Research Output 2001 2017

  • 37 Article
  • 2 Review article
  • 1 Chapter
  • 1 Conference contribution
2017

Antigliadin antibodies (AGA IgG) are related to neurochemistry in schizophrenia

Rowland, L. M., Demyanovich, H. K., Wijtenburg, S. A., Eaton, W. W., Rodriguez, K., Gaston, F., Cihakova, D., Talor, M. V., Liu, F., McMahon, R. R., Hong, L. E. & Kelly, D. L. Jun 19 2017 In : Frontiers in Psychiatry. 8, JUN, 104

Research output: Research - peer-reviewArticle

Neurochemistry
Schizophrenia
Immunoglobulin G
Antibodies
Inositol

Cardiac autoimmunity: Myocarditis

Bracamonte-Baran, W. & Čiháková, D. 2017 Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 1003, p. 187-221 35 p. (Advances in Experimental Medicine and Biology; vol. 1003)

Research output: ResearchChapter

Myocarditis
Autoimmunity
Tissue
Dilated Cardiomyopathy
Myocardium

Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy

Diny, N. L., Baldeviano, G. C., Talor, M. V., Barin, J. G., Ong, S. F., Bedja, D., Hays, A. G., Gilotra, N. A., Coppens, I., Rose, N. R. & Čiháková, D. Apr 1 2017 In : Journal of Experimental Medicine. 214, 4, p. 943-957 15 p.

Research output: Research - peer-reviewArticle

Myocarditis
Dilated Cardiomyopathy
Eosinophils
Interleukin-4
Interleukin-5

Eosinophils in autoimmune diseases

Diny, N. L., Rose, N. R. & Čiháková, D. Apr 27 2017 In : Frontiers in Immunology. 8, APR, 484

Research output: Research - peer-reviewReview article

Eosinophils
Autoimmune Diseases
Asthma
Eosinophilic Esophagitis
Neuromyelitis Optica

Gliadin-related antibodies in schizophrenia

Čiháková, D., Eaton, W. W., Talor, M. V., Harkus, U. H., Demyanovich, H. K., Rodriguez, K., Feldman, S. & Kelly, D. L. 2017 (Accepted/In press) In : Schizophrenia Research.

Research output: Research - peer-reviewArticle

Natural killer cells in inflammatory heart disease

Ong, S. F., Rose, N. R. & Čiháková, D. Feb 1 2017 In : Clinical Immunology. 175, p. 26-33 8 p.

Research output: Research - peer-reviewReview article

Natural Killer Cells
Heart Diseases
Therapeutics
Inflammation
Natural Killer Cell Receptors

Regulation of autoimmune myocarditis by host responses to the microbiome

Barin, J. G., Talor, M. V., Diny, N. L., Ong, S. F., Schaub, J. A., Gebremariam, E., Bedja, D., Chen, G., Choi, H. S., Hou, X., Wu, L., Cardamone, A. B., Peterson, D. A., Rose, N. R. & Čiháková, D. Oct 1 2017 In : Experimental and Molecular Pathology. 103, 2, p. 141-152 12 p.

Research output: Research - peer-reviewArticle

Microbiota
Myocarditis
Heart Diseases
Disease Susceptibility
Chemotaxis
2016

Cannabidiol limits T cell–mediated chronic autoimmune myocarditis: Implications to autoimmune disorders and organ transplantation

Lee, W. S., Erdelyi, K., Matyas, C., Mukhopadhyay, P., Varga, Z. V., Liaudet, L., Haskó, G., Čiháková, D., Mechoulam, R. & Pacher, P. 2016 In : Molecular Medicine. 22, p. 136-146 11 p.

Research output: Research - peer-reviewArticle

Cannabidiol
Myocarditis
Organ Transplantation
T-Lymphocytes
Therapeutics

Cardiac antibody production to self-antigens in children and adolescents during and following the correction of severe diabetic ketoacidosis

Hoffman, W. H., Sharma, M., Cihakova, D., Talor, M. V., Rose, N. R., Mohanakumar, T. & Passmore, G. G. Feb 24 2016 (Accepted/In press) In : Autoimmunity. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Diabetic Cardiomyopathies
Diabetic Ketoacidosis
Autoantigens
Antibody Formation
Antibodies

Collaborative Interferon-γ and Interleukin-17 Signaling Protects the Oral Mucosa from Staphylococcus aureus

Barin, J. G., Talor, M. V., Schaub, J. A., Diny, N. L., Hou, X., Hoyer, M., Archer, N. K., Gebremariam, E. S., Davis, M. F., Miller, L. S., Rose, N. R. & Čiháková, D. Sep 1 2016 In : American Journal of Pathology. 186, 9, p. 2337-2352 16 p.

