Dean F Mackinnon

Associate Professor

1989 …2019
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Research Output 1989 2019

2019

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Jan 1 2019, In : Nature genetics.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Phenotype
Sample Size
Meta-Analysis
Autism Spectrum Disorder

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2019, In : Nature communications. 10, 1, 2548.

Research output: Contribution to journalArticle

Open Access
methylation
DNA Methylation
Fetal Blood
blood
Blood
2018

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Jan 1 2018, (Accepted/In press) In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Research output: Contribution to journalArticle

Major Depressive Disorder
Anisotropy
Genome
Radiation
Diffusion Tensor Imaging
Medical Students
Substance-Related Disorders
medical student
optimism
Stereotyping

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2018, In : Biological Psychiatry. 84, 2, p. 138-147 10 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Genomics
Psychiatry
Meta-Analysis
Depression

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 196 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., Mackinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., May 1 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Depression
Schizophrenia
Major Depressive Disorder
Suicide

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2018, In : PLoS One. 13, 12, e0209160.

Research output: Contribution to journalArticle

Major Depressive Disorder
Proxy
Genes
Genome
genome
2017

Genetic association of major depression with a typical features and obesity-related immunometabolic dysregulations

CHARGE InflammationWorking Group and the Major Depressive DisorderWorking Group of the Psychiatric Genomics Consortium, Dec 1 2017, In : JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journalArticle

Appetite
Major Depressive Disorder
Obesity
Depression
Weights and Measures
2016

The "hard" and "soft" phenotypic boundaries of bipolar disorder

Mackinnon, D. F., Aug 1 2016, In : Psychiatric Times. 33, 8

Research output: Contribution to journalArticle

Bipolar Disorder
2015

Distinguishing bipolar from unipolar depression: The importance of clinical symptoms and illness features

Walsh, A., Liebers, D., Pirooznia, M., Jancic, D., Mackinnon, D. F., Mondimore, F. M., Schweizer, B. W., Potash, J. B., Zandi, P. P. & Goes, F. S., May 4 2015, In : Psychological Medicine. 45, 11, p. 2437-2446 10 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Depressive Disorder
Bipolar Disorder
Depression
ROC Curve

Test-retest reliability of a new questionnaire for the retrospective assessment of long-term lithium use in bipolar disorder

Tighe, S. K., Ritchey, M., Schweizer, B. W., Goes, F. S., Mackinnon, D. F., Mondimore, F. M., Depaulo, J. R., McMahon, F. J., Schulze, T. G., Zandi, P. P. & Potash, J. B., Feb 1 2015, In : Journal of Affective Disorders. 174, p. 589-593 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Lithium
Reproducibility of Results
Research Subjects
Surveys and Questionnaires
2014

Delirium presenting as mania in a patient with end-stage COPD

Wilkinson, S. T., Chang, S. B., Foley, T., Lipsey, J. R. & Mackinnon, D. F., 2014, In : American Journal of Psychiatry. 171, 8, p. 821-824 4 p.

Research output: Contribution to journalArticle

Delirium
Mania
Bipolar Disorder

Type I interferon signaling genes in recurrent major depression: Increased expression detected by whole-blood RNA sequencing

Mostafavi, S., Battle, A., Zhu, X., Potash, J. B., Weissman, M. M., Shi, J., Beckman, K., Haudenschild, C., Mccormick, C., Mei, R., Gameroff, M. J., Gindes, H., Adams, P., Goes, F. S., Mondimore, F. M., Mackinnon, D. F., Notes, L., Schweizer, B. W., Furman, D., Montgomery, S. B. & 3 others, Urban, A. E., Koller, D. & Levinson, D. F., Dec 11 2014, In : Molecular Psychiatry. 19, 12, p. 1267-1274 8 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Interferon Type I
Major Depressive Disorder
Depression
Genes
2013

Posttraumatic stress disorder increases risk for suicide attempt in adults with recurrent major depression

Stevens, D., Wilcox, H., Mackinnon, D. F., Mondimore, F. M., Schweizer, B. W., Jancic, D., Coryell, W. H., Weissman, M. M., Levinson, D. F. & Potash, J. B., Oct 2013, In : Depression and Anxiety. 30, 10, p. 940-946 7 p.

