Cyrus David Mintz

Assistant Professor

19992019
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General Anesthetics Medicine & Life Sciences

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Research Output 1999 2019

Early Developmental Exposure to Repetitive Long Duration of Midazolam Sedation Causes Behavioral and Synaptic Alterations in a Rodent Model of Neurodevelopment

Xu, J., Mathena, R. P., Singh, S., Kim, J., Long, J. J., Li, Q., Junn, S., Blaize, E. & Mintz, C. D., Jan 1 2019, In : Journal of Neurosurgical Anesthesiology. 31, 1, p. 151-162 12 p.

Research output: Contribution to journalArticle

Midazolam
Synapses
Rodentia
Anesthesia
Learning

Anesthetics disrupt brain development via actions on the mTOR pathway

Xu, J., Kang, E. & Mintz, C. D., Mar 28 2018, (Accepted/In press) In : Communicative and Integrative Biology.

Research output: Contribution to journalArticle

Sirolimus
anesthetics
Anesthetics
anesthesia
brain

Early developmental exposure to general anesthetic agents in primary neuron culture disrupts synapse formation via actions on the mTOR pathway

Xu, J., Mathena, R. P., Xu, M., Wang, Y., Chang, C., Fang, Y., Zhang, P. & Mintz, C. D., Aug 1 2018, In : International Journal of Molecular Sciences. 19, 8, 2183.

Research output: Contribution to journalArticle

anesthetics
synapses
Anesthetics
General Anesthetics
Sirolimus

Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway

Kang, E., Jiang, D., Ryu, Y. K., Lim, S., Kwak, M., Gray, C., Xu, M., Choi, J. H., Junn, S., Kim, J., Xu, J., Schaefer, M., Johns, R. A., Song, H., Ming, G. L. & Mintz, C. D., Jul 6 2017, In : PLoS Biology. 15, 7, e2001246.

Research output: Contribution to journalArticle

Isoflurane
isoflurane
Neurons
neonates
neurons

Evidence of an association between brain cellular injury and cognitive decline after non-cardiac surgery

Rappold, T., Laflam, A., Hori, D., Brown, C., Brandt, J., Mintz, C. D., Sieber, F., Gottschalk, A., Yenokyan, G., Everett, A. D., Hogue, C. W. & Absalom, A. R., Jan 1 2016, In : British Journal of Anaesthesia. 116, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Brain Injuries
Glial Fibrillary Acidic Protein
Phosphopyruvate Hydratase
Cognition
Blood Proteins