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David Sidransky

Professor

1991 …2018
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Research Output 1991 2018

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

Ravi, R., Noonan, K. A., Pham, V., Bedi, R., Zhavoronkov, A., Ozerov, I. V., Makarev, E., Artemov, A. V., Wysocki, P. T., Mehra, R., Nimmagadda, S., Marchionni, L., Sidransky, D., Borrello, I. M., Izumchenko, E. & Bedi, A., Dec 1 2018, In : Nature Communications. 9, 1, 741

Research output: Contribution to journal › Article

beta factor
CTLA-4 Antigen
antibodies
Transforming Growth Factor beta
Immunotherapy

Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes

Bhat, M. Y., Advani, J., Rajagopalan, P., Patel, K., Nanjappa, V., Solanki, H. S., Patil, A. H., Bhat, F. A., Mathur, P. P., Nair, B., Prasad, T. S. K., Califano, J. A., Sidransky, D., Gowda, H. & Chatterjee, A., Dec 1 2018, In : Scientific Reports. 8, 1, 7040

Research output: Contribution to journal › Article

Smokeless Tobacco
MicroRNAs
Keratinocytes
Smoke
Tobacco Products

Growth of malignant non-CNS tumors alters brain metabolome

Kovalchuk, A., Nersisyan, L., Mandal, R., Wishart, D., Mancini, M., Sidransky, D., Kolb, B. & Kovalchuk, O., Feb 20 2018, In : Frontiers in Genetics. 9, FEB, 41

Research output: Contribution to journal › Article

Metabolome
Brain Neoplasms
Growth
Brain
Neoplasms

Growth of triple negative and progesterone positive breast cancer causes oxidative stress and down-regulates neuroprotective transcription factor NPAS4 and NPAS4-regulated genes in hippocampal tissues of tumorgraft mice - An aging connection

Kovalchuk, A., Ilnytskyy, Y., Rodriguez-Juarez, R., Katz, A., Sidransky, D., Kolb, B. & Kovalchuk, O., Mar 5 2018, In : Frontiers in Genetics. 9, MAR, 58

Research output: Contribution to journal › Article

Brain Neoplasms
Progesterone
Oxidative Stress
Transcription Factors
Down-Regulation

Identification of potential biomarkers of head and neck squamous cell carcinoma using iTRAQ based quantitative proteomic approach

Babu, N., Mohan, S., Nanjappa, V., Chavan, S., Advani, J., Khan, A. A., Renuse, S., Radhakrishnan, A., Prasad, T. S. K., Kumar, R. V., Ray, J. G., Biswas, M., Thiyagarajan, S., Califano, J. A., Sidransky, D., Gowda, H. & Chatterjee, A., Aug 1 2018, In : Data in Brief. 19, p. 1124-1130 7 p.

Research output: Contribution to journal › Article

Proteomics
Biomarkers
Cell Line
Proteins
Carcinoma, squamous cell of head and neck