Dean F Mackinnon

Associate Professor

1989 …2019

Research output per year

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Research Output

1989

Autobiographical memory and amnesia

Mackinnon, D. F. & Squire, L. R., 1989, In : Psychobiology. 17, 3, p. 247-256 10 p.

Research output: Contribution to journalArticle

1997

A novel, heritable, expanding CTG repeat in an intron of the SEF2-1 gene on chromosome 18q21.1

Breschel, T. S., McInnis, M. G., Margolis, R. L., Sirugo, G., Corneliussen, B., Simpson, S. G., McMahon, F. J., MacKinnon, D. F., Xu, J. F., Pleasant, N., Huo, Y., Ashworth, R. G., Grundstrom, C., Grundstrom, T., Kidd, K. K., DePaulo, J. R. & Ross, C. A., Oct 1 1997, In : Human molecular genetics. 6, 11, p. 1855-1863 9 p.

Research output: Contribution to journalArticle

Genetics of manic depressive illness

MacKinnon, D. F., Jamison, K. R. & DePaulo, J. R., Mar 17 1997, In : Annual review of neuroscience. 20, p. 355-373 19 p.

Research output: Contribution to journalReview article

Initial genome scan of the nimh genetics initiative bipolar pedigrees: Chromosomes 1, 6, 8, 10, and 12

Rice, J. P., Goate, A., Williams, J. T., Bierut, L., Dorr, D., Wu, W., Shears, S., Gopalakrishnan, G., Edenberg, H. J., Foroud, T., Nurnberger, J., Gershon, E. S., Detera-Wadleigh, S. D., Goldin, L. R., Guroff, J. J., McMahon, F. J., Simpson, S., Mackinnon, D. F., McInnis, M., Stine, O. C. & 3 others, Depaulo, J. R., Blehar, M. C. & Reich, T., 1997, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 74, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 4, 7, 9, 18, 19, 20, and 21q

Detera-Wadleigh, S. D., Badner, J. A., Yoshikawa, T., Sanders, A. R., Goldin, L. R., Turner, G., Rolling, D. Y., Moses, T., Guroff, J. J., Kazuba, D., Maxwell, M. E., Edenberg, H. J., Foroud, T., Lahiri, D., Nurnberger, J. I., Stine, O. C., McMahon, F., Meyers, D. A., Mackinnon, D. F., Simpson, S. & 7 others, McInnis, M., Depaulo, J. R., Rice, J., Goate, A., Reich, T., Blehar, M. C. & Gershon, E. S., 1997, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 74, 3, p. 254-262 9 p.

Research output: Contribution to journalArticle

Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: Chromosomes 2, 11, 13, 14, and x

Stine, O. C., McMahon, F. J., Chen, L. S., Xu, J., Meyers, D. A., MacKinnon, D. F., Simpson, S., McInnis, M. G., Rice, J. P., Goate, A., Reich, T., Edenberg, H. J., Foroud, T., Nurnberger, J. I., Detera-Wadleigh, S. D., Goldin, L. R., Guroff, J., Gershon, E. S., Blehar, M. C. & DePaulo, J. R., Jun 26 1997, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 74, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series

McMahon, F. J., Hopkins, P. J., Xu, J., McInnis, M. G., Shaw, S., Cardon, L., Simpson, S. G., MacKinnon, D. F., Stine, O. C., Sherrington, R., Meyers, D. A. & DePaulo, J. R., Dec 1997, In : American journal of human genetics. 61, 6, p. 1397-1404 8 p.

Research output: Contribution to journalArticle

Panic disorder with familial bipolar disorder

MacKinnon, D. F., McMahon, F. J., Simpson, S. G., McInnis, M. G. & DePaulo, J. R., Jul 15 1997, In : Biological psychiatry. 42, 2, p. 90-95 6 p.

Research output: Contribution to journalArticle

1998

Bipolar disorder and panic disorder in families: An analysis of chromosome 18 data

MacKinnon, D. F., Xu, J., McMahon, F. J., Simpson, S. G., Stine, O. C., Mclnnis, M. G. & DePaulo, J. R., Jun 13 1998, In : American Journal of Psychiatry. 155, 6, p. 829-831 3 p.

Research output: Contribution to journalArticle

Evidence for a susceptibility locus for bipolar disorder on chromosome 11p11.5

McInnis, M. G., Mackinnon, D. F., McMahon, F. J., Foroud, T., Edenberg, H. J., Goate, A., Detera-Wadleigh, S., Stine, O. C., Rice, J., Blehar, M., Reich, T., Gershon, E., Nurnberger, J. I., Simpson, S. G. & Depaulo, J. R., Nov 6 1998, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 81, 6, p. 463 1 p.

