D Wade Gibson

Professor Emeritus

1971 …2014

Research output per year

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Research Output

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Article
2014

Nelfinavir inhibits maturation and export of herpes simplex virus 1

Kalu, N. N., Desai, P. J., Shirley, C. M., Gibson, W., Dennis, P. A. & Ambinder, R. F., 2014, In : Journal of virology. 88, 10, p. 5455-5461 7 p.

Research output: Contribution to journalArticle

Recovery of an HMWP/hmwBP (pUL48/pUL47) complex from virions of human cytomegalovirus: Subunit interactions, oligomer composition, and deubiquitylase activity

Tullman, J. A., Harmon, M. E., Delannoy, M. & Gibson, W., 2014, In : Journal of virology. 88, 15, p. 8256-8267 12 p.

Research output: Contribution to journalArticle

2011

Cytomegalovirus capsid protease: Biological substrates are cleaved more efficiently by full-length enzyme (pUL80a) than by the catalytic domain (assemblin)

Fernandes, S. M., Brignole, E. J. & Gibson, W., Apr 1 2011, In : Journal of virology. 85, 7, p. 3526-3534 9 p.

Research output: Contribution to journalArticle

2009

Cleavage specificity of the UL48 deubiquitinating protease activity of human cytomegalovirus and the growth of an active-site mutant virus in cultured cells

Kim, E. T., Oh, S. E., Lee, Y. O., Gibson, W. & Ahn, J. H., Dec 1 2009, In : Journal of virology. 83, 23, p. 12046-12056 11 p.

Research output: Contribution to journalArticle

2008
2007

The amino-conserved domain of human cytomegalovirus UL80a proteins is required for key interactions during early stages of capsid formation and virus production

Loveland, A. N., Nguyen, N. L., Brignole, E. J. & Gibson, W., Jan 1 2007, In : Journal of virology. 81, 2, p. 620-628 9 p.

Research output: Contribution to journalArticle

2006

High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: Mutant viruses altered in its active-site cysteine or histidine are viable

Wang, J., Loveland, A. N., Kattenhorn, L. M., Ploegh, H. L. & Gibson, W., Jun 1 2006, In : Journal of virology. 80, 12, p. 6003-6012 10 p.

Research output: Contribution to journalArticle

2005

Chemical rescue of I-site cleavage in living cells and in vitro discriminates between the cytomegalovirus protease, assemblin, and its precursor, pUL80a

McCartney, S. A., Brignole, E. J., Kolegraff, K. N., Loveland, A. N., Ussin, L. S. M. & Gibson, W., Sep 30 2005, In : Journal of Biological Chemistry. 280, 39, p. 33206-33212 7 p.

Research output: Contribution to journalArticle

Cleavage of human cytomegalovirus protease pUL80a at internal and cryptic sites is not essential but enhances infectivity

Loveland, A. N., Chan, C. K., Brignole, E. J. & Gibson, W., Oct 1 2005, In : Journal of virology. 79, 20, p. 12961-12968 8 p.

Research output: Contribution to journalArticle

2004
2003

Microtubule network facilitates nuclear targeting of human cytomegalovirus capsid

Ogawa-Goto, K., Tanaka, K., Gibson, W., Moriishi, E., Miura, Y., Kurata, T., Irie, S. & Sata, T., Aug 1 2003, In : Journal of virology. 77, 15, p. 8541-8547 7 p.

Research output: Contribution to journalArticle

2002

Cytomegalovirus assemblin (pUL80a): Cleavage at internal site not essential for virus growth; proteinase absent from virions

Chan, C. K., Brignole, E. J. & Gibson, W., Aug 20 2002, In : Journal of virology. 76, 17, p. 8667-8674 8 p.

Research output: Contribution to journalArticle

2001

Cytomegalovirus basic phosphoprotein (pUL32) binds to capsids in vitro through its amino one-third

Baxter, M. K. & Gibson, W., Jul 24 2001, In : Journal of virology. 75, 15, p. 6865-6873 9 p.

