Colleen Hanrahan

Assistant Scientist

20002019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2000 2019

2019

Contact tracing versus facility-based screening for active TB case finding in rural South Africa: A pragmatic cluster-randomized trial (Kharitode TB)

Hanrahan, C., Nonyane, B. A. S., Mmolawa, L., West, N. S., Siwelana, T., Lebina, L., Martinson, N. & Dowdy, D. W., Apr 1 2019, In : PLoS medicine. 16, 4, p. e1002796

Research output: Contribution to journalArticle

Open Access
Contact Tracing
South Africa
Tuberculosis
Confidence Intervals
Therapeutics

Health system barriers to implementation of TB preventive strategies in South African primary care facilities

Van Ginderdeuren, E., Bassett, J., Hanrahan, C., Mutunga, L. & Van Rie, A., Feb 1 2019, In : PloS one. 14, 2, e0212035.

Research output: Contribution to journalArticle

Open Access
isoniazid
Isoniazid
Primary Health Care
Health
tuberculin

Mental health in South African adolescents living with HIV

West, N., Schwartz, S., Mudavanhu, M., Hanrahan, C., France, H., Nel, J., Mutunga, L., Bernhardt, S., Bassett, J. & Van Rie, A., Jan 1 2019, In : AIDS care. 31, 1, p. 117-124 8 p.

Research output: Contribution to journalArticle

Mental Health
mental health
HIV
adolescent
Social Support

Perceptions of Community and Clinic-Based Adherence Clubs for Patients Stable on Antiretroviral Treatment: A Mixed Methods Study

Mudavanhu, M., West, N. S., Schwartz, S. R., Mutunga, L., Keyser, V., Bassett, J., Van Rie, A. & Hanrahan, C. F., Jan 1 2019, (Accepted/In press) In : AIDS and behavior.

Research output: Contribution to journalArticle

Patient Compliance
Health Services Accessibility
Therapeutics
South Africa
Social Support

Promoting Tuberculosis Preventive Therapy for People Living with HIV in South Africa: Interventions Hindered by Complicated Clinical Guidelines and Imbalanced Patient-Provider Dynamics

Jarrett, B. A., Woznica, D. M., Tilchin, C., Mpungose, N., Motlhaoleng, K., Golub, J. E., Martinson, N. A. & Hanrahan, C. F., Jan 1 2019, (Accepted/In press) In : AIDS and behavior.

Research output: Contribution to journalArticle

South Africa
Isoniazid
Tuberculosis
HIV
Guidelines

Risk factors for catastrophic costs associated with tuberculosis in rural South Africa

Stracker, N., Hanrahan, C., Mmolawa, L., Nonyane, B. A. S., Tampi, R., Tucker, A., West, N., Lebina, L., Martinson, N. & Dowdy, D. W., Jun 1 2019, In : The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 23, 6, p. 756-763 8 p.

Research output: Contribution to journalArticle

South Africa
Tuberculosis
Costs and Cost Analysis
Unemployment
Northern Africa

The impact of community- versus clinic-based adherence clubs on loss from care and viral suppression for antiretroviral therapy patients: Findings from a pragmatic randomized controlled trial in South Africa

Hanrahan, C., Schwartz, S., Mudavanhu, M., West, N. S., Mutunga, L., Keyser, V., Bassett, J. & Van Rie, A., May 1 2019, In : PLoS medicine. 16, 5, p. e1002808

Research output: Contribution to journalArticle

Open Access
South Africa
Randomized Controlled Trials
Therapeutics
CD4 Lymphocyte Count
Viral Load

Tuberculosis patients with higher levels of poverty face equal or greater costs of illness

Erlinger, S., Stracker, N., Hanrahan, C., Nonyane, B. A. S., Mmolawa, L., Tampi, R., Tucker, A., West, N., Lebina, L., Martinson, N. A. & Dowdy, D., Nov 1 2019, In : International Journal of Tuberculosis and Lung Disease. 23, 11, p. 1205-1212 8 p.

