Christian Meyer

Instructor

19962019
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Research Output 1996 2019

2019
Desmoplastic Small Round Cell Tumor
Survival
Radiotherapy
Drug Therapy
Neoplasms
Sarcoma
Meta-Analysis
Recurrence
Drug Therapy
Survival
Open Access
Pelvis
Sarcoma
Radiotherapy
Extremities
Tumor Burden

Common Secondary Genomic Variants Associated With Advanced Epithelioid Hemangioendothelioma

Seligson, N. D., Awasthi, A., Millis, S. Z., Turpin, B. K., Meyer, C., Grand'Maison, A., Liebner, D. A., Hays, J. L. & Chen, J. L., Oct 2 2019, In : JAMA Network Open. 2, 10, p. e1912416

Research output: Contribution to journalArticle

Open Access
Epithelioid Hemangioendothelioma
p16 Genes
Sarcoma
Blood Vessels
Retrospective Studies

Team Approach: Emergencies in Patients with Skeletal Metastases

Levin, A., Alcorn, S., Neuman, B. J. & Meyer, C., Mar 1 2019, In : JBJS reviews. 7, 3, p. e8

Research output: Contribution to journalArticle

Emergencies
Neoplasm Metastasis
2018

BRCA1/2 Functional Loss Defines a Targetable Subset in Leiomyosarcoma

Seligson, N. D., Kautto, E. A., Passen, E. N., Stets, C., Toland, A. E., Millis, S. Z., Meyer, C., Hays, J. L. & Chen, J. L., Jan 1 2018, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Leiomyosarcoma
Sarcoma
Poly(ADP-ribose) Polymerases
Homologous Recombination
DNA Sequence Analysis

Extraskeletal versus Skeletal Ewing Sarcoma in the adult population: Controversies in care

Lynch, A. D., Gani, F., Meyer, C., Morris, C. D., Ahuja, N. & Johnston, F., Sep 1 2018, In : Surgical Oncology. 27, 3, p. 373-379 7 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Population
Survival
Therapeutics
Drug Therapy

Minimally Invasive Versus Open Primary Resection for Retroperitoneal Soft Tissue Sarcoma: A Propensity-Matched Study From the National Cancer Database

Gani, F., Goel, U., Blair, A. B., Singh, J., Overton, H. N., Meyer, C., Canner, J. K., Pawlik, T. M., Ahuja, N. & Johnston, F., May 31 2018, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Minimally Invasive Surgical Procedures
Sarcoma
Databases
Neoplasms
Propensity Score

Soft tissue sarcoma, version 2.2018: Clinical practice guidelines in oncology

Mehren, M. V., Randall, R. L., Benjamin, R. S., Boles, S., Bui, M. M., Ganjoo, K. N., George, S., Gonzalez, R. J., Heslin, M. J., Kane, J. M., Keedy, V., Kim, E., Koon, H., Mayerson, J., McCarter, M., McGarry, S. V., Meyer, C., Morris, Z. S., O'Donnell, R. J., Pappo, A. S. & 10 others, Paz, I. B., Petersen, I. A., Pfeifer, J. D., Riedel, R. F., Ruo, B., Schuetze, S., Tap, W. D., Wayne, J. D., Bergman, M. A. & Scavone, J. L., May 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 5, p. 536-563 28 p.

Research output: Contribution to journalReview article

Practice Guidelines
Sarcoma
Guidelines
Neck
Extremities
2017

Combined modality therapy improves overall survival for angiosarcoma

Shen, C. J., Parzuchowski, A. S., Kummerlowe, M. N., Morris, C. D., Meyer, C., Habibi, M., Frassica, D., Levin, A., Thornton, K. A. & Terezakis, S. A., Mar 28 2017, (Accepted/In press) In : Acta Oncologica. p. 1-4 4 p.

Research output: Contribution to journalArticle

Combined Modality Therapy
Hemangiosarcoma

High dose-rate intra-operative radiation therapy during high risk genitourinary surgery: Initial observations and a proposal for its study in bladder cancer

Kates, M., Chappidi, M. R., Brant, A., Milbar, N., Sopko, N. A., Meyer, C., Terezakis, S. A., Herman, J. M., Efron, J., Safar, B., Tran, P. T., Ahuja, N., Pierorazio, P. M. & Bivalacqua, T., Jan 1 2017, In : Bladder Cancer. 3, 3, p. 191-199 9 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Radiotherapy
Cystectomy
Survival
Histology

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Le, D., Uram, J., Smith, K., Wang, H., Bartlett, B. R., Aulakh, L. K., Lu, S., Kemberling, H., Wilt, C., Luber, B. S., Wong, F., Azad, N., Rucki, A. A., Laheru, D., Donehower, R. C., Zaheer, A., Fisher, G. A., Crocenzi, T. S., Lee, J. J., Greten, T. F. & 26 others, Duffy, A. G., Ciombor, K. K., Eyring, A. D., Lam, B. H., Joe, A., Kang, S. P., Holdhoff, M., Danilova, L. V., Cope, L., Meyer, C., Zhou, S., Goldberg, R. M., Armstrong, D. K., Bever, K., Nickles Fader, A. N., Taube, J. M., Housseau, F., Spetzler, D., Xiao, N., Pardoll, A. M., Papadopoulos, N., Kinzler, K. W., Eshleman, J., Vogelstein, B., Anders, R. A. & Diaz, L. A., Jul 28 2017, In : Science. 357, 6349, p. 409-413 5 p.

Research output: Contribution to journalArticle

Neoplasms
DNA Mismatch Repair
Disease-Free Survival
Turcot syndrome
Colorectal Neoplasms

Phase Ib/II study of the safety and efficacy of combination therapy with multikinase VEGF inhibitor pazopanib and MEK inhibitor trametinib in advanced soft tissue sarcoma

Subbiah, V., Meyer, C., Zinner, R., Meric-Bernstam, F., Zahurak, M. L., O'Connor, A., Roszik, J., Shaw, K., Ludwig, J. A., Kurzrock, R. & Azad, N., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4027-4034 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Sarcoma
Vascular Endothelial Growth Factor A
Safety
Disease-Free Survival

Size-based detection of sarcoma circulating tumor cells and cell clusters

Hayashi, M., Zhu, P., McCarty, G., Meyer, C., Pratilas, C., Levin, A., Morris, C. D., Albert, C. M., Jackson, K. W., Tang, C. M. & Loeb, D. M., 2017, In : Oncotarget. 8, 45, p. 78965-78977 13 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Sarcoma
Neoplasm Metastasis
Alveolar Rhabdomyosarcoma
RNA Sequence Analysis
2016

Familial GI stromal tumor with loss of heterozygosity and amplification of mutant KIT

Forde, P., Cochran, R. L., Boikos, S. A., Zabransky, D. J., Beaver, J., Meyer, C., Thornton, K. A., Montgomery, E. A., Lidor, A. O., Donehower, R. C. & Park, B. H., Jan 20 2016, In : Journal of Clinical Oncology. 34, 3, p. e13-e16

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-kit
Gastrointestinal Stromal Tumors
Gastrointestinal Neoplasms
Gene Amplification
Loss of Heterozygosity

Gastric and small intestine gastrointestinal stromal tumors: Do outcomes differ?

Giuliano, K., Nagarajan, N., Canner, J., Najafian, A., Wolfgang, C., Schneider, E., Meyer, C., O'Broin-Lennon, A. M., Johnston, F. & Ahuja, N., 2016, (Accepted/In press) In : Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Small Intestine
Stomach
Mortality
Survival Analysis

Highly personalized detection of minimal Ewing sarcoma disease burden from plasma tumor DNA

Hayashi, M., Chu, D., Meyer, C., Llosa, N., McCarty, G., Morris, C. D., Levin, A., Wolinsky, J. P., Albert, C. M., Steppan, D., Park, B. H. & Loeb, D. M., 2016, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Tumor Burden
DNA
Neoplasms
Heterografts

Long-term outcomes in treatment of retroperitoneal sarcomas: A 15 year single-institution evaluation of prognostic features

Abdelfatah, E., Guzzetta, A. A., Nagarajan, N., Wolfgang, C., Pawlik, T. M., Choti, M. A., Schulick, R., Montgomery, E. A., Meyer, C., Thornton, K., Herman, J., Terezakis, S. A., Frassica, D. & Ahuja, N., Jul 1 2016, In : Journal of Surgical Oncology. 114, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

Sarcoma
Recurrence
Radiotherapy
Survival
Liposarcoma

Soft tissue sarcoma, version 2.2016: Clinical practice guidelines in oncology

Von Mehren, M., Randall, R. L., Benjamin, R. S., Boles, S., Bui, M. M., Conrad, E. U., Ganjoo, K. N., George, S., Gonzalez, R. J., Heslin, M. J., Kane, J. M., Koon, H., Mayerson, J., McCarter, M., McGarry, S. V., Meyer, C., O'Donnell, R. J., Pappo, A. S., Paz, I. B., Petersen, I. A. & 9 others, Pfeifer, J. D., Riedel, R. F., Schuetze, S., Schupak, K. D., Schwartz, H. S., Tap, W. D., Wayne, J. D., Bergman, M. A. & Scavone, J., Jun 1 2016, In : JNCCN Journal of the National Comprehensive Cancer Network. 14, 6, p. 758-786 29 p.

Research output: Contribution to journalArticle

Practice Guidelines
Sarcoma
Aggressive Fibromatosis
Neoplasms
Gastrointestinal Stromal Tumors
2015

A leukemic presentation of alveolar rhabdomyosarcoma in a 52-year-old woman without an identifiable primary tumor

Kern, J. B., Hii, A., Kruse, M. J., Szabo, Z., Argani, P., Hibbard, M. K., Gladstone, D., Meyer, C., Zheng, R., Borowitz, M. J. & Duffield, A. S., Feb 13 2015, In : International Journal of Surgical Pathology. 23, 1, p. 75-77 3 p.

Research output: Contribution to journalArticle

Alveolar Rhabdomyosarcoma
Bone Marrow
Neoplasms
Rhabdomyosarcoma
Fluorodeoxyglucose F18

Multimodal Therapy in the Treatment of Prostate Sarcoma: The Johns Hopkins Experience

Ball, M. W., Sundi, D., Reese, A. C., Meyer, C., Terezakis, S. A., Efron, J., Schoenberg, M. P., Epstein, J. I., Ahuja, N. & Bivalacqua, T., Oct 1 2015, In : Clinical Genitourinary Cancer. 13, 5, p. 435-440 6 p.

Research output: Contribution to journalArticle

Sarcoma
Prostate
Survival
Recurrence
Therapeutics
2014

Evaluating the Role of Interdigitated Neoadjuvant Chemotherapy and Radiation in the Management of High-Grade Soft-Tissue Sarcoma: The Johns Hopkins Experience

Raval, R. R., Frassica, D., Thornton, K., Meyer, C., Ettinger, D. S., Frassica, F., Weber, K. & Terezakis, S. A., Sep 29 2014, (Accepted/In press) In : American Journal of Clinical Oncology: Cancer Clinical Trials.

Research output: Contribution to journalArticle

Sarcoma
Radiation
Drug Therapy
Disease-Free Survival
Survival

Gastrointestinal stromal tumors, version 2.2014: Featured updates to the NCCN Guidelines

Von Mehren, M., Randall, R. L., Benjamin, R. S., Boles, S., Bui, M. M., Casper, E. S., Conrad, E. U., DeLaney, T. F., Ganjoo, K. N., George, S., Gonzalez, R. J., Heslin, M. J., Kane, J. M., Mayerson, J., McGarry, S. V., Meyer, C., O'Donnell, R. J., Pappo, A. S., Paz, I. B., Pfeifer, J. D. & 8 others, Riedel, R. F., Schuetze, S., Schupak, K. D., Schwartz, H. S., Van Tine, B. A., Wayne, J. D., Bergman, M. A. & Sundar, H., Jun 1 2014, In : JNCCN Journal of the National Comprehensive Cancer Network. 12, 6, p. 853-862 10 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Sarcoma
Guidelines
Platelet-Derived Growth Factor Receptors
Disease Progression

Soft tissue sarcoma, version 2.2014: Featured updates to the NCCN guidelines

Von Mehren, M., Lor Randall, R., Benjamin, R. S., Boles, S., Bui, M. M., Casper, E. S., Conrad, E. U., DeLaney, T. F., Ganjoo, K. N., George, S., Gonzalez, R. J., Heslin, M. J., Kane, J. M., Mayerson, J., McGarry, S. V., Meyer, C., O'Donnell, R. J., Pappo, A. S., Paz, I. B., Pfeifer, J. D. & 8 others, Riedel, R. F., Schuetze, S., Schupak, K. D., Schwartz, H. S., Van Tine, B. A., Wayne, J. D., Bergman, M. A. & Sundar, H., 2014, In : JNCCN Journal of the National Comprehensive Cancer Network. 12, 4, p. 473-483 11 p.

