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David A Kass

Professor

1976 …2019
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Heart Failure Medicine & Life Sciences
Cardiac Resynchronization Therapy Medicine & Life Sciences
Pressure Medicine & Life Sciences
Blood Pressure Medicine & Life Sciences
Type 5 Cyclic Nucleotide Phosphodiesterases Medicine & Life Sciences
Cardiac Myocytes Medicine & Life Sciences
Muscle Cells Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences

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Research Output 1976 2019

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury

Barefield, D. Y., McNamara, J. W., Lynch, T. L., Kuster, D. W. D., Govindan, S., Haar, L., Wang, Y., Taylor, E. N., Lorenz, J. N., Nieman, M. L., Zhu, G., Luther, P. K., Varró, A., Dobrev, D., Ai, X., Janssen, P. M. L., Kass, D. A., Jones, W. K., Gilbert, R. J. & Sadayappan, S., Apr 1 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 236-246 11 p.

Research output: Contribution to journal › Article

Open Access
Cardiac Myosins
Calpain
Reperfusion Injury
Proteolysis
Phosphorylation

Chronic Atrial and Ventricular Pacing in the Mouse

Ståhlberg, M., Nakagawa, R., Bedja, D., Zhu, G., Lin, B. L., Saberi, A., Lee, D. & Kass, D. A., Feb 1 2019, In : Circulation. Heart failure. 12, 2, p. e005655

Research output: Contribution to journal › Article

Heart Ventricles
Heart Atria
Reperfusion Injury
Muscle Cells
Reperfusion

Fresh evidence overturns the identification of a factor involved in blood-vessel dilation

Kass, D. A., Feb 1 2019, In : Nature. 566, 7745, p. 462-464 3 p.

Research output: Contribution to journal › Comment/debate

Open Access
Singlet Oxygen
Biochemistry
Blood Vessels
Dilatation
Oxygen

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease

Lin, B. L., Matera, D., Doerner, J. F., Zheng, N., Del Camino, D., Mishra, S., Bian, H., Zeveleva, S., Zhen, X., Blair, N. T., Chong, J. A., Hessler, D. P., Bedja, D., Zhu, G., Muller, G. K., Ranek, M., Pantages, L., McFarland, M., Netherton, M. R., Berry, A. & 10 others, Wong, D., Rast, G., Qian, H. S., Weldon, S. M., Kuo, J. J., Sauer, A., Sarko, C., Moran, M. M., Kass, D. A. & Pullen, S. S., May 14 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10156-10161 6 p.

Research output: Contribution to journal › Article

Heart Diseases
Fibrosis
Kidney
NFATC Transcription Factors
Gene Expression

Leveraging Signaling Pathways to Treat Heart Failure With Reduced Ejection Fraction

Pinilla-Vera, M., Hahn, V. S. & Kass, D. A., May 24 2019, In : Circulation research. 124, 11, p. 1618-1632 15 p.

Research output: Contribution to journal › Article

Open Access
Heart Failure
Treatment Failure
Cardiomyopathies
Cell Biology
Therapeutics