Christopher Gocke

Associate Professor

1992 …2019
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Research Output 1992 2019

1992

47-Year-old woman with six-week history of lower extremity weakness and eosinophilia

Lee, P. C., Gocke, C., Harris, E. D., Anderson, M. E., Bergin, C. J., Price, J. M. & Lindsey, J. W., 1992, In : Western Journal of Medicine. 156, 5, p. 517-522 6 p.

Research output: Contribution to journalArticle

Eosinophilia
Lower Extremity
Hand
Hypesthesia
Paresthesia
1993

34-Year-old woman with hypotension, respiratory failure, fever, and an abdominal mass

Lee, P. C., Gocke, C., Harris, E. D., Pillsbury, H. E., Bergin, C. J., Vosti, K. L., Melmon, K. L. & Clinkingbeard, C., 1993, In : Western Journal of Medicine. 158, 5, p. 499-505 7 p.

Research output: Contribution to journalArticle

Adrenal Gland Neoplasms
Pheochromocytoma
Respiratory Insufficiency
Hypotension
Differential Diagnosis
1995

True histiocytic lymphoma: A study of 12 cases based on Current definition

Kamel, O. W., Gocke, C., Kell, D. L., Cleary, M. L. & Warnke, R. A., 1995, In : Leukemia and Lymphoma. 18, 1-2, p. 81-86 6 p.

Research output: Contribution to journalArticle

Histiocytic Sarcoma
Immunoglobulin Light Chain Genes
Lymph Nodes
Immunoglobulin Heavy Chain Genes
Immunophenotyping
1996

Loss of heterozygosity and microsatellite instability at the retinoblastoma locus in osteosarcomas

Belchis, D. A., Meece, C. A., Benko, F. A., Rogan, P. K., Williams, R. A. & Gocke, C., Sep 1996, In : Diagnostic Molecular Pathology. 5, 3, p. 214-219 6 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Retinoblastoma
Loss of Heterozygosity
Osteosarcoma
Microsatellite Repeats

Lymphocytic progenitor cell origin and clonal evolution of human B- lineage acute lymphoblastic leukemia

Davi, F., Gocke, C., Smith, S. & Sklar, J., Jul 15 1996, In : Blood. 88, 2, p. 609-621 13 p.

Research output: Contribution to journalArticle

Clonal Evolution
Immunoglobulin Heavy Chain Genes
Immunoglobulin Heavy Chains
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Stem Cells

Temperature-controlled SSCP analysis using a vertical slab gel unit

Benko, F. A., Gocke, C. & Patel, A., Feb 1996, In : American Biotechnology Laboratory. 14, 3, p. 44-46 3 p.

Research output: Contribution to journalArticle

Single-Stranded Conformational Polymorphism
Gels
Temperature
1997

Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer

Kopreski, M. S., Benko, F. A., Kwee, C., Leitzel, K. E., Eskander, E., Lipton, A. & Gocke, C., 1997, In : British Journal of Cancer. 76, 10, p. 1293-1299 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
DNA
Serum
Polymerase Chain Reaction
Healthy Volunteers
Giant Cell Tumors
Pancreatic Ducts
Oncogenes
Pancreas
Adenocarcinoma

Pure red cell aplasia due to parvovirus B19 infection in solid organ transplantation

Ahsan, N., Holman, M. J., Gocke, C., Groff, J. A. & Yang, H. C., Aug 1997, In : Clinical Transplantation. 11, 4, p. 265-270 6 p.

Research output: Contribution to journalArticle

Pure Red-Cell Aplasia
Parvoviridae Infections
Organ Transplantation
Intravenous Immunoglobulins
Tacrolimus
1998

Placental pathology in maternal and neonatal myeloproliferative disorders

Lentz, S. E., Coulson, C. C., Gocke, C. & Fantaskey, A. P., May 1998, In : Obstetrics and Gynecology. 91, 5 II SUPPL., p. 863 1 p.

Research output: Contribution to journalArticle

Neoplastic Pregnancy Complications
Myeloproliferative Disorders
Myeloid Leukemia
Acute Disease
Placenta

Transmission of mitochondrial DNA heteroplasmy in normal pedigrees

Gocke, C., Benko, F. A. & Rogan, P. K., 1998, In : Human Genetics. 102, 2, p. 182-186 5 p.

Research output: Contribution to journalArticle

Pedigree
Mitochondrial DNA
Intergenic DNA
Cytosine
Electron Transport Complex IV
1999

A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis

Miller, B. A., Zhang, M. Y., Gocke, C., De Souza, C., Osmani, A. H., Lynch, C., Davies, J., Bell, L. & Osmani, S. A., Apr 1999, In : Experimental Hematology. 27, 4, p. 742-750 9 p.

Research output: Contribution to journalArticle

Hematopoiesis
Aspergillus nidulans
Genes
Intercellular Signaling Peptides and Proteins
Fungi

Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma

Bendandi, M., Gocke, C., Kobrin, C., Benko, F. A., Sternas, L. A., Pennington, R., Watson, T. M., Reynolds, C. W., Gause, B. L., Duffey, P. L., Jaffe, E. S., Creekmore, S. P., Longo, D. L. & Kwak, L. W., Oct 1999, In : Nature Medicine. 5, 10, p. 1171-1177 7 p.

Research output: Contribution to journalArticle

Colony-Stimulating Factors
Granulocyte Colony-Stimulating Factor
Tumors
Monocytes
Lymphoma

Detection of tumor messenger RNA in the serum of patients with malignant melanoma

Kopreski, M. S., Benko, F. A., Kwak, L. W. & Gocke, C., Aug 1999, In : Clinical Cancer Research. 5, 8, p. 1961-1965 5 p.

Research output: Contribution to journalArticle

Melanoma
Messenger RNA
Monophenol Monooxygenase
Serum
Neoplasms
2000

Alterations in the RB, p16, and cyclin D1 cell cycle control pathway in osteosarcomas

Belchis, D. A., Gocke, C. & Geradts, J., 2000, In : Pediatric Pathology and Molecular Medicine. 19, 5, p. 377-389 13 p.

Research output: Contribution to journalArticle

Retinoblastoma
Cyclin D1
Osteosarcoma
Cell Cycle Checkpoints
Loss of Heterozygosity

Enrichment methods for mutation detection

Gocke, C., Benko, F. A., Kopreski, M. S. & Evans, D. B., 2000, In : Annals of the New York Academy of Sciences. 906, p. 31-38 8 p.

Research output: Contribution to journalArticle

Mutation

p53 and APC mutations are detectable in the plasma and serum of patients with colorectal cancer (CRC) or adenomas

Gocke, C., Benko, F. A., Kopreski, M. S. & McGarrity, T. J., 2000, In : Annals of the New York Academy of Sciences. 906, p. 44-50 7 p.

Research output: Contribution to journalArticle

Adenoma
Colorectal Neoplasms
Plasmas
Mutation
Serum

Serum BCL2/IGH DNA in follicular lymphoma patients: A minimal residual disease marker

Gocke, C., Kopreski, M. S., Benko, F. A., Sternas, L. & Kwak, L. W., 2000, In : Leukemia and Lymphoma. 39, 1-2, p. 165-172 8 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Residual Neoplasm
DNA
Serum
Transgenes

Somatic mutation screening: Identification of individuals harboring K- ras mutations with the use of plasma DNA

Kopreski, M. S., Benko, F. A., Borys, D. J., Khan, A., McGarrity, T. J. & Gocke, C., Jun 7 2000, In : Journal of the National Cancer Institute. 92, 11, p. 918-923 6 p.

Research output: Contribution to journalArticle

Mutation
DNA
ras Genes
Colorectal Neoplasms
Colonoscopy

The human homologue of the Aspergillus nuclear migration gene nudC is preferentially expressed in dividing cells and ciliated epithelia

Gocke, C., Osmani, S. A. & Miller, B. A., 2000, In : Histochemistry and Cell Biology. 114, 4, p. 293-301 9 p.

Research output: Contribution to journalArticle

Aspergillus
epithelium
genes
Epithelium
Genes

The nuclear migration gene nudC and human hematopoiesis

Gocke, C., Reaman, G. H., Stine, C., Zhang, M. Y., Osmani, S. A. & Miller, B. A., 2000, In : Leukemia and Lymphoma. 39, 5-6, p. 447-454 8 p.

