Research output per year
Research output per year
- 1 - 50 out of 54 results
Search results
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2023
Cardiac progenitors instruct second heart field fate through Wnts
Miyamoto, M., Kannan, S., Anderson, M. J., Liu, X., Suh, D., Htet, M., Li, B., Kakani, T., Murphy, S., Tampakakis, E., Lewandoski, M., Andersen, P., Uosaki, H. & Kwon, C., Jan 24 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 4, e2217687120.Research output: Contribution to journal › Article › peer-review
Open Access -
Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells
Missinato, M. A., Murphy, S., Lynott, M., Yu, M. S., Kervadec, A., Chang, Y. L., Kannan, S., Loreti, M., Lee, C., Amatya, P., Tanaka, H., Huang, C. T., Puri, P. L., Kwon, C., Adams, P. D., Qian, L., Sacco, A., Andersen, P. & Colas, A. R., Dec 2023, In: Nature communications. 14, 1, 1709.Research output: Contribution to journal › Article › peer-review
Open Access -
Human induced pluripotent stem cell line YCMi007-A generated from a dilated cardiomyopathy patient with a heterozygous dominant c.613C > T (p. Arg205Trp) variant of the TNNT2 gene
Jeon, S. B., Kim, H., Chun, K. H., Oh, J., Kwon, C., Choi, H. K., Kim, S., Kim, H. P., Kim, I. C., Yoo, J. Y., Park, S. W., Kang, S. M. & Lee, S. H., Mar 2023, In: Stem Cell Research. 67, 103048.Research output: Contribution to journal › Article › peer-review
Open Access -
Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm
Kervadec, A., Kezos, J., Ni, H., Yu, M., Marchant, J., Spiering, S., Kannan, S., Kwon, C., Andersen, P., Bodmer, R., Grandi, E., Ocorr, K. & Colas, A. R., Jul 2023, In: DMM Disease Models and Mechanisms. 16, 7, dmm049962.Research output: Contribution to journal › Article › peer-review
Open Access -
Platform-agnostic CellNet enables cross-study analysis of cell fate engineering protocols
Lo, E. K. W., Velazquez, J. J., Peng, D., Kwon, C., Ebrahimkhani, M. R. & Cahan, P., Aug 8 2023, In: Stem Cell Reports. 18, 8, p. 1721-1742 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes
Kannan, S., Miyamoto, M., Zhu, R., Lynott, M., Guo, J., Chen, E. Z., Colas, A. R., Lin, B. L. & Kwon, C., Apr 25 2023, In: Cell Reports. 42, 4, 112330.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Cross-Organ Transcriptomic Comparison Reveals Universal Factors during Maturation
Kambhampati, S., Murphy, S., Uosaki, H. & Kwon, C., Sep 1 2022, In: Journal of Computational Biology. 29, 9, p. 1031-1044 14 p.Research output: Contribution to journal › Article › peer-review
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Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment
Sun, C., Kannan, S., Choi, I. Y., Lim, H. T., Zhang, H., Chen, G. S., Zhang, N., Park, S. H., Serra, C., Iyer, S. R., Lloyd, T. E., Kwon, C., Lovering, R. M., Lim, S. B., Andersen, P., Wagner, K. R. & Lee, G., Apr 7 2022, In: Cell stem cell. 29, 4, p. 610-619.e5Research output: Contribution to journal › Article › peer-review
Open Access -
Sympathetic Neurons Regulate Cardiomyocyte Maturation in Culture
Kowalski, W. J., Garcia-Pak, I. H., Li, W., Uosaki, H., Tampakakis, E., Zou, J., Lin, Y., Patterson, K., Kwon, C. & Mukouyama, Y. S., Mar 11 2022, In: Frontiers in Cell and Developmental Biology. 10, 850645.Research output: Contribution to journal › Article › peer-review
Open Access -
Uncovering the origins and lineage markers of human heart fields
Miyamoto, M. & Kwon, C., Sep 1 2022, In: Cell stem cell. 29, 9, p. 1285-1287 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
2021
Capturing Cardiogenesis in Gastruloids
Rossi, G., Broguiere, N., Miyamoto, M., Boni, A., Guiet, R., Girgin, M., Kelly, R. G., Kwon, C. & Lutolf, M. P., Feb 4 2021, In: Cell stem cell. 28, 2, p. 230-240.e6Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy
Chelko, S. P., Keceli, G., Carpi, A., Doti, N., Agrimi, J., Asimaki, A., Beti, C. B., Miyamoto, M., Amat-Codina, N., Bedja, D., Wei, A. C., Murray, B., Tichnell, C., Kwon, C., Calkins, H., James, C. A., O'Rourke, B., Halushka, M. K., Melloni, E., Saffitz, J. E., & 6 others, Feb 17 2021, In: Science translational medicine. 13, 581, eabf0891.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Heart generation and regeneration
Tampakakis, E. & Kwon, C., Oct 2021, In: Seminars in Cell and Developmental Biology. 118, p. 92-93 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Heart neurons use clock genes to control myocyte proliferation
Tampakakis, E., Gangrade, H., Glavaris, S., Htet, M., Murphy, S., Lin, B. L., Liu, T., Saberi, A., Miyamoto, M., Kowalski, W., Mukouyama, Y. S., Lee, G., Minichiello, L. & Kwon, C., Dec 2021, In: Science Advances. 7, 49, eabh4181.Research output: Contribution to journal › Article › peer-review
Open Access -
Heart organoids and tissue models for modeling development and disease
Miyamoto, M., Nam, L., Kannan, S. & Kwon, C., Oct 2021, In: Seminars in Cell and Developmental Biology. 118, p. 119-128 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Maturing heart muscle cells: Mechanisms and transcriptomic insights
Murphy, S. A., Chen, E. Z., Tung, L., Boheler, K. R. & Kwon, C., Nov 2021, In: Seminars in Cell and Developmental Biology. 119, p. 49-60 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Mechanical stimulation enhances development of scaffold-free, 3D-printed, engineered heart tissue grafts
Lui, C., Chin, A. F., Park, S., Yeung, E., Kwon, C., Tomaselli, G., Chen, Y. & Hibino, N., May 2021, In: Journal of Tissue Engineering and Regenerative Medicine. 15, 5, p. 503-512 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Noncanonical Notch signals have opposing roles during cardiac development
Miyamoto, M., Andersen, P., Sulistio, E., Liu, X., Murphy, S., Kannan, S., Nam, L., Miyamoto, W., Tampakakis, E., Hibino, N., Uosaki, H. & Kwon, C., Nov 5 2021, In: Biochemical and Biophysical Research Communications. 577, p. 12-16 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2
Murphy, S. A., Miyamoto, M., Kervadec, A., Kannan, S., Tampakakis, E., Kambhampati, S., Lin, B. L., Paek, S., Andersen, P., Lee, D. I., Zhu, R., An, S. S., Kass, D. A., Uosaki, H., Colas, A. R. & Kwon, C., Dec 1 2021, In: Nature communications. 12, 1, 1648.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Single cell RNA-seq analysis of the flexor digitorum brevis mouse myofibers
Verma, R. X., Kannan, S., Lin, B. L., Fomchenko, K. M., Nieuwenhuis, T. O., Patil, A. H., Lukban, C., Yang, X., Fox-Talbot, K., McCall, M. N., Kwon, C., Kass, D. A., Rosenberg, A. Z. & Halushka, M. K., Dec 2021, In: Skeletal Muscle. 11, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access -
Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level
Kannan, S., Farid, M., Lin, B. L., Miyamoto, M. & Kwon, C., Sep 2021, In: PLoS computational biology. 17, 9, e1009305.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation
Chanthra, N., Abe, T., Miyamoto, M., Sekiguchi, K., Kwon, C., Hanazono, Y. & Uosaki, H., Dec 1 2020, In: Scientific reports. 10, 1, 4249.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Pluripotent stem cells are insensitive to the cytotoxicity of TNFα and IFNγ
Chen, B., Gurung, C., Guo, J., Kwon, C. & Guo, Y. L., Oct 2020, In: Reproduction. 160, 4, p. 547-560 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Regulation of cardiomyocyte maturation during critical perinatal window
Kannan, S. & Kwon, C., Jul 1 2020, In: Journal of Physiology. 598, 14, p. 2941-2956 16 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2019
In vitro generation of heart field-specific cardiac progenitor cells
Tampakakis, E., Miyamoto, M. & Kwon, C., Jul 2019, In: Journal of Visualized Experiments. 2019, 149, e59826.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Large particle fluorescence-activated cell sorting enables high-quality single-cell RNA sequencing and functional analysis of adult cardiomyocytes