Research output: Contribution to journalArticle

Medication patterns of recurrent headache sufferers: A community study

Forward, S. P., McGrath, P. J., MacKinnon, D., Brown, T. L., Swann, J. & Currie, E. L., May 18 1998, In : Cephalalgia. 18, 3, p. 146-151 6 p.

Research output: Contribution to journalArticle

Sibs affected with BPII are more likely than sibs with BPI to share the linked region on chromosome 18q21

McMahon, F. J., Simpson, S. G., McInnis, M. G., MacKinnon, D. A. & DePaulo, J. R., Nov 6 1998, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 81, 6, 1 p.

Research output: Contribution to journalArticle

Supportive evidence for a bipolar susceptibility gene on chromosome 4q35

McInnis, M. G., McMahon, F. J., MacKinnon, D. F., Breschel, T. S., Simpson, S. G. & DePaulo, J. R., Nov 6 1998, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 81, 6, 1 p.

Research output: Contribution to journalArticle

The relationship between alcoholism and bipolar affective disorder: Association in families of comorbid probands

McMahon, F. J., Thomas, C. J. M., MacKinnon, D. A., Simpson, S. G., McInnis, M. G. & Depaulo, J. R., Nov 6 1998, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 81, 6, p. 491-492 2 p.

Research output: Contribution to journalArticle

1999

Family-based association analysis of the hSKCa3 potassium channel gene in bipolar disorder [4]

McInnis, M. G., Breschel, T. S., Margolis, R. L., Chellis, J., Mackinnon, D. F., McMahon, F. J., Simpson, S. G., Lan, T. H., Chen, H., Ross, C. A. & Depaulo, J. R., 1999, In : Molecular Psychiatry. 4, 3, p. 217-219 3 p.

Research output: Contribution to journalArticle

2000

Allelic distribution of CTG18.1 in Caucasian populations: Association studies in bipolar disorder, schizophrenia, and ataxia

McInnis, M. G., Swift-Scanlanl, T., Mahoney, A. T., Vincent, J., Verheyen, G., Hung Lan, T., Oruc, L., Riess, O., Van Broeckhoven, C., Chen, H., Kennedy, J. L., Mackinnon, D. F., Margolis, R. L., Simpson, S. G., McMahon, F. J., Gershon, E., Nürnberger, J., Reich, T., Depaulo, J. R. & Ross, C. A., 2000, In : Molecular Psychiatry. 5, 4, p. 439-442 4 p.

Research output: Contribution to journalArticle

Attempted suicide and alcoholism in bipolar disorder: Clinical and familial relationships

Potash, J. B., Kane, H. S., Chiu, Y. F., Simpson, S. G., MacKinnon, D. F., McInnis, M. G., McMahon, F. J. & De Paulo, J., Dec 18 2000, In : American Journal of Psychiatry. 157, 12, p. 2048-2050 3 p.

Research output: Contribution to journalArticle

Bipolar disorder: The correlation of 3 analytic results for a genome-wide parent of origin effect

McInnis, M. G., Lan, T. H., Willour, V., Mahoney, A. T., Chellis, J., McMahon, F. J., Mackinnon, D. F., Potash, J. B., Simpson, S. G., Beaty, T. L. & Depaulo, J. R., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, p. 546-547 2 p.

Research output: Contribution to journalArticle

Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype

Friddle, C., Koskela, R., Ranade, K., Hebert, J., Cargill, M., Clark, C. D., McInnis, M., Simpson, S., McMahon, F., Stine, O. C., Meyers, D., Xu, J., Mackinnon, D. F., Swift-Scanlan, T., Jamison, K., Folstein, S., Daly, M., Kruglyak, L., Marr, T., Depaulo, J. R. & 1 others, Botstein, D., 2000, In : American Journal of Human Genetics. 66, 1, p. 205-215 11 p.

Research output: Contribution to journalArticle

Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees

Foroud, T., Castelluccio, P. F., Koller, D. L., Edenberg, H. J., Miller, M., Bowman, E., Rau, N. L., Smiley, C., Rice, J. P., Goate, A., Armstrong, C., Bierut, L. J., Reich, T., Detera-Wadleigh, S. D., Goldin, L. R., Badner, J. A., Guroff, J. J., Gershon, E. S., McMahon, F. J., Simpson, S. & 6 others, MacKinnon, D., McInnis, M., Stine, O. C., DePaulo, J. R., Blehar, M. C. & Nurnberger, J. I., Feb 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

The familiality of psychotic symptoms in bipolar disorder pedigrees

Potash, J. B., Willour, V. L., McInnis, M. G., MacKinnon, D. F., Simpson, S. G. & DePaulo, J. R., Aug 7 2000, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, 1 p.

