Christopher Gocke

Associate Professor

1992 …2019

Research output per year

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Research Output

Article

Early noninvasive detection of response to targeted therapy in non–small cell lung cancer

Phallen, J., Leal, A., Woodward, B. D., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Fiksel, J., Medina, J. E., Cristiano, S., Palsgrove, D. N., Gocke, C., Bruhm, D. C., Keshavarzian, P., Adleff, V., Weihe, E., Anagnostou, V., Scharpf, R. B., Velculescu, V. E. & Husain, H., Jan 1 2019, In : Cancer Research. 79, 6, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Open Access

Enrichment methods for mutation detection

Gocke, C. D., Benko, F. A., Kopreski, M. S. & Evans, D. B., Jan 1 2000, In : Annals of the New York Academy of Sciences. 906, p. 31-38 8 p.

Research output: Contribution to journalArticle

Evaluation of the Cepheid GeneXpert BCR-ABL assay

Jobbagy, Z., van Atta, R., Murphy, K. M., Eshleman, J. & Gocke, C., Apr 2007, In : Journal of Molecular Diagnostics. 9, 2, p. 220-227 8 p.

Research output: Contribution to journalArticle

Evolution of a trophoblastic tumor from an endometrioid carcinoma-A morphological and molecular analysis

Olson, M. T., Gocke, C. D., Giuntoli, R. L. & Shih, I. M., Mar 1 2011, In : International Journal of Gynecological Pathology. 30, 2, p. 117-120 4 p.

Research output: Contribution to journalArticle

Ex vivo graft purging and expansion of autologous blood progenitor cell products from patients with multiple myeloma

Yang, H., Robinson, S. N., Nieto, Y., Jones, R. J., Gocke, C. D., Lu, J., Giralt, S. A., Jones, R. B., Decker, W. K., Xing, D., Steiner, D., Champlin, R. E., McMannis, J. D., Ng, J., Thomas, M. W., Shah, N., Andersson, B. S., Parmar, S. & Shpall, E. J., Jul 15 2011, In : Cancer Research. 71, 14, p. 5040-5049 10 p.

Research output: Contribution to journalArticle

False positives in multiplex PCR-based next-generation sequencing have unique signatures

McCall, C. M., Mosier, S., Thiess, M., Debeljak, M., Pallavajjala, A., Beierl, K., Deak, K. L., Datto, M. B., Gocke, C. D., Lin, M. T. & Eshleman, J. R., Sep 2014, In : Journal of Molecular Diagnostics. 16, 5, p. 541-549 9 p.

Research output: Contribution to journalArticle

Flow cytometric findings in hemophagocytic lymphohistiocytosis

McCall, C. M., Mudali, S., Arceci, R. J., Small, D., Fuller, S., Gocke, C. D., Vuica-Ross, M., Burns, K. H., Borowitz, M. J. & Duffield, A. S., May 1 2012, In : American journal of clinical pathology. 137, 5, p. 786-794 9 p.

Research output: Contribution to journalArticle

Flow cytometry of lesional skin enhances the evaluation of cutaneous B-cell lymphomas

Wu, J. M., Vonderheid, E., Gocke, C. D., Moresi, J. M., Liegeois, N. & Borowitz, M. J., Oct 1 2012, In : Journal of Cutaneous Pathology. 39, 10, p. 918-928 11 p.

Research output: Contribution to journalArticle

Genetic profiling by single-nucleotide polymorphism-based array analysis defines three distinct subtypes of orbital meningioma

Ho, C. Y., Mosier, S., Safneck, J., Salomao, D. R., Miller, N. R., Eberhart, C. G., Gocke, C. D., Batista, D. A. S. & Rodriguez, F. J., Mar 1 2015, In : Brain Pathology. 25, 2, p. 193-201 9 p.

Research output: Contribution to journalArticle

Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection

Debeljak, M., Freed, D. N., Welch, J. A., Haley, L., Beierl, K., Iglehart, B. S., Pallavajjala, A., Gocke, C. D., Leffell, M. S., Lin, M. T., Pevsner, J., Wheelan, S. J. & Eshleman, J. R., Sep 2014, In : Journal of Molecular Diagnostics. 16, 5, p. 495-503 9 p.

