Christopher Gocke

Associate Professor

1992 …2019

Research output per year

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Research Output

The combination of FLT3 and DNA methyltransferase inhibition is synergistically cytotoxic to FLT3/ITD acute myeloid leukemia cells

Chang, E., Ganguly, S., Rajkhowa, T., Gocke, C., Levis, M. J. & Konig, H., Dec 21 2015, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Utility of BRAF mutation detection in fine-needle aspiration biopsy samples read as "suspicious for papillary thyroid carcinoma"

Jara, S. M., Bhatnagar, R., Guan, H., Gocke, C., Ali, S. Z. & Tufano, R. P., Dec 1 2015, In : Head and Neck. 37, 12, p. 1788-1793 6 p.

Research output: Contribution to journalArticle

2014

Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencing

Lin, M-T., Mosier, S. L., Thiess, M., Beierl, K. F., Debeljak, M., Tseng, L. H., Chen, G., Yegnasubramanian, S., Ho, H., Cope, L., Wheelan, S., Gocke, C. & Eshleman, J., 2014, In : American Journal of Clinical Pathology. 141, 6, p. 856-866 11 p.

Research output: Contribution to journalArticle

C-Myc immunohistochemistry in diffuse large B cell lymphoma

Gocke, C., Dec 10 2014, In : Pathology Case Reviews. 19, 5, p. 234-238 5 p.

Research output: Contribution to journalArticle

Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing

Chen, G., Mosier, S., Gocke, C., Lin, M-T. & Eshleman, J., Oct 1 2014, In : Molecular Diagnosis and Therapy. 18, 5, p. 587-593 7 p.

Research output: Contribution to journalArticle

False positives in multiplex PCR-based next-generation sequencing have unique signatures

McCall, C. M., Mosier, S., Thiess, M., Debeljak, M., Pallavajjalla, A., Beierl, K., Deak, K. L., Datto, M. B., Gocke, C., Lin, M-T. & Eshleman, J., 2014, In : Journal of Molecular Diagnostics. 16, 5, p. 541-549 9 p.

Research output: Contribution to journalArticle

Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection

Debeljak, M., Freed, D. N., Welch, J. A., Haley, L., Beierl, K., Iglehart, B. S., Pallavajjalla, A., Gocke, C., Leffell, M. S., Lin, M-T., Pevsner, J. A., Wheelan, S. & Eshleman, J., 2014, In : Journal of Molecular Diagnostics. 16, 5, p. 495-503 9 p.

Research output: Contribution to journalArticle

Microsatellite instability confounds engraftment analysis of hematopoietic stem-cell transplantation

Tseng, L. H., Tang, J. L., Haley, L., Beierl, K., Gocke, C., Eshleman, J. & Lin, M-T., 2014, In : Applied Immunohistochemistry and Molecular Morphology. 22, 6, p. 416-420 5 p.

Research output: Contribution to journalArticle

Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma

Tan, H. L., Sood, A., Rahimi, H. A., Wang, W., Gupta, N., Hicks, J., Mosier, S., Gocke, C., Epstein, J. I., Netto, G. J., Liu, W., Isaacs, W. B., Demarzo, A. M. & Lotan, T., 2014, In : Clinical Cancer Research. 20, 4, p. 890-903 14 p.

Research output: Contribution to journalArticle

Solitary plasmacytoma of the penile urethra treated with primary radiotherapy

Alcorn, S., Gocke, C., Woodard, C. A. & Tran, P. T., Oct 1 2014, In : Journal of Clinical Oncology. 32, 28, p. e95-e97

Research output: Contribution to journalArticle

The drowning heart: An ambiguous lymphoma

Miller, P. E., Gocke, C., Gocke, C., Cho, S. Y. & Houston, B. A., Sep 1 2014, In : American Journal of Medicine. 127, 9, p. 817-819 3 p.

Research output: Contribution to journalArticle

Tumor cellularity as a quality assurance measure for accurate clinical detection of braf mutations in melanoma

Dudley, J. C., Gurda, G. T., Tseng, L. H., Anderson, D. A., Chen, G., Taube, J. M., Gocke, C., Eshleman, J. & Lin, M-T., 2014, In : Molecular Diagnosis and Therapy. 18, 4, p. 409-418 10 p.

Research output: Contribution to journalArticle

Detection of minor clones with internal tandem duplication mutations of FLT3 gene in acute myeloid leukemia using delta-PCR

Beierl, K., Tseng, L. H., Beierl, R., Haley, L., Gocke, C., Eshleman, J. & Lin, M-T., Mar 2013, In : Diagnostic Molecular Pathology. 22, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Fine-needle aspiration of metastatic papillary thyroid carcinoma found in the liver

VandenBussche, C., Gocke, C. & Li, Q. K., May 2013, In : Diagnostic Cytopathology. 41, 5, p. 418-424 7 p.

