Daniel Warren

Assistant Professor

19982019
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Research Output 1998 2019

2019

Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis

Kim, D. H., Beckett, J. D., Nagpal, V., Seman-Senderos, M. A., Gould, R. A., Creamer, T. J., MacFarlane, E., Chen, Y., Bedja, D., Butcher, J. T., Mitzner, W. A., Rouf, R., Hata, S., Warren, D. & Dietz, H. C., Jul 17 2019, In : Science translational medicine. 11, 501, eaau2814.

Research output: Contribution to journalArticle

Calpain
Transforming Growth Factors
Fibrosis
Myofibroblasts
Therapeutics

Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis

Shin, J. Y., Beckett, J. D., Bagirzadeh, R., Creamer, T. J., Shah, A. A., McMahan, Z., Paik, J. J., Sampedro, M. M., MacFarlane, E. G., Beer, M. A., Warren, D., Wigley, F. M. & Dietz, H. C., Jan 1 2019, In : Science translational medicine. 11, 497, eaaw0790.

Research output: Contribution to journalArticle

Systemic Scleroderma
Epigenomics
Fibrosis
Skin
Autocrine Communication
2018

Transfusion of leukoreduced blood products and risk of antibody-mediated rejection of renal allografts

Bynum, J. P., Zachary, A., Ness, P. M., Luo, X., Bagnasco, S. M., King, K. E., Segev, D., Orandi, B. J., Warren, D., Fuller, A., Ciappi, A., Montgomery, R. & Tobian, A. A., Aug 1 2018, In : Transfusion. 58, 8, p. 1951-1957 7 p.

Research output: Contribution to journalArticle

Blood Transfusion
Allografts
Kidney
Antibodies
Erythrocyte Transfusion
2017

Chronic Gastrointestinal Dysmotility and Pain Following Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis

John, G. K., Singh, V., Moran, R. A., Warren, D., Sun, Z. L., Desai, N. M., Walsh, C., Kalyani, R. R., Hall, E., Hirose, K., Makary, M. A. & Stein, E., Jan 12 2017, (Accepted/In press) In : Journal of Gastrointestinal Surgery. p. 1-6 6 p.

Research output: Contribution to journalArticle

Pancreatectomy
Autologous Transplantation
Chronic Pancreatitis
Pain
Abdominal Pain

Glycemic predictors of insulin independence after total pancreatectomy with islet autotransplantation

Quartuccio, M., Hall, E., Singh, V., Makary, M. A., Hirose, K., Desai, N. M., Walsh, C., Warren, D., Sun, Z. L., Stein, E. & Kalyani, R. R., Mar 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 3, p. 801-809 9 p.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Pancreatectomy
Autologous Transplantation
Insulin
Glucose Tolerance Test
Pancreatectomy
Autologous Transplantation
Chronic Pancreatitis
Therapeutics
Operative Time

Prevalence and predictors of pain and opioid analgesic use following total pancreatectomy with islet autotransplantation for pancreatitis

Moran, R. A., Klapheke, R., John, G. K., Devlin, S., Warren, D., Desai, N. M., Sun, Z. L., Walsh, C., Kalyani, R. R., Hall, E., Stein, E., Kalloo, A. N., Zaheer, A., Hirose, K., Makary, M. A. & Singh, V., 2017, (Accepted/In press) In : Pancreatology.

Research output: Contribution to journalArticle

Pancreatectomy
Autologous Transplantation
Pancreatitis
Abdominal Pain
Opioid Analgesics
2015
Islets of Langerhans Transplantation
Pancreatectomy
Gastric Emptying
Chronic Pancreatitis
Length of Stay

Systemic delivery of scAAV8-encoded MiR-29a ameliorates hepatic fibrosis in carbon tetrachloride-treated mice

Knabel, M. K., Ramachandran, K., Karhadkar, S., Hwang, H. W., Creamer, T. J., Chivukula, R. R., Sheikh, F., Clark, K. R., Torbenson, M., Montgomery, R. A., Cameron, A. M., Mendell, J. T. & Warren, D., Apr 29 2015, In : PLoS One. 10, 4, e0124411.