Research output: Contribution to journalArticle

Haplotype Counting for Sensitive Chimerism Testing: Potential for Early Leukemia Relapse Detection

Debeljak, M., Mocci, E., Morrison, M. C., Pallavajjalla, A., Beierl, K., Amiel, M., Noë, M., Wood, L. D., Lin, M-T., Gocke, C., Klein, A., Fuchs, E. J., Jones, R. J. & Eshleman, J., May 1 2017, In : Journal of Molecular Diagnostics. 19, 3, p. 427-436 10 p.

Research output: Contribution to journalArticle

Heterogeneity of resistance mutations detectable by nextgeneration sequencing in TKI-treated lung adenocarcinoma

Belchis, D. A., Tseng, L. H., Gniadek, T., Haley, L., Lokhandwala, P., Illei, P. B., Gocke, C., Forde, P., Brahmer, J., Askin, F. B., Eshleman, J. & Lin, M-T., 2016, In : Oncotarget. 7, 29, p. 45237-45248 12 p.

Research output: Contribution to journalArticle

High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias

Morisot, S., Wayne, A. S., Bohana-Kashtan, O., Kaplan, I. M., Gocke, C. D., Hildreth, R., Stetler-Stevenson, M., Walker, R. L., Davis, S., Meltzer, P. S., Wheelan, S. J., Brown, P., Jones, R. J., Shultz, L. D. & Civin, C. I., Nov 23 2010, In : Leukemia. 24, 11, p. 1859-1866 8 p.

Research output: Contribution to journalArticle

Hodgkin lymphoma stem cells

Jones, R. J., Gocke, C., Ambinder, R. F. & Matsui, W., Oct 29 2009, In : Blood. 114, 18, p. 3971-3972 2 p.

Research output: Contribution to journalArticle

Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell lymphoma

Kasamon, Y. L., Jones, R. J., Brodsky, R. A., Fuchs, E. J., Matsui, W., Luznik, L., Powell, J. D., Blackford, A. L., Goodrich, A., Gocke, C. D., Abrams, R. A., Ambinder, R. F. & Flinn, I. W., Oct 30 2009, In : Annals of Oncology. 21, 6, p. 1203-1210 8 p.

Research output: Contribution to journalArticle

Importance of immunoglobulin heavy chain variable region mutational status in del(13q) chronic lymphocytic leukemia

Gladstone, D., Swinnen, L., Kasamon, Y., Blackford, A., Gocke, C., Griffin, C. A., Bolanos Meade, F. J. & Jones, R. J., Oct 2011, In : Leukemia and Lymphoma. 52, 10, p. 1873-1881 9 p.

Research output: Contribution to journalArticle

Improved FLT3 Internal Tandem Duplication PCR Assay Predicts Outcome after Allogeneic Transplant for Acute Myeloid Leukemia

Grunwald, M. R., Tseng, L. H., Lin, M. T., Pratz, K. W., Eshleman, J. R., Levis, M. J. & Gocke, C. D., Dec 1 2014, In : Biology of Blood and Marrow Transplantation. 20, 12, p. 1989-1995 7 p.

Research output: Contribution to journalArticle

Individualized Molecular Analyses Guide Efforts (IMAGE): A prospective study of molecular profiling of tissue and blood in metastatic triple-negative breast cancer

Parsons, H. A., Beaver, J., Cimino-Mathews, A. M., Ali, S. M., Axilbund, J., Chu, D., Connolly, R., Cochran, R. L., Croessmann, S., Clark, T. A., Gocke, C., Jeter, S. C., Kennedy, M. R., Lauring, J., Lee, J., Lipson, D., Miller, V. A., Otto, G. A., Rosner, G., Ross, J. S. & 10 others, Slater, S., Stephens, P. J., Vandenberg, D. A., Wolff, A. C., Young, L. E., Zabransky, D. J., Zhang, Z., Zorzi, J., Stearns, V. & Park, B. H., Jan 15 2017, In : Clinical Cancer Research. 23, 2, p. 379-386 8 p.

