Christopher Gocke

Associate Professor

1992 …2019

Research output per year

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Research Output

Article

34-Year-old woman with hypotension, respiratory failure, fever, and an abdominal mass

Lee, P. C., Gocke, C., Harris, E. D., Pillsbury, H. E., Bergin, C. J., Vosti, K. L., Melmon, K. L. & Clinkingbeard, C., 1993, In : Western Journal of Medicine. 158, 5, p. 499-505 7 p.

Research output: Contribution to journalArticle

47-Year-old woman with six-week history of lower extremity weakness and eosinophilia

Lee, P. C., Gocke, C., Harris, E. D., Anderson, M. E., Bergin, C. J., Price, J. M. & Lindsey, J. W., 1992, In : Western Journal of Medicine. 156, 5, p. 517-522 6 p.

Research output: Contribution to journalArticle

A fatal clostridium infection in an allogeneic stem cell transplant recipient [3]

Jain, M., Titanji, R., Rapoport, A. P., Wang, W., Gocke, C., Cross, A. & Akpek, G., Sep 2005, In : Bone Marrow Transplantation. 36, 5, p. 455-457 3 p.

Research output: Contribution to journalArticle

A germline ERBB3 variant is a candidate for predisposition to erythroid MDS/erythroleukemia

Braunstein, E., Li, R., Sobreira, N., Marosy, B., Hetrick, K., Doheny, K., Gocke, C., Valle, D., Brodsky, R. A. & Cheng, L., Jul 15 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis

Miller, B. A., Zhang, M. Y., Gocke, C., De Souza, C., Osmani, A. H., Lynch, C., Davies, J., Bell, L. & Osmani, S. A., Apr 1999, In : Experimental Hematology. 27, 4, p. 742-750 9 p.

Research output: Contribution to journalArticle

Alterations in the RB, p16, and cyclin D1 cell cycle control pathway in osteosarcomas

Belchis, D. A., Gocke, C. & Geradts, J., 2000, In : Pediatric Pathology and Molecular Medicine. 19, 5, p. 377-389 13 p.

Research output: Contribution to journalArticle

A molecular fraction collecting tool for the ABI 310 automated sequencer

Lin, M-T., Rich, R. G., Shipley, R. F., Hafez, M. J., Tseng, L. H., Murphy, K. M., Gocke, C. & Eshleman, J., Nov 2007, In : Journal of Molecular Diagnostics. 9, 5, p. 598-603 6 p.

Research output: Contribution to journalArticle

Analysis of hematopoietic stem cell transplant engraftment: Use of loss or gain of microsatellite alleles to identify residual hematopoietic malignancy

Lin, M-T., Tseng, L. H., Beierl, K., Harada, S., Hafez, M. J., Eshleman, J. & Gocke, C., Dec 2011, In : Diagnostic Molecular Pathology. 20, 4, p. 194-202 9 p.

Research output: Contribution to journalArticle

Analytical Validation of Androgen Receptor Splice Variant 7 Detection in a Clinical Laboratory Improvement Amendments (CLIA) Laboratory Setting

Lokhandwala, P., Riel, S. L., Haley, L., Lu, C., Chen, Y., Silberstein, J., Zhu, Y., Zheng, G., Lin, M-T., Gocke, C., Partin, A. W., Antonarakis, E., Luo, J. & Eshleman, J., Jan 1 2017, In : Journal of Molecular Diagnostics. 19, 1, p. 115-125 11 p.

Research output: Contribution to journalArticle

A next-generation sequencing-based assay for minimal residual disease assessment in AML patients with FLT3-ITD mutations

Levis, M. J., Perl, A. E., Altman, J. K., Gocke, C., Bahceci, E., Hill, J., Liu, C., Xie, Z., Carson, A. R., McClain, V., Stenzel, T. T. & Miller, J. E., Apr 24 2018, In : Blood advances. 2, 8, p. 825-831 7 p.

Research output: Contribution to journalArticle

A Novel Tandem Duplication Assay to Detect Minimal Residual Disease in FLT3/ITD AML

Lin, M-T., Tseng, L. H., Dudley, J. C., Riel, S., Tsai, H., Zheng, G., Pratz, K., Levis, M. J. & Gocke, C., Dec 1 2015, In : Molecular Diagnosis and Therapy. 19, 6, p. 409-417 9 p.

