Chuan Hsiang Huang

Assistant Professor

20052019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2019
Open Access
Open Access
2018

Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway

Yu, Y., Suryo Rahmanto, Y., Lee, M. H., Wu, P. H., Phillip, J. M., Huang, C. H., Vitolo, M. I., Gaillard, S., Martin, S. S., Wirtz, D., Shih, I. M. & Wang, T-L., Apr 11 2018, (Accepted/In press) In : Oncogene. p. 1-12 12 p.

Research output: Contribution to journalArticle

2016

Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration

Hoeller, O., Toettcher, J. E., Cai, H., Sun, Y., Huang, C. H., Freyre, M., Zhao, M., Devreotes, P. N. & Weiner, O. D., Feb 18 2016, In : PLoS biology. 14, 2, e1002381.

Research output: Contribution to journalArticle

NKCC1 Regulates Migration Ability of Glioblastoma Cells by Modulation of Actin Dynamics and Interacting with Cofilin

Schiapparelli, P., Guerrero-Cazares, H., Magaña-Maldonado, R., Hamilla, S. M., Ganaha, S., Goulin Lippi Fernandes, E., Huang, C. H., Aranda-Espinoza, H., Devreotes, P. N. & Quinones-Hinojosa, A., 2016, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

2014

Cell memory and adaptation in chemotaxis

Huang, C. H. & Iglesias, P. A., Oct 28 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. 15287-15288 2 p.

Research output: Contribution to journalComment/debate

2013

An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration

Huang, C. H., Tang, M., Shi, C., Iglesias, P. A. & Devreotes, P. N., Nov 1 2013, In : Nature cell biology. 15, 11, p. 1307-1316 10 p.

Research output: Contribution to journalArticle

2011

Analysis of chemotaxis in dictyostelium

Cai, H., Huang, C. H., Devreotes, P. N. & Iijima, M., Oct 24 2011, Integrin and Cell Adhesion Molecules: Methods and Protocols. Shimaoka, M. & Shimaoka, M. (eds.). p. 451-468 18 p. (Methods in Molecular Biology; vol. 757).

Research output: Chapter in Book/Report/Conference proceedingChapter

2010

Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity

Swaney, K. F., Huang, C. H. & Devreotes, P. N., Jun 9 2010, In : Annual Review of Biophysics. 39, 1, p. 265-289 25 p.

Research output: Contribution to journalReview article

Structural effects of oncogenic PI3Kα mutations

Gabelli, S. B., Huang, C. H., Mandelker, D., Schmidt-Kittler, O., Vogelstein, B. & Amzel, L. M., Dec 1 2010, In : Current topics in microbiology and immunology. 347, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

2009

A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane

Mandelker, D., Gabelli, S. B., Schmidt-Kittler, O., Zhu, J., Cheong, I., Huang, C. H., Kinzler, K. W., Vogelstein, B. & Amzel, L. M., Oct 6 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 40, p. 16996-17001 6 p.

Research output: Contribution to journalArticle

2008

Insights into the oncogenic effects of PIK3CA mutations from the structure of p110α/p85α

Huang, C. H., Mandelker, D., Gabelli, S. B. & Amzel, L. M., May 1 2008, In : Cell Cycle. 7, 9, p. 1151-1156 6 p.

Research output: Contribution to journalReview article

Open Access

Structural comparisons of class I phosphoinositide 3-kinases

Amzel, L. M., Huang, C. H., Mandelker, D., Lengauer, C., Gabelli, S. B. & Vogelstein, B., Sep 1 2008, In : Nature Reviews Cancer. 8, 9, p. 665-669 5 p.

Research output: Contribution to journalReview article

2007

The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations

Huang, C. H., Mandelker, D., Schmidt-Kittler, O., Samuels, Y., Velculescu, V. E., Kinzler, K. W., Vogelstein, B., Gabelli, S. B. & Amzel, L. M., Dec 14 2007, In : Science. 318, 5857, p. 1744-1748 5 p.

Research output: Contribution to journalArticle

2005

Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope

Huang, C. H., Peng, S., He, L., Tsai, Y. C., Boyd, D. A. K., Hansen, T. H., Wu, T. C. & Hung, C. F., Aug 1 2005, In : Gene Therapy. 12, 15, p. 1180-1186 7 p.

Research output: Contribution to journalArticle