Research output: Contribution to journalArticle

Hematopoiesis
Aspergillus nidulans
Leukemia, Erythroblastic, Acute
Messenger RNA
Granulocyte-Macrophage Colony-Stimulating Factor
2001

Circulating RNA as a tumor marker: Detection of 5T4 mRNA in breast and lung cancer patient serum

Kopreski, M. S., Benko, F. A. & Gocke, C., 2001, In : Annals of the New York Academy of Sciences. 945, p. 172-178 7 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Lung Neoplasms
RNA
Breast Neoplasms
Messenger RNA
2002

Mitochondrial DNA mutation analysis in human skin fibroblasts from fetal, young, and old donors

Gerhard, G. S., Benko, F. A., Allen, R. G., Tresini, M., Kalbach, A., Cristofalo, V. J. & Gocke, C., 2002, In : Mechanisms of Ageing and Development. 123, 2-3, p. 155-166 12 p.

Research output: Contribution to journalArticle

Fibroblasts
Mitochondrial DNA
Skin
Point Mutation
Tissue Donors
2004

Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: Therapy with sequential 1-β -D-arabinofuranosylcytosine, mitoxantrone, and bevacizumab

Karp, J., Gojo, I., Pili, R., Gocke, C., Greer, J., Guo, C., Qian, D., Morris, L., Tidwell, M., Chen, H. & Zwiebel, J., Jun 1 2004, In : Clinical Cancer Research. 10, 11, p. 3577-3585 9 p.

Research output: Contribution to journalArticle

Mitoxantrone
Cytarabine
Acute Myeloid Leukemia
Vascular Endothelial Growth Factor A
Therapeutics
2005

A fatal clostridium infection in an allogeneic stem cell transplant recipient [3]

Jain, M., Titanji, R., Rapoport, A. P., Wang, W., Gocke, C., Cross, A. & Akpek, G., Sep 2005, In : Bone Marrow Transplantation. 36, 5, p. 455-457 3 p.

Research output: Contribution to journalArticle

Transplantation Conditioning
Clostridium Infections
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Homologous Transplantation

Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites

Inoue, Y., Chua, K., McClure, R. F., Jimenez, M. C., Gocke, C., Badros, A. Z. & Takebe, N., Jun 2005, In : Leukemia Research. 29, 6, p. 715-718 4 p.

Research output: Contribution to journalArticle

Pleural Effusion
Multiple Myeloma
Ascites
Bone Marrow

Oral plasmablastic lymphoma in an HIV-negative patient: A case report and review of the literature

Scheper, M. A., Nikitakis, N. G., Fernandes, R., Gocke, C., Ord, R. A. & Sauk, J. J., Aug 2005, In : Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 100, 2, p. 198-206 9 p.

Research output: Contribution to journalArticle

HIV
CD45 Antigens
Desmin
Keratins
Rare Diseases

Phase II study of G3139, a Bcl-2 antisense oligonucleotide, in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients

Badros, A. Z., Goloubeva, O., Rapoport, A. P., Ratterree, B., Gahres, N., Meisenberg, B., Takebe, N., Heyman, M., Zwiebel, J., Streicher, H., Gocke, C., Tomic, D., Flaws, J. A., Zhang, B. & Fenton, R. G., 2005, In : Journal of Clinical Oncology. 23, 18, p. 4089-4099 11 p.

Research output: Contribution to journalArticle

Thalidomide
Antisense Oligonucleotides
Multiple Myeloma
Dexamethasone
oblimersen

Takayasu aortitis with acute dissection and hemopericardium

Tavora, F., Jeudy, J., Gocke, C. & Burke, A., Nov 2005, In : Cardiovascular Pathology. 14, 6, p. 320-323 4 p.

Research output: Contribution to journalArticle

Aortitis
Pericardial Effusion
Dissection
Adventitia
Aortic Diseases

Unusual leukemia presentations: Case 2. Granulocytic sarcoma of the colon

Tummala, M., Thomas, L., Gocke, C., Heyman, M. R. & Gojo, I., 2005, In : Journal of Clinical Oncology. 23, 24, p. 5840-5841 2 p.

