Chhinder Sodhi

Assistant Professor

19962019
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Research Output 1996 2019

2019

Development of Intestinal Scaffolds that Mimic Native Mammalian Intestinal Tissue

Ladd, M. R., Costello, C. M., Gosztyla, C., Werts, A. D., Johnson, B., Fulton, W. B., Martin, L. Y., Redfield, E. J., Crawford, B., Panaparambil, R., Sodhi, C., March, J. C. & Hackam, D., Sep 1 2019, In : Tissue Engineering - Part A. 25, 17-18, p. 1225-1241 17 p.

Research output: Contribution to journalArticle

Scaffolds
Intestines
Tissue
Small Intestine
Short Bowel Syndrome

Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23

Chen, L., Strohmeier, V., He, Z., Deshpande, M., Catalan-Dibene, J., Durum, S. K., Moran, T. M., Kraus, T., Xiong, H., Faith, J. J., Sodhi, C., Hackam, D., Lira, S. A. & Furtado, G. C., Dec 1 2019, In : Nature communications. 10, 1, 4517.

Research output: Contribution to journalArticle

Open Access
interleukins
Interleukin-23
mice
Infant, Newborn, Diseases
enzymes
Parabiosis
Enteritis
Colitis
Mucous Membrane
Radiation

Toll Like Receptor 4 Mediated Lymphocyte Imbalance Induces Nec-Induced Lung Injury

Jia, H., Sodhi, C. P., Yamaguchi, Y., Lu, P., Ladd, M. R., Werts, A., Fulton, W. B., Wang, S., Prindle, T. & Hackam, D. J., Aug 1 2019, In : Shock (Augusta, Ga.). 52, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Lung Injury
Lymphocytes
Regulatory T-Lymphocytes
2018

Attenuation of pulmonary ACE2 activity impairs inactivation of des-arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration

Sodhi, C., Wohlford-Lenane, C., Yamaguchi, Y., Prindle, T., Fulton, W. B., Wang, S., McCray, P. B., Chappell, M., Hackam, D. & Jia, H., Jan 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 1, p. L17-L31

Research output: Contribution to journalArticle

Neutrophil Infiltration
Bradykinin
Lung
Pneumonia
CXC Chemokines

Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain

Nino, D., Zhou, Q., Yamaguchi, Y., Martin, L. Y., Wang, S., Fulton, W. B., Jia, H., Lu, P., Jr, T. P., Zhang, F., Crawford, J., Hou, Z., Mori, S., Chen, L. L., Guajardo, A., Fatemi, A., Pletnikov, M., Rangaramanujam, K., Kannan, S., Sodhi, C. & 1 others, Hackam, D., Dec 12 2018, In : Science Translational Medicine. 10, 471, eaan0237.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Brain
Toll-Like Receptor 4
Intestines
CD14 Antigens

Early detection of necrotizing enterocolitis using broadband optical spectroscopy

Goldstein, S. D., Beaulieu, R. J., Nino, D., Chun, Y., Banerjee, A., Sodhi, C. & Hackam, D., Jan 1 2018, (Accepted/In press) In : Journal of Pediatric Surgery.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Spectrum Analysis
Optical Phenomena
Halogens
Near-Infrared Spectroscopy

Fat composition in infant formula contributes to the severity of necrotising enterocolitis

Sodhi, C., Fulton, W. B., Good, M., Vurma, M., Das, T., Lai, C. S., Jia, H., Yamaguchi, Y., Lu, P., Prindle, T., Ozolek, J. A. & Hackam, D., Jan 1 2018, In : British Journal of Nutrition. 120, 6, p. 665-680 16 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Infant Formula
Fats
Lipase
Digestion

Intestinal epithelial Toll-like receptor 4 prevents metabolic syndrome by regulating interactions between microbes and intestinal epithelial cells in mice

Lu, P., Sodhi, C., Yamaguchi, Y., Jia, H., Prindle, T., Fulton, W. B., Vikram, A., Bibby, K. J., Morowitz, M. J. & Hackam, D., May 1 2018, In : Mucosal Immunology. 11, 3, p. 727-740 14 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Epithelial Cells
Peroxisome Proliferator-Activated Receptors
Microbiota
Intestinal Mucosa
Necrotizing Enterocolitis
Observation
Toll-Like Receptor 4
Therapeutics
Survival

The Development of Newborn Porcine Models for Evaluation of Tissue-Engineered Small Intestine

Ladd, M. R., Martin, L. Y., Werts, A., Costello, C., Sodhi, C., Fulton, W. B., March, J. C. & Hackam, D., Jun 1 2018, In : Tissue Engineering - Part C: Methods. 24, 6, p. 331-345 15 p.