Research output: Research - peer-reviewArticle

Interleukin-17
Mouth Mucosa
Interferon-gamma
Staphylococcus aureus
Macrophages

Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart

Diny, N. L., Hou, X., Barin, J. G., Chen, G., Talor, M. V., Schaub, J., Russell, S. D., Klingel, K., Rose, N. R. & Čiháková, D. Dec 1 2016 In : European Journal of Immunology. 46, 12, p. 2749-2760 12 p.

Research output: Research - peer-reviewArticle

Myocarditis
Eosinophils
Fibroblasts
Macrophages
CCR3 Receptors

Pathogenic IL-23 signaling is required to initiate GM-CSF-driven autoimmune myocarditis in mice

Wu, L., Diny, N. L., Ong, S., Barin, J. G., Hou, X., Rose, N. R., Talor, M. V. & Čiháková, D. Mar 1 2016 In : European Journal of Immunology. 46, 3, p. 582-592 11 p.

Research output: Research - peer-reviewArticle

Interleukin-23
Myocarditis
Granulocyte-Macrophage Colony-Stimulating Factor
T-Lymphocytes
Virulence
2015

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

Hobbs, R. P., Depianto, D. J., Jacob, J. T., Han, M. C., Chung, B. M., Batazzi, A. S., Poll, B. G., Guo, Y., Han, J., Ong, S., Zheng, W., Taube, J. M., Ciháková, D., Wan, F. & Coulombe, P. A. Aug 30 2015 In : Nature Genetics. 47, 8, p. 933-938 6 p.

Research output: Research - peer-reviewArticle

Keratin-17
Regulator Genes
Keratins
Keratinocytes
Gene Expression

Natural killer cells limit cardiac inflammation and fibrosis by halting eosinophil infiltration

Ong, S., Ligons, D. L., Barin, J. G., Wu, L., Talor, M. V., Diny, N., Fontes, J. A., Gebremariam, E., Kass, D. A., Rose, N. R. & Čiháková, D. Mar 1 2015 In : American Journal of Pathology. 185, 3, p. 847-861 15 p.

Research output: Research - peer-reviewArticle

Myocarditis
Eosinophils
Natural Killer Cells
Fibrosis
Inflammation

The varying faces of IL-6: From cardiac protection to cardiac failure

Fontes, J. A., Rose, N. R. & Čiháková, D. Jul 1 2015 In : Cytokine. 74, 1, p. 62-68 7 p.

Research output: Research - peer-reviewArticle

Interleukin-6
Heart Failure
Tissue
Acute-Phase Reaction
Wound Healing

Transcriptomic profiles of aging in purified human immune cells

Reynolds, L. M. , Ding, J. , Taylor, J. R. , Lohman, K. , Soranzo, N. , de la Fuente, A. , Liu, T. F. , Johnson, C. , Barr, R. G. , Register, T. C. , Donohue, K. M. , Talor, M. V. , Cihakova, D. , Gu, C. , Divers, J. , Siscovick, D. , Burke, G. , Post, W. , Shea, S. , Jacobs, D. R. & 6 others Hoeschele, I., McCall, C. E., Kritchevsky, S. B., Herrington, D., Tracy, R. P. & Liu, Y. Apr 22 2015 In : BMC Genomics. 16, 1, 333

Research output: Research - peer-reviewArticle

Genes
Monocytes
Protein Biosynthesis
Gene Expression
Oxidative Phosphorylation
2014

Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy

Wu, L., Ong, S. F., Talor, M. V., Barin, J. G., Baldeviano, G. C., Kass, D. A., Bedja, D., Zhang, H., Sheikh, A., Margolick, J. B., Iwakura, Y., Rose, N. R. & Čiháková, D. 2014 In : Journal of Experimental Medicine. 211, 7, p. 1449-1464 16 p.

Research output: Research - peer-reviewArticle

Interleukin-17
Dilated Cardiomyopathy
Fibroblasts
Granulocyte-Macrophage Colony-Stimulating Factor
Myeloid Cells
2013

Control of inflammatory heart disease by CD4+ T cells

Barin, J. G. & Čiháková, D. May 2013 In : Annals of the New York Academy of Sciences. 1285, 1, p. 80-96 17 p.

Research output: Research - peer-reviewArticle

Myocarditis
Heart Diseases
T-Lymphocytes
Cells
T-cells

Fatal eosinophilic myocarditis develops in the absence of IFN-γand IL-17A

Barin, J. G., Baldeviano, G. C., Talor, M. V., Wu, L., Ong, S. F., De Fairweather, L., Bedja, D., Stickel, N. R., Fontes, J. A., Cardamone, A. B., Zheng, D., Gabrielson, K. L., Rose, N. R. & Čiháková, D. Oct 15 2013 In : Journal of Immunology. 191, 8, p. 4038-4047 10 p.