Kannan, S., Miyamoto, M., Lin, B. L., Zhu, R., Murphy, S., Kass, D. A., Andersen, P. & Kwon, C., Aug 16 2019, In: Circulation research. 125, 5, p. 567-569 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access13 Scopus citations -
Neurons derived from human induced pluripotent stem cells integrate into rat brain circuits and maintain both excitatory and inhibitory synaptic activities
Yin, X., Xu, J. C., Cho, G. S., Kwon, C., Dawson, T. M. & Dawson, V. L., Jul 1 2019, In: eNeuro. 6, 4, ENEURO.0148-19.2019.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2018
Precardiac organoids form two heart fields via Bmp/Wnt signaling
Andersen, P., Tampakakis, E., Jimenez, D. V., Kannan, S., Miyamoto, M., Shin, H. K., Saberi, A., Murphy, S., Sulistio, E., Chelko, S. P. & Kwon, C., Dec 1 2018, In: Nature communications. 9, 1, 3140.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification
Sadahiro, T., Isomi, M., Muraoka, N., Kojima, H., Haginiwa, S., Kurotsu, S., Tamura, F., Tani, H., Tohyama, S., Fujita, J., Miyoshi, H., Kawamura, Y., Goshima, N., Iwasaki, Y. W., Murano, K., Saito, K., Oda, M., Andersen, P., Kwon, C., Uosaki, H., & 3 others, Sep 6 2018, In: Cell stem cell. 23, 3, p. 382-395.e5Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
β1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance
Gibbs, B. C., Shenje, L., Andersen, P., Miyamoto, M. & Kwon, C., Jun 2 2018, In: Biochemical and Biophysical Research Communications. 500, 2, p. 256-260 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2017
Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy
Cho, G. S., Lee, D. I., Tampakakis, E., Murphy, S., Andersen, P., Uosaki, H., Chelko, S., Chakir, K., Hong, I., Seo, K., Chen, H. S. V., Chen, X., Basso, C., Houser, S. R., Tomaselli, G. F., O'Rourke, B., Judge, D. P., Kass, D. A. & Kwon, C., Jan 10 2017, In: Cell Reports. 18, 2, p. 571-582 12 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
Use of a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells
Cho, G. S., Tampakakis, E., Andersen, P. & Kwon, C., Oct 1 2017, In: Nature protocols. 12, 10, p. 2097-2109 13 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2016
Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons
Oh, Y., Cho, G. S., Kim, M. J., Kim, Y. J., Kwon, C. & Lee, G., Jul 1 2016, In: Cell stem cell. 19, 1, p. 95-106 12 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Sall1 transiently marks undifferentiated heart precursors and regulates their fate
Morita, Y., Andersen, P., Hotta, A., Tsukahara, Y., Sasagawa, N., Hayashida, N., Koga, C., Nishikawa, M., Saga, Y., Evans, S. M., Koshiba-Takeuchi, K., Nishinakamura, R., Yoshida, Y., Kwon, C. & Takeuchi, J. K., Mar 1 2016, In: Journal of Molecular and Cellular Cardiology. 92, p. 158-162 5 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2015
Coins of the realm in atrioventricular junction development
Kwon, C. & Tomaselli, G. F., 2015, In: Circulation research. 116, 3, p. 386-388 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access2 Scopus citations -
Ex vivo culture of pharyngeal arches to study heart and muscle progenitors and their niche
Andersen, P. & Kwon, C., Jul 20 2015, In: Journal of Visualized Experiments. 2015, 101, p. 1-4 4 p., e52876.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
Lee, D. I., Zhu, G., Sasaki, T., Cho, G. S., Hamdani, N., Holewinski, R., Jo, S. H., Danner, T., Zhang, M., Rainer, P. P., Bedja, D., Kirk, J. A., Ranek, M. J., Dostmann, W. R., Kwon, C., Margulies, K. B., Van Eyk, J. E., Paulus, W. J., Takimoto, E. & Kass, D. A., Mar 26 2015, In: Nature. 519, 7544, p. 472-476 5 p.Research output: Contribution to journal › Article › peer-review
Open Access165 Scopus citations -
Transcriptional Landscape of Cardiomyocyte Maturation