Research output: Contribution to journalArticle

Post-Traumatic Stress Disorders
Suicide
Depression
Major Depressive Disorder
Attempted Suicide
2012
Medical Students
Substance-Related Disorders
Teaching
Referral and Consultation
Medical Schools

A genome-wide association study of attempted suicide

Willour, V. L., Seifuddin, F., Mahon, P. B., Jancic, D., Pirooznia, M., Steele, J., Schweizer, B. W., Goes, F. S., Mondimore, F. M., Mackinnon, D. F., Perlis, R. H., Lee, P. H., Huang, J., Kelsoe, J. R., Shilling, P. D., Rietschel, M., Nöthen, M., Cichon, S., Gurling, H., Purcell, S. & 7 others, Smoller, J. W., Craddock, N., Depaulo, J. R., Schulze, T. G., McMahon, F. J., Zandi, P. P. & Potash, J. B., Apr 2012, In : Molecular Psychiatry. 17, 4, p. 433-444 12 p.

Research output: Contribution to journalArticle

Attempted Suicide
Genome-Wide Association Study
Acid Phosphatase
Suicide
Single Nucleotide Polymorphism

Association study of serotonin pathway genes in attempted suicide

Judy, J. T., Seifuddin, F., Mahon, P. B., Huo, Y., Goes, F. S., Jancic, D., Schweizer, B. W., Mondimore, F. M., Mackinnon, D. F., Depaulo, J. R., Gershon, E. S., Mcmahon, F. J., Cutler, D. J., Zandi, P. P., Potash, J. B. & Willour, V. L., Jan 2012, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 159 B, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

Attempted Suicide
Serotonin
Genes
Single Nucleotide Polymorphism
Haplotypes
Panic Disorder
Obsessive-Compulsive Disorder
Anxiety Disorders
Bipolar Disorder
Major Depressive Disorder
2011

Genetic association of bipolar disorder with the β3 nicotinic receptor subunit gene

Hartz, S. M., Lin, P., Edenberg, H. J., Xuei, X., Rochberg, N., Saccone, S., Berrettini, W., Nelson, E., Nurnberger, J., Bierut, L. J., Rice, J. P., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T. & 42 others, Smiley, C., Foroud, T., Flury, L., Dick, D. M., Reich, T., Goate, A., McInnis, M., Depaulo, J. R., Mackinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Byerley, W., Vinogradov, S., Coryell, W., Crowe, R., Gershon, E., Badner, J., McMahon, F., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F. J., Kassem, L., Detera-Wadleigh, S., Austin, L., Murphy, D. L., Lawson, W. B., Nwulia, E. & Hipolito, M., Apr 2011, In : Psychiatric Genetics. 21, 2, p. 77-84 8 p.

Research output: Contribution to journalArticle

Nicotinic Receptors
Tobacco Use Disorder
Bipolar Disorder
Genes
Single Nucleotide Polymorphism
psychiatry
mental illness
mood
disability
self-destruction
2010

Affective Disorders

Mackinnon, D. F., 2010, Encyclopedia of Stress. Elsevier Inc., p. 78-84 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mood Disorders
Grief
Personality

An investigation of candidate regions for association with bipolar disorder

NIMH Genetics Initiative Bipolar Disorder Consortium, Oct 1 2010, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 7, p. 1292-1297 6 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 6
Adenosine Triphosphatases
Case-Control Studies

Sex-specific association of the reelin gene with bipolar disorder

Goes, F. S., Willour, V. L., Zandi, P. P., Belmonte, P. L., Mackinnon, D. F., Mondimore, F. M., Schweizer, B. W., Depaulo, J. R., Gershon, E. S., McMahon, F. J. & Potash, J. B., Mar 2010, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 153, 2, p. 549-553 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Genes
Schizophrenia
Alleles
Neuronal Plasticity
2009

Carbon dioxide induces erratic respiratory responses in bipolar disorder

Mackinnon, D. F., Craighead, B. & Lorenz, L., Jan 2009, In : Journal of Affective Disorders. 112, 1-3, p. 193-200 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Carbon Dioxide
Panic
Air
Anxiety

Family-based association of FKBP5 in bipolar disorder

Willour, V. L., Chen, H., Toolan, J., Belmonte, P., Cutler, D. J., Goes, F. S., Zandi, P. P., Lee, R. S., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., DePaulo, J. R., Gershon, E. S., McMahon, F. J., Potash, J. B., McMahon, F., Steele, J., Pearl, J., Kassem, L., Lopez, V. & 64 others, Potash, J., MacKinnon, D., Miller, E., Toolan, J., Zandi, P., Schulze, T., Nwulia, E., Simpson, S., Nurnberger, J., Miller, M., Bowman, E., Reich, T., Goate, A., Rice, J., DePaulo, J. R., Stine, C., Gershon, E., Kazuba, D., Maxwell, E., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Bierut, L., McInnis, M., MacKinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Badner, J., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F. J., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Mar 2009, In : Molecular Psychiatry. 14, 3, p. 261-268 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Single Nucleotide Polymorphism
Genetic Models
Glucocorticoid Receptors
Antidepressive Agents