Research output: Contribution to journalReview article

Sarcoma
Guidelines
Genetic Counseling
Genetic Testing
Radiotherapy
2013

A dose-finding study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcoma

Thornton, K. A., Chen, A. R., Trucco, M. M., Shah, P., Wilky, B. A., Gul, N., Carrera-Haro, M. A., Ferreira, M. F., Shafique, U., Powell, J., Meyer, C. & Loeb, D. M., Aug 15 2013, In : International Journal of Cancer. 133, 4, p. 997-1005 9 p.

Research output: Contribution to journalArticle

Sarcoma
Sirolimus
Bone and Bones
Phase II Clinical Trials
Clinical Trials, Phase I

Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas

Zeng, J., See, A. P., Phallen, J., Jackson, C. M., Belcaid, Z., Ruzevick, J., Durham, N., Meyer, C., Harris, T. J., Albesiano, E., Pradilla, G., Ford, E., Wong, J., Hammers, H. J., Mathios, D., Tyler, B. M., Brem, H., Tran, P. T., Pardoll, A. M., Drake, C. G. & 1 others, Lim, M., Jun 1 2013, In : International Journal of Radiation Oncology, Biology, Physics. 86, 2, p. 343-349 7 p.

Research output: Contribution to journalArticle

death
Glioma
mice
Radiation
Survival
Solitary Fibrous Tumors
Histology
Recurrence
England
Multivariate Analysis

Pazopanib in sarcomas: Expanding the PALETTE

Wilky, B. A., Meyer, C. & Trent, J. C., Jul 2013, In : Current Opinion in Oncology. 25, 4, p. 373-378 6 p.

Research output: Contribution to journalReview article

Sarcoma
Histology
pazopanib
Protein-Tyrosine Kinases
Disease-Free Survival
2012

Epithelioid sarcoma: One institution's experience with a rare sarcoma

Guzzetta, A. A., Montgomery, E. A., Lyu, H., Hooker, C. M., Meyer, C., Loeb, D. M., Frassica, D., Weber, K. L. & Ahuja, N., Sep 2012, In : Journal of Surgical Research. 177, 1, p. 116-122 7 p.

Research output: Contribution to journalArticle

Sarcoma
Recurrence
Survival
Neoplasms
Research Ethics Committees
Neoadjuvant Therapy
Adjuvant Chemotherapy
Stromal Cells
Sarcoma
Prostatic Neoplasms

Prostate angiosarcoma: Is there any association with previous radiation therapy?

Khaliq, W., Meyer, C., Uzoaru, I., Wolf, R. M. & Antonarakis, E., Dec 2012, In : BJU International. 110, 11 C

Research output: Contribution to journalArticle

Hemangiosarcoma
Prostate
Radiotherapy
Observational Studies
PubMed

Prostate angiosarcoma: A case report and literature review

Khaliq, W., Meyer, C., Uzoaru, I., Wolf, R. M. & Antonarakis, E., Dec 2012, In : Medical Oncology. 29, 4, p. 2901-2903 3 p.

Research output: Contribution to journalArticle

Hemangiosarcoma
Sarcoma
Prostate

Soft tissue sarcoma, version 2.2012 featured updates to the NCCN guidelines

Von Mehren, M., Benjamin, R. S., Bui, M. M., Casper, E. S., Conrad, E. U., DeLaney, T. F., Ganjoo, K. N., George, S., Gonzalez, R., Heslin, M. J., Kane, J. M., Mayerson, J., McGarry, S. V., Meyer, C., O'Donnell, R. J., Paz, I. B., Pfeifer, J. D., Pollock, R. E., Randall, R. L., Riedel, R. F. & 8 others, Schuetze, S., Schupak, K. D., Schwartz, H. S., Shankar, S., Van Tine, B. A., Wayne, J., Sundar, H. & McMillian, N. R., Aug 1 2012, In : JNCCN Journal of the National Comprehensive Cancer Network. 10, 8, p. 951-960 10 p.

Research output: Contribution to journalReview article

Aggressive Fibromatosis
Sarcoma
Gastrointestinal Stromal Tumors
Guidelines
Morbidity
2011

Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: Peripheral oligoclonal expansion of regulatory T cells

Kanakry, C. G., Hess, A. D., Gocke, C., Thoburn, C., Kos, F., Meyer, C., Briel, J., Luznik, L., Smith, B. D., Levitsky, H. & Karp, J., Jan 13 2011, In : Blood. 117, 2, p. 608-617 10 p.

