Christopher Gocke

Associate Professor

1992 …2019

Research output per year

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Research Output

Article

p53 and APC mutations are detectable in the plasma and serum of patients with colorectal cancer (CRC) or adenomas

Gocke, C., Benko, F. A., Kopreski, M. S. & McGarrity, T. J., 2000, In : Annals of the New York Academy of Sciences. 906, p. 44-50 7 p.

Research output: Contribution to journalArticle

PD-L1 expression in inflammatory myofibroblastic tumors

Cottrell, T. R., Duong, A. T., Gocke, C., Xu, H., Ogurtsova, A., Taube, J. M. & Belchis, D. A., Feb 15 2018, (Accepted/In press) In : Modern Pathology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Pentostatin-induced hypereosinophilia with eosinophilic gastroenteritis

Shouval, R., Duffield, A. S., Gocke, C., Lee, L. A. & Brodsky, R. A., Aug 2010, In : Leukemia and Lymphoma. 51, 8, p. 1567-1569 3 p.

Research output: Contribution to journalArticle

Performance and clinical evaluation of a sensitive multiplex assay for the rapid detection of common NPM1 mutations

Hafez, M., Ye, F., Jackson, K., Yang, Z., Karp, J., Labourier, E. & Gocke, C., Sep 2010, In : Journal of Molecular Diagnostics. 12, 5, p. 629-635 7 p.

Research output: Contribution to journalArticle

Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers

Haley, L., Tseng, L. H., Zheng, G., Dudley, J., Anderson, D. A., Azad, N., Gocke, C., Eshleman, J. & Lin, M-T., Oct 3 2015, In : Modern Pathology. 28, 10, p. 1390-1399 10 p.

Research output: Contribution to journalArticle

Phase 2 study of rituximab-ABVD in classical Hodgkin lymphoma

Kasamon, Y. L., Jacene, H. A., Gocke, C., Swinnen, L., Gladstone, D., Perkins, B., Link, B. K., Popplewell, L. L., Habermann, T. M., Herman, J. M., Matsui, W. H., Jones, R. J. & Ambinder, R. F., May 3 2012, In : Blood. 119, 18, p. 4129-4132 4 p.

Research output: Contribution to journalArticle

Phase II study of G3139, a Bcl-2 antisense oligonucleotide, in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients

Badros, A. Z., Goloubeva, O., Rapoport, A. P., Ratterree, B., Gahres, N., Meisenberg, B., Takebe, N., Heyman, M., Zwiebel, J., Streicher, H., Gocke, C. D., Tomic, D., Flaws, J. A., Zhang, B. & Fenton, R. G., Dec 1 2005, In : Journal of Clinical Oncology. 23, 18, p. 4089-4099 11 p.

Research output: Contribution to journalArticle

Placental pathology in maternal and neonatal myeloproliferative disorders

Lentz, S. E., Coulson, C. C., Gocke, C. & Fantaskey, A. P., May 1998, In : Obstetrics and Gynecology. 91, 5 II SUPPL., p. 863 1 p.

Research output: Contribution to journalArticle

Pure red cell aplasia due to parvovirus B19 infection in solid organ transplantation

Ahsan, N., Holman, M. J., Gocke, C., Groff, J. A. & Yang, H. C., Aug 1997, In : Clinical Transplantation. 11, 4, p. 265-270 6 p.

Research output: Contribution to journalArticle

Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma

Tan, H. L., Sood, A., Rahimi, H. A., Wang, W., Gupta, N., Hicks, J., Mosier, S., Gocke, C., Epstein, J. I., Netto, G. J., Liu, W., Isaacs, W. B., Demarzo, A. M. & Lotan, T., 2014, In : Clinical Cancer Research. 20, 4, p. 890-903 14 p.

Research output: Contribution to journalArticle

Resolution of pansclerotic morphea after treatment with antithymocyte globulin.

Song, P., Gocke, C., Wigley, F. & Boin, F., Sep 2009, In : Nature Reviews Rheumatology. 5, 9, p. 513-516 4 p.