Research output: Contribution to journalArticle

Liquid bead array technology in the detection of common translocations in acute and chronic leukemias

Shackelford, R. E., Jackson, K. D., Hafez, M. J. & Gocke, C., 2013, In : Methods in molecular biology (Clifton, N.J.). 999, p. 93-103 11 p.

Research output: Contribution to journalArticle

Multi-institutional retrospective cohort study of spontaneous pneumothorax

Belchis, D. A., Shekitka, K. & Gocke, C., Aug 2013, In : Pathology Research and Practice. 209, 8, p. 486-489 4 p.

Research output: Contribution to journalArticle

Software-automated counting of Ki-67 proliferation index correlates with pathologic grade and disease progression of follicular lymphomas

Samols, M. A., Smith, N. E., Gerber, J. M., Vuica-Ross, M., Gocke, C., Burns, K., Borowitz, M. J., Cornish, T. C. & Duffield, A. S., Oct 2013, In : American Journal of Clinical Pathology. 140, 4, p. 579-587 9 p.

Research output: Contribution to journalArticle

Tandem duplication PCR: An ultrasensitive assay for the detection of internal tandem duplications of the FLT3 Gene

Lin, M-T., Tseng, L. H., Beierl, K., Hsieh, A., Thiess, M., Chase, N., Stafford, A., Levis, M. J., Eshleman, J. & Gocke, C., Sep 2013, In : Diagnostic Molecular Pathology. 22, 3, p. 149-155 7 p.

Research output: Contribution to journalArticle

2012

A unique, histopathologic lesion in a subset of patients with spontaneous pneumothorax

Belchis, D. A., Shekitka, K. & Gocke, C., Dec 2012, In : Archives of Pathology and Laboratory Medicine. 136, 12, p. 1522-1527 6 p.

Research output: Contribution to journalArticle

A virtual pyrogram generator to resolve complex pyrosequencing results

Chen, G., Olson, M. T., O'Neill, A., Norris, A., Beierl, K., Harada, S., Debeljak, M., Rivera-Roman, K., Finley, S., Stafford, A., Gocke, C., Lin, M-T. & Eshleman, J., Mar 2012, In : Journal of Molecular Diagnostics. 14, 2, p. 149-159 11 p.

Research output: Contribution to journalArticle

Clinical and pathologic features of secondary acute promyelocytic leukemia

Duffield, A. S., Aoki, J., Levis, M. J., Cowan, K., Gocke, C., Burns, K., Borowitz, M. J. & Vuica-Ross, M., Mar 2012, In : American Journal of Clinical Pathology. 137, 3, p. 395-402 8 p.

Research output: Contribution to journalArticle

Flow cytometric findings in hemophagocytic lymphohistiocytosis

McCall, C. M., Mudali, S., Arceci, R. J., Small, D., Fuller, S., Gocke, C., Vuica-Ross, M., Burns, K., Borowitz, M. J. & Duffield, A. S., May 2012, In : American Journal of Clinical Pathology. 137, 5, p. 786-794 9 p.

Research output: Contribution to journalArticle

Flow cytometry of lesional skin enhances the evaluation of cutaneous B-cell lymphomas

Wu, J. M., Vonderheid, E., Gocke, C., Moresi, J. M., Liegeois, N. & Borowitz, M. J., Oct 2012, In : Journal of Cutaneous Pathology. 39, 10, p. 918-928 11 p.

Research output: Contribution to journalArticle

Molecular diagnostics of lymphomas

Rivera-Roman, K. & Gocke, C., Dec 7 2012, Principles of Molecular Diagnostics and Personalized Cancer Medicine. Wolters Kluwer Health Adis (ESP), p. 465-476 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia

Karp, J., Vener, T. I., Raponi, M., Ritchie, E. K., Smith, B. D., Gore, S. D., Morris, L. E., Feldman, E. J., Greer, J. M., Malek, S., Carraway, H. E., Ironside, V., Galkin, S., Levis, M. J., McDevitt, M. A., Roboz, G. R., Gocke, C., Derecho, C., Palma, J., Wang, Y. & 3 others, Kaufmann, S. H., Wright, J. J. & Garret-Mayer, E., Jan 5 2012, In : Blood. 119, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

Phase 2 study of rituximab-ABVD in classical Hodgkin lymphoma

Kasamon, Y. L., Jacene, H. A., Gocke, C., Swinnen, L., Gladstone, D., Perkins, B., Link, B. K., Popplewell, L. L., Habermann, T. M., Herman, J. M., Matsui, W. H., Jones, R. J. & Ambinder, R. F., May 3 2012, In : Blood. 119, 18, p. 4129-4132 4 p.

Research output: Contribution to journalArticle

Risk-based classification of leukemia by cytogenetic and multiplex molecular methods: Results from a multicenter validation study

Gocke, C., Mason, J., Brusca, L., Laosinchai-Wolf, W., Higgs, C., Newell, H., Masters, A., Friar, L., Karp, J., Griffiths, M., Wei, Q. & Labourier, E., Jul 2012, In : Blood Cancer Journal. 2, 7, e78.

