Cindy James

Research output

Research output per year 1996 2017 2018 2019 2020 2021 2022 2024

• 149 Article
• 17 Review article
• 8 Letter
• 3 Comment/debate
• 4 More
  • 3 Editorial
  • 1 Chapter

Research output per year

Research output per year

Search results

• 2024

  How and Why to Organise Family-Based Screening Clinics for Hypertrophic Cardiomyopathy

  Rivers, B. J., Carrick, R. T., Muller, S. A., Barth, A., Madrazo, J. A. & James, C., 2024, (Accepted/In press) In: Canadian Journal of Cardiology.

  Research output: Contribution to journal › Article › peer-review
• 2023

  Arrhythmic risk stratification in arrhythmogenic right ventricular cardiomyopathy

  Gasperetti, A., James, C. A., Carrick, R. T., Protonotarios, A., Te Riele, A. S. J. M., Cadrin-Tourigny, J., Compagnucci, P., Duru, F., Van Tintelen, P., Elliot, P. M. & Calkins, H., Nov 1 2023, In: Europace. 25, 11, euad312.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Sudden Cardiac Death 38%
  • Implantable Defibrillators 20%
  • Cardiomyopathies 17%
  • Athletes 16%

• A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients

  Nagyova, E., Hoorntje, E. T., te Rijdt, W. P., Bosman, L. P., Syrris, P., Protonotarios, A., Elliott, P. M., Tsatsopoulou, A., Mestroni, L., Taylor, M. R. G., Sinagra, G., Merlo, M., Wada, Y., Horie, M., Mogensen, J., Christensen, A. H., Gerull, B., Song, L., Yao, Y., Fan, S., & 21 othersSaguner, A. M., Duru, F., Koskenvuo, J. W., Cruz Marino, T., Tichnell, C., Judge, D. P., Dooijes, D., Lekanne Deprez, R. H., Basso, C., Pilichou, K., Bauce, B., Wilde, A. A. M., Charron, P., Fressart, V., van der Heijden, J. F., van den Berg, M. P., Asselbergs, F. W., James, C. A., Jongbloed, J. D. H., Harakalova, M. & van Tintelen, J. P., Dec 2023, In: Journal of cardiovascular translational research. 16, 6, p. 1276-1286 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Composite Material 35%
  • Genes 28%
  • Virulence 15%
  • Cardiac Arrhythmias 15%

• Beyond gene-disease validity: capturing structured data on inheritance, allelic requirement, disease-relevant variant classes, and disease mechanism for inherited cardiac conditions

  Josephs, K. S., Roberts, A. M., Theotokis, P., Walsh, R., Ostrowski, P. J., Edwards, M., Fleming, A., Thaxton, C., Roberts, J. D., Care, M., Zareba, W., Adler, A., Sturm, A. C., Tadros, R., Novelli, V., Owens, E., Bronicki, L., Jarinova, O., Callewaert, B., Peters, S., & 15 othersLumbers, T., Jordan, E., Asatryan, B., Krishnan, N., Hershberger, R. E., Chahal, C. A. A., Landstrom, A. P., James, C., McNally, E. M., Judge, D. P., van Tintelen, P., Wilde, A., Gollob, M., Ingles, J. & Ware, J. S., Dec 2023, In: Genome Medicine. 15, 1, 86.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genes 100%
  • Datasets 65%
  • Inheritance Patterns 53%
  • Proteins 15%

• Diagnostic pitfalls in patients referred for arrhythmogenic right ventricular cardiomyopathy

  Sampognaro, J. R., Gaine, S. P., Sharma, A., Tichnell, C., Murray, B., Shaik, Z., Zimmerman, S. L., James, C. A., Gasperetti, A. & Calkins, H., Dec 2023, In: Heart Rhythm. 20, 12, p. 1720-1726 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Diagnostic Errors 34%
  • Implantable Defibrillators 30%
  • Syncope 19%
  • Magnetic Resonance Imaging 11%

• Exercise does not influence development of phenotype in PLN p.(Arg14del) cardiomyopathy

  van Lint, F. H. M., Hassanzada, F., Verstraelen, T. E., Wang, W., Bosman, L. P., van der Zwaag, P. A., Oomen, T., Calkins, H., Murray, B., Tichnell, C., Beuren, T. M. A., Asselbergs, F. W., Houweling, A., van den Berg, M. P., Wilde, A. A. M., James, C. A. & van Tintelen, J. P., Aug 2023, In: Netherlands Heart Journal. 31, 7-8, p. 291-299 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiomyopathies 92%
  • Exercise 61%
  • Cardiac Arrhythmias 60%
  • Phenotype 57%