Research output: Contribution to journalArticle

K562/GM-CSF immunotherapy reduces tumor burden in chronic myeloid leukemia patients with residual disease on imatinib mesylate

Smith, B. D., Kasamon, Y. L., Kowalski, J., Gocke, C., Murphy, K., Miller, C. B., Garrett-Mayer, E., Tsai, H. L., Qin, L., Chia, C., Biedrzycki, B., Harding, T. C., Tu, G. H., Jones, R. J., Hege, K. & Levitsky, H. I., Jan 1 2010, In : Clinical Cancer Research. 16, 1, p. 338-347 10 p.

Research output: Contribution to journalArticle

KRAS oncogene mutations suggest a common histogenetic origin for pleomorphic giant cell tumor of the pancreas, osteoclastoma of the pancreas, and pancreatic duct adenocarcinoma

Gocke, C. D., Dabbs, D. J., Benko, F. A. & Silverman, J. F., Jan 1 1997, In : Human pathology. 28, 1, p. 80-83 4 p.

Research output: Contribution to journalArticle

Large cell lymphoma presenting as a flare of colitis in a patient with common variable immune deficiency

Dunnigan, M., Yfantis, H., Rapoport, A. P., Hosseinzadeh, K., Gocke, C. D. & Cross, R. K., Mar 1 2007, In : Digestive Diseases and Sciences. 52, 3, p. 830-834 5 p.

Research output: Contribution to journalArticle

Large-vessel vasculitis as an early manifestation of chronic myelomonocytic leukemia

Park, J. K., Gelber, A. C., Zheng, G., McDevitt, M. A., Gocke, C. D. & Baer, A. N., Jul 10 2011, In : Journal of Clinical Oncology. 29, 20, p. e601-e603

Research output: Contribution to journalArticle

Liquid bead array technology in the detection of common translocations in acute and chronic leukemias

Shackelford, R. E., Jackson, K. D., Hafez, M. J. & Gocke, C., 2013, In : Methods in molecular biology (Clifton, N.J.). 999, p. 93-103 11 p.

Research output: Contribution to journalArticle

Livedoid vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity (4G/4G) treated successfully with tissue plasminogen activator

Deng, A., Gocke, C., Hess, J., Heyman, M., Paltiel, M. & Gaspari, A., 2006, In : Archives of Dermatology. 142, 11, p. 1466-1469 4 p.

Research output: Contribution to journalArticle

Loss of heterozygosity and microsatellite instability at the retinoblastoma locus in osteosarcomas

Belchis, D. A., Meece, C. A., Benko, F. A., Rogan, P. K., Williams, R. A. & Gocke, C. D., Sep 1 1996, In : Diagnostic Molecular Pathology. 5, 3, p. 214-219 6 p.

Research output: Contribution to journalArticle

Loss of the mismatched human leukocyte antigen haplotype in two acute myelogenous leukemia relapses after haploidentical bone marrow transplantation with post-transplantation cyclophosphamide

McCurdy, S. R., Iglehart, B. S., Batista, D., Gocke, C., Ning, Y., Knaus, H. A., Jackson, A., Leffell, M. S., Luznik, L. & Gojo, I., Jun 17 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Lymph node metastases of melanoma: Challenges for BRAF mutation detection

Chen, G., Dudley, J., Tseng, L. H., Smith, K., Gurda, G. T., Gocke, C., Eshleman, J. & Lin, M-T., Jan 1 2015, In : Human Pathology. 46, 1, p. 113-119 7 p.

Research output: Contribution to journalArticle

Lymphocytic progenitor cell origin and clonal evolution of human B- lineage acute lymphoblastic leukemia

Davi, F., Gocke, C., Smith, S. & Sklar, J., Jul 15 1996, In : Blood. 88, 2, p. 609-621 13 p.

Research output: Contribution to journalArticle

Lymphomatoid papulosis followed by pityriasis lichenoides: A common pathogenesis?

Vonderheid, E. C., Kadin, M. E. & Gocke, C. D., Dec 1 2011, In : American Journal of Dermatopathology. 33, 8, p. 835-840 6 p.

Research output: Contribution to journalArticle

Managing the genomic revolution in cancer diagnostics

Nguyen, D. & Gocke, C., Jun 21 2017, (Accepted/In press) In : Virchows Archiv. p. 1-21 21 p.

Research output: Contribution to journalArticle

Mitochondrial DNA mutation analysis in human skin fibroblasts from fetal, young, and old donors

Gerhard, G. S., Benko, F. A., Allen, R. G., Tresini, M., Kalbach, A., Cristofalo, V. J. & Gocke, C. D., Jan 1 2002, In : Mechanisms of Ageing and Development. 123, 2-3, p. 155-166 12 p.