Research output: Contribution to journalArticle

Risk-based classification of leukemia by cytogenetic and multiplex molecular methods: Results from a multicenter validation study

Gocke, C., Mason, J., Brusca, L., Laosinchai-Wolf, W., Higgs, C., Newell, H., Masters, A., Friar, L., Karp, J., Griffiths, M., Wei, Q. & Labourier, E., Jul 2012, In : Blood Cancer Journal. 2, 7, e78.

Research output: Contribution to journalArticle

Serum BCL2/IGH DNA in follicular lymphoma patients: A minimal residual disease marker

Gocke, C., Kopreski, M. S., Benko, F. A., Sternas, L. & Kwak, L. W., 2000, In : Leukemia and Lymphoma. 39, 1-2, p. 165-172 8 p.

Research output: Contribution to journalArticle

Software-automated counting of Ki-67 proliferation index correlates with pathologic grade and disease progression of follicular lymphomas

Samols, M. A., Smith, N. E., Gerber, J. M., Vuica-Ross, M., Gocke, C., Burns, K., Borowitz, M. J., Cornish, T. C. & Duffield, A. S., Oct 2013, In : American Journal of Clinical Pathology. 140, 4, p. 579-587 9 p.

Research output: Contribution to journalArticle

Solitary plasmacytoma of the penile urethra treated with primary radiotherapy

Alcorn, S., Gocke, C., Woodard, C. A. & Tran, P. T., Oct 1 2014, In : Journal of Clinical Oncology. 32, 28, p. e95-e97

Research output: Contribution to journalArticle

Somatic mutation screening: Identification of individuals harboring K- ras mutations with the use of plasma DNA

Kopreski, M. S., Benko, F. A., Borys, D. J., Khan, A., McGarrity, T. J. & Gocke, C., Jun 7 2000, In : Journal of the National Cancer Institute. 92, 11, p. 918-923 6 p.

Research output: Contribution to journalArticle

Specimen identity testing using deoxyribonucleic acid analysis in clinical and surgical pathology setting

Harada, S. & Gocke, C., Jul 2010, In : Pathology Case Reviews. 15, 4, p. 116-120 5 p.

Research output: Contribution to journalArticle

Takayasu aortitis with acute dissection and hemopericardium

Tavora, F., Jeudy, J., Gocke, C. & Burke, A., Nov 2005, In : Cardiovascular Pathology. 14, 6, p. 320-323 4 p.

Research output: Contribution to journalArticle

Tandem duplication PCR: An ultrasensitive assay for the detection of internal tandem duplications of the FLT3 Gene

Lin, M-T., Tseng, L. H., Beierl, K., Hsieh, A., Thiess, M., Chase, N., Stafford, A., Levis, M. J., Eshleman, J. & Gocke, C., Sep 2013, In : Diagnostic Molecular Pathology. 22, 3, p. 149-155 7 p.

Research output: Contribution to journalArticle

Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: Therapy with sequential 1-β -D-arabinofuranosylcytosine, mitoxantrone, and bevacizumab

Karp, J., Gojo, I., Pili, R., Gocke, C., Greer, J., Guo, C., Qian, D., Morris, L., Tidwell, M., Chen, H. & Zwiebel, J., Jun 1 2004, In : Clinical Cancer Research. 10, 11, p. 3577-3585 9 p.

Research output: Contribution to journalArticle

Temperature-controlled SSCP analysis using a vertical slab gel unit

Benko, F. A., Gocke, C. & Patel, A., Feb 1996, In : American Biotechnology Laboratory. 14, 3, p. 44-46 3 p.

Research output: Contribution to journalArticle

Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITDAML

Sexauer, A., Perl, A., Yang, X., Borowitz, M. J., Gocke, C., Rajkhowa, T., Thiede, C., Frattini, M., Nybakken, G. E., Pratz, K., Karp, J., Smith, B. D. & Levis, M. J., Nov 15 2012, In : Blood. 120, 20, p. 4205-4214 10 p.