Research output: Contribution to journalArticle

A phase i trial of the VEGF receptor tyrosine kinase inhibitor pazopanib in combination with the MEK inhibitor trametinib in advanced solid tumors and differentiated thyroid cancers

Kurzrock, R., Ball, D. W., Zahurak, M. L., Nelkin, B. D., Subbiah, V., Ahmed, S., O'Connor, A., Karunsena, E., Parkinson, R., Bishop, J. A., Ha, Y., Sharma, R., Gocke, C., Zinner, R., Rudek-Renaut, M., Sherman, S. I. & Azad, N., Sep 15 2019, In : Clinical Cancer Research. 25, 18, p. 5475-5484 10 p.

Research output: Contribution to journalArticle

A polycythemia vera JAK2 mutation masquerading as a duodenal cancer mutation

Lee, J., Axilbund, J., Dalton, W., Laheru, D., Watkins, S., Chu, D., Cravero, K., Button, B., Kyker-Snowman, K., Waters, I., Gocke, C., Lauring, J. & Park, B. H., Dec 1 2016, In : JNCCN Journal of the National Comprehensive Cancer Network. 14, 12, p. 1495-1498 4 p.

Research output: Contribution to journalArticle

Application of traditional clinical pathology quality control techniques to molecular pathology

Liang, S. L., Lin, M-T., Hafez, M. J., Gocke, C., Murphy, K. M., Sokoll, L. J. & Eshleman, J., Mar 2008, In : Journal of Molecular Diagnostics. 10, 2, p. 142-146 5 p.

Research output: Contribution to journalArticle

A rare e14a3 (b3a3) BCR-ABL fusion transcript in chronic myeloid leukemia: Diagnostic challenges in clinical laboratory practice

Jinawath, N., Norris-Kirby, A., Smith, B. D., Gocke, C., Batista, D., Griffin, C. A. & Murphy, K. M., Jul 2009, In : Journal of Molecular Diagnostics. 11, 4, p. 359-363 5 p.

Research output: Contribution to journalArticle

Association of acute myeloid leukemia’s most immature phenotype with risk groups and outcomes

Gerber, J. M., Zeidner, J. F., Morse, S., Blackford, A. L., Perkins, B., Yanagisawa, B., Zhang, H., Morsberger, L., Karp, J., Ning, Y., Gocke, C., Rosner, G., Smith, B. D. & Jones, R. J., Apr 30 2016, In : Haematologica. 101, 5, p. 607-616 10 p.

Research output: Contribution to journalArticle

Auer rod-like inclusions in a low-grade B-cell leukemia

Hristov, A. C., Saladino, A., Nava, V. E. & Gocke, C., Aug 2010, In : Annals of Diagnostic Pathology. 14, 4, p. 292-295 4 p.

Research output: Contribution to journalArticle

A unique, histopathologic lesion in a subset of patients with spontaneous pneumothorax

Belchis, D. A., Shekitka, K. & Gocke, C., Dec 2012, In : Archives of Pathology and Laboratory Medicine. 136, 12, p. 1522-1527 6 p.

Research output: Contribution to journalArticle

A virtual pyrogram generator to resolve complex pyrosequencing results

Chen, G., Olson, M. T., O'Neill, A., Norris, A., Beierl, K., Harada, S., Debeljak, M., Rivera-Roman, K., Finley, S., Stafford, A., Gocke, C., Lin, M-T. & Eshleman, J., Mar 2012, In : Journal of Molecular Diagnostics. 14, 2, p. 149-159 11 p.

Research output: Contribution to journalArticle

Bone Marrow Findings in Patients With Acute Promyelocytic Leukemia Treated With Arsenic Trioxide

Miller, K. P., Venkataraman, G., Gocke, C., Batista, D., Borowitz, M. J., Burns, K., Pratz, K. & Duffield, A. S., Oct 7 2019, In : American journal of clinical pathology. 152, 5, p. 675-685 11 p.