• Lack of Evidence for the Role of the p.(Ser96Ala) Polymorphism in Histidine-Rich Calcium Binding Protein as a Secondary Hit in Cardiomyopathies

  van der Voorn, S. M., van Drie, E., Proost, V., Dimitrova, K., Ernst, R. F., James, C. A., Tichnell, C., Murray, B., Calkins, H., Saguner, A. M., Duru, F., Ellinor, P. T., Bezzina, C. R., Jurgens, S. J., van Tintelen, J. P. & van Veen, T. A. B., Nov 2023, In: International journal of molecular sciences. 24, 21, 15931.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carrier Proteins 100%
  • histidine 88%
  • polymorphism 80%
  • Polymorphism 78%
  • Calcium-Binding Proteins 78%

• Predicting ventricular tachycardia circuits in patients with arrhythmogenic right ventricular cardiomyopathy using genotype-specific heart digital twins

  Zhang, Y., Zhang, K., Prakosa, A., James, C., Zimmerman, S. L., Carrick, R., Sung, E., Gasperetti, A., Tichnell, C., Murray, B., Calkins, H. & Trayanova, N. A., 2023, In: eLife. 12, RP88865.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Twins 75%
  • Ventricular Tachycardia 75%
  • Disorder 60%
  • Velocity 59%

• Prognostic value of strain by feature-tracking cardiac magnetic resonance in arrhythmogenic right ventricular cardiomyopathy

  Bourfiss, M., Prakken, N. H. J., James, C. A., Planken, R. N., Boekholdt, S. M., Ahmetagic, D., Van Den Berg, M. P., Tichnell, C., Van Der Heijden, J. F., Loh, P., Murray, B., Tandri, H., Kamel, I., Calkins, H., Asselbergs, F. W., Zimmerman, S. L., Velthuis, B. K. & Te Riele, A. S. J. M., Jan 1 2023, In: European heart journal cardiovascular Imaging. 24, 1, p. 98-107 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiac Arrhythmias 60%
  • Magnetic Resonance Spectroscopy 59%
  • Statistics 11%
  • Ventricular Dysfunction 9%

• Subcutaneous and Transvenous Defibrillators in Arrhythmogenic Right Ventricular Cardiomyopathy: A Comparison of Clinical and Quality-of-Life Outcomes

  Wang, W., Gasperetti, A., Sears, S. F., Tichnell, C., Murray, B., Tandri, H., James, C. A. & Calkins, H., Mar 2023, In: JACC: Clinical Electrophysiology. 9, 3, p. 394-402 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Defibrillators 85%
  • Implantable Defibrillators 81%
  • Quality of Life 45%
  • Shock 26%

• Vigorous Exercise in Patients with Hypertrophic Cardiomyopathy

  Lampert, R., Ackerman, M. J., Marino, B. S., Burg, M., Ainsworth, B., Salberg, L., Tome Esteban, M. T., Ho, C. Y., Abraham, R., Balaji, S., Barth, C., Berul, C. I., Bos, M., Cannom, D., Choudhury, L., Concannon, M., Cooper, R., Czosek, R. J., Dubin, A. M., Dziura, J., & 24 othersEidem, B., Emery, M. S., Estes, N. A. M., Etheridge, S. P., Geske, J. B., Gray, B., Hall, K., Harmon, K. G., James, C. A., Lal, A. K., Law, I. H., Li, F., Link, M. S., McKenna, W. J., Molossi, S., Olshansky, B., Ommen, S. R., Saarel, E. V., Saberi, S., Simone, L., Tomaselli, G., Ware, J. S., Zipes, D. P. & Day, S. M., Jun 14 2023, In: JAMA cardiology. 8, 6, p. 595-605 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hypertrophic Cardiomyopathy 100%
  • Exercise 56%
  • Cardiac Arrhythmias 20%
  • Genotype 11%
  • Cohort Studies 10%
• 2022