Research output: Contribution to journalArticle

2001

Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder

McMahon, F. J., Simpson, S. G., McInnis, M. G., Badner, J. A., MacKinnon, D. F. & DePaulo, R., Jan 1 2001, In : Archives of general psychiatry. 58, 11, p. 1025-1031 7 p.

Research output: Contribution to journalArticle

Open Access

NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene

Chen, H., Ross, C. A., Wang, N., Huo, Y., Mackinnon, D. F., Potash, J. B., Simpson, S. G., McMahon, F. J., Depaulo, J. R. & McInnis, M. G., 2001, In : European Journal of Human Genetics. 9, 12, p. 922-930 9 p.

Research output: Contribution to journalArticle

The familial aggregation of psychotic symptoms in bipolar disorder pedigrees

Potash, J. B., Willour, V. L., Chiu, Y. F., Simpson, S. G., Mackinnon, D. F., Pearlson, G. D., Raymond Depaulo J., J. & McInnis, M. G., Aug 16 2001, In : American Journal of Psychiatry. 158, 8, p. 1258-1264 7 p.

Research output: Contribution to journalArticle

2002

Comorbid bipolar disorder and panic disorder in families with a high prevalence of bipolar disorder

MacKinnon, D. F., Zandi, P. P., Cooper, J., Potash, J. B., Simpson, S. G., Gershon, E., Nurnberger, J., Reich, T. & DePaulo, J. R., Jan 1 2002, In : American Journal of Psychiatry. 159, 1, p. 30-35 6 p.

Research output: Contribution to journalArticle

Diagnostic reliability of bipolar II disorder

Simpson, S. G., McMahon, F. J., McInnis, M. G., Mackinnon, D. F., Edwin, D., Folstein, S. E. & Depaulo, J. R., 2002, In : Archives of General Psychiatry. 59, 8, p. 736-740 5 p.

Research output: Contribution to journalArticle

Mania or anxiety disorders linked to panic disorder [7] (multiple letters)

Parvin, M. M., Swartz, C. M. & MacKinnon, D. F., Dec 1 2002, In : American Journal of Psychiatry. 159, 12, p. 2115-2116 2 p.

Research output: Contribution to journalLetter

2003

Association of rapid mood switching with panic disorder and familial panic risk in familial bipolar disorder

Mackinnon, D. F., Zandi, P. P., Gershon, E. S., Nurnberger, J. I. & Depaulo, J. R., Sep 2003, In : American Journal of Psychiatry. 160, 9, p. 1696-1698 3 p.

Research output: Contribution to journalArticle

Familial aggregation of psychotic symptoms in a replication set of 69 bipolar disorder pedigrees

Potash, J. B., Chiu, Y. F., Mackinnon, D. F., Miller, E. B., Simpson, S. G., McMahon, F. J., McInnis, M. G. & Depaulo, J. R., Jan 1 2003, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 116 B, 1, p. 90-97 8 p.

Research output: Contribution to journalArticle

Genetics of Recurrent Early-Onset Depression (GenRED): Design and preliminary clinical characteristics of a repository sample for genetic linkage studies

Levinson, D. F., Zubenko, G. S., Crowe, R. R., DePaulo, R. J., Scheftner, W. S., Weissman, M. M., Holmans, P., Zubenko, W. N., Boutelle, S., Murphy-Eberenz, K., MacKinnon, D., McInnis, M. G., Marta, D. H., Adams, P., Sassoon, S., Knowles, J. A., Thomas, J. & Chellis, J., May 15 2003, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 119 B, 1, p. 118-130 13 p.