Research output: Contribution to journalArticle

Cost of Illness
Poverty
Tuberculosis
Costs and Cost Analysis
South Africa
2018

Chest X-ray for tuberculosis preventive therapy: use caution

Hanrahan, C. & Dowdy, D. W., Sep 1 2018, In : The Lancet HIV. 5, 9, p. e478-e479

Research output: Contribution to journalComment/debate

Tuberculosis
Thorax
X-Rays
Therapeutics
Isoniazid
South Africa
Cost-Benefit Analysis
Pregnant Women
HIV

Diagnostic strategies for childhood tuberculosis in the context of primary care in a high-burden setting: the value of alternative sampling methods

Hanrahan, C., Dansey, H., Mutunga, L., France, H., Omar, S. V., Ismail, N., Bassett, J. & Van Rie, A., Jan 1 2018, (Accepted/In press) In : Paediatrics and international child health.

Research output: Contribution to journalArticle

Primary Health Care
Tuberculosis
Tuberculin
HIV
Sputum

Maternal Motivation to Take Preventive Therapy in Antepartum and Postpartum Among HIV-Positive Pregnant Women in South Africa: A Choice Experiment

Kim, H. Y., Dowdy, D. W., Martinson, N. A., Kerrigan, D., Tudor, C., Golub, J. E., Bridges, J. F. P. & Hanrahan, C., Jan 1 2018, (Accepted/In press) In : AIDS and Behavior.

Research output: Contribution to journalArticle

South Africa
Postpartum Period
Motivation
Pregnant Women
Mothers
South Africa
Postpartum Period
Pregnant Women
Mothers
HIV

Opportunistic diseases diminish the clinical benefit of immediate co-infected antiretroviral adults with therapy low CD4 in HIV-tuberculosis R cell counts

Worodria, W., Ssempijja, V., Hanrahan, C., Ssegonja, R., Muhofwa, A., Mazapkwe, D., Mayanja-Kizza, H., Reynolds, S. J., Colebunders, R. & Manabe, Y. C., Jan 1 2018, In : AIDS. 32, 15, p. 2141-2149 9 p.

Research output: Contribution to journalArticle

Tuberculosis
Cell Count
HIV
Mortality
CD4 Lymphocyte Count

The effect of partner HIV status on motivation to take antiretroviral and isoniazid preventive therapies: a conjoint analysis

Kim, H. Y., Hanrahan, C., Dowdy, D. W., Martinson, N., Golub, J. E. & Bridges, J. F. P., Mar 29 2018, (Accepted/In press) In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. p. 1-8 8 p.

Research output: Contribution to journalArticle

Isoniazid
Motivation
HIV
Therapeutics
Patient-Centered Care

The unmet needs and health priorities of the urban poor: Generating the evidence base for urban community health worker programmes in South Africa

van Rie, A., West, N. S., Schwartz, S., Mutunga, L., Hanrahan, C., Ncayiyana, J. & Bassett, J., Sep 1 2018, In : South African Medical Journal. 108, 9, p. 734-740 7 p.

Research output: Contribution to journalArticle

Urban Health
Health Priorities
South Africa
Violence
Health
2017
Health Facilities
Tuberculosis
HIV
Delivery of Health Care
Health
South Africa
Tuberculosis
Research
Focus Groups
Motivation
2016

Ancient disease, modern epidemiology: A century of progress in understanding and fighting tuberculosis

Zwerling, A., Hanrahan, C. & Dowdy, D. W., Mar 1 2016, In : American Journal of Epidemiology. 183, 5, p. 407-414 8 p.

Research output: Contribution to journalArticle

Epidemiology
Tuberculosis
Vaccines
Epidemiologic Methods
Confounding Factors (Epidemiology)

Higher cost of implementing Xpert® MTB/RIF in Ugandan peripheral settings: Implications for cost-effectiveness

Hsiang, E., Little, K. M., Haguma, P., Hanrahan, C., Katamba, A., Cattamanchi, A., Davis, J. L., Vassall, A. & Dowdy, D. W., Sep 1 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 9

Research output: Contribution to journalArticle

Cost-Benefit Analysis
Costs and Cost Analysis
Tuberculosis
Uganda
Budgets

Implementation of Xpert MTB/RIF in Uganda: Missed opportunities to improve diagnosis of tuberculosis

Hanrahan, C., Haguma, P., Ochom, E., Kinera, I., Cobelens, F., Cattamanchi, A., Davis, L., Katamba, A. & Dowdy, D. W., Apr 1 2016, In : Open Forum Infectious Diseases. 3, 2, ofw068.