Research output: Contribution to journalArticle

Dependovirus
carbon tetrachloride
liver cirrhosis
Carbon Tetrachloride
fibrosis
2014

Successful transplantation of kidney allografts in sensitized rats after syngeneic hematopoietic stem cell transplantation and fludarabine

Fu, Y., Sun, Z. L., Fuchs, E. J., Wang, Y., Shen, Z. Y., Maeda, H., Lin, Q., Warren, D., Williams, G. M. & Montgomery, R. A., Oct 1 2014, In : American Journal of Transplantation. 14, 10, p. 2375-2383 9 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Kidney Transplantation
Allografts
Antibodies
Tissue Donors
2012

HLA incompatible renal transplantation

Montgomery, R. A., Warren, D., Segev, D. & Zachary, A. A., Aug 2012, In : Current Opinion in Organ Transplantation. 17, 4, p. 386-392 7 p.

Research output: Contribution to journalArticle

HLA Antigens
Kidney Transplantation
Tissue Donors
Complement Inactivating Agents
Kidney

In vitro and ex vivo delivery of short hairpin RNAs for control of hepatitis C viral transcript expression

Lonze, B. E., Holzer, H. T., Knabel, M. K., Locke, J. E., DiCamillo, G. A., Karhadkar, S. S., Montgomery, R. A., Sun, Z. L., Warren, D. & Cameron, A. M., Apr 2012, In : Archives of Surgery. 147, 4, p. 384-387 4 p.

Research output: Contribution to journalArticle

Hepatitis C
Hepacivirus
Small Interfering RNA
Transplants
Liver Transplantation

Outcomes of ABO-incompatible kidney transplantation in the United States

Montgomery, J. R., Berger, J. C., Warren, D., James, N. T., Montgomery, R. A. & Segev, D., Mar 27 2012, In : Transplantation. 93, 6, p. 603-609 7 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Tissue Donors
Blood Donors
Transplants
Confidence Intervals

Re: Desensitization in HLA-incompatible kidney recipients and survival

Montgomery, R. A., Lonze, B. E., King, K. E., Kraus, E., Kucirka, L. M., Locke, J. E., Warren, D., Simpkins, C. E., Dagher, N. N., Singer, A. L., Zachary, A. A. & Segev, D., May 2012, In : Journal of Urology. 187, 5, p. 1766-1767 2 p.

Research output: Contribution to journalArticle

Kidney
2011

Desensitization in HLA-incompatible kidney recipients and survival

Montgomery, R. A., Lonze, B. E., King, K. E., Kraus, E., Kucirka, L. M., Locke, J. E., Warren, D., Simpkins, C. E., Dagher, N. N., Singer, A. L., Zachary, A. A. & Segev, D., Jul 28 2011, In : New England Journal of Medicine. 365, 4, p. 318-326 9 p.

Research output: Contribution to journalArticle

Dialysis
Kidney Transplantation
Kidney
Transplantation
Survival

Humoral immunity and antibody-mediated rejection in solid organ transplantation

Montgomery, R. A., Cozzi, E., West, L. J. & Warren, D., Aug 2011, In : Seminars in Immunology. 23, 4, p. 224-234 11 p.

Research output: Contribution to journalArticle

Organ Transplantation
Humoral Immunity
Antibodies
Immune System
Heterophile Antigens

Incompatible live-donor kidney transplantation in the United States: Results of a national survey

Garonzik, J., Montgomery, R. A., Kucirka, L. M., Berger, J. C., Warren, D. & Segev, D., Aug 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 8, p. 2041-2046 6 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Tissue Donors
Transplants
Plasmapheresis
Registries

Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice

Frischmeyer-Guerrerio, P. A., Montgomery, R. A., Warren, D., Cooke, S. K., Lutz, J., Sonnenday, C. J., Guerrerio, A. L. & Dietz, H. C., Jun 28 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 26, p. 10638-10643 6 p.