Research output: Contribution to journalArticle

1999

Capsid structure of simian cytomegalovirus from cryoelectron microscopy: Evidence for tegument attachment sites

Trus, B. L., Gibson, W., Cheng, N. & Steven, A. C., Mar 4 1999, In : Journal of virology. 73, 3, p. 2181-2192 12 p.

Research output: Contribution to journalArticle

1998
1997

Assemblin, an essential herpesvirus proteinase

Gibson, W. & Hall, M. R. T., Aug 11 1997, In : Drug Design and Discovery. 15, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Assemblin homolog of herpes simplex virus type 1 retains proteolytic activity when expressed as a recombinant two-chain enzyme

Hall, M. R. T. & Gibson, W., Jan 6 1997, In : Virology. 227, 1, p. 160-167 8 p.

Research output: Contribution to journalArticle

Human cytomegalovirus capsid assembly protein precursor (pUL80.5) Interacts with itself and with the major capsid protein (pUL86) through two different domains

Wood, L. J., Baxter, M. K., Plafker, S. M. & Gibson, W., Jan 1 1997, In : Journal of virology. 71, 1, p. 179-190 12 p.

Research output: Contribution to journalArticle

1996

Cytomegalovirus 'missing' capsid protein identified as heat-aggregable product of human cytomegalovirus UL46

Gibson, W., Baxter, M. K. & Clopper, K. S., Nov 1 1996, In : Journal of virology. 70, 11, p. 7454-7461 8 p.

Research output: Contribution to journalArticle

Human cytomegalovirus (HCMV) smallest capsid protein identified as product of short open reading frame located between HCMV UL48 and UL49

Gibson, W., Clopper, K. S., Britt, W. J. & Baxter, M. K., Aug 1 1996, In : Journal of virology. 70, 8, p. 5680-5683 4 p.

Research output: Contribution to journalArticle

Identification of the human cytomegalovirus G protein-coupled receptor homologue encoded by UL33 in infected cells and enveloped virus particles

Margulies, B. J., Browne, H. & Gibson, W., Nov 1 1996, In : Virology. 225, 1, p. 111-125 15 p.

Research output: Contribution to journalArticle

Structure and assembly of the virion

Gibson, W., Jan 1 1996, In : Intervirology. 39, 5-6, p. 389-400 12 p.

Research output: Contribution to journalArticle

Virus-specific interaction between the human cytomegalovirus major capsid protein and the C terminus of the assembly protein precursor

Beaudet-Miller, M., Zhang, R., Durkin, J., Gibson, W., Kwong, A. D. & Hong, Z., Nov 1 1996, In : Journal of virology. 70, 11, p. 8081-8088 8 p.

Research output: Contribution to journalArticle

1995

Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals

Gibson, W., Welch, A. R. & Hall, M. R. T., Jul 1 1995, In : Perspectives in Drug Discovery and Design. 2, 3, p. 413-426 14 p.

Research output: Contribution to journalArticle

Cytomegalovirus protein substrates are not cleaved by the herpes simplex virus type 1 proteinase

Welch, A. R., Villarreal, E. C. & Gibson, W., Jan 1 1995, In : Journal of virology. 69, 1, p. 341-347 7 p.

Research output: Contribution to journalArticle

Human cytomegalovirus proteinase: Candidate glutamic acid identified as third member of putative active-site triad

Cox, G. A., Wakulchik, M., Sassmannshausen, L. M., Gibson, W. & Villarreal, E. C., Jan 1 1995, In : Journal of virology. 69, 7, p. 4524-4528 5 p.

Research output: Contribution to journalArticle

1994

Human cytomegalovirus maturational proteinase: Expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites

Burck, P. J., Berg, D. H., Luk, T. P., Sassmannshausen, L. M., Wakulchik, M., Smith, D. P., Hsiung, H. M., Becker, G. W., Gibson, W. & Villarreal, E. C., May 1 1994, In : Journal of virology. 68, 5, p. 2937-2946 10 p.