Research output: Contribution to journalArticle

Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITDAML

Sexauer, A., Perl, A., Yang, X., Borowitz, M. J., Gocke, C., Rajkhowa, T., Thiede, C., Frattini, M., Nybakken, G. E., Pratz, K., Karp, J., Smith, B. D. & Levis, M. J., Nov 15 2012, In : Blood. 120, 20, p. 4205-4214 10 p.

Research output: Contribution to journalArticle

The importance of IGHV mutational status in del(11q) and del(17p) chronic lymphocytic leukemia

Gladstone, D., Blackford, A., Cho, E., Swinnen, L., Kasamon, Y., Gocke, C., Griffin, C. A., Bolanos Meade, F. J. & Jones, R. J., Apr 2012, In : Clinical Lymphoma, Myeloma and Leukemia. 12, 2, p. 132-137 6 p.

Research output: Contribution to journalArticle

2011

Analysis of hematopoietic stem cell transplant engraftment: Use of loss or gain of microsatellite alleles to identify residual hematopoietic malignancy

Lin, M-T., Tseng, L. H., Beierl, K., Harada, S., Hafez, M. J., Eshleman, J. & Gocke, C., Dec 2011, In : Diagnostic Molecular Pathology. 20, 4, p. 194-202 9 p.

Research output: Contribution to journalArticle

Characterization of chronic myeloid leukemia stem cells.

Gerber, J. M., Qin, L., Kowalski, J., Smith, B. D., Griffin, C. A., Vala, M. S., Collector, M. I., Perkins, B., Zahurak, M., Matsui, W., Gocke, C., Sharkis, S. J., Levitsky, H. I. & Jones, R. J., Jan 2011, In : American Journal of Hematology. 86, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Clonal immunoglobulin DNA in the plasma of patients with AIDS lymphoma

Wagner-Johnston, N., Gellert, L., Gocke, C., Lemas, M. V., Lee, J., Martínez-Maza, O. & Ambinder, R. F., May 5 2011, In : Blood. 117, 18, p. 4860-4862 3 p.

Research output: Contribution to journalArticle

Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: Peripheral oligoclonal expansion of regulatory T cells

Kanakry, C. G., Hess, A. D., Gocke, C., Thoburn, C., Kos, F., Meyer, C., Briel, J., Luznik, L., Smith, B. D., Levitsky, H. & Karp, J., Jan 13 2011, In : Blood. 117, 2, p. 608-617 10 p.

Research output: Contribution to journalArticle

Evolution of a trophoblastic tumor from an endometrioid carcinoma-A morphological and molecular analysis

Olson, M. T., Gocke, C., Giuntoli, R. L. & Shih, I. M., Mar 2011, In : International Journal of Gynecological Pathology. 30, 2, p. 117-120 4 p.

Research output: Contribution to journalArticle

Ex vivo graft purging and expansion of autologous blood progenitor cell products from patients with multiple myeloma

Yang, H., Robinson, S. N., Nieto, Y., Jones, R. J., Gocke, C., Lu, J., Giralt, S. A., Jones, R. B., Decker, W. K., Xing, D., Steiner, D., Champlin, R. E., McMannis, J. D., Ng, J., Thomas, M. W., Shah, N., Andersson, B. S., Parmar, S. & Shpall, E. J., Jul 15 2011, In : Cancer Research. 71, 14, p. 5040-5049 10 p.

Research output: Contribution to journalArticle

Importance of immunoglobulin heavy chain variable region mutational status in del(13q) chronic lymphocytic leukemia

Gladstone, D., Swinnen, L., Kasamon, Y., Blackford, A., Gocke, C., Griffin, C. A., Bolanos Meade, F. J. & Jones, R. J., Oct 2011, In : Leukemia and Lymphoma. 52, 10, p. 1873-1881 9 p.

Research output: Contribution to journalArticle

Large-vessel vasculitis as an early manifestation of chronic myelomonocytic leukemia

Park, J. K., Gelber, A., Zheng, G., McDevitt, M. A., Gocke, C. & Baer, A., Jul 10 2011, In : Journal of Clinical Oncology. 29, 20

Research output: Contribution to journalArticle

Lymphomatoid papulosis followed by pityriasis lichenoides: A common pathogenesis?

Vonderheid, E. C., Kadin, M. E. & Gocke, C., Dec 2011, In : American Journal of Dermatopathology. 33, 8, p. 835-840 6 p.

Research output: Contribution to journalArticle

Δ-PCR, a simple method to detect translocations and insertion/deletion mutations

Lin, M-T., Tseng, L. H., Rich, R. G., Hafez, M. J., Harada, S., Murphy, K. M., Eshleman, J. & Gocke, C., Jan 2011, In : Journal of Molecular Diagnostics. 13, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

2010

Auer rod-like inclusions in a low-grade B-cell leukemia

Hristov, A. C., Saladino, A., Nava, V. E. & Gocke, C., Aug 2010, In : Annals of Diagnostic Pathology. 14, 4, p. 292-295 4 p.

Research output: Contribution to journalArticle