Research output: Contribution to journalArticle

Challenges posed to pathologists in the detection of KRAS mutations in colorectal cancers

Dudley, J., Tseng, L. H., Rooper, L., Harris, M., Haley, L., Chen, G., Gocke, C., Eshleman, J. & Lin, M-T., Feb 1 2015, In : Archives of Pathology and Laboratory Medicine. 139, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

Change in IgHV Mutational Status of CLL Suggests Origin From Multiple Clones

Osman, A., Gocke, C. & Gladstone, D., Feb 1 2017, In : Clinical Lymphoma, Myeloma and Leukemia. 17, 2, p. 97-99 3 p.

Research output: Contribution to journalArticle

Characterization of chronic myeloid leukemia stem cells.

Gerber, J. M., Qin, L., Kowalski, J., Smith, B. D., Griffin, C. A., Vala, M. S., Collector, M. I., Perkins, B., Zahurak, M., Matsui, W., Gocke, C., Sharkis, S. J., Levitsky, H. I. & Jones, R. J., Jan 2011, In : American Journal of Hematology. 86, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Circulating clonotypic B cells in classic Hodgkin lymphoma

Jones, R. J., Gocke, C., Kasamon, Y. L., Miller, C. B., Perkins, B., Barber, J. P., Vala, M. S., Gerber, J. M., Gellert, L. L., Siedner, M., Lemas, M. V., Brennan, S., Ambinder, R. F. & Matsui, W., 2009, In : Blood. 113, 23, p. 5920-5926 7 p.

Research output: Contribution to journalArticle

Circulating RNA as a tumor marker: Detection of 5T4 mRNA in breast and lung cancer patient serum

Kopreski, M. S., Benko, F. A. & Gocke, C., 2001, In : Annals of the New York Academy of Sciences. 945, p. 172-178 7 p.

Research output: Contribution to journalArticle

Circulating tumor DNA as a clinical test in resected pancreatic cancer

Groot, V. P., Mosier, S., Javed, A. A., Teinor, J. A., Gemenetzis, G., Ding, D., Haley, L. M., Yu, J., Burkhart, R. A., Hasanain, A., Debeljak, M., Kamiyama, H., Narang, A., Laheru, D. A., Zheng, L., Lin, M. T., Gocke, C. D., Fishman, E. K., Hruban, R. H., Goggins, M. G. & 7 others, Quintus Molenaar, I., Cameron, J. L., Weiss, M. J., Velculescu, V. E., He, J., Wolfgang, C. L. & Eshleman, J. R., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4973-4984 12 p.

Research output: Contribution to journalArticle

Clinical and pathologic features of secondary acute promyelocytic leukemia

Duffield, A. S., Aoki, J., Levis, M. J., Cowan, K., Gocke, C., Burns, K., Borowitz, M. J. & Vuica-Ross, M., Mar 2012, In : American Journal of Clinical Pathology. 137, 3, p. 395-402 8 p.

Research output: Contribution to journalArticle

Clinical detection and categorization of uncommon and concomitant mutations involving BRAF

Zheng, G., Tseng, L. H., Chen, G., Haley, L., Illei, P. B., Gocke, C., Eshleman, J. & Lin, M-T., Oct 24 2015, In : BMC Cancer. 15, 1, 779.

Research output: Contribution to journalArticle

Open Access

Clinical mutational profiling of 1006 lung cancers by next generation sequencing

Illei, P. B., Belchis, D. A., Tseng, L. H., Nguyen, D., De Marchi, F., Haley, L., Riel, S., Beierl, K., Zheng, G., Brahmer, J., Askin, F. B., Gocke, C., Eshleman, J., Forde, P. & Lin, M-T., Jan 1 2017, In : Oncotarget. 8, 57, p. 96684-96696 13 p.

Research output: Contribution to journalArticle

Clinical validation of coexisting activating mutations within EGFR, mitogen-activated protein kinase, and phosphatidylinositol 3-kinase pathways in lung cancers

De Marchi, F., Haley, L., Fryer, H., Ibrahim, J., Beierl, K., Zheng, G., Gocke, C., Eshleman, J., Belchis, D. A., Illei, P. B. & Lin, M-T., Feb 1 2019, In : Archives of Pathology and Laboratory Medicine. 143, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

Clinical validation of coexisting driver mutations in colorectal cancers

Zheng, G., Tseng, L. H., Haley, L., Ibrahim, J., Bynum, J., Xian, R., Gocke, C., Eshleman, J. & Lin, M-T., Apr 1 2019, In : Human pathology. 86, p. 12-20 9 p.