Uosaki, H., Cahan, P., Lee, D. I., Wang, S., Miyamoto, M., Fernandez, L., Kass, D. A. & Kwon, C., Nov 24 2015, In: Cell Reports. 13, 8, p. 1705-1716 12 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
2014
Mutations in Alström protein impair terminal differentiation of cardiomyocytes
Shenje, L. T., Andersen, P., Halushka, M. K., Lui, C., Fernandez, L., Collin, G. B., Amat-Alarcon, N., Meschino, W., Cutz, E., Chang, K., Yonescu, R., Batista, D. A. S., Chen, Y., Chelko, S., Crosson, J. E., Scheel, J., Vricella, L., Craig, B. D., Marosy, B. A., Mohr, D. W., & 8 others, Mar 4 2014, In: Nature communications. 5, 3416.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Precardiac deletion of numb and numblike reveals renewal of cardiac progenitors
Shenje, L. T., Andersen, P., Uosaki, H., Fernandez, L., Rainer, P. P., Cho, G. S., Lee, D. I., Zhong, W., Harvey, R. P., Kass, D. A. & Kwon, C., Apr 24 2014, In: eLife. 2014, 3, e02164.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Regenerative medicine for the heart: Perspectives on stem-cell therapy
Cho, G. S., Fernandez, L. & Kwon, C., Nov 10 2014, In: Antioxidants and Redox Signaling. 21, 14, p. 2018-2031 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access23 Scopus citations -
2013
Fibronectin mediates mesendodermal cell fate decisions
Cheng, P., Andersen, P., Hassel, D., Kaynak, B. L., Limphong, P., Juergensen, L., Kwon, C. & Srivastava, D., Jun 15 2013, In: Development (Cambridge). 140, 12, p. 2587-2596 10 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells
Uosaki, H., Magadum, A., Seo, K., Fukushima, H., Takeuchi, A., Nakagawa, Y., Moyes, K. W., Narazaki, G., Kuwahara, K., Laflamme, M., Matsuoka, S., Nakatsuji, N., Nakao, K., Kwon, C., Kass, D. A., Engel, F. B. & Yamashita, J. K., Dec 2013, In: Circulation: Cardiovascular Genetics. 6, 6, p. 624-633 10 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2012
Direct Contact with Endoderm-Like Cells Efficiently Induces Cardiac Progenitors from Mouse and Human Pluripotent Stem Cells
Uosaki, H., Andersen, P., Shenje, L. T., Fernandez, L., Christiansen, S. L. & Kwon, C., Oct 2 2012, In: PloS one. 7, 10, e46413.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Non-canonical Notch signaling: Emerging role and mechanism
Andersen, P., Uosaki, H., Shenje, L. T. & Kwon, C., May 2012, In: Trends in Cell Biology. 22, 5, p. 257-265 9 p.Research output: Contribution to journal › Review article › peer-review
138 Scopus citations -
2011
A Genome-Wide Screen Reveals a Role for microRNA-1 in Modulating Cardiac Cell Polarity
King, I. N., Qian, L., Liang, J., Huang, Y., Shieh, J. T. C., Kwon, C. & Srivastava, D., Apr 19 2011, In: Developmental Cell. 20, 4, p. 497-510 14 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Epigenetic factors and cardiac development
Van Weerd, J. H., Koshiba-Takeuchi, K., Kwon, C. & Takeuchi, J. K., Jul 15 2011, In: Cardiovascular research. 91, 2, p. 203-211 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access54 Scopus citations -
Notch post-translationally regulates β-catenin protein in stem and progenitor cells
Kwon, C., Cheng, P., King, I. N., Andersen, P., Shenje, L., Nigam, V. & Srivastava, D., Oct 2011, In: Nature cell biology. 13, 10, p. 1244-1251 8 p.Research output: Contribution to journal › Article › peer-review
181 Scopus citations -
2009
A regulatory pathway involving Notch1/β-catenin/Isl1 determines cardiac progenitor cell fate
Kwon, C., Qian, L., Cheng, P., Nigam, V., Arnold, J. & Srivastava, D., 2009, In: Nature cell biology. 11, 8, p. 951-957 7 p.Research output: Contribution to journal › Article › peer-review
Open Access161 Scopus citations -
Signaling Pathways Involved in Cardiogenesis
Srivastava, D. & Kwon, C., Jan 1 2009, Handbook of Cell Signaling, Second Edition. Elsevier, Vol. 3. p. 2601-2609 9 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations