Darren Brian Foster

Assistant Professor

19952017
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Research Output 1995 2017

Cardiosphere-Derived Cells Demonstrate Metabolic Flexibility That Is Influenced by Adhesion Status

Afzal, J., Chan, A., Karakas, M. F., Woldemichael, K., Vakrou, S., Guan, Y., Rathmell, J., Wahl, R., Pomper, M., Foster, D. B., Aon, M. A., Tsui, B., O'Rourke, B. & Abraham, M. R., Oct 1 2017, In : JACC: Basic to Translational Science. 2, 5, p. 543-560 18 p.

Research output: Contribution to journalArticle

Glycolysis
Cell Adhesion
Adenosine Triphosphate
Phosphorylation
Glucose

Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death

Brian Foster, D., Liu, T., Kammers, K., O'Meally, R., Yang, N., Papanicolaou, K. N., Conover Talbot, C., Cole, R. N. & O'Rourke, B., Sep 2 2016, In : Journal of Proteome Research. 15, 9, p. 3009-3028 20 p.

Research output: Contribution to journalArticle

Sudden Cardiac Death
Guinea Pigs
Heart Failure
Hypertrophy
Proteome

Seeing the Forest for the Trees

O'Rourke, B., Liu, T. & Foster, D. B., Nov 11 2016, In : Circulation Research. 119, 11, p. 1170-1172 3 p.

Research output: Contribution to journalComment/debate

A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis

Wijnker, P. J. M., Li, Y., Zhang, P., Foster, D. B., dos Remedios, C., Van Eyk, J. E., Stienen, G. J. M., Murphy, A. M. & van der Velden, J., May 1 2015, In : Journal of Molecular and Cellular Cardiology. 82, p. 3-103 101 p.

Research output: Contribution to journalArticle

Troponin I
Calpain
Serine
Proteolysis
Phosphorylation

Cardiac troponin i Pro82Ser variant induces diastolic dysfunction, blunts β-adrenergic response, and impairs myofilament cooperativity

Ramirez-Correa, G. A., Frazier, A. H., Zhu, G., Zhang, P., Rappold, T., Kooij, V., Bedja, D., Snyder, G. A., Lugo-Fagundo, N. S., Hariharan, R., Li, Y., Shen, X., Gao, W. D., Cingolani, O. H., Takimoto, E., Foster, D. B. & Murphy, A. M., Jan 15 2015, In : Journal of Applied Physiology. 118, 2, p. 212-223 12 p.

Research output: Contribution to journalArticle

Troponin
Myofibrils
Adrenergic Agents
Transgenic Mice
Pressure