  A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy

  Cadrin-Tourigny, J., Bosman, L. P., Nozza, A., Wang, W., Tadros, R., Bhonsale, A., Bourfiss, M., Fortier, A., Lie, Ø. H., Saguner, A. M., Svensson, A., Andorin, A., Tichnell, C., Murray, B., Zeppenfeld, K., Van Den Berg, M. P., Asselbergs, F. W., Wilde, A. A. M., Krahn, A. D., Talajic, M., & 20 othersRivard, L., Chelko, S., Zimmerman, S. L., Kamel, I. R., Crosson, J. E., Judge, D. P., Yap, S. C., Van Der Heijden, J. F., Tandri, H., Jongbloed, J. D. H., Guertin, M. C., Van Tintelen, J. P., Platonov, P. G., Duru, F., Haugaa, K. H., Khairy, P., Hauer, R. N. W., Calkins, H., Te Riele, A. S. J. M. & James, C. A., Aug 21 2022, In: European heart journal. 43, 32, p. E1-E9

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiac Arrhythmias 60%
  • Sudden Cardiac Death 55%
  • Implantable Defibrillators 35%
  • Optimism 24%

• Arrhythmic risk prediction in arrhythmogenic right ventricular cardiomyopathy: external validation of the arrhythmogenic right ventricular cardiomyopathy risk calculator

  Jordà, P., Bosman, L. P., Gasperetti, A., Mazzanti, A., Gourraud, J. B., Davies, B., Frederiksen, T. C., Weidmann, Z. M., Di Marco, A., Roberts, J. D., Macintyre, C., Seifer, C., Delinière, A., Alqarawi, W., Kukavica, D., Minois, D., Trancuccio, A., Arnaud, M., Targetti, M., Martino, A., & 21 othersOliviero, G., Pipilas, D. C., Carbucicchio, C., Compagnucci, P., Dello Russo, A., Olivotto, I., Calò, L., Lubitz, S. A., Cutler, M. J., Chevalier, P., Arbelo, E., Priori, S. G., Healey, J. S., Calkins, H., Casella, M., Jensen, H. K., Tondo, C., Tadros, R., James, C. A., Krahn, A. D. & Cadrin-Tourigny, J., Aug 21 2022, In: European heart journal. 43, 32, p. 3041-3052 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Implantable Defibrillators 46%
  • Consensus 38%
  • Cardiac Arrhythmias 34%
  • Sudden Cardiac Death 33%

• Arrhythmogenic Right Ventricular Cardiomyopathy Prevalence and Arrhythmic Outcomes in At-Risk Family Members: A Systematic Review and Meta-Analysis

  Sharma, A., Bosman, L. P., Tichnell, C., Nanavati, J., Murray, B., Nonyane, B. A. S., Tandri, H., Calkins, H. & James, C. A., Jun 1 2022, In: Circulation. Genomic and precision medicine. 15, 3, p. E003530

  Research output: Contribution to journal › Review article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Meta-Analysis 53%
  • Cardiac Arrhythmias 52%
  • Systematic Reviews 52%
  • Advisory Committees 28%

• Association of Premature Ventricular Contraction Burden on Serial Holter Monitoring with Arrhythmic Risk in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy

  Gasperetti, A., Cappelletto, C., Carrick, R., Targetti, M., Tichnell, C., Martino, A., Murray, B., Compagnucci, P., Stolfo, D., Bisson, J., Gilotra, N., Carbucicchio, C., Olivotto, I., Tandri, H., Dello Russo, A., Cadrin-Tourigny, J., Calò, L., Tondo, C., Sinagra, G., James, C. A., & 2 othersCasella, M. & Calkins, H., Apr 2022, In: JAMA cardiology. 7, 4, p. 378-385 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Ambulatory Electrocardiography 88%
  • Ventricular Premature Complexes 85%
  • Cardiac Arrhythmias 30%
  • Arrhythmogenic Right Ventricular Dysplasia, Familial, 6 13%

• Clinical characteristics and risk stratification of desmoplakin cardiomyopathy

  Wang, W., Murray, B., Tichnell, C., Gilotra, N. A., Zimmerman, S. L., Gasperetti, A., Scheel, P., Tandri, H., Calkins, H. & James, C. A., Feb 1 2022, In: Europace. 24, 2, p. 268-277 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Desmoplakins 100%
  • Cardiomyopathies 62%
  • Cardiac Arrhythmias 54%
  • Heart Failure 39%
  • Confidence Intervals 25%

• Comparing clinical performance of current implantable cardioverter-defibrillator implantation recommendations in arrhythmogenic right ventricular cardiomyopathy