Research output: Research - peer-reviewArticle

Interleukin-17
Myocarditis
Eosinophils
Heart Diseases
Cardiac Myosins

Increased Systemic Th17 Cytokines Are Associated with Diastolic Dysfunction in Children and Adolescents with Diabetic Ketoacidosis

Hoffman, W. H., Passmore, G. G., Hannon, D. W., Talor, M. V., Fox, P., Brailer, C., Haislip, D., Keel, C., Harris, G., Rose, N. R., Fiordalisi, I. & Čiháková, D. Aug 27 2013 In : PLoS One. 8, 8, e71905

Research output: Research - peer-reviewArticle

Diabetic Ketoacidosis
Cytokines
ketosis
cytokines
Chemokines
2012

IL-33 independently induces eosinophilic pericarditis and cardiac dilation ST2 improves cardiac function

Abston, E. D., Barin, J. G., Cihakova, D., Bucek, A., Coronado, M. J., Brandt, J. E., Kim, D. B. B., Georgakopoulos, D., Gabrielson, K. L., Mitzner, W. & Fairweather, D. May 2012 In : Circulation: Heart Failure. 5, 3, p. 366-375 10 p.

Research output: Research - peer-reviewArticle

Pericarditis
Dilatation
Interleukin-33
Eosinophilia
Myocarditis

Macrophage diversity in cardiac inflammation: A review

Barin, J. G., Rose, N. R. & Čiháková, D. May 2012 In : Immunobiology. 217, 5, p. 468-475 8 p.

Research output: Research - peer-reviewArticle

Myocarditis
Phagocytes
Immunity
Heart Diseases
Animal Models

Macrophages participate in IL-17-mediated inflammation

Barin, J. G., Baldeviano, G. C., Talor, M. V., Wu, L., Ong, S., Quader, F., Chen, P., Zheng, D., Caturegli, P., Rose, N. R. & Čiháková, D. Mar 2012 In : European Journal of Immunology. 42, 3, p. 726-736 11 p.

Research output: Research - peer-reviewArticle

Interleukin-17
Macrophages
Inflammation
Interleukin-17 Receptors
Th17 Cells

Susceptibility to autoimmune myocarditis is associated with intrinsic differences in CD4 + T cells

Chen, P., Baldeviano, G. C., Ligons, D. L., Talor, M. V., Barin, J. G., Rose, N. R. & Cihakova, D. Aug 2012 In : Clinical and Experimental Immunology. 169, 2, p. 79-88 10 p.

Research output: Research - peer-reviewArticle

Myocarditis
T-Lymphocytes
Immunization
Spleen
Forkhead Transcription Factors
2010

Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy

Baldeviano, G. C., Barin, J. G., Talor, M. V., Srinivasan, S., Bedja, D., Zheng, D., Gabrielson, K., Iwakura, Y., Rose, N. R. & Cihakova, D. May 28 2010 In : Circulation Research. 106, 10, p. 1646-1655 10 p.

Research output: Research - peer-reviewArticle

Interleukin-17
Myocarditis
Dilated Cardiomyopathy
Th17 Cells
Fibrosis

Mechanisms of IFNγ regulation of autoimmune myocarditis

Barin, J. G., Talor, M. V., Baldeviano, G. C., Kimura, M., Rose, N. R. & Čiháková, D. Oct 2010 In : Experimental and Molecular Pathology. 89, 2, p. 83-91 9 p.

Research output: Research - peer-reviewArticle

Myocarditis
T-cells
Defects
T-Lymphocytes
Chemical activation
2009

Alternatively activated macrophages in infection and autoimmunity

Fairweather, D. & Cihakova, D. Nov 2009 In : Journal of Autoimmunity. 33, 3-4, p. 222-230 9 p.

Research output: Research - peer-reviewArticle

Antigen-Antibody Complex
Autoimmunity
Autoimmune Diseases
Fibrosis
Macrophages

Sex differences in a murine model of Sjögren's syndrome

Iháková, D., Talor, M. V., Barin, J. G., Baldeviano, G. C., Fairweather, D., Rose, N. R. & Burek, C. L. Sep 2009 Annals of the New York Academy of Sciences. Vol. 1173, p. 378-383 6 p. (Annals of the New York Academy of Sciences; vol. 1173)

Research output: ResearchConference contribution

Sjogren's Syndrome
Sex Characteristics
T-cells
Cells
B-Lymphocytes

Sjögren syndrome: Advances in the pathogenesis from animal models

Chiorini, J. A., Cihakova, D., Ouellette, C. E. & Caturegli, P. Nov 2009 In : Journal of Autoimmunity. 33, 3-4, p. 190-196 7 p.

Research output: Research - peer-reviewArticle

Sjogren's Syndrome
Animal Models
Salivary Glands
Autoimmune Diseases
Xerostomia
2008

Chapter 4 Pathogenesis of Myocarditis and Dilated Cardiomyopathy

Cihakova, D. & Rose, N. R. 2008 In : Advances in Immunology. 99, p. 95-114 20 p.

Research output: Research - peer-reviewArticle

Myocarditis
Dilated Cardiomyopathy
Inflammation
Interleukin-17
Giant Cells

Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation

Cihakova, D., Barin, J. G., Afanasyeva, M., Kimura, M., Fairweather, D., Berg, M., Talor, M. V., Baldeviano, G. C., Frisancho, S., Gabrielson, K., Bedja, D. & Rose, N. R. May 2008 In : American Journal of Pathology. 172, 5, p. 1195-1208 14 p.

Research output: Research - peer-reviewArticle

Interleukin-13
Myocarditis
Macrophages
Knockout Mice
T-Lymphocytes

L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart

Cihakova, D., Barin, J. G., Baldeviano, G. C., Kimura, M., Talor, M. V., Zimmerman, D. H., Talor, E. & Rose, N. R. May 2008 In : International Immunopharmacology. 8, 5, p. 624-633 10 p.

Research output: Research - peer-reviewArticle

Myocarditis
Therapeutics
Spleen
Peptides
Cardiac Myosins
2007

Cutting edge: Cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease

Frisancho-Kiss, S., Davis, S. E., Nyland, J. F., Frisancho, J. A., Cihakova, D., Barrett, M. A., Rose, N. R. & Fairweather, D. Jun 1 2007 In : Journal of Immunology. 178, 11, p. 6710-6714 5 p.

Research output: Research - peer-reviewArticle

Mucin-3
Sex Characteristics
Heart Diseases
T-Lymphocytes
Inflammation
2006

Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity

Frisancho-Kiss, S., Nyland, J. F., Davis, S. E., Barrett, M. A., Gatewood, S. J. L., Njoku, D. B., Cihakova, D., Silbergeld, E. K., Rose, N. R. & Fairweather, D. Jun 1 2006 In : Journal of Immunology. 176, 11, p. 6411-6415 5 p.

Research output: Research - peer-reviewArticle

Mucin-3
Innate Immunity
Heart Diseases
T-Lymphocytes
Regulatory T-Lymphocytes

Mechanisms underlying Myocarditis

Rose, N. R., Čiháková, D. & Barin, J. G. 2006 In : Drug Discovery Today: Disease Mechanisms. 3, 2, p. 207-212 6 p.

Research output: Research - peer-reviewArticle

Myocarditis
Cytokines
Cardiac Myosins
Interleukin-13
Enterovirus
2005

Lidský genom, monogenní diabetes mellitus a naši dětští pacienti

Lebl, J., Průhová, Š., Čiháková, D., Feigerlová, E., Pintěrová, D. & Kološtová, K. 2005 In : Cesko-Slovenska Pediatrie. 60, 6, p. 324-331 8 p.

Research output: Research - peer-reviewArticle

Human Genome
Diabetes Mellitus
Pediatrics
Wolfram Syndrome
Inborn Genetic Diseases
2004

Animal models for autoimmune myocarditis and autoimmune thyroiditis.

Ciháková, D., Sharma, R. B., Fairweather, D., Afanasyeva, M. & Rose, N. R. 2004 In : Methods in molecular medicine. 102, p. 175-193 19 p.

Research output: Research - peer-reviewArticle

Autoimmune Thyroiditis
Myocarditis
Animal Models
Cardiac Myosins
Enterovirus

Cardiomyopathies

Rose, N. R. & Cihakova, D. Jun 2004 In : Autoimmunity. 37, 4, p. 347-350 4 p.

Research output: Research - peer-reviewArticle

2002
Autoimmune Polyendocrinopathies
Eastern Europe
Addison Disease
Hypoparathyroidism
Immune Tolerance
Autoimmune Polyendocrinopathies
Heterozygote
Mutation
Autoantibodies
Parents
2001

Novel AIRE mutations and P450 cytochrome autoantibodies in Central and Eastern European patients with APECED

Cihakova, D., Trebusak, K., Heino, M., Fadeyev, V., Tiulpakov, A., Battelino, T., Tar, A., Halsz, Z., Blmel, P., Tawfik, S., Krohn, K., Lebl, J. & Peterson, P. 2001 In : Human Mutation. 18, 3, p. 225-232 8 p.

Research output: Research - peer-reviewArticle

Autoimmune Polyendocrinopathies
Autoantibodies
Cytochrome P-450 Enzyme System
Mutation
Type 1 Autoimmune polyendocrinopathy syndrome