., Blass, D. M., Bok, H., Coyle, J. T., Duggan, P., Faden, R., Finkel, J., Gearhart, J. D., Hillis, A., Hoke, A., Johnson, R., Johnston, M., Kahn, J., Kerr, D., King, P., Kurtzberg, J., Liao, S. M., McDonald, J. W., McKhann, G. & 11 others, Nelson, K. B., Rao, M., Siegel, A. W., Smith, K., Solter, D., Song, H., Sugarman, J., Vescovi, A., Young, W., Greely, H. T. & Traystman, R. J., Jan 1 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 1, p. 1-9 9 p.

Research output: Contribution to journalReview article

Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: Ethical challenges

Duggan, P. S., Siegel, A. W., Blass, D. M., Bok, H., Coyle, J. T., Faden, R., Finkel, J., Gearhart, J. D., Greely, H. T., Hillis, A., Hoke, A., Johnson, R., Johnston, M., Kahn, J., Kerr, D., King, P., Kurtzberg, J., Liao, S. M., McDonald, J. W., McKhann, G. & 12 others, Nelson, K. B., Rao, M., Regenberg, A., Smith, K., Solter, D., Song, H., Sugarman, J., Traystman, R. J., Vescovi, A., Yanofski, J., Young, W. & Mathews, D. J. H., May 2009, In : American Journal of Bioethics. 9, 5, p. 31-36 6 p.

Research output: Contribution to journalArticle

2011

Access to stem cells and data: Persons, property rights, and scientific progress

Mathews, D. J. H., Graff, G. D., Saha, K. & Winickoff, D. E., Feb 11 2011, In : Science. 331, 6018, p. 725-727 3 p.

Research output: Contribution to journalShort survey

Deep brain stimulation, personal identity and policy

Mathews, D. J. H., Oct 1 2011, In : International Review of Psychiatry. 23, 5, p. 486-492 7 p.

Research output: Contribution to journalArticle

Promoting justice in stem cell intellectual property

Regenberg, A. & Mathews, D. J. H., Nov 1 2011, In : Regenerative Medicine. 6, 6 SUPPL., p. 79-84 6 p.

Research output: Contribution to journalReview article

2012

Deep Brain Stimulation For Treatment-Resistant Neuropsychiatric Disorders

Mathews, D. J., Rabins, P. V. & Greenberg, B. D., Nov 21 2012, Oxford Handbook of Neuroethics. Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Patents and misplaced angst: Lessons for translational stem cell research from genomics

Mathews, D. J. H., Cook-Deegan, R. & Bubela, T., May 2 2013, In : Cell stem cell. 12, 5, p. 508-512 5 p.

Research output: Contribution to journalComment/debate

2014

Beyond consent in research: Revisiting vulnerability in deep brain stimulation for psychiatric disorders

Bell, E., Racine, E., Chiasson, P., Dufourcq-Brana, M., Dunn, L. B., Fins, J. J., Ford, P. J., Glannon, W., Lipsman, N., Macdonald, M. E., Mathews, D. J. H. & McAndrews, M. P., Jul 2014, In : Cambridge Quarterly of Healthcare Ethics. 23, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

Language matters

Mathews, D. J. H., Jan 1 2014, In : Journal of medical ethics. 40, 11, p. 733-734 2 p.

Research output: Contribution to journalArticle

Patients' attitudes toward the donation of biological materials for the derivation of induced pluripotent stem cells

Dasgupta, I., Bollinger, J., Mathews, D. J. H., Neumann, N. M., Rattani, A. & Sugarman, J., Jan 2 2014, In : Cell stem cell. 14, 1, p. 9-12 4 p.

Research output: Contribution to journalComment/debate

Policies and practices to enhance multi-sectorial collaborations and commercialization of regenerative medicine

Bubela, T., Mishra, A. & Mathews, D., Oct 1 2014, Regenerative Medicine Ethics: Governing Research and Knowledge Practices. Springer New York, Vol. 9781461490623. p. 67-87 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Revisiting respect for persons in genomic research

Mathews, D. J. H. & Jamal, L., Mar 1 2014, In : Genes. 5, 1, p. 1-12 12 p.

Research output: Contribution to journalComment/debate

2015

Brain research on morality and cognition

Mathews, D. J. H. & Bok, H., Jan 1 2015, Handbook of Neuroethics. Springer Netherlands, p. 1151-1166 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

CRISPR: A path through the thicket

Mathews, D. J. H., Chan, S., Donovan, P. J., Douglas, T., Gyngell, C., Harris, J., Regenberg, A. & Lovell-Badge, R., Nov 10 2015, In : Nature. 527, 7577, p. 159-161 3 p.

Research output: Contribution to journalComment/debate

Freedom and responsibility in synthetic genomics: The synthetic yeast project

Sliva, A., Yang, H., Boeke, J. D. & Mathews, D. J. H., Aug 1 2015, In : Genetics. 200, 4, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement

Hinxton Group, 2015, In : American Journal of Bioethics. 15, 12, p. 42-47 6 p.

Research output: Contribution to journalComment/debate

The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities

Chong, J. X., Buckingham, K. J., Jhangiani, S. N., Boehm, C., Sobreira, N., Smith, J. D., Harrell, T. M., McMillin, M. J., Wiszniewski, W., Gambin, T., Coban Akdemir, Z. H., Doheny, K., Scott, A. F., Avramopoulos, D., Chakravarti, A., Hoover-Fong, J., Mathews, D., Witmer, P. D., Ling, H., Hetrick, K. & 22 others, Watkins, L., Patterson, K. E., Reinier, F., Blue, E., Muzny, D., Kircher, M., Bilguvar, K., López-Giráldez, F., Sutton, V. R., Tabor, H. K., Leal, S. M., Gunel, M., Mane, S., Gibbs, R. A., Boerwinkle, E., Hamosh, A., Shendure, J., Lupski, J. R., Lifton, R. P., Valle, D., Nickerson, D. A. & Bamshad, M. J., Aug 6 2015, In : American journal of human genetics. 97, 2, p. 199-215 17 p., 1908.

Research output: Contribution to journalReview article

2016

A Conceptual Model for the Translation of Bioethics Research and Scholarship

Mathews, D. J. H., Hester, D. M., Kahn, J., McGuire, A., McKinney, R., Meador, K., Philpott-Jones, S., Youngner, S. & Wilfond, B. S., Sep 1 2016, In : Hastings Center Report. 46, 5, p. 34-39 6 p.

Research output: Contribution to journalArticle

Physicians' perspectives regarding pragmatic clinical trials

Topazian, R., Bollinger, J., Weinfurt, K. P., Dvoskin, R., Mathews, D. J., Brelsford, K., DeCamp, M. & Sugarman, J., Aug 1 2016, In : Journal of Comparative Effectiveness Research. 5, 5, p. 499-506 8 p.

Research output: Contribution to journalArticle

2017

Choices for return of primary and secondary genomic research results of 790 members of families with Mendelian disease

Fiallos, K., Applegate, C., Mathews, D. J., Bollinger, J., Bergner, A. L. & James, C. A., May 1 2017, In : European Journal of Human Genetics. 25, 5, p. 530-537 8 p.

Research output: Contribution to journalArticle

When emerging biomedical technologies converge or collide

Mathews, D. J., Jan 1 2017, Neuroethics: Anticipating the Future. Oxford University Press, p. 3-14 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing?

Mitchell, P. B., Ziniel, S. I., Savage, S. K., Christensen, K. D., Weitzman, E. R., Green, R. C., Huntington, N. L., Mathews, D. J. & Holm, I. A., Jan 1 2018, (Accepted/In press) In : Journal of Empirical Research on Human Research Ethics.

Research output: Contribution to journalArticle

Free Will, Self-Governance and Neuroscience: An Overview

Carse, A., Bok, H. & Mathews, D. J., Jan 1 2018, (Accepted/In press) In : Neuroethics.

Research output: Contribution to journalArticle

Perspectives on Genetic Testing and Return of Results from the First Cohort of Presymptomatically Tested Individuals At Risk of Huntington Disease

Stuttgen, K. M., Bollinger, J. M., Dvoskin, R. L., McCague, A., Shpritz, B., Brandt, J. & Mathews, D. J., Jul 2 2018, (Accepted/In press) In : Journal of Genetic Counseling. p. 1-10 10 p.

Research output: Contribution to journalArticle

Risk perception before and after presymptomatic genetic testing for Huntington's disease: Not always what one might expect

Stuttgen, K., Dvoskin, R., Bollinger, J., McCague, A., Shpritz, B., Brandt, J. & Mathews, D. J., Jan 1 2018, (Accepted/In press) In : Molecular Genetics and Genomic Medicine.

Research output: Contribution to journalArticle

The Therapeutic Misconception: An Examination of its Normative Assumptions and a Call for its Revision

Mathews, D. J., Fins, J. J. & Racine, E., Jan 1 2018, In : Cambridge Quarterly of Healthcare Ethics. 27, 1, p. 154-162 9 p.

Research output: Contribution to journalReview article

2019

Ethical framework for including research biopsies in oncology clinical trials: American Society of Clinical oncology research statement

Levit, L. A., Peppercorn, J. M., Tam, A. L., Marron, J. M., Mathews, D. J. H., Levit, K., Roach, N. & Ratain, M. J., Sep 10 2019, In : Journal of Clinical Oncology. 37, 26, p. 2368-2377 10 p.

Research output: Contribution to journalArticle

Patient Preferences for Use of Archived Biospecimens from Oncology Trials When Adequacy of Informed Consent Is Unclear

Peppercorn, J., Campbell, E., Isakoff, S., Horick, N. K., Rabin, J., Quain, K., Sequist, L. V., Bardia, A., Collyar, D., Hlubocky, F. & Mathews, D. J., Jan 1 2019, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Secondary Use of Patient Tissue in Cancer Biobanks

Mathews, D. J., Rabin, J. T., Quain, K., Campbell, E., Collyar, D., Hlubocky, F. J., Isakoff, S. & Peppercorn, J., Jan 1 2019, In : Oncologist.

Research output: Contribution to journalArticle

2020

Artificial Intelligence in Service of Human Needs: Pragmatic First Steps Toward an Ethics for Semi-Autonomous Agents

Rieder, T. N., Hutler, B. & Mathews, D. J. H., Apr 2 2020, In : AJOB Neuroscience. 11, 2, p. 120-127 8 p.

Research output: Contribution to journalArticle