  Bosman, L. P., Nielsen Gerlach, C. L., Cadrin-Tourigny, J., Orgeron, G., Tichnell, C., Murray, B., Bourfiss, M., Van Der Heijden, J. F., Yap, S. C., Zeppenfeld, K., Van Den Berg, M. P., Wilde, A. A. M., Asselbergs, F. W., Tandri, H., Calkins, H., Van Tintelen, J. P., James, C. A. & Te Riele, A. S. J. M., Feb 1 2022, In: Europace. 24, 2, p. 296-305 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Implantable Defibrillators 81%
  • Cardiac Arrhythmias 60%
  • Decision Support Techniques 12%
  • Advisory Committees 5%

• Genotype-Based Risk Stratification Can Outperform Phenotype-Based Practice for Inherited Cardiomyopathies: Not All Paths Are Equal

  James, C. A. & Gasperetti, A., Nov 22 2022, In: Journal of the American College of Cardiology. 80, 21, p. 1995-1997 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Genotype–phenotype Correlates in Arrhythmogenic Cardiomyopathies

  Murray, B. & James, C. A., Nov 2022, In: Current Cardiology Reports. 24, 11, p. 1557-1565 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cardiomyopathies 100%
  • Arrhythmogenic Right Ventricular Dysplasia 43%
  • Cardiac Arrhythmias 26%
  • Electrocardiography 25%
  • Genetic Testing 21%

• Heart transplantation strategies in arrhythmogenic right ventricular cardiomyopathy: a tertiary ARVC centre experience

  Scheel, P. J., Giuliano, K., Tichnell, C., James, C., Murray, B., Tandri, H., Carter, D., Fehr, T., Umapathi, P., Vaishnav, J., Lewsey, S. C., Hsu, S., Calkins, H., Sharma, K., Choi, C. W., Gilotra, N. A. & Kilic, A., Apr 2022, In: ESC Heart Failure. 9, 2, p. 1008-1017 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Heart Transplantation 75%
  • Transplants 39%
  • Cardiac Arrhythmias 30%
  • Registries 21%

• Integrating Exercise into Personalized Ventricular Arrhythmia Risk Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy

  Bosman, L. P., Wang, W., Lie, Ø. H., Van Lint, F. H. M., Rootwelt-Norberg, C., Murray, B., Tichnell, C., Cadrin-Tourigny, J., Van Tintelen, J. P., Asselbergs, F. W., Calkins, H., Te Riele, A. S. J. M., Haugaa, K. H. & James, C. A., Feb 1 2022, In: Circulation: Arrhythmia and Electrophysiology. 15, 2, p. E010221

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiac Arrhythmias 60%
  • Exercise 46%
  • Arrhythmogenic Right Ventricular Dysplasia, Familial, 3 17%
  • Athletes 7%

• Longitudinal Prediction of Ventricular Arrhythmic Risk in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy

  Carrick, R. T., Te Riele, A. S. J. M., Gasperetti, A., Bosman, L., Muller, S. A., Pendleton, C., Tichnell, C., Murray, B., Yap, S. C., Van Den Berg, M. P., Wilde, A., Zeppenfeld, K., Hays, A., Zimmerman, S. L., Tandri, H., Cadrin-Tourigny, J., Van Tintelen, P., Calkins, H., James, C. A. & Wu, K. C., Nov 1 2022, In: Circulation: Arrhythmia and Electrophysiology. 15, 11, p. E011207

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiac Arrhythmias 51%
  • Ventricular Premature Complexes 12%
  • Statistics 11%
  • Ventricular Tachycardia 10%

• Loss-of-Function FLNC Variants Are Associated with Arrhythmogenic Cardiomyopathy Phenotypes When Identified Through Exome Sequencing of a General Clinical Population

  Carruth, E. D., Qureshi, M., Alsaid, A., Kelly, M. A., Calkins, H., Murray, B., Tichnell, C., Sturm, A. C., Baras, A., Lester Kirchner, H., Fornwalt, B. K., James, C. A. & Haggerty, C. M., Aug 1 2022, In: Circulation: Cardiovascular Genetics. 15, 4, p. 278-286 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exome 100%
  • Cardiomyopathies 81%
  • Odds Ratio 53%
  • Phenotype 50%
  • Population 32%

• Multimodality Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy

  Malik, N., Mukherjee, M., Wu, K. C., Zimmerman, S. L., Zhan, J., Calkins, H., James, C. A., Gilotra, N. A., Sheikh, F. H., Tandri, H., Kutty, S. & Hays, A. G., Feb 1 2022, In: Circulation: Cardiovascular Imaging. 15, 2, p. E013725