Research output: Contribution to journalArticle

Uganda
Tuberculosis
Therapeutics
Confidence Intervals
Health Facilities

Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults

Shah, M., Hanrahan, C., Wang, Z. Y., Dendukuri, N., Lawn, S. D., Denkinger, C. M. & Steingart, K. R., May 10 2016, In : The Cochrane database of systematic reviews. 2016, 5, CD011420.

Research output: Contribution to journalArticle

Tuberculosis
HIV
Urine
Sputum
lipoarabinomannan

Prevalence of latent tuberculosis infection and predictive factors in an urban informal settlement in Johannesburg, South Africa: A cross-sectional study

Ncayiyana, J. R., Bassett, J., West, N., Westreich, D., Musenge, E., Emch, M., Pettifor, A., Hanrahan, C., Schwartz, S., Sanne, I. & van Rie, A., Nov 8 2016, In : BMC Infectious Diseases. 16, 1, 661.

Research output: Contribution to journalArticle

Latent Tuberculosis
South Africa
Cross-Sectional Studies
HIV
Logistic Models
2015

The patient impact of point-of-care vs. Laboratory placement of XpertW MTB/RIF

Hanrahan, C., Clouse, K., Bassett, J., Mutunga, L., Selibas, K., Stevens, W., Scott, L., Sanne, I. & Van Rie, A., Jul 1 2015, In : International Journal of Tuberculosis and Lung Disease. 19, 7, p. 811-816 6 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Tuberculosis
Therapeutics
South Africa
Pulmonary Tuberculosis
2014
Administrative Personnel
Coinfection
Pulmonary Tuberculosis
HIV Infections
Tuberculosis

A home tracing program for contacts of people with tuberculosis or HIV and patients lost to care

Deery, C. B., Hanrahan, C., Selibas, K., Bassett, J., Sanne, I. & Van Rie, A., May 1 2014, In : International Journal of Tuberculosis and Lung Disease. 18, 5

Research output: Contribution to journalArticle

Contact Tracing
Tuberculosis
HIV
Isoniazid
Therapeutics

Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments

Theron, G., Peter, J., Calligaro, G., Meldau, R., Hanrahan, C., Khalfey, H., Matinyenya, B., Muchinga, T., Smith, L., Pandie, S., Lenders, L., Patel, V., Mayosi, B. M. & Dheda, K., Jul 11 2014, In : Scientific Reports. 4, 5658.

Research output: Contribution to journalArticle

Bacterial Load
Tuberculosis
Polymerase Chain Reaction
Lung
Bronchoalveolar Lavage Fluid
Tuberculosis
Economics
Inventions
Administrative Personnel
Routine Diagnostic Tests

High uptake of systematic HIV counseling and testing and TB symptom screening at a primary care clinic in South Africa

Van Rie, A., Clouse, K., Hanrahan, C., Selibas, K., Sanne, I., Williams, S., Kim, P. & Bassett, J., Sep 30 2014, In : PLoS One. 9, 9, e105428.

Research output: Contribution to journalArticle

counseling
South Africa
tuberculosis
Counseling
Primary Health Care

Impact of systematic HIV testing on case finding and retention in care at a primary care clinic in South Africa

Clouse, K., Hanrahan, C., Bassett, J., Fox, M. P., Sanne, I. & Van Rie, A., Dec 1 2014, In : Tropical Medicine and International Health. 19, 12, p. 1411-1419 9 p.

Research output: Contribution to journalArticle

South Africa
Primary Health Care
Counseling
HIV
CD4 Lymphocyte Count

Urine lateral flow lipoarabinomannan assay for diagnosing active tuberculosis in adults living with HIV

Shah, M., Hanrahan, C., Wang, Z. Y., Steingart, K. R., Lawn, S. D., Denkinger, C. & Dendukuri, N., Dec 8 2014, In : Cochrane Database of Systematic Reviews. 2014, 12, CD011420.

Research output: Contribution to journalArticle

Sputum
Tuberculosis
HIV
Urine
Microscopy

Xpert MTB/RIF as a measure of sputum bacillary burden: Variation by HIV status and immunosuppression

Hanrahan, C., Theron, G., Bassett, J., Dheda, K., Scott, L., Stevens, W., Sanne, I. & Van Rie, A., Jun 1 2014, In : American Journal of Respiratory and Critical Care Medicine. 189, 11, p. 1426-1434 9 p.