Research output: Contribution to journalArticle

Test feasibility of next-generation sequencing assays in clinical mutation detection of small biopsy and fine needle aspiration specimens

Zheng, G., Tsai, H., Tseng, L. H., Illei, P. B., Gocke, C., Eshleman, J., Netto, G. & Lin, M-T., May 1 2016, In : American Journal of Clinical Pathology. 145, 5, p. 696-702 7 p.

Research output: Contribution to journalArticle

The combination of FLT3 and DNA methyltransferase inhibition is synergistically cytotoxic to FLT3/ITD acute myeloid leukemia cells

Chang, E., Ganguly, S., Rajkhowa, T., Gocke, C., Levis, M. J. & Konig, H., Dec 21 2015, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia

Zheng, G., Chen, P., Pallavajjalla, A., Haley, L., Gondek, L., Dezern, A., Ling, H., De Marchi, F., Lin, M-T. & Gocke, C., Jan 1 2019, (Accepted/In press) In : American journal of hematology.

Research output: Contribution to journalArticle

The drowning heart: An ambiguous lymphoma

Miller, P. E., Gocke, C., Gocke, C., Cho, S. Y. & Houston, B. A., Sep 1 2014, In : American Journal of Medicine. 127, 9, p. 817-819 3 p.

Research output: Contribution to journalArticle

The evolution of earned, transparent, and quantifiable faculty salary compensation: The Johns Hopkins pathology experience

Burns, K., Borowitz, M. J., Carroll, K. C., Gocke, C., Hooper, J., Amukele, T. K., Tobian, A. A., Valentine, A., Kahl, R., Rodas-Eral, V., Boitnott, J. K., Jackson, J. B., Sanfilippo, F. & Hruban, R. H., Jan 1 2018, In : Academic Pathology. 5

Research output: Contribution to journalArticle

The human homologue of the Aspergillus nuclear migration gene nudC is preferentially expressed in dividing cells and ciliated epithelia

Gocke, C., Osmani, S. A. & Miller, B. A., 2000, In : Histochemistry and Cell Biology. 114, 4, p. 293-301 9 p.

Research output: Contribution to journalArticle

The importance of IGHV mutational status in del(11q) and del(17p) chronic lymphocytic leukemia

Gladstone, D., Blackford, A., Cho, E., Swinnen, L., Kasamon, Y., Gocke, C., Griffin, C. A., Bolanos Meade, F. J. & Jones, R. J., Apr 2012, In : Clinical Lymphoma, Myeloma and Leukemia. 12, 2, p. 132-137 6 p.

Research output: Contribution to journalArticle

The nuclear migration gene nudC and human hematopoiesis

Gocke, C., Reaman, G. H., Stine, C., Zhang, M. Y., Osmani, S. A. & Miller, B. A., 2000, In : Leukemia and Lymphoma. 39, 5-6, p. 447-454 8 p.

Research output: Contribution to journalArticle

Transmission of mitochondrial DNA heteroplasmy in normal pedigrees

Gocke, C., Benko, F. A. & Rogan, P. K., 1998, In : Human Genetics. 102, 2, p. 182-186 5 p.

Research output: Contribution to journalArticle

Treatment and outcomes of post-transplant lymphoproliferative disease: A single institution study

Buadi, F. K., Heyman, M. R., Gocke, C. D., Rapoport, A. P., Hakimian, R., Bartlett, S. T. & Sarkodee-Adoo, C., Mar 1 2007, In : American journal of hematology. 82, 3, p. 208-214 7 p.

Research output: Contribution to journalArticle

True histiocytic lymphoma: A study of 12 cases based on Current definition

Kamel, O. W., Gocke, C., Kell, D. L., Cleary, M. L. & Warnke, R. A., 1995, In : Leukemia and Lymphoma. 18, 1-2, p. 81-86 6 p.

Research output: Contribution to journalArticle

Tumor cellularity as a quality assurance measure for accurate clinical detection of braf mutations in melanoma

Dudley, J. C., Gurda, G. T., Tseng, L. H., Anderson, D. A., Chen, G., Taube, J. M., Gocke, C., Eshleman, J. & Lin, M-T., 2014, In : Molecular Diagnosis and Therapy. 18, 4, p. 409-418 10 p.

Research output: Contribution to journalArticle

Tumor-infiltrating macrophages in post-transplant, relapsed classical Hodgkin lymphoma are donor-derived

Crane, G. M., Samols, M. A., Morsberger, L. A., Yonescu, R., Thiess, M. L., Batista, D., Ning, Y., Burns, K., Vuica-Ross, M., Borowitz, M. J., Gocke, C., Ambinder, R. F. & Duffield, A. S., Sep 1 2016, In : PLoS One. 11, 9, e0163559.

Research output: Contribution to journalArticle

Unusual leukemia presentations: Case 2. Granulocytic sarcoma of the colon

Tummala, M., Thomas, L., Gocke, C., Heyman, M. R. & Gojo, I., 2005, In : Journal of Clinical Oncology. 23, 24, p. 5840-5841 2 p.

Research output: Contribution to journalArticle

Utility of BRAF mutation detection in fine-needle aspiration biopsy samples read as "suspicious for papillary thyroid carcinoma"

Jara, S. M., Bhatnagar, R., Guan, H., Gocke, C., Ali, S. Z. & Tufano, R. P., Dec 1 2015, In : Head and Neck. 37, 12, p. 1788-1793 6 p.

Research output: Contribution to journalArticle

Validation Strategy for Ultrasensitive Mutation Detection

Debeljak, M., Noë, M., Riel, S. L., Haley, L. M., Norris, A. L., Anderson, D. A., Adams, E. M., Suenaga, M., Beierl, K. F., Lin, M-T., Goggins, M. S., Gocke, C. & Eshleman, J., Jul 5 2018, (Accepted/In press) In : Molecular Diagnosis and Therapy. p. 1-9 9 p.

Research output: Contribution to journalArticle

Whole-exome sequencing of metaplastic breast carcinoma indicates monoclonality with associated ductal carcinoma component

Avigdor, B. E., Beierl, K., Gocke, C., Zabransky, D. J., Cravero, K., Kyker-Snowman, K., Button, B., Chu, D., Croessmann, S., Cochran, R. L., Connolly, R., Park, B. H., Wheelan, S. & Cimino-Mathews, A. M., Aug 15 2017, In : Clinical Cancer Research. 23, 16, p. 4875-4884 10 p.

Research output: Contribution to journalArticle

Widely metastatic IDH1-mutant glioblastoma with oligodendroglial features and atypical molecular findings: A case report and review of current challenges in molecular diagnostics

Romo, C. G., Palsgrove, D. N., Sivakumar, A., Elledge, C. R., Kleinberg, L. R., Chaichana, K. L., Gocke, C., Rodriguez, F. J. & Holdhoff, M., Feb 9 2019, In : Diagnostic Pathology. 14, 1, 16.

Research output: Contribution to journalArticle

Open Access

Δ-PCR, a simple method to detect translocations and insertion/deletion mutations

Lin, M-T., Tseng, L. H., Rich, R. G., Hafez, M. J., Harada, S., Murphy, K. M., Eshleman, J. & Gocke, C., Jan 2011, In : Journal of Molecular Diagnostics. 13, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Chapter

Immunohistology of Non-Hodgkin Lymphoma

Gocke, C., Jan 2006, Diagnostic Immunohistochemistry: Second Edition. Elsevier Inc., p. 137-161 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular diagnostics of lymphomas

Rivera-Roman, K. & Gocke, C., Dec 7 2012, Principles of Molecular Diagnostics and Personalized Cancer Medicine. Wolters Kluwer Health Adis (ESP), p. 465-476 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comment/debate

Erratum to: Managing the genomic revolution in cancer diagnostics (Virchows Archiv, (2017), 471, 2, (175-194), 10.1007/s00428-017-2175-2)

Nguyen, D. & Gocke, C., Aug 1 2017, In : Virchows Archiv. 471, 2, p. 195-197 3 p.

Research output: Contribution to journalComment/debate