Research output: Contribution to journalArticle

Thymocytes
T-Cell Antigen Receptor
Nonsense Mediated mRNA Decay
Nonsense Codon
Transgenes
2010

Incompatible kidney transplantation: Lessons from a decade of desensitization and paired kidney exchange

Warren, D. & Montgomery, R. A., Jul 2010, In : Immunologic Research. 47, 1-3, p. 257-264 8 p.

Research output: Contribution to journalArticle

Kidney Transplantation
HLA Antigens
Kidney
Waiting Lists
Living Donors

Stem cell mobilization is life saving in an animal model of acute liver failure

Mark, A. L., Sun, Z. L., Warren, D., Lonze, B. E., Knabel, M. K., Williams, G. M. M., Locke, J. E., Montgomery, R. A. & Cameron, A. M., Oct 2010, In : Annals of Surgery. 252, 4, p. 591-595 5 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Mobilization
Acute Liver Failure
Animal Models
Granulocyte Colony-Stimulating Factor
Liver
2009

ABO incompatible renal transplantation: A paradigm ready for broad implementation

Montgomery, R. A., Locke, J. E., King, K. E., Segev, D., Warren, D., Kraus, E., Cooper, M., Simpkins, C. E., Singer, A. L., Stewart, Z. A., Melancon, J. K., Ratner, L., Zachary, A. A. & Haas, M., Apr 27 2009, In : Transplantation. 87, 8, p. 1246-1255 10 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Antibodies
Transplants
Immunosuppression
B-Lymphocytes

C4d deposition without rejection correlates with reduced early scarring in ABO-incompatible renal allografts

Haas, M., Segev, D., Racusen, L. C., Bagnasco, S. M., Locke, J. E., Warren, D., Simpkins, C. E., Lepley, D., King, K. E., Kraus, E. & Montgomery, R. A., Jan 2009, In : Journal of the American Society of Nephrology. 20, 1, p. 197-204 8 p.

Research output: Contribution to journalArticle

Cicatrix
Allografts
Kidney
Antibodies
Transplantation

Histidine-tryptophan-ketoglutarate (HTK) is associated with reduced graft survival of deceased donor kidney transplants

Stewart, Z. A., Lonze, B. E., Warren, D., Dagher, N. N., Singer, A. L., Montgomery, R. A. & Segev, D., May 2009, In : American Journal of Transplantation. 9, 5, p. 1048-1054 7 p.

Research output: Contribution to journalArticle

Graft Survival
Histidine
Tryptophan
Tissue Donors
Transplants

Kidney transplantation in previous heart or lung recipients

Lonze, B. E., Warren, D., Stewart, Z. A., Dagher, N. N., Singer, A. L., Shah, A. S., Montgomery, R. A. & Segev, D., Mar 2009, In : American Journal of Transplantation. 9, 3, p. 578-585 8 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Kidney
Lung
Transplants
Graft Survival

Proinflammatory events are associated with significant increases in breadth and strength of HLA-specific antibody

Locke, J. E., Zachary, A. A., Warren, D., Segev, D., Houp, J. A., Montgomery, R. A. & Leffell, M. S., Sep 2009, In : American Journal of Transplantation. 9, 9, p. 2136-2139 4 p.

Research output: Contribution to journalArticle

Antibodies
Transplants
Infection
Registries
Transplantation

Rapid accomodation of an a1 renal allograft after preconditioning for ABO-incompatible transplantation

Allen, G., Simpkins, C. E., Segev, D., Warren, D., King, K. E., Taube, J. M., Locke, J., Baldwin, W., Haas, M., Chivukula, R. & Montgomery, R. A., 2009, Contributions to Nephrology. Vol. 162. p. 35-46 12 p. (Contributions to Nephrology; vol. 162).

Research output: Chapter in Book/Report/Conference proceedingChapter

Allografts
Transplantation
Kidney
Antibodies
Blood Group Antigens

Renal transplant in HIV-positive patients: Long-term outcomes and risk factors for graft loss

Locke, J. E., Montgomery, R. A., Warren, D., Subramanian, A. & Segev, D., Jan 2009, In : Archives of Surgery. 144, 1, p. 83-86 4 p.