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Echocardiography 35%
  • Heart Ventricles 25%
  • Magnetic Resonance Spectroscopy 23%
  • Right Ventricular Function 17%

• Programmed Ventricular Stimulation as an Additional Primary Prevention Risk Stratification Tool in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Study

  Gasperetti, A., Carrick, R. T., Costa, S., Compagnucci, P., Bosman, L. P., Chivulescu, M., Tichnell, C., Murray, B., Tandri, H., Tadros, R., Rivard, L., Van Den Berg, M. P., Zeppenfeld, K., Wilde, A. A. M., Pompilio, G., Carbucicchio, C., Dello Russo, A., Casella, M., Svensson, A., Brunckhorst, C. B., & 11 othersVan Tintelen, J. P., Platonov, P. G., Haugaa, K. H., Duru, F., Te Riele, A. S. J. M., Khairy, P., Tondo, C., Calkins, H., James, C. A., Saguner, A. M. & Cadrin-Tourigny, J., Nov 8 2022, In: Circulation. 146, 19, p. 1434-1443 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Primary Prevention 73%
  • Cardiac Arrhythmias 43%
  • Ventricular Tachycardia 20%
  • Arrhythmogenic Right Ventricular Dysplasia, Familial, 6 14%

• Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: A translational study

  Cerrone, M., Marrón-Liñares, G. M., Van Opbergen, C. J. M., Costa, S., Bourfiss, M., Perez-Hernández, M., Schlamp, F., Sanchis-Gomar, F., Malkani, K., Drenkova, K., Zhang, M., Lin, X., Heguy, A., Velthuis, B. K., Prakken, N. H. J., Lagerche, A., Calkins, H., James, C. A., Te Riele, A. S. J. M. & Delmar, M., Mar 21 2022, In: European heart journal. 43, 12, p. 1251-1264 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Plakophilins 100%
  • Arrhythmogenic Right Ventricular Dysplasia 83%
  • Exercise 38%
  • Cardiomyopathies 28%
  • Endurance Training 18%

• Strength of the genetic counselor: patient relationship is associated with extent of increased empowerment in patients with arrhythmogenic cardiomyopathy

  Murray, B., Tichnell, C., Burch, A. E., Calkins, H. & James, CA., Apr 2022, In: Journal of Genetic Counseling. 31, 2, p. 388-397 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Counselors 100%
  • Patient Participation 97%
  • Genetic Counseling 93%
  • Cardiomyopathies 83%
  • Anxiety 26%

• Sudden cardiac death risk prediction in arrhythmogenic right ventricular cardiomyopathy: a practical approach to navigating the challenges of prediction models

  Cadrin-Tourigny, J., Bosman, L. P. & James, C. A., Dec 14 2022, In: European heart journal. 43, 47, p. 4961-4962 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• 2021

  2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families

  Stiles, M. K., Wilde, A. A. M., Abrams, D. J., Ackerman, M. J., Albert, C. M., Behr, E. R., Chugh, S. S., Cornel, M. C., Gardner, K., Ingles, J., James, C. A., Juang, J. M. J., Kääb, S., Kaufman, E. S., Krahn, A. D., Lubitz, S. A., MacLeod, H., Morillo, C. A., Nademanee, K., Probst, V., & 8 othersSaarel, E. V., Sacilotto, L., Semsarian, C., Sheppard, M. N., Shimizu, W., Skinner, J. R., Tfelt-Hansen, J. & Wang, D. W., Jun 2021, In: journal of arrhythmia. 37, 3, p. 481-534 54 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sudden Cardiac Death 100%
  • Sudden Death 95%
  • Consensus 87%
  • Heart 59%
  • Committee Membership 18%

• 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families

  Stiles, M. K., Wilde, A. A. M., Abrams, D. J., Ackerman, M. J., Albert, C. M., Behr, E. R., Chugh, S. S., Cornel, M. C., Gardner, K., Ingles, J., James, C. A., Jimmy Juang, J. M., Kääb, S., Kaufman, E. S., Krahn, A. D., Lubitz, S. A., MacLeod, H., Morillo, C. A., Nademanee, K., Probst, V., & 8 othersSaarel, E. V., Sacilotto, L., Semsarian, C., Sheppard, M. N., Shimizu, W., Skinner, J. R., Tfelt-Hansen, J. & Wang, D. W., Jan 2021, In: Heart Rhythm. 18, 1, p. e1-e50

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sudden Cardiac Death 100%
  • Sudden Death 95%
  • Consensus 87%
  • Heart 59%
  • Committee Membership 18%
  13 Scopus citations

• Altered electrical, biomolecular, and immunologic phenotypes in a novel patient-derived stem cell model of Desmoglein-2 mutant ARVC

  Hawthorne, R. N., Blazeski, A., Lowenthal, J., Kannan, S., Teuben, R., Disilvestre, D., Morrissette-Mcalmon, J., Saffitz, J. E., Boheler, K. R., James, C. A., Chelko, S. P., Tomaselli, G. & Tung, L., Jul 2 2021, In: Journal of Clinical Medicine. 10, 14, 3061.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Desmoglein 2 100%
  • Arrhythmogenic Right Ventricular Dysplasia 79%
  • Induced Pluripotent Stem Cells 51%
  • Stem Cells 41%
  • Phenotype 34%

• Anxiety and depression in inherited channelopathy patients with implantable cardioverter-defibrillators

  Singh, S. M., Murray, B., Tichnell, C., McClellan, R., James, C. A. & Barth, A. S., Aug 2021, In: Heart Rhythm O2. 2, 4, p. 388-393 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Channelopathies 100%
  • Implantable Defibrillators 81%
  • Anxiety 50%
  • Equipment and Supplies 16%
  • Shock 14%

• Arrhythmogenic right ventricular cardiomyopathy and sports activity: From molecular pathways in diseased hearts to new insights into the athletic heart mimicry

  Gasperetti, A., James, C. A., Cerrone, M., Delmar, M., Calkins, H. & Duru, F., 2021, In: European heart journal. 42, 13, p. 1231-1243 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Sports 62%
  • Heart Diseases 57%
  • Exercise 46%
  • Heart 46%
  1 Scopus citations

• Arrhythmogenic Right Ventricular Cardiomyopathy in Pediatric Patients: An Important but Underrecognized Clinical Entity

  te Riele, A. S. J. M., James, C. A., Calkins, H. & Tsatsopoulou, A., Dec 2 2021, In: Frontiers in Pediatrics. 9, 750916.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Pediatrics 45%
  • Sudden Cardiac Death 22%
  • Naxos disease 20%
  • LEOPARD Syndrome 17%

• Arrhythmogenic Right Ventricular Cardiomyopathy Presenting as Clinical Myocarditis in Women

  Scheel, P. J., Murray, B., Tichnell, C., James, C. A., Tandri, H., Calkins, H., Chelko, S. & Gilotra, N. A., Apr 15 2021, In: American Journal of Cardiology. 145, p. 128-134 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Myocarditis 80%
  • Desmoplakins 30%
  • Advisory Committees 13%
  • Genetic Testing 13%

• Cadherin 2-Related Arrhythmogenic Cardiomyopathy: Prevalence and Clinical Features

  Ghidoni, A., Elliott, P. M., Syrris, P., Calkins, H., James, C. A., Judge, D. P., Murray, B., Barc, J., Probst, V., Schott, J. J., Song, J. P., Hauer, R. N. W., Hoorntje, E. T., Van Tintelen, J. P., Schulze-Bahr, E., Hamilton, R. M., Mittal, K., Semsarian, C., Behr, E. R., Ackerman, M. J., & 7 othersBasso, C., Parati, G., Gentilini, D., Kotta, M. C., Mayosi, B. M., Schwartz, P. J. & Crotti, L., Apr 1 2021, In: Circulation: Cardiovascular Genetics. 14, 2, p. E003097

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cadherins 100%
  • Cardiomyopathies 96%
  • Genetic Testing 25%
  • Heart Ventricles 21%
  • Cardiac Arrhythmias 20%
  1 Scopus citations

• Clinical Findings and Diagnostic Yield of Arrhythmogenic Cardiomyopathy Through Genomic Screening of Pathogenic or Likely Pathogenic Desmosome Gene Variants

  Carruth, E. D., Beer, D., Alsaid, A., Schwartz, M. L. B., McMinn, M., Kelly, M. A., Buchanan, A. H., Nevius, C. D., Calkins, H., James, C. A., Murray, B., Tichnell, C., Matsumura, M. E., Kirchner, H. L., Fornwalt, B. K., Sturm, A. C. & Haggerty, C. M., Apr 1 2021, In: Circulation: Cardiovascular Genetics. 14, 2, p. E003302

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Desmosomes 100%
  • Cardiomyopathies 75%
  • Genes 31%
  • Arrhythmogenic Right Ventricular Dysplasia 31%
  • Defibrillators 13%