Research output: Contribution to journalArticle

Myeloid Sarcoma
Combined Modality Therapy
Colonic Neoplasms
Colon
Leukemia
2006

Immunohistology of Non-Hodgkin Lymphoma

Gocke, C., Jan 2006, Diagnostic Immunohistochemistry: Second Edition. Elsevier Inc., p. 137-161 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Non-Hodgkin's Lymphoma

Livedoid vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity (4G/4G) treated successfully with tissue plasminogen activator

Deng, A., Gocke, C., Hess, J., Heyman, M., Paltiel, M. & Gaspari, A., 2006, In : Archives of Dermatology. 142, 11, p. 1466-1469 4 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Tissue Plasminogen Activator
Blood Vessels
Thrombosis
Replication Protein C
Molecular Diagnostic Techniques
Molecular Pathology
Hematologic Neoplasms
Genetic Predisposition to Disease
Lymphoma
2007

A molecular fraction collecting tool for the ABI 310 automated sequencer

Lin, M-T., Rich, R. G., Shipley, R. F., Hafez, M. J., Tseng, L. H., Murphy, K. M., Gocke, C. & Eshleman, J., Nov 2007, In : Journal of Molecular Diagnostics. 9, 5, p. 598-603 6 p.

Research output: Contribution to journalArticle

Polyacrylamide Gel Electrophoresis
Gels
DNA
Capillary Electrophoresis
Mutation

Development of an integrated assay for detection of BCR-ABL RNA

Winn-Deen, E. S., Helton, B., Van Atta, R., Wong, W., Peralta, J., Wang, J., Tsongalis, G. J., Belloni, D., Chan, D., Eshleman, J., Gocke, C., Jobbagy, Z., Beppu, L. & Radich, J. P., Sep 2007, In : Clinical Chemistry. 53, 9, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

Assays
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
RNA
Reverse Transcription
Polymerase Chain Reaction

Evaluation of the Cepheid GeneXpert BCR-ABL assay

Jobbagy, Z., van Atta, R., Murphy, K. M., Eshleman, J. & Gocke, C., Apr 2007, In : Journal of Molecular Diagnostics. 9, 2, p. 220-227 8 p.

Research output: Contribution to journalArticle

Reverse Transcriptase Polymerase Chain Reaction
Gene Fusion
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Genetic Translocation
Microfluidics

Large cell lymphoma presenting as a flare of colitis in a patient with common variable immune deficiency

Dunnigan, M., Yfantis, H., Rapoport, A. P., Hosseinzadeh, K., Gocke, C. & Cross, R. K., Mar 2007, In : Digestive Diseases and Sciences. 52, 3, p. 830-834 5 p.

Research output: Contribution to journalArticle

Common Variable Immunodeficiency
X Ray Computed Tomography
Colitis
Inflammatory Bowel Diseases
Colonic Neoplasms

Monomorphic post-transplant lymphoproliferative disorder of the tongue: Case report and review of literature

Gonzalez-Cuyar, L. F., Tavora, F., Burke, A. P., Gocke, C., Zimrin, A., Sauk, J. J. & Zhao, X. F., 2007, In : Diagnostic Pathology. 2, 1, 49.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
Tongue
Transplants
Immunosuppressive Agents
Mouth

Treatment and outcomes of post-transplant lymphoproliferative disease: A single institution study

Buadi, F. K., Heyman, M. R., Gocke, C., Rapoport, A. P., Hakimian, R., Bartlett, S. T. & Sarkodee-Adoo, C., Mar 2007, In : American Journal of Hematology. 82, 3, p. 208-214 7 p.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
Transplants
Drug Therapy
Survival
B-Cell Lymphoma
2008

Application of traditional clinical pathology quality control techniques to molecular pathology

Liang, S. L., Lin, M-T., Hafez, M. J., Gocke, C., Murphy, K. M., Sokoll, L. J. & Eshleman, J., Mar 2008, In : Journal of Molecular Diagnostics. 10, 2, p. 142-146 5 p.