Research output: Contribution to journalArticle

HIV
Transplants
Kidney
Cold Ischemia
Donor Selection

Subclinical rejection in stable positive crossmatch kidney transplant patients: Incidence and correlations

Kraus, E., Parekh, R. S., Oberai, P., Lepley, D., Segev, D., Bagnasco, S. M., Collins, V., Leffell, M., Lucas, D., Rabb, H., Racusen, L. C., Singer, A. L., Stewart, Z. A., Warren, D., Zachary, A. A., Haas, M. & Montgomery, R. A., Aug 2009, In : American Journal of Transplantation. 9, 8, p. 1826-1834 9 p.

Research output: Contribution to journalArticle

Transplants
Kidney
Antibodies
Incidence
Biopsy

The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejection

Locke, J. E., Magro, C. M., Singer, A. L., Segev, D., Haas, M., Hillel, A. T., King, K. E., Kraus, E., Lees, L. M., Melancon, J. K., Stewart, Z. A., Warren, D., Zachary, A. A. & Montgomery, R. A., Jan 2009, In : American Journal of Transplantation. 9, 1, p. 231-235 5 p.

Research output: Contribution to journalArticle

Complement C5
Salvage Therapy
Complement System Proteins
Complement Membrane Attack Complex
Plasmapheresis
2008

Declining outcomes in simultaneous liver-kidney transplantation in the MELD era: Ineffective usage of renal allografts

Locke, J. E., Warren, D., Singer, A. L., Segev, D., Simpkins, C. E., Maley, W. R., Montgomery, R. A., Danovitch, G. & Cameron, A. M., Apr 2008, In : Transplantation. 85, 7, p. 935-942 8 p.

Research output: Contribution to journalArticle

End Stage Liver Disease
Liver Transplantation
Kidney Transplantation
Allografts
Transplants

Donor ethnicity influences outcomes following deceased-donor kidney transplantation in black recipients

Locke, J. E., Warren, D., Dominici, F., Cameron, A. M., Leffell, M. S., McRann, D. A., Melancon, J. K., Segev, D., Simpkins, C. E., Singer, A. L., Zachary, A. A. & Montgomery, R. A., Oct 2008, In : Journal of the American Society of Nephrology. 19, 10, p. 2011-2019 9 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Tissue Donors
Kidney
Brain Death
Risk Reduction Behavior

Generation of humanized animal livers using embryoid body-derived stem cell transplant

Locke, J. E., Sun, Z. L., Warren, D., Sheets, T. P., Holzer, H., Shamblott, M. J., Montgomery, R. A. & Cameron, A. M., Sep 2008, In : Annals of Surgery. 248, 3, p. 487-491 5 p.

Research output: Contribution to journalArticle

Embryoid Bodies
Stem Cells
Transplants
Liver
Animal Structures

Obesity impacts access to kidney transplantation

Segev, D., Simpkins, C. E., Thompson, R., Locke, J. E., Warren, D. & Montgomery, R. A., Feb 2008, In : Journal of the American Society of Nephrology. 19, 2, p. 349-355 7 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Obesity
Body Mass Index
Motivation
Length of Stay
2007

Cold ischemia time and allograft outcomes in live donor renal transplantation: Is live donor organ transport feasible?

Simpkins, C. E., Montgomery, R. A., Hawxby, A. M., Locke, J. E., Gentry, S. E., Warren, D. & Segev, D., Jan 2007, In : American Journal of Transplantation. 7, 1, p. 99-107 9 p.

Research output: Contribution to journalArticle

Cold Ischemia
Kidney Transplantation
Allografts
Tissue Donors
Delayed Graft Function

Outcomes of kidneys from donors after cardiac death: Implications for allocation and preservation

Locke, J. E., Segev, D., Warren, D., Dominici, F., Simpkins, C. E. & Montgomery, R. A., Jul 2007, In : American Journal of Transplantation. 7, 7, p. 1797-1807 11 p.

