Research output per year
Research output per year
- 24 results
Search results
-
2022
Imaging and analysis for simultaneous tracking of fluorescent biosensors in barcoded cells
Chi, W. Y., Au, G., Liang, J., Chen, C. C., Huang, C. H. & Yang, J. M., Sep 16 2022, In: STAR Protocols. 3, 3, 101611.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Deciphering cell signaling networks with massively multiplexed biosensor barcoding
Yang, J. M., Chi, W. Y., Liang, J., Takayanagi, S., Iglesias, P. A. & Huang, C. H., Dec 9 2021, In: Cell. 184, 25, p. 6193-6206.e14Research output: Contribution to journal › Article › peer-review
Open Access -
Development of dna vaccine targeting e6 and e7 proteins of human papillomavirus 16 (Hpv16) and hpv18 for immunotherapy in combination with recombinant vaccinia boost and pd-1 antibody
Peng, S., Ferrall, L., Gaillard, S., Wang, C., Chi, W. Y., Huang, C. H., Roden, R. B. S., Wu, T. C., Chang, Y. N. & Hung, C. F., Jan 1 2021, In: mBio. 12, 1, p. 1-19 19 p., e03224-20.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2020
An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells
Zhan, H., Bhattacharya, S., Cai, H., Iglesias, P. A., Huang, C. H. & Devreotes, P. N., Sep 14 2020, In: Developmental Cell. 54, 5, p. 608-623.e5Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2019
Erratum: Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation (Nature communications (2018) 9 1 (4673))
Yang, J. M., Bhattacharya, S., West-Foyle, H., Hung, C. F., Wu, T. C., Iglesias, P. A. & Huang, C. H., Jan 15 2019, In: Nature communications. 10, 1, p. 319 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Erratum to: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation (Nature Communications, (2018), 9, 1, (4673), 10.1038/s41467-018-07150-9)
Yang, J. M., Bhattacharya, S., West-Foyle, H., Hung, C. F., Wu, T. C., Iglesias, P. A. & Huang, C. H., Dec 1 2019, In: Nature communications. 10, 1, 319.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
2018
Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway
Yu, Y., Suryo Rahmanto, Y., Lee, M. H., Wu, P. H., Phillip, J. M., Huang, C. H., Vitolo, M. I., Gaillard, S., Martin, S. S., Wirtz, D., Shih, I. M. & Wang, T. L., Jul 12 2018, In: Oncogene. 37, 28, p. 3778-3789 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation
Yang, J. M., Bhattacharya, S., West-Foyle, H., Hung, C. F., Wu, T. C., Iglesias, P. A. & Huang, C. H., Dec 1 2018, In: Nature communications. 9, 1, 4673.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2017
NKCC1 Regulates Migration Ability of Glioblastoma Cells by Modulation of Actin Dynamics and Interacting with Cofilin
Schiapparelli, P., Guerrero-Cazares, H., Magaña-Maldonado, R., Hamilla, S. M., Ganaha, S., Goulin Lippi Fernandes, E., Huang, C. H., Aranda-Espinoza, H., Devreotes, P. & Quinones-Hinojosa, A., Jul 2017, In: EBioMedicine. 21, p. 94-103 10 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2016
Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration
Hoeller, O., Toettcher, J. E., Cai, H., Sun, Y., Huang, C. H., Freyre, M., Zhao, M., Devreotes, P. N. & Weiner, O. D., Feb 18 2016, In: PLoS biology. 14, 2, e1002381.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2014
Cell memory and adaptation in chemotaxis
Huang, C. H. & Iglesias, P. A., Oct 28 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. 15287-15288 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations -
Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis
Tang, M., Wang, M., Shi, C., Iglesias, P. A., Devreotes, P. N. & Huang, C. H., 2014, In: Nature communications. 5, 5175.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2013