Research output: Contribution to journalArticle

Clinical Pathology
Molecular Pathology
Quality Control
Microsatellite Repeats
Minisatellite Repeats
2009

A rare e14a3 (b3a3) BCR-ABL fusion transcript in chronic myeloid leukemia: Diagnostic challenges in clinical laboratory practice

Jinawath, N., Norris-Kirby, A., Smith, B. D., Gocke, C., Batista, D., Griffin, C. A. & Murphy, K. M., Jul 2009, In : Journal of Molecular Diagnostics. 11, 4, p. 359-363 5 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Fluorescence In Situ Hybridization
Polymerase Chain Reaction
Cytogenetic Analysis
Gene Fusion

Circulating clonotypic B cells in classic Hodgkin lymphoma

Jones, R. J., Gocke, C., Kasamon, Y. L., Miller, C. B., Perkins, B., Barber, J. P., Vala, M. S., Gerber, J. M., Gellert, L. L., Siedner, M., Lemas, M. V., Brennan, S., Ambinder, R. F. & Matsui, W., 2009, In : Blood. 113, 23, p. 5920-5926 7 p.

Research output: Contribution to journalArticle

Hodgkin Disease
B-Lymphocytes
Cells
Reed-Sternberg Cells
Cell Line

Hodgkin lymphoma stem cells

Jones, R. J., Gocke, C., Ambinder, R. F. & Matsui, W., Oct 29 2009, In : Blood. 114, 18, p. 3971-3972 2 p.

Research output: Contribution to journalArticle

Stem cells

Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell lymphoma

Kasamon, Y. L., Jones, R. J., Brodsky, R. A., Fuchs, E. J., Matsui, W., Luznik, L., Powell, J., Blackford, A. L., Goodrich, A., Gocke, C., Abrams, R. A., Ambinder, R. F. & Flinn, I. W., Oct 30 2009, In : Annals of Oncology. 21, 6, p. 1203-1210 8 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Stem Cell Transplantation
Disease-Free Survival
Autologous Transplantation
Transplants

Resolution of pansclerotic morphea after treatment with antithymocyte globulin.

Song, P., Gocke, C., Wigley, F. & Boin, F., Sep 2009, In : Nature Reviews Rheumatology. 5, 9, p. 513-516 4 p.

Research output: Contribution to journalArticle

Localized Scleroderma
Antilymphocyte Serum
Methylprednisolone
Methotrexate
Upper Extremity
2010

Auer rod-like inclusions in a low-grade B-cell leukemia

Hristov, A. C., Saladino, A., Nava, V. E. & Gocke, C., Aug 2010, In : Annals of Diagnostic Pathology. 14, 4, p. 292-295 4 p.

Research output: Contribution to journalArticle

B-Cell Leukemia
B-Cell Chronic Lymphocytic Leukemia
Needles
B-Lymphocytes
Neoplasms

Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: Diagnostic and clinical implications

Tsiatis, A. C., Norris-Kirby, A., Rich, R. G., Hafez, M. J., Gocke, C., Eshleman, J. & Murphy, K. M., Jul 1 2010, In : Journal of Molecular Diagnostics. 12, 4, p. 425-432 8 p.

Research output: Contribution to journalArticle

Freezing
Codon
Mutation
Oncogenes
Epidermal Growth Factor Receptor

High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias

Morisot, S., Wayne, A. S., Bohana-Kashtan, O., Kaplan, I. M., Gocke, C., Hildreth, R., Stetler-Stevenson, M., Walker, R. L., Davis, S., Meltzer, P. S., Wheelan, S., Brown, P. A., Jones, R. J., Shultz, L. D. & Civin, C. I., Nov 23 2010, In : Leukemia. 24, 11, p. 1859-1866 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Stem Cells
Gene Rearrangement
Transcriptome

K562/GM-CSF immunotherapy reduces tumor burden in chronic myeloid leukemia patients with residual disease on imatinib mesylate

Smith, B. D., Kasamon, Y. L., Kowalski, J., Gocke, C., Murphy, K., Miller, C. B., Garrett-Mayer, E., Tsai, H. L., Qin, L., Chia, C., Biedrzycki, B., Harding, T. C., Tu, G. H., Jones, R. J., Hege, K. & Levitsky, H. I., Jan 1 2010, In : Clinical Cancer Research. 16, 1, p. 338-347 10 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Tumor Burden
Immunotherapy
Vaccines