Research output: Contribution to journalArticle

Genome scan of a second wave of NIMH genetics initiative bipolar pedigrees: Chromosomes 2, 11, 13, 14, and X

Zandi, P. P., Willour, V. L., Huo, Y., Chellis, J., Potash, J. B., MacKinnon, D. F., Simpson, S. G., McMahon, F. J., Gershon, E., Reich, T., Foroud, T., Nurnberger, J., DePaulo, J. R. & McInnis, M. G., May 15 2003, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 119 B, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: Chromosomes 4, 7, 9, 18, 19, 20, and 21

Willour, V. L., Zandi, P. P., Huo, Y., Diggs, T. L., Chellis, J. L., Mackinnon, D. F., Simpson, S. G., McMahon, F. J., Potash, J. B., Gershon, E. S., Reich, T., Foroud, T., Nurnberger, J. I., Depaulo, J. R. & McInnis, M. G., Aug 15 2003, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 121 B, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

Genomewide linkage analyses of bipolar disorder: A new sample of 250 pedigrees from the national institute of mental health genetics initiative

Dick, D. M., Foroud, T., Flury, L., Bowman, E. S., Miller, M. J., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Hahn, R., Widmark, C., McKinney, R., Sutton, L., Ballas, C., Grice, D., Berrettini, W. & 12 others, Byerley, W., Coryell, W., DePaulo, R., MacKinnon, D. F., Gershon, E. S., Kelsoe, J. R., McMahon, F. J., McInnis, M., Murphy, D. L., Reich, T., Scheftner, W. & Nurnberger, J. I., Jul 1 2003, In : American journal of human genetics. 73, 1, p. 107-114 8 p.

Research output: Contribution to journalArticle

Genome-wide scan and conditional analysis in bipolar disorder: Evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees

McInnis, M. G., Dick, D. M., Willour, V. L., Avramopoulos, D., MacKinnon, D. F., Simpson, S. G., Potash, J. B., Edenberg, H. J., Bowman, E. S., McMahon, F. J., Smiley, C., Chellis, J. L., Huo, Y., Diggs, T., Meyer, E. T., Miller, M., Matteini, A. T., Rau, N. L., DePaulo, J. R., Gershon, E. S. & 8 others, Badner, J. A., Rice, J. P., Goate, A. M., Detera-Wadleigh, S. D., Nurnberger, J. I., Reich, T., Zandi, P. P. & Foroud, T. M., Dec 1 2003, In : Biological psychiatry. 54, 11, p. 1265-1273 9 p.

Research output: Contribution to journalArticle

Genome-wide scan of bipolar disorder in 65 pedigrees: Supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12

McInnis, M. G., Lan, T. H., Willour, V. L., McMahon, F. J., Simpson, S. G., Addington, A. M., MacKinnon, D. F., Potash, J. B., Mahoney, A. T., Chellis, J., Huo, Y., Swift-Scanlan, T., Chen, H., Koskela, R., Colin Stine, O., Jamison, K. R., Holmans, P., Folstein, S. E., Ranade, K., Friddle, C. & 5 others, Botstein, D., Marr, T., Beaty, T. H., Zandi, P. & Raymond DePaulo, J., Jun 25 2003, In : Molecular psychiatry. 8, 3, p. 288-298 11 p.

Research output: Contribution to journalArticle

Rapid switching of mood in families with multiple cases of bipolar disorder

MacKinnon, D. F., Zandi, P. P., Gershon, E., Nurnberger, J. I., Reich, T. & DePaulo, J. R., Sep 1 2003, In : Archives of general psychiatry. 60, 9, p. 921-928 8 p.

Research output: Contribution to journalArticle

Suggestive linkage to chromosomal regions 13q31 and 22q12 in families with psychotic bipolar disorder

Potash, J. B., Zandi, P. P., Willour, V. L., Lan, T. H., Huo, Y., Avramopoulos, D., Shugart, Y. Y., MacKinnon, D. F., Simpson, S. G., McMahon, F. J., DePaulo, J. R. & McInnis, M. G., Apr 2003, In : American Journal of Psychiatry. 160, 4, p. 680-686 7 p.

Research output: Contribution to journalArticle

Trapping and sequence analysis of 1138 putative exons from human chromosome 18

Chen, H., Wang, N., Huo, Y., Sklar, P., MacKinnon, D. F., Potash, J. B., McMahon, F. J., Antonarakis, S. E., DePaulo, J. R., Ross, C. A. & McInnis, M. G., Aug 4 2003, In : Molecular psychiatry. 8, 6, p. 619-623 5 p.

Research output: Contribution to journalArticle

2004

Genomewide significant linkage to recurrent, early-onset major depressive disorder on chromosome 15q

Holmans, P., Zubenko, G. S., Crowe, R. R., DePaulo, J. R., Scheftner, W. A., Weissman, M. M., Zubenko, W. N., Boutelle, S., Murphy-Eberenz, K., MacKinnon, D., McInnis, M. G., Marta, D. H., Adams, P., Knowles, J. A., Gladis, M., Thomas, J., Chellis, J., Miller, E. & Levinson, D. F., Jun 2004, In : American journal of human genetics. 74, 6, p. 1154-1167 14 p.

Research output: Contribution to journalArticle

Linkage of bipolar affective disorder on chromosome 8q24: Follow-up and parametric analysis

Avramopoulos, D., Willour, V. L., Zandi, P. P., Huo, Y., MacKinnon, D. F., Potash, J. B., DePaulo, J. R. & McInnis, M. G., Mar 16 2004, In : Molecular psychiatry. 9, 2, p. 191-196 6 p.

Research output: Contribution to journalArticle

Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees

Schulze, T. G., Buervenich, S., Badner, J. A., Steele, C. J. M., Detera-Wadleigh, S. D., Dick, D., Foroud, T., Cox, N. J., Mackinnon, D. F., Potash, J. B., Berrettini, W. H., Byerley, W., Coryell, W., Depaulo, J. R., Gershon, E. S., Kelsoe, J. R., McInnis, M. G., Murphy, D. L., Reich, T., Scheftner, W. & 2 others, Nurnberger, J. I. & McMahon, F. J., Jul 1 2004, In : Biological Psychiatry. 56, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

2005

Assessment of the effect of age at onset on linkage to bipolar disorder: Evidence on chromosomes 18p and 21q

Lin, P. I., McInnis, M. G., Potash, J. B., Willour, V. L., MacKinnon, D. F., Miao, K., DePaulo, J. R. & Zandi, P. P., Oct 2005, In : American journal of human genetics. 77, 4, p. 545-555 11 p.

Research output: Contribution to journalArticle

Rapid mood switching and suicidality in familial bipolar disorder

MacKinnon, D. F., Potash, J. B., McMahon, F. J., Simpson, S. G., DePaulo, J. R., Nurnberger, J., McInnis, M., Murphy, D. L., Scheftner, W., Coryell, W., Berrettini, W., Byerley, W., Kelsoe, J., Gershon, E., Reich, T., Rice, J. & Zandi, P. P., Oct 1 2005, In : Bipolar Disorders. 7, 5, p. 441-448 8 p.

Research output: Contribution to journalArticle

2006

Clinical correlates and familial aggregation of age at onset in bipolar disorder

Lin, P. I., McInnis, M. G., Potash, J. B., Willour, V., Mackinnon, D. F., Depaulo, J. R. & Zandi, P. P., Feb 2006, In : American Journal of Psychiatry. 163, 2, p. 240-246 7 p.

Research output: Contribution to journalArticle

Familial aggregation of illness chronicity in recurrent, early-onset major depression pedigrees

Mondimore, F. M., Zandi, P. P., MacKinnon, D. F., McInnis, M. G., Miller, E. B., Crowe, R. P., Scheftner, W. A., Marta, D. H., Weissman, M. M., Levinson, D. F., Murphy-Ebenez, K. P., DePaulo, J. R. & Potash, J. B., Sep 2006, In : American Journal of Psychiatry. 163, 9, p. 1554-1560 7 p.

Research output: Contribution to journalArticle

Panic comorbidity with bipolar disorder: What is the manic-panic connection?

MacKinnon, D. F. & Zamoiski, R., Dec 1 2006, In : Bipolar Disorders. 8, 6, p. 648-664 17 p.

Research output: Contribution to journalArticle

2007

A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity

Mondimore, F. M., Zandi, P. P., MacKinnon, D. F., McInnis, M. G., Miller, E. B., Schweizer, B., Crowe, R. P., Scheftner, W. A., Weissman, M. M., Levinson, D. F., DePaulo, J. R. & Potash, J. B., Jun 1 2007, In : Journal of Affective Disorders. 100, 1-3, p. 171-177 7 p.

Research output: Contribution to journalArticle

Affective Disorders

MacKinnon, D. F., Jan 1 2007, Encyclopedia of Stress. Elsevier Inc., p. 78-84 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Attempted Suicide in Bipolar Disorder Pedigrees: Evidence for Linkage to 2p12

Willour, V. L., Zandi, P. P., Badner, J. A., Steele, J., Miao, K., Lopez, V., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., McInnis, M. G., Miller, E. B., DePaulo, J. R., Gershon, E. S., McMahon, F. J. & Potash, J. B., Mar 1 2007, In : Biological psychiatry. 61, 5, p. 725-727 3 p.

Research output: Contribution to journalArticle