Research output: Contribution to journalArticle

Tissue Donors
Kidney
Delayed Graft Function
Transplants
Incidence

Subclinical acute antibody-mediated rejection in positive crossmatch renal allografts

Haas, M., Montgomery, R. A., Segev, D., Rahman, M. H., Racusen, L. C., Bagnasco, S. M., Simpkins, C. E., Warren, D., Lepley, D., Zachary, A. A. & Kraus, E., Mar 2007, In : American Journal of Transplantation. 7, 3, p. 576-585 10 p.

Research output: Contribution to journalArticle

Allografts
Kidney
Antibodies
Creatinine
Biopsy

The utility of splenectomy as rescue treatment for severe acute antibody mediated rejection

Locke, J. E., Zachary, A. A., Haas, M., Melancon, J. K., Warren, D., Simpkins, C. E., Segev, D. & Montgomery, R. A., Apr 2007, In : American Journal of Transplantation. 7, 4, p. 842-846 5 p.

Research output: Contribution to journalArticle

Plasmapheresis
Splenectomy
Kidney
Antibodies
Allografts
2006

C4d and C3d staining in biopsies of ABO- and HLA-Incompatible renal allografts: Correlation with histologic findings

Haas, M., Rahman, M. H., Racusen, L. C., Kraus, E., Bagnasco, S. M., Segev, D., Simpkins, C. E., Warren, D., King, K. E., Zachary, A. A. & Montgomery, R. A., Aug 2006, In : American Journal of Transplantation. 6, 8, p. 1829-1840 12 p.

Research output: Contribution to journalArticle

Allografts
Staining and Labeling
Transplants
Kidney
Biopsy

Domino paired kidney donation: a strategy to make best use of live non-directed donation

Montgomery, R. A., Gentry, S. E., Marks, W. H., Warren, D., Hiller, J., Houp, J., Zachary, A. A., Melancon, J. K., Maley, W. R., Rabb, H., Simpkins, C. & Segev, D., Jul 29 2006, In : The Lancet. 368, 9533, p. 419-421 3 p.

Research output: Contribution to journalArticle

Blood Group Incompatibility
Tissue and Organ Procurement
Waiting Lists
Resource Allocation
Living Donors

Rescue splenectomy for severe acute antibody-mediated rejection.

Locke, J. E., Zachary, A. A., Mohammed, B. S., Warren, D. & Montgomery, R. A., 2006, In : Clinical transplants. p. 518-520 3 p.

Research output: Contribution to journalArticle

Isoantibodies
Graft Rejection
Diabetic Nephropathies
Splenectomy
Immunosuppressive Agents
2005

ABO incompatible high-titer renal transplantation without splenectomy or anti-CD20 treatment

Segev, D., Simpkins, C. E., Warren, D., King, K. E., Shirey, R. S., Maley, W. R., Melancon, J. K., Cooper, M., Kozlowski, T. & Montgomery, R. A., Oct 2005, In : American Journal of Transplantation. 5, 10, p. 2570-2575 6 p.

Research output: Contribution to journalArticle

Splenectomy
Kidney Transplantation
Plasmapheresis
Transplantation
Immunoglobulins

Clinical results from transplanting incompatible live kidney donor/recipient pairs using kidney paired donation

Montgomery, R. A., Zachary, A. A., Ratner, L. E., Segev, D., Hiller, J. M., Houp, J., Cooper, M., Kavoussi, L., Jarrett, T., Burdick, J. F., Maley, W. R., Melancon, J. K., Kozlowski, T., Simpkins, C. E., Phillips, M., Desai, A., Collins, V., Reeb, B., Kraus, E., Rabb, H. & 2 others, Leffell, M. S. & Warren, D., Oct 5 2005, In : Journal of the American Medical Association. 294, 13, p. 1655-1663 9 p.