• Clinical outcomes of catheter ablation of ventricular tachycardia in patients with arrhythmogenic right ventricular cardiomyopathy: Insights from the Johns Hopkins ARVC Program

  Daimee, U. A., Assis, F. R., Murray, B., Tichnell, C., James, C. A., Calkins, H. & Tandri, H., Aug 2021, In: Heart Rhythm. 18, 8, p. 1369-1376 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Catheter Ablation 81%
  • Ventricular Tachycardia 75%
  • Anti-Arrhythmia Agents 18%
  • Survival 12%

• Contemporary and Future Approaches to Precision Medicine in Inherited Cardiomyopathies: JACC Focus Seminar 3/5

  Fatkin, D., Calkins, H., Elliott, P., James, C. A., Peters, S. & Kovacic, J. C., May 25 2021, In: Journal of the American College of Cardiology. 77, 20, p. 2551-2572 22 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Precision Medicine 100%
  • Cardiomyopathies 90%
  • Population Biological Variation 28%
  • Treatment Failure 22%
  • Genetic Variation 22%

• Correction to: The genetic architecture of Plakophilin 2 cardiomyopathy (Genetics in Medicine, (2021), 23, 10, (1961-1968), 10.1038/s41436-021-01233-7)

  Regeneron Genetics Center, Oct 2021, In: Genetics in Medicine. 23, 10, p. 2014 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Plakophilins 100%
  • Baltimore 75%
  • Medical Schools 61%
  • Cardiology 58%
  • Cardiomyopathies 57%

• Efficacy of catheter ablation for atrial arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy—a multicenter study

  Gasperetti, A., James, C. A., Chen, L., Schenker, N., Casella, M., Kany, S., Mathew, S., Compagnucci, P., Müssigbrodt, A., Jensen, H. K., Svensson, A., Costa, S., Forleo, G. B., Platonov, P. G., Tondo, C., Song, J. P., Russo, A. D., Ruschitzka, F., Brunckhorst, C., Calkins, H., & 2 othersDuru, F. & Saguner, A. M., Nov 1 2021, In: Journal of Clinical Medicine. 10, 21, 4962.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Catheter Ablation 100%
  • Arrhythmogenic Right Ventricular Dysplasia 81%
  • Multicenter Studies 75%
  • Cardiac Arrhythmias 73%
  • Tachycardia 37%

• Efficacy of catheter ablation for premature ventricular contractions in arrhythmogenic right ventricular cardiomyopathy

  Assis, F. R., Sharma, A., Daimee, U. A., Murray, B., Tichnell, C., Agafonova, J., James, C. A., Calkins, H. & Tandri, H., Jun 2021, In: Journal of cardiovascular electrophysiology. 32, 6, p. 1665-1674 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Ventricular Premature Complexes 85%
  • Catheter Ablation 81%
  • Ventricular Tachycardia 10%
  • Anti-Arrhythmia Agents 5%

• Evidence-Based Assessment of Genes in Dilated Cardiomyopathy

  Jordan, E., Peterson, L., Ai, T., Asatryan, B., Bronicki, L., Brown, E., Celeghin, R., Edwards, M., Fan, J., Ingles, J., James, C. A., Jarinova, O., Johnson, R., Judge, D. P., Lahrouchi, N., Lekanne Deprez, R. H., Lumbers, R. T., Mazzarotto, F., Medeiros Domingo, A., Miller, R. L., & 14 othersMorales, A., Murray, B., Peters, S., Pilichou, K., Protonotarios, A., Semsarian, C., Shah, P., Syrris, P., Thaxton, C., Van Tintelen, J. P., Walsh, R., Wang, J., Ware, J. & Hershberger, R. E., Jul 6 2021, In: Circulation. 144, 1, p. 7-19 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dilated Cardiomyopathy 100%
  • Genes 36%
  • Hypertrophic Cardiomyopathy 15%
  • Genetic Testing 14%
  • Arrhythmogenic Right Ventricular Dysplasia 12%

• Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy

  Chelko, S. P., Keceli, G., Carpi, A., Doti, N., Agrimi, J., Asimaki, A., Beti, C. B., Miyamoto, M., Amat-Codina, N., Bedja, D., Wei, A. C., Murray, B., Tichnell, C., Kwon, C., Calkins, H., James, C. A., O'Rourke, B., Halushka, M. K., Melloni, E., Saffitz, J. E., & 6 othersJudge, D. P., Ruvo, M., Kitsis, R. N., Andersen, P., Di Lisa, F. & Paolocci, N., Feb 17 2021, In: Science translational medicine. 13, 581, eabf0891.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apoptosis Inducing Factor 100%
  • Calpain 87%
  • Cardiomyopathies 69%
  • Muscle Cells 65%
  • Cell Death 53%
  2 Scopus citations

• Global approaches to cardiogenetic evaluation after sudden cardiac death in the young: A survey among health care professionals

  van den Heuvel, L. M., Do, J., Yeates, L., MacLeod, H., James, C. A., Duflou, J., Skinner, J. R., Semsarian, C., van Tintelen, J. P. & Ingles, J., Oct 2021, In: Heart Rhythm. 18, 10, p. 1637-1644 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Health Care Surveys 100%
  • Sudden Cardiac Death 81%
  • Genetic Testing 76%
  • New Zealand 22%
  • Delivery of Health Care 19%

• Impact of Genetic Variant Reassessment on the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy Based on the 2010 Task Force Criteria

  Costa, S., Medeiros-Domingo, A., Gasperetti, A., Akdis, D., Berger, W., James, C. A., Ruschitzka, F., Brunckhorst, C. B., Duru, F. & Saguner, A. M., Feb 1 2021, In: Circulation. Genomic and precision medicine. 14, 1, p. E003047

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Advisory Committees 75%
  • Plakophilins 68%
  • Virulence 17%
  • Medical Genetics 13%
  1 Scopus citations

• International Evidence Based Reappraisal of Genes Associated With Arrhythmogenic Right Ventricular Cardiomyopathy Using the Clinical Genome Resource Framework

  James, C. A., Jongbloed, J. D. H., Hershberger, R. E., Morales, A., Judge, D. P., Syrris, P., Pilichou, K., Domingo, A. M., Murray, B., Cadrin-Tourigny, J., Deprez, R. L., Celeghin, R., Protonotarios, A., Asatryan, B., Brown, E., Jordan, E., McGlaughon, J., Thaxton, C., Kurtz, C. L. & Van Tintelen, J. P., Jun 1 2021, In: Circulation: Cardiovascular Genetics. 14, 3, p. E003273

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Genome 48%
  • Genes 28%
  • Polymorphic catecholergic ventricular tachycardia 6%
  • Ventricular Dysfunction 5%

• Keeping balance: Author's reply

  Bosman, L. P., Cadrin-Tourigny, J., James, C. A. & Te Riele, A. S. J. M., Jan 1 2021, In: Europace. 23, 1, p. 157-158 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Left ventricular fibro-fatty replacement in arrhythmogenic right ventricular dysplasia/cardiomyopathy: prevalence, patterns, and association with arrhythmias

  Zghaib, T., Te Riele, A. S. J. M., James, C. A., Rastegar, N., Murray, B., Tichnell, C., Halushka, M. K., Bluemke, D. A., Tandri, H., Calkins, H., Kamel, I. R. & Zimmerman, S. L., Dec 2021, In: Journal of Cardiovascular Magnetic Resonance. 23, 1, 58.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Cardiac Arrhythmias 60%
  • Magnetic Resonance Spectroscopy 59%
  • Gadolinium 22%
  • Advisory Committees 21%

• Phenotypic Expression, Natural History, and Risk Stratification of Cardiomyopathy Caused by Filamin C Truncating Variants

  Gigli, M., Stolfo, D., Graw, S. L., Merlo, M., Gregorio, C., Nee Chen, S., Dal Ferro, M., Paldinomd, A., De Angelis, G., Brun, F., Jirikowic, J., Salcedo, E. E., Turja, S., Fatkin, D., Johnson, R., Van Tintelen, J. P., Te Riele, A. S. J. M., Wilde, A. A. M., Lakdawala, N. K., Picard, K., & 16 othersMiani, D., Muser, D., Maria Severini, G., Calkins, H., James, C. A., Murray, B., Tichnell, C., Parikh, V. N., Ashley, E. A., Reuter, C., Song, J., Judge, D. P., McKenna, W. J., Taylor, M. R. G., Sinagra, G. & Mestroni, L., Nov 16 2021, In: Circulation. 144, 20, p. 1600-1611 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Filamins 100%
  • Natural History 67%
  • Cardiomyopathies 65%
  • Cardiac Arrhythmias 35%
  • Sudden Cardiac Death 27%