Research output: Contribution to journalArticle

Site-specific glycosylation of the human cytomegalovirus tegument basic phosphoprotein (UL32) at serine 921 and serine 952

Greis, K. D., Gibson, W. & Hart, G. W., Dec 1 1994, In : Journal of virology. 68, 12, p. 8339-8349 11 p.

Research output: Contribution to journalArticle

Transient transfection assay of the herpesvirus maturational proteinase, assemblin

Gibson, W., Rwelch, A. & Ludford, J. M., Jan 1 1994, In : Methods in enzymology. 244, C, p. 399-411 13 p.

Research output: Contribution to journalArticle

1993
1991
Open Access

Cytomegalovirus assembly protein nested gene family: Four 3'-coterminal transcripts encode four in-frame, overlapping proteins

Welch, A. R., McNally, L. M. & Gibson, W., Jan 1 1991, In : Journal of virology. 65, 8, p. 4091-4100 10 p.

Research output: Contribution to journalArticle

The 45-kilodalton protein of cytomegalovirus (Colburn) B-capsids is an amino-terminal extension form of the assembly protein

Schenk, P., Woods, A. S. & Gibson, W., Jan 1 1991, In : Journal of virology. 65, 3, p. 1525-1529 5 p.

Research output: Contribution to journalArticle

1990

Evidence that HIV-1 gag precursor shares antigenic sites with the major capsid protein of human cytomegalovirus

Gibson, W., McNally, L. M., Benveniste, R. E. & Ward, J. M., Apr 1990, In : Virology. 175, 2, p. 595-599 5 p.

Research output: Contribution to journalArticle

Identification of precursor to cytomegalovirus capsid assembly protein and evidence that processing results in loss of its carboxy-terminal end

Gibson, W., Marcy, A. I., Comolli, J. C. & Lee, J., Jan 1 1990, In : Journal of virology. 64, 3, p. 1241-1249 9 p.

Research output: Contribution to journalArticle

Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination

Hamzeh, F. M., Lietman, P. S., Gibson, W. & Hayward, G. S., Jan 1 1990, In : Journal of virology. 64, 12, p. 6184-6195 12 p.

Research output: Contribution to journalArticle

Sequence requirements for proteolytic processing of glycoprotein B of human cytomegalovirus strain Towne

Spaete, R. R., Saxena, A., Scott, P. I., Song, G. J., Probert, W. S., Britt, W. J., Gibson, W., Rasmussen, L. & Pachl, C., Jan 1 1990, In : Journal of virology. 64, 6, p. 2922-2931 10 p.

Research output: Contribution to journalArticle

1989

Primate cytomegalovirus assembly protein: Genome location and nucleotide sequence

Robson, L. & Gibson, W., Jan 1 1989, In : Journal of virology. 63, 2, p. 669-674 6 p.

Research output: Contribution to journalArticle

1988

Primate cytomegalovirus assembly: Evidence that DNA packaging occurs subsequent to B capsid assembly

Lee, J. Y., Irmiere, A. & Gibson, W., Nov 1988, In : Virology. 167, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

Virion basic phosphoprotein from human cytomegalovirus contains O-linked N-acetylglucosamine.

Benko, D. M., Haltiwanger, R. S., Hart, G. W. & Gibson, W., Apr 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2573-2577 5 p.

Research output: Contribution to journalArticle

Open Access
1987

Immunological characterization of an early cytomegalovirus single-strand DNA-binding protein with similarities to the HSV major DNA-binding protein

Anders, D. G., Kidd, J. R. & Gibson, W., Dec 1987, In : Virology. 161, 2, p. 579-588 10 p.

Research output: Contribution to journalArticle

1986

Identification and characterization of a major early cytomegalovirus DNA-binding protein

Anders, D. G., Irmiere, A. & Gibson, W., Jan 1 1986, In : Journal of virology. 58, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

Primate cytomegalovirus glycoproteins: Lectin-binding properties and sensitivities to glycosidases

Benko, D. M. & Gibson, W., Jan 1 1986, In : Journal of virology. 59, 3, p. 703-713 11 p.

Research output: Contribution to journalArticle