Research output: Contribution to journalArticle

Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencing

Lin, M-T., Mosier, S. L., Thiess, M., Beierl, K. F., Debeljak, M., Tseng, L. H., Chen, G., Yegnasubramanian, S., Ho, H., Cope, L., Wheelan, S., Gocke, C. & Eshleman, J., 2014, In : American Journal of Clinical Pathology. 141, 6, p. 856-866 11 p.

Research output: Contribution to journalArticle

Clonal immunoglobulin DNA in the plasma of patients with AIDS lymphoma

Wagner-Johnston, N., Gellert, L., Gocke, C., Lemas, M. V., Lee, J., Martínez-Maza, O. & Ambinder, R. F., May 5 2011, In : Blood. 117, 18, p. 4860-4862 3 p.

Research output: Contribution to journalArticle

C-Myc immunohistochemistry in diffuse large B cell lymphoma

Gocke, C., Dec 10 2014, In : Pathology Case Reviews. 19, 5, p. 234-238 5 p.

Research output: Contribution to journalArticle

Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: Diagnostic and clinical implications

Tsiatis, A. C., Norris-Kirby, A., Rich, R. G., Hafez, M. J., Gocke, C., Eshleman, J. & Murphy, K. M., Jul 1 2010, In : Journal of Molecular Diagnostics. 12, 4, p. 425-432 8 p.

Research output: Contribution to journalArticle

Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma

Bendandi, M., Gocke, C., Kobrin, C., Benko, F. A., Sternas, L. A., Pennington, R., Watson, T. M., Reynolds, C. W., Gause, B. L., Duffey, P. L., Jaffe, E. S., Creekmore, S. P., Longo, D. L. & Kwak, L. W., Oct 1999, In : Nature Medicine. 5, 10, p. 1171-1177 7 p.

Research output: Contribution to journalArticle

Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing

Chen, G., Mosier, S., Gocke, C., Lin, M-T. & Eshleman, J., Oct 1 2014, In : Molecular Diagnosis and Therapy. 18, 5, p. 587-593 7 p.

Research output: Contribution to journalArticle

Detection of chromosomal translocation in hematologic malignancies by a novel DNA-based Looped Ligation Assay (LOLA)

Harada, S., Sizzle, E., Lin, M-T. & Gocke, C., Jul 1 2017, In : Clinical Chemistry. 63, 7, p. 1278-1287 10 p.

Research output: Contribution to journalArticle

Detection of minor clones with internal tandem duplication mutations of FLT3 gene in acute myeloid leukemia using delta-PCR

Beierl, K., Tseng, L. H., Beierl, R., Haley, L., Gocke, C., Eshleman, J. & Lin, M-T., Mar 2013, In : Diagnostic Molecular Pathology. 22, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer

Kopreski, M. S., Benko, F. A., Kwee, C., Leitzel, K. E., Eskander, E., Lipton, A. & Gocke, C., 1997, In : British Journal of Cancer. 76, 10, p. 1293-1299 7 p.

Research output: Contribution to journalArticle

Detection of tumor messenger RNA in the serum of patients with malignant melanoma

Kopreski, M. S., Benko, F. A., Kwak, L. W. & Gocke, C., Aug 1999, In : Clinical Cancer Research. 5, 8, p. 1961-1965 5 p.

Research output: Contribution to journalArticle

Development of an integrated assay for detection of BCR-ABL RNA

Winn-Deen, E. S., Helton, B., Van Atta, R., Wong, W., Peralta, J., Wang, J., Tsongalis, G. J., Belloni, D., Chan, D., Eshleman, J., Gocke, C., Jobbagy, Z., Beppu, L. & Radich, J. P., Sep 2007, In : Clinical Chemistry. 53, 9, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility? A report of the association for molecular pathology

Gold, B., Cankovic, M., Furtado, L. V., Meier, F. & Gocke, C., May 1 2015, In : Journal of Molecular Diagnostics. 17, 3, p. 209-224 16 p.

Research output: Contribution to journalArticle

Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation

Gondek, L., Zheng, G., Ghiaur, G., Dezern, A., Matsui, W., Yegnasubramanian, S., Lin, M-T., Levis, M. J., Eshleman, J., Varadhan, R., Tucker, N., Jones, R. J. & Gocke, C., Mar 15 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle