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David Sidransky

Professor

1991 …2018

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  • 3 Similar Profiles
Neoplasms Medicine & Life Sciences
Methylation Medicine & Life Sciences
Mutation Medicine & Life Sciences
Head and Neck Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Loss of Heterozygosity Medicine & Life Sciences
Tumor Suppressor Genes Medicine & Life Sciences
Microsatellite Repeats Medicine & Life Sciences

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Research Output 1991 2018

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

Ravi, R., Noonan, K. A., Pham, V., Bedi, R., Zhavoronkov, A., Ozerov, I. V., Makarev, E., Artemov, A. V., Wysocki, P. T., Mehra, R., Nimmagadda, S., Marchionni, L., Sidransky, D., Borrello, I. M., Izumchenko, E. & Bedi, A. Dec 1 2018 In : Nature Communications. 9, 1, 741

Research output: Contribution to journal › Article

beta factor
CTLA-4 Antigen
antibodies
Transforming Growth Factor beta
Immunotherapy

Growth of malignant non-CNS tumors alters brain metabolome

Kovalchuk, A., Nersisyan, L., Mandal, R., Wishart, D., Mancini, M., Sidransky, D., Kolb, B. & Kovalchuk, O. Feb 20 2018 In : Frontiers in Genetics. 9, FEB, 41

Research output: Contribution to journal › Article

Metabolome
Brain Neoplasms
Growth
Brain
Neoplasms

Growth of triple negative and progesterone positive breast cancer causes oxidative stress and down-regulates neuroprotective transcription factor NPAS4 and NPAS4-regulated genes in hippocampal tissues of tumorgraft mice - An aging connection

Kovalchuk, A., Ilnytskyy, Y., Rodriguez-Juarez, R., Katz, A., Sidransky, D., Kolb, B. & Kovalchuk, O. Mar 5 2018 In : Frontiers in Genetics. 9, MAR, 58

Research output: Contribution to journal › Article

Brain Neoplasms
Progesterone
Oxidative Stress
Transcription Factors
Down-Regulation

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program

Pirini, F., Rodriguez-Torres, S., Ayandibu, B. G., Orera-Clemente, M., Gonzalez-De La Vega, A., Lawson, F., Thorpe, R. J., Sidransky, D. & Guerrero-Preston, R. Jan 1 2018 In : Molecular Medicine Reports. 17, 1, p. 1699-1709 11 p.

Research output: Contribution to journal › Article

Weight Reduction Programs
DNA Methylation
Weight Loss
Nucleotides
Lipid Metabolism

Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells

Rajagopalan, P., Nanjappa, V., Patel, K., Jain, A. P., Mangalaparthi, K. K., Patil, A. H., Nair, B., Mathur, P. P., Keshava Prasad, T. S., Califano, J. A., Sidransky, D., Gowda, H. & Chatterjee, A. Feb 26 2018 (Accepted/In press) In : Journal of Cell Communication and Signaling. p. 1-13 13 p.

Research output: Contribution to journal › Article

Smoke
Tobacco Products
Cells
Head and Neck Neoplasms
Keratinocytes