An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration
Huang, C. H., Tang, M., Shi, C., Iglesias, P. A. & Devreotes, P. N., Nov 2013, In: Nature cell biology. 15, 11, p. 1307-1316 10 p.Research output: Contribution to journal › Article › peer-review
111 Scopus citations -
Interaction of Motility, Directional Sensing, and Polarity Modules Recreates the Behaviors of Chemotaxing Cells
Shi, C., Huang, C. H., Devreotes, P. N. & Iglesias, P. A., Jul 2013, In: PLoS computational biology. 9, 7, e1003122.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
2011
Analysis of chemotaxis in dictyostelium
Cai, H., Huang, C. H., Devreotes, P. N. & Iijima, M., 2011, Integrin and Cell Adhesion Molecules: Methods and Protocols. Shimaoka, M. & Shimaoka, M. (eds.). p. 451-468 18 p. (Methods in Molecular Biology; vol. 757).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access21 Scopus citations -
2010
Binding of nitrogen-containing bisphosphonstes (N-BPs) to the Trypanosoma cruzi fernesyl diphosphate synthase homodimer
Huang, C. H., Gabelli, S. B., Oldfield, E. & Mario Amzel, L., 2010, In: Proteins: Structure, Function and Bioinformatics. 78, 4, p. 888-899 12 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Cells navigate with a local-excitation, global-inhibition-biased excitable network
Xiong, Y., Huang, C. H., Iglesias, P. A. & Devreotes, P. N., Oct 5 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 40, p. 17079-17086 8 p.Research output: Contribution to journal › Article › peer-review
Open Access164 Scopus citations -
Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity
Swaney, K. F., Huang, C. H. & Devreotes, P. N., Jun 9 2010, In: Annual Review of Biophysics. 39, 1, p. 265-289 25 p.Research output: Contribution to journal › Review article › peer-review
Open Access339 Scopus citations -
Structural effects of oncogenic PI3Kα mutations
Gabelli, S. B., Huang, C. H., Mandelker, D., Schmidt-Kittler, O., Vogelstein, B. & Amzel, L. M., 2010, In: Current topics in microbiology and immunology. 347, 1, p. 43-53 11 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2009
A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane
Mandelker, D., Gabelli, S. B., Schmidt-Kittler, O., Zhu, J., Cheong, I., Huang, C. H., Kinzler, K. W., Vogelstein, B. & Amzel, L. M., Oct 6 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 40, p. 16996-17001 6 p.Research output: Contribution to journal › Article › peer-review
Open Access201 Scopus citations -
2008
Insights into the oncogenic effects of PIK3CA mutations from the structure of p110α/p85α
Huang, C. H., Mandelker, D., Gabelli, S. B. & Amzel, L. M., May 1 2008, In: Cell Cycle. 7, 9, p. 1151-1156 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access68 Scopus citations -
Structural comparisons of class I phosphoinositide 3-kinases
Amzel, L. M., Huang, C. H., Mandelker, D., Lengauer, C., Gabelli, S. B. & Vogelstein, B., Sep 2008, In: Nature Reviews Cancer. 8, 9, p. 665-669 5 p.Research output: Contribution to journal › Review article › peer-review
74 Scopus citations -
2007
The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations
Huang, C. H., Mandelker, D., Schmidt-Kittler, O., Samuels, Y., Velculescu, V. E., Kinzler, K. W., Vogelstein, B., Gabelli, S. B. & Amzel, L. M., Dec 14 2007, In: Science. 318, 5857, p. 1744-1748 5 p.Research output: Contribution to journal › Article › peer-review
405 Scopus citations -
2005
Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope
Huang, C. H., Peng, S., He, L., Tsai, Y. C., Boyd, D. A. K., Hansen, T. H., Wu, T. C. & Hung, C. F., Aug 2005, In: Gene Therapy. 12, 15, p. 1180-1186 7 p.Research output: Contribution to journal › Article › peer-review
Open Access68 Scopus citations