Research output: Contribution to journalArticle

Small Intestine
Intestines
Short Bowel Syndrome
Swine
Tissue

Tissue engineering for the treatment of short bowel syndrome in children

Martin, L. Y., Ladd, M. R., Werts, A., Sodhi, C., March, J. C. & Hackam, D., Jan 1 2018, In : Pediatric Research. 83, 1-2, p. 249-257 9 p.

Research output: Contribution to journalReview article

Short Bowel Syndrome
Tissue Engineering
Intestines
Morbidity
Child Mortality

Toll-Like Receptor–Mediated Intestinal Inflammatory Imbalance in the Pathogenesis of Necrotizing Enterocolitis

Hackam, D. & Sodhi, C., Jan 1 2018, (Accepted/In press) In : CMGH.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Premature Infants
Intestinal Diseases
Gastrointestinal Diseases
2017

Enhanced Calvarial Bone Healing in CD11c-TLR4-/- and MyD88-/- Mice

Wang, D., Taylor, G. M., Gilbert, J. R., Losee, J. E., Sodhi, C., Hackam, D., Billiar, T. R. & Cooper, G. M., Apr 1 2017, In : Plastic and Reconstructive Surgery. 139, 4, p. 933e-940e

Research output: Contribution to journalArticle

Bone and Bones
Toll-Like Receptors
Inflammation
Regeneration
Myeloid Cells

TLR4 inactivation in myeloid cells accelerates bone healing of a calvarial defect model in mice

Wang, D., Gilbert, J. R., Taylor, G. M., Sodhi, C., Hackam, D., Losee, J. E., Billiar, T. R. & Cooper, G. M., Aug 1 2017, In : Plastic and Reconstructive Surgery. 140, 2, p. 296e-306e

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Myeloid Cells
Bone and Bones
Osteogenesis
Osteitis
2016

Generation of an artificial intestine for the management of short bowel syndrome

Ladd, M. R., Nino, D., March, J. C., Sodhi, C. & Hackam, D., Apr 1 2016, In : Current Opinion in Organ Transplantation. 21, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

Short Bowel Syndrome
Intestines
Stem Cells
Growth
Stem Cell Niche

Intestinal stem cell growth and differentiation on a tubular scaffold with evaluation in small and large animals

Shaffiey, S. A., Jia, H., Keane, T., Costello, C., Wasserman, D., Quidgley, M., Dziki, J., Badylak, S., Sodhi, C., March, J. C. & Hackam, D., Jan 1 2016, In : Regenerative Medicine. 11, 1, p. 45-61 17 p.

Research output: Contribution to journalArticle

Cell growth
Scaffolds (biology)
Stem cells
Scaffolds
Cell Differentiation
Necrotizing Enterocolitis
Toll-Like Receptor 4
Intestinal Mucosa
Premature Infants
Intestines

Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis

Cunningham, K. E., Vincent, G., Sodhi, C., Novak, E. A., Ranganathan, S., Egan, C. E., Stolz, D. B., Rogers, M. B., Firek, B., Morowitz, M. J., Gittes, G. K., Zuckerbraun, B. S., Hackam, D. & Mollen, K. P., May 6 2016, In : Journal of Biological Chemistry. 291, 19, p. 10184-10200 17 p.

Research output: Contribution to journalArticle

Dextran Sulfate
Peroxisome Proliferator-Activated Receptors
Colitis
Intestinal Mucosa
Chemical activation

Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice

Fritz, M., Klawonn, A. M., Nilsson, A., Singh, A. K., Zajdel, J., Wilhelms, D. B., Lazarus, M., Löfberg, A., Jaarola, M., Kugelberg, U. Ö., Billiar