Research output: Contribution to journalArticle

Sputum
Immunosuppression
HIV
CD4 Lymphocyte Count
Microscopy

Xpert MTB/RIF assay shortens airborne isolation for hospitalized patients with presumptive tuberculosis in the United States

Lippincott, C. K., Miller, M. B., Popowitch, E. B., Hanrahan, C. & Van Rie, A., Jul 15 2014, In : Clinical Infectious Diseases. 59, 2, p. 186-192 7 p.

Research output: Contribution to journalArticle

Patient Isolation
Microscopy
Tuberculosis
Infection
Sputum
2013

Correction: The impact of expanded testing for multidrug resistant tuberculosis using geontype MTBDRplus in South Africa: An observational cohort study (PLoS ONE)

Hanrahan, C., Dorman, S. E., Erasmus, L., Koornhof, H., Coetzee, G. & Golub, J. E., Jun 25 2013, In : PLoS One. 8, 6

Research output: Contribution to journalArticle

Multidrug-Resistant Tuberculosis
South Africa
cohort studies
tuberculosis
Observational Studies

Point-of-care Xpert® MTB/RIF for smear-negative tuberculosis suspects at a primary care clinic in South Africa

Van Rie, A., Page-Shipp, L., Hanrahan, C., Schnippel, K., Dansey, H., Bassett, J., Clouse, K., Scott, L., Stevens, W. & Sanne, I., Mar 1 2013, In : International Journal of Tuberculosis and Lung Disease. 17, 3, p. 368-372 5 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
South Africa
Primary Health Care
Tuberculosis
Costs and Cost Analysis

Time to Treatment and Patient Outcomes among TB Suspects Screened by a Single Point-of-Care Xpert MTB/RIF at a Primary Care Clinic in Johannesburg, South Africa

Hanrahan, C., Selibas, K., Deery, C. B., Dansey, H., Clouse, K., Bassett, J., Scott, L., Stevens, W., Sanne, I. & van Rie, A., Jun 6 2013, In : PLoS One. 8, 6, e65421.

Research output: Contribution to journalArticle

Point-of-Care Systems
South Africa
tuberculosis
Primary Health Care
Tuberculosis
2012

Candidacy for kidney transplantation of older adults

Grams, M., Kucirka, L. M., Hanrahan, C., Montgomery, R. A., Massie, A. B. & Segev, D., Jan 2012, In : Journal of the American Geriatrics Society. 60, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Kidney Transplantation
Medicare
Chronic Kidney Failure
Kidney
Calibration

The Impact of Expanded Testing for Multidrug Resistant Tuberculosis Using Geontype MTBDRplus in South Africa: An Observational Cohort Study

Hanrahan, C., Dorman, S. E., Erasmus, L., Koornhof, H., Coetzee, G. & Golub, J. E., Nov 30 2012, In : PLoS One. 7, 11, e49898.

Research output: Contribution to journalArticle

Multidrug-Resistant Tuberculosis
South Africa
cohort studies
tuberculosis
Observational Studies

Urine antigen test for diagnosis of HIV-associated tuberculosis

Hanrahan, C. & Van Rie, A., Nov 2012, In : Lancet Infectious Diseases. 12, 11, p. 826 1 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Bacterial Antigens
Pulmonary Tuberculosis
HIV Infections
Lipopolysaccharides

Verification bias in a diagnostic accuracy study of symptom screening for tuberculosis in HIV-infected pregnant women

Hanrahan, C., Westreich, D. & Van Rie, A., May 1 2012, In : Clinical Infectious Diseases. 54, 9, p. 1377-1378 2 p.

Research output: Contribution to journalArticle

Infectious Pregnancy Complications
Mass Screening
HIV Infections
Pregnant Women
Tuberculosis
2011

Identification of SQ609 as a lead compound from a library of dipiperidines

Bogatcheva, E., Hanrahan, C., Nikonenko, B., De Los Santos, G., Reddy, V., Chen, P., Barbosa, F., Einck, L., Nacy, C. & Protopopova, M., Sep 15 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 18, p. 5353-5357 5 p.