Research output: Contribution to journalArticle

Tissue Donors
Kidney
Transplants
Graft Survival
Survival Rate

Erratum: Multiple-laboratory comparison of microarray platforms (Nature Methods (2005) vol.2 (345-349))

Irizarry, R. A., Warren, D., Spencer, F., Kim, I. F., Biswal, S., Frank, B. C., Gabrielson, E., Garcia, J. G. N., Geoghegan, J., Germino, G., Griffin, C., Hilmer, S. C., Hoffman, E., Jedlicka, A. E., Kawasaki, E., Martínez-Murillo, F., Morsberger, L., Lee, H., Petersen, D., Quackenbush, J. & 5 others, Scott, A. L., Wilson, M., Yang, Y., Ye, S. Q. & Yu, W., Jun 2005, In : Nature Methods. 2, 6, p. 477 1 p.

Research output: Contribution to journalArticle

Microarrays

Kidney paired donation and optimizing the use of live donor organs

Segev, D. L., Gentry, S. E., Warren, D. S., Reeb, B. & Montgomery, R. A., Apr 20 2005, In : Journal of the American Medical Association. 293, 15, p. 1883-1890 8 p.

Research output: Contribution to journalArticle

Tissue Donors
Transplants
Kidney
Kidney Transplantation
Chronic Kidney Failure

Modulating alloimmune responses with plasmapheresis and IVIG

Warren, D., Simpkins, C. E., Cooper, M. & Montgomery, R. A., Jun 2005, In : Current Drug Targets - Cardiovascular and Haematological Disorders. 5, 3, p. 215-222 8 p.

Research output: Contribution to journalArticle

Plasmapheresis
Intravenous Immunoglobulins
Kidney Transplantation
Blood Group Antigens
Antibodies

Multiple-laboratory comparison of microarray platforms

Irizarry, R. A., Warren, D., Spencer, F., Kim, I. F., Biswal, S., Frank, B. C., Gabrielson, E., Garcia, J. G. N., Geoghegan, J., Germino, G., Griffin, C., Hilmer, S. C., Hoffman, E., Jedlicka, A. E., Kawasaki, E., Martínez-Murillo, F., Morsberger, L., Lee, H., Petersen, D., Quackenbush, J. & 5 others, Scott, A. L., Wilson, M., Yang, Y., Ye, S. Q. & Yu, W., May 2005, In : Nature Methods. 2, 5, p. 345-349 5 p.

Research output: Contribution to journalArticle

RNA
Baltimore
Meta-Analysis
Research Personnel
Technology

The use of anti-CD20 in ABO-incompatible renal transplantation [2]

Sonnenday, C., Warren, D. & Montgomery, R., Dec 2005, In : American Journal of Transplantation. 5, 12, p. 3020 1 p.

Research output: Contribution to journalArticle

Kidney Transplantation
2004

A novel chimeric ribozyme vector produces potent inhibition of ICAM-1 expression on ischemic vascular endothelium

Sonnenday, C. J., Warren, D., Cooke, S. K., Dietz, H. C. & Montgomery, R. A., Dec 2004, In : Journal of Gene Medicine. 6, 12, p. 1394-1402 9 p.

Research output: Contribution to journalArticle

Catalytic RNA
Vascular Endothelium
Intercellular Adhesion Molecule-1
Reperfusion Injury
Endothelial Cells

Antibody, complement and accommodation in ABO-incompatible transplants

King, K. E., Warren, D., Samaniego-Picota, M., Campbell-Lee, S., Montgomery, R. A. & Baldwin, W. M., Oct 2004, In : Current Opinion in Immunology. 16, 5, p. 545-549 5 p.

Research output: Contribution to journalArticle

Allografts
Endothelial Cells
Complement C3b
Transplants
Kidney

Plasmapheresis, CMV hyperimmune globulin, and anti-CD20 allow ABO-incompatible renal transplantation without splenectomy

Sonnenday, C. J., Warren, D., Cooper, M., Samaniego, M., Haas, M., King, K. E., Shirey, R. S., Simpkins, C. E. & Montgomery, R. A., Aug 2004, In : American Journal of Transplantation. 4, 8, p. 1315-1322 8 p.

Research output: Contribution to journalArticle

Plasmapheresis
Globulins
Splenectomy
Kidney Transplantation
Antibodies