Cynthia Zahnow

Associate Professor

1990 …2018
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Epigenomics Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
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Histidine Decarboxylase Medicine & Life Sciences
Azacitidine Medicine & Life Sciences
Breast Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences

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Research Output 1990 2018

Triple Negative Breast Neoplasms
Drug Therapy
gemcitabine
Breast Neoplasms
Carboplatin

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y. W., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Chiu Yen, R. W., Zahnow, C. A., Ahuja, N., Baylin, S. B. & Easwaran, H., Feb 12 2018, In : Cancer Cell. 33, 2, p. 309-321.e5

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Developmental Genes
Neoplasms
Epigenomics

DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer

Luo, N., Nixon, M. J., Gonzalez-Ericsson, P. I., Sanchez, V., Opalenik, S. R., Li, H., Zahnow, C. A., Nickels, M. L., Liu, F., Tantawy, M. N., Sanders, M. E., Manning, H. C. & Balko, J. M., Dec 1 2018, In : Nature Communications. 9, 1, 248

Research output: Contribution to journalArticle

major histocompatibility complex
induced response
Histocompatibility
gene expression
lymphocytes

Reply to Haffner et al. DNA hypomethylation renders tumors more immunogenic

Stone, M. L., Chiappinelli, K. B., Li, H., Murphy, L. M., Travers, M. E., Topper, M. J., Mathios, D., Lim, M., Shih, I. M., Wang, T. L., Hung, C. F., Bhargava, V., Wiehagen, K. R., Cowley, G. S., Bachman, K. E., Strick, R., Strissel, P. L., Baylin, S. B. & Zahnow, C. A., Sep 11 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 37, p. E8583-E8584

Research output: Contribution to journalLetter

DNA
Neoplasms

Treatment with epigenetic agents profoundly inhibits tumor growth in leiomyosarcoma

Fischer, C. D. C., Hu, Y., Morreale, M., Lin, W. Y., Wali, A., Thakar, M., Karunasena, E., Sen, R., Cai, Y., Murphy, L., Zahnow, C. A., Keer, H., Thakar, M. & Ahuja, N., Apr 10 2018, In : Oncotarget. 9, 27, p. 19379-19395 17 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Epigenomics
Azacitidine
Growth
Neoplasms