Family-based association of YWHAH in psychotic bipolar disorder

Grover, D., Verma, R., Goes, F. S., Belmonte Mahon, P. L., Gershon, E. S., McMahon, F. J., Potash, J. B., McMahon, F. J., Steele, J., Pearl, J., Kassem, L., Lopez, V., Schulze, T., Potash, J., MacKinnon, D., Miller, E., Toolan, J., Zandi, P., Simpson, S., Nurnberger, J. & 64 others, Miller, M., Bowman, E., Reich, T., Goate, A., Rice, J., DePaulo, J. R., Simpson, S., Stine, C., Gershon, E., Kazuba, D., Maxwell, E., Nurnberger, J., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Rice, J., Reich, T., Goate, A., Bierut, L., McInnis, M., DePaulo, J. R., MacKinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Gershon, E., Badner, J., McMahon, F., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F., Kassem, L., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Oct 5 2009, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 150, 7, p. 977-983 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Psychotic Disorders
Schizophrenia
Single Nucleotide Polymorphism
Chromosome Disorders

Family-based association study of neuregulin 1 with psychotic bipolar disorder

Goes, F. S., Willour, V. L., Zandi, P. P., Belmonte, P. L., Mackinnon, D. F., Mondimore, F. M., Schweizer, B. W., Gershon, E. S., McMahon, F. J. & Potash, J. B., Jul 5 2009, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 150, 5, p. 693-702 10 p.

Research output: Contribution to journalArticle

Neuregulin-1
Bipolar Disorder
Psychotic Disorders
Haplotypes
Single Nucleotide Polymorphism

Genome-wide linkage and follow-up association study of postpartum mood symptoms

Mahon, P. B., Payne, J., Mackinnon, D. F., Mondimore, F. M., Goes, F. S., Schweizer, B. W., Jancic, D., Coryell, W. H., Holmans, P. A., Shi, J., Zandi, P. P., Potash, J. B., Weissman, M. M., Levinson, D. F., DePaulo, J. R., Zandi, P. P., Depaulo, J. R., Kelsoe, J. R., Greenwood, T. A., Nievergelt, C. & 22 others, Schork, N., Smith, E. N., Bloss, C., Nurnberger, J., Edenberg, H. J., Foroud, T., Gershon, E., Liu, C., Badner, J. A., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F., Schulze, T. G., Berrettini, W., McInnis, M. G., Zöllner, S., Craig, D. & Avramopoulos, D., Nov 1 2009, In : American Journal of Psychiatry. 166, 11, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

Postpartum Period
Genome
Chromosomes
Mood Disorders
Single Nucleotide Polymorphism

Premenstrual mood symptoms: Study of familiality and personality correlates in mood disorder pedigrees

Payne, J. L., Klein, S. R., Zamoiski, R. B., Zandi, P. P., Bienvenu, O. J., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., Swartz, K. L., Crowe, R. P., Scheftner, W. A., Weissman, M. M., Levinson, D. F., Depaulo, J. R. & Potash, J. B., Feb 2009, In : Archives of Women's Mental Health. 12, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Pedigree
Mood Disorders
Personality
Bipolar Disorder
Major Depressive Disorder
2008

Association study of Wnt signaling pathway genes in bipolar disorder

Zandi, P. P., Belmonte, P. L., Willour, V. L., Goes, F. S., Badner, J. A., Simpson, S. G., Gershon, E. S., McMahon, F. J., Depaulo, J. R., Potash, J. B., Steele, J., Pearl, J., Kassem, L., Lopez, V., Mackinnon, D. F., Miller, E., Toolan, J., Schulze, T., Byerley, W., Coryell, W. & 3 others, Kelsoe, J., Rice, J. & Nurnberger, J., Jul 2008, In : Archives of General Psychiatry. 65, 7, p. 785-793 9 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Bipolar Disorder
Single Nucleotide Polymorphism
Genes
Public Health Schools

Bipolar disorder as maladaptive arousal

Mackinnon, D. F., May 2008, In : Annals of the New York Academy of Sciences. 1129, p. 185-189 5 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Arousal
Titration
Bipolar Disorder
Plasticity

Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder

Liu, L., Foroud, T., Xuei, X., Berrettini, W., Byerley, W., Coryell, W., El-Mallakh, R., Gershon, E. S., Kelsoe, J. R., Lawson, W. B., Mackinnon, D. F., McInnis, M., McMahon, F. J., Murphy, D. L., Rice, J., Scheftner, W., Zandi, P. P., Lohoff, F. W., Niculescu, A. B., Meyer, E. T. & 2 others, Edenberg, H. J. & Nurnberger, J. I., Dec 2008, In : Psychiatric Genetics. 18, 6, p. 267-274 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Bipolar Disorder
Single Nucleotide Polymorphism
Genes
Mood Disorders

Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees

Payne, J., Mackinnon, D. F., Mondimore, F. M., Mcinnis, M. G., Schweizer, B. W., Zamoiski, R. B., Mcmahon, F. J., Nurnberger, J. I., Rice, J. P., Scheftner, W., Coryell, W., Berrettini, W. H., Kelsoe, J. R., Byerley, W., Gershon, E. S., Depaulo, J. R. & Potash, J. B., Feb 2008, In : Bipolar Disorders. 10, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

Pedigree
Bipolar Disorder
Postpartum Period
Interviews
Depression

Rapid switching of mood in families with familial bipolar disorder

Nwulia, E. A., Zandi, P. P., McInnis, M. G., Depaulo, J. R. & Mackinnon, D. F., Aug 2008, In : Bipolar Disorders. 10, 5, p. 597-606 10 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Comorbidity
Anxiety
Odds Ratio
Confidence Intervals
2007

A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity

Mondimore, F. M., Zandi, P. P., Mackinnon, D. F., McInnis, M. G., Miller, E. B., Schweizer, B. W., Crowe, R. P., Scheftner, W. A., Weissman, M. M., Levinson, D. F., Depaulo, J. R. & Potash, J. B., Jun 2007, In : Journal of Affective Disorders. 100, 1-3, p. 171-177 7 p.

Research output: Contribution to journalArticle

Dysthymic Disorder
Pedigree
Diagnostic and Statistical Manual of Mental Disorders
Depression
Cluster Analysis

Attempted Suicide in Bipolar Disorder Pedigrees: Evidence for Linkage to 2p12

Willour, V. L., Zandi, P. P., Badner, J. A., Steele, J., Miao, K., Lopez, V., Mackinnon, D. F., Mondimore, F. M., Schweizer, B. W., McInnis, M. G., Miller, E. B., Depaulo, J. R., Gershon, E. S., McMahon, F. J. & Potash, J. B., Mar 1 2007, In : Biological Psychiatry. 61, 5, p. 725-727 3 p.

Research output: Contribution to journalArticle

Attempted Suicide
Pedigree
Bipolar Disorder
Chromosomes, Human, Pair 2
Information Storage and Retrieval

Carbon dioxide provocation of anxiety and respiratory response in bipolar disorder

Mackinnon, D. F., Craighead, B. & Hoehn-Saric, R., Apr 2007, In : Journal of Affective Disorders. 99, 1-3, p. 45-49 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Carbon Dioxide
Panic
Panic Disorder
Anxiety

Comorbidity of bipolar and panic disorders and its consequences

Mackinnon, D. F., Mar 2007, In : Psychiatric Times. 24, 3, p. 37-38 2 p.

Research output: Contribution to journalArticle

Panic Disorder
Bipolar Disorder
Comorbidity

Genetics of comorbid mood disorder and alcohol dependence

Nurnberger, J. I., Kuperman, S., Flury-Wetherill, L., Meyer, E. T., Lawson, W. B. & Mackinnon, D. F., Mar 22 2007, In : Journal of Dual Diagnosis. 3, 2, p. 31-46 16 p.

Research output: Contribution to journalArticle

Mood Disorders
Alcoholism
Bipolar Disorder
Genetic Linkage
Depression

Genetics of recurrent early-onset major depression (GenRED): Final genome scan report

Holmans, P., Weissman, M. M., Zubenko, G. S., Scheftner, W. A., Crowe, R. R., Depaulo, J. R., Knowles, J. A., Zubenko, W. N., Murphy-Eberenz, K., Marta, D. H., Boutelle, S., McInnis, M. G., Adams, P., Gladis, M., Steele, J., Miller, E. B., Potash, J. B., Mackinnon, D. F. & Levinson, D. F., Feb 2007, In : American Journal of Psychiatry. 164, 2, p. 248-258 11 p.

Research output: Contribution to journalArticle

Genome
Depression
Chromosomes
Major Depressive Disorder
Genetic Markers

Genome-wide linkage scan of 98 bipolar pedigrees and analysis of clinical covariates

Zandi, P. P., Badner, J. A., Steele, J., Willour, V. L., Miao, K., Mackinnon, D. F., Mondimore, F. M., Schweizer, B. W., McInnis, M. G., Depaulo, J. R., Gershon, E., McMahon, F. J. & Potash, J. B., Jul 23 2007, In : Molecular Psychiatry. 12, 7, p. 630-639 10 p.

Research output: Contribution to journalArticle

Pedigree
Bipolar Disorder
Genome
Age of Onset
Inborn Genetic Diseases

Genome-wide scan of bipolar II disorder

Nwulia, E. A., Miao, K., Zandi, P. P., Mackinnon, D. F., Depaulo, J. R. & Mcinnis, M. G., Sep 2007, In : Bipolar Disorders. 9, 6, p. 580-588 9 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Genome
Pedigree
Phenotype
Chromosomes

Mood-incongruent psychotic features in bipolar disorder: Familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33

Goes, F. S., Zandi, P. P., Miao, K., McMahon, F. J., Steele, J., Willour, V. L., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., Nurnberger, J. I., Rice, J. P., Scheftner, W., Coryell, W., Berrettini, W. H., Kelsoe, J. R., Byerley, W., Murphy, D. L., Gershon, E. S., DePaulo, J. R., McInnis, M. G. & 1 others, Potash, J. B., Feb 2007, In : American Journal of Psychiatry. 164, 2, p. 236-247 12 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Schizophrenia
Genome
National Institute of Mental Health (U.S.)
Attempted Suicide

Psychotic features in bipolar and unipolar depression

Goes, F. S., Sadler, B., Toolan, J., Zamoiski, R. D., Mondimore, F. M., Mackinnon, D. F., Schweizer, B. W., Depaulo, J. R. & Potash, J. B., Dec 2007, In : Bipolar Disorders. 9, 8, p. 901-906 6 p.

Research output: Contribution to journalArticle

Depressive Disorder
Bipolar Disorder
Mood Disorders
Depression
Major Depressive Disorder
Serotonin Uptake Inhibitors

Reproductive cycle-associated mood symptoms in women with major depression and bipolar disorder

Payne, J., Roy, P. S., Murphy-Eberenz, K., Weismann, M. M., Swartz, K. L., McInnis, M. G., Nwulia, E., Mondimore, F. M., Mackinnon, D. F., Miller, E. B., Nurnberger, J. I., Levinson, D. F., Depaulo, J. R. & Potash, J. B., Apr 2007, In : Journal of Affective Disorders. 99, 1-3, p. 221-229 9 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Depression
Mood Disorders
Odds Ratio
Perimenopause

SNP fine mapping of chromosome 8q24 in bipolar disorder

Zandi, P. P., Avramopoulos, D., Willour, V. L., Huo, Y., Miao, K., Mackinnon, D. F., McInnis, M. G., Potash, J. B. & Depaulo, J. R., Jul 5 2007, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 144, 5, p. 625-630 6 p.

Research output: Contribution to journalArticle

Chromosome Mapping
Bipolar Disorder
Single Nucleotide Polymorphism
Nuclear Family
Genes

The bipolar disorder phenome database: A resource for genetic studies

Potash, J. B., Toolan, J., Steele, J., Miller, E. B., Pearl, J., Zandi, P. P., Schulze, T. G., Kassem, L., Simpson, S. G., Lopez, V., MacKinnon, D. F. & McMahon, F. J., Aug 2007, In : American Journal of Psychiatry. 164, 8, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Genetic Linkage
Databases
National Institute of Mental Health (U.S.)
Genetic Association Studies
2006
Borderline Personality Disorder
Bipolar Disorder
Personality
Anticonvulsants
Personality Development

Clinical correlates and familial aggregation of age at onset in bipolar disorder

Lin, P. I., McInnis, M. G., Potash, J. B., Willour, V., Mackinnon, D. F., Depaulo, J. R. & Zandi, P. P., Feb 2006, In : American Journal of Psychiatry. 163, 2, p. 240-246 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Age of Onset
Normal Distribution
Genetic Heterogeneity
Suicide