Research output: Contribution to journalArticle

Lead compounds
Mycobacterium tuberculosis
Scaffolds
Libraries
Macrophages

Progression and regression of premalignant cervical lesions in HIV-infected women from Soweto: A prospective cohort

Omar, T., Schwartz, S., Hanrahan, C., Modisenyane, T., Tshabangu, N., Golub, J. E., McIntyre, J. A., Gray, G. E., Mohapi, L. & Martinson, N. A., Jan 2 2011, In : AIDS. 25, 1, p. 87-94 8 p.

Research output: Contribution to journalArticle

HIV
Highly Active Antiretroviral Therapy
CD4 Lymphocyte Count
Squamous Intraepithelial Lesions of the Cervix
Uterine Cervical Dysplasia
2010

Body mass index and risk of tuberculosis and death

Hanrahan, C., Golub, J. E., Mohapi, L., Tshabangu, N., Modisenyane, T., Chaisson, R. E., Gray, G. E., McIntyre, J. A. & Martinson, N. A., Jun 19 2010, In : AIDS. 24, 10, p. 1501-1508 8 p.

Research output: Contribution to journalArticle

Tuberculosis
Body Mass Index
Mortality
HIV
South Africa

Discovery of dipiperidines as new antitubercular agents

Bogatcheva, E., Hanrahan, C., Chen, P., Gearhart, J., Sacksteder, K., Einck, L., Nacy, C. & Protopopova, M., Jan 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 1, p. 201-205 5 p.

Research output: Contribution to journalArticle

Antitubercular Agents
Biosynthesis
Structure-Activity Relationship
Mycobacterium tuberculosis
Cell Wall
2009

Formal policies and special informed consent are associated with higher provider utilization of CDC high-risk donor organs

Kucirka, L. M., Namuyinga, R., Hanrahan, C., Montgomery, R. A. & Segev, D., Mar 2009, In : American Journal of Transplantation. 9, 3, p. 629-635 7 p.

Research output: Contribution to journalArticle

Centers for Disease Control and Prevention (U.S.)
Informed Consent
Tissue Donors
Disclosure
Transplants

Provider utilization of high-risk donor organs and nucleic acid testing: Results of two national surveys

Kucirka, L. M., Namuyinga, R., Hanrahan, C., Montgomery, R. A. & Segev, D., May 2009, In : American Journal of Transplantation. 9, 5, p. 1197-1204 8 p.

Research output: Contribution to journalArticle

Nucleic Acids
Tissue Donors
HIV
Tissue and Organ Procurement
Odds Ratio

Viral Nucleic Acid Testing (NAT) and OPO-level disposition of high-risk donor organs

Kucirka, L. M., Alexander, C., Namuyinga, R., Hanrahan, C., Montgomery, R. A. & Segev, D., Mar 2009, In : American Journal of Transplantation. 9, 3, p. 620-628 9 p.

Research output: Contribution to journalArticle

Tissue and Organ Procurement
Nucleic Acids
Tissue Donors
Organizations
HIV
2008

The high-risk donor: Viral infections in solid organ transplantation

Singer, A. L., Kucirka, L. M., Namuyinga, R., Hanrahan, C., Subramanian, A. K. & Segev, D., Aug 2008, In : Current Opinion in Organ Transplantation. 13, 4, p. 400-404 5 p.

Research output: Contribution to journalArticle

Organ Transplantation
Virus Diseases
Nucleic Acids
Hepacivirus
Tissue Donors
2006

Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis

Bogatcheva, E., Hanrahan, C., Nikonenko, B., Samala, R., Chen, P., Gearhart, J., Barbosa, F., Einck, L., Nacy, C. A. & Protopopova, M., Jun 1 2006, In : Journal of Medicinal Chemistry. 49, 11, p. 3045-3048 4 p.

Research output: Contribution to journalArticle

Piperazines
Diamines
Mycobacterium tuberculosis
Scaffolds
Animals
2005

Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines

Protopopova, M., Hanrahan, C., Nikonenko, B., Samala, R., Chen, P., Gearhart, J., Einck, L. & Nacy, C. A., Nov 2005, In : The Journal of antimicrobial chemotherapy. 56, 5, p. 968-974 7 p.

Research output: Contribution to journalArticle

Ethylenediamines
Antitubercular Agents
Mycobacterium tuberculosis
Ethambutol
ethylenediamine