Research output: Contribution to journalArticle

Chemotherapy
T-cells
Lymphocytes
Regulatory T-Lymphocytes
Acute Myeloid Leukemia
2009

Anergic T cells are metabolically anergic

Zheng, Y., Delgoffe, G. M., Meyer, C., Chan, W. & Powell, J., Nov 15 2009, In : Journal of Immunology. 183, 10, p. 6095-6101 7 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Up-Regulation
Th1 Cells
Metabolic Networks and Pathways
Leucine
2005

A 49-year-old-man with a rash

Mackowiak, P. A., Schlossberg, M. C., Meyer, C., Kauh, Y. C. & Deng, A., Sep 2005, In : American Journal of the Medical Sciences. 330, 3, p. 134-138 5 p.

Research output: Contribution to journalArticle

Exanthema

A 76-year-old man with fever and weakness

Forrest, G. N., Mackowiak, P. A., Schlossberg, M. C. & Meyer, C., Jul 2005, In : American Journal of the Medical Sciences. 330, 1, p. 32-35 4 p.

Research output: Contribution to journalArticle

Fever
2002

The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway

Chen, A. J., Zhou, G., Juan, T., Colicos, S. M., Cannon, J. P., Cabriera-Hansen, M., Meyer, C., Jurecic, R., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Fletcher, F., Tan, T. H. & Belmont, J. W., Sep 27 2002, In : Journal of Biological Chemistry. 277, 39, p. 36592-36601 10 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
JNK Mitogen-Activated Protein Kinases
Phosphoric Monoester Hydrolases
Dual-Specificity Phosphatases
Chemical activation
2001

Involvement of Hematopoietic Progenitor Kinase 1 in T Cell Receptor Signaling

Ling, P., Meyer, C., Redmond, L. P., Shui, J. W., Davis, B., Rich, R. R., Hu, M. C. T., Wange, R. L. & Tan, T. H., Jun 1 2001, In : Journal of Biological Chemistry. 276, 22, p. 18908-18914 7 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
T-cells
T-Lymphocytes
Chemical activation
Tyrosine
1999

Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)

Chen, Y. R., Meyer, C., Ahmed, B., Yao, Z. & Tan, T. H., Dec 2 1999, In : Oncogene. 18, 51, p. 7370-7377 8 p.

Research output: Contribution to journalArticle

Caspases
JNK Mitogen-Activated Protein Kinases
GRB2 Adaptor Protein
Phosphotransferases
hematopoietic progenitor kinase 1

Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated protein kinase

Hu, M. C. T., Wang, Y. P., Qiu, W. R., Mikhail, A., Meyer, C. & Tan, T. H., Sep 30 1999, In : Oncogene. 18, 40, p. 5514-5524 11 p.

Research output: Contribution to journalArticle

NF-kappa B
Protein Kinases
MAP Kinase Kinase Kinases
Phosphotransferases
Embryonic Structures

Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase

Ling, P., Yao, Z., Meyer, C., Wang, X. S., Oehrl, W., Feller, S. M. & Tan, T. H., Feb 1999, In : Molecular and Cellular Biology. 19, 2, p. 1359-1368 10 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Proteins
Phosphotransferases
hematopoietic progenitor kinase 1
Proline
1997

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

Diener, K., Wang, X. S., Chen, C., Meyer, C., Keesler, G., Zukowski, M., Tan, T. H. & Yao, Z., Sep 2 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 18, p. 9687-9692 6 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
MAP Kinase Kinase Kinase 1
MAP Kinase Kinase 4
Phosphotransferases
Protein Kinases
1996

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

Hu, M. C. T., Qiu, W. R., Wang, X., Meyer, C. & Tan, T. H., 1996, In : Genes and Development. 10, 18, p. 2251-2264 14 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Heat-Shock Proteins
Protein Kinases
Phosphotransferases
p21-Activated Kinases

Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating κB enhancer activation

Meyer, C., Wang, X., Chang, C., Templeton, D. & Tan, T. H., Apr 12 1996, In : Journal of Biological Chemistry. 271, 15, p. 8971-8976 6 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase Kinase 1
T-cells
Chemical activation
T-Lymphocytes
Transcription

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis

Chen, Y. R., Meyer, C. & Tan, T. H., Jan 12 1996, In : Journal of Biological Chemistry. 271, 2, p. 631-634 4 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 8
Chemical activation
Radiation
Apoptosis
JNK Mitogen-Activated Protein Kinases