Research output: Contribution to journalArticle

Molecular evidence of JAK2 p.V617F mutated pure erythroid leukemia arising from polycythemia vera

Ware, A. D., Birkness, J., Duffield, A. S. & Gocke, C., Apr 2 2018, (Accepted/In press) In : Virchows Archiv. p. 1-5 5 p.

Research output: Contribution to journalArticle

Monomorphic post-transplant lymphoproliferative disorder of the tongue: Case report and review of literature

Gonzalez-Cuyar, L. F., Tavora, F., Burke, A. P., Gocke, C. D., Zimrin, A., Sauk, J. J. & Zhao, X. F., Dec 1 2007, In : Diagnostic Pathology. 2, 1, 49.

Research output: Contribution to journalArticle

Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia

Karp, J. E., Vener, T. I., Raponi, M., Ritchie, E. K., Smith, B. D., Gore, S. D., Morris, L. E., Feldman, E. J., Greer, J. M., Malek, S., Carraway, H. E., Ironside, V., Galkin, S., Levis, M. J., McDevitt, M. A., Roboz, G. R., Gocke, C. D., Derecho, C., Palma, J., Wang, Y. & 3 others, Kaufmann, S. H., Wright, J. J. & Garret-Mayer, E., Jan 5 2012, In : Blood. 119, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

Multi-institutional retrospective cohort study of spontaneous pneumothorax

Belchis, D. A., Shekitka, K. & Gocke, C. D., Aug 1 2013, In : Pathology Research and Practice. 209, 8, p. 486-489 4 p.

Research output: Contribution to journalArticle

Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites

Inoue, Y., Chua, K., McClure, R. F., Jimenez, M. C., Gocke, C. D., Badros, A. Z. & Takebe, N., Jun 2005, In : Leukemia Research. 29, 6, p. 715-718 4 p.

Research output: Contribution to journalArticle

Mutational profiling of colorectal cancers with microsatellite instability

Lin, E. I., Tseng, L. H., Gocke, C. D., Reil, S., Le, D. T., Azad, N. S. & Eshleman, J. R., Jan 1 2015, In : Oncotarget. 6, 39, p. 42334-42344 11 p.

Research output: Contribution to journalArticle

Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia

Ma, C., Gocke, C. D., Hruban, R. H. & Belchis, D. A., Feb 1 2016, In : Human pathology. 48, p. 117-121 5 p.

Research output: Contribution to journalArticle

Non-p.V600E BRAF mutations are common using a more sensitive and broad detection tool

Carter, J., Tseng, L. H., Zheng, G., Dudley, J., Illei, P., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Oct 2015, In : American journal of clinical pathology. 144, 4, p. 620-628 9 p.

Research output: Contribution to journalArticle

Oral plasmablastic lymphoma in an HIV-negative patient: A case report and review of the literature

Scheper, M. A., Nikitakis, N. G., Fernandes, R., Gocke, C., Ord, R. A. & Sauk, J. J., Aug 2005, In : Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 100, 2, p. 198-206 9 p.

Research output: Contribution to journalArticle

p53 and APC mutations are detectable in the plasma and serum of patients with colorectal cancer (CRC) or adenomas

Gocke, C. D., Benko, F. A., Kopreski, M. S. & McGarrity, T. J., Jan 1 2000, In : Annals of the New York Academy of Sciences. 906, p. 44-50 7 p.

Research output: Contribution to journalArticle

PD-L1 expression in inflammatory myofibroblastic tumors

Cottrell, T. R., Duong, A. T., Gocke, C., Xu, H., Ogurtsova, A., Taube, J. M. & Belchis, D. A., Feb 15 2018, (Accepted/In press) In : Modern Pathology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Performance and clinical evaluation of a sensitive multiplex assay for the rapid detection of common NPM1 mutations

Hafez, M., Ye, F., Jackson, K., Yang, Z., Karp, J. E., Labourier, E. & Gocke, C. D., Sep 2010, In : Journal of Molecular Diagnostics. 12, 5, p. 629-635 7 p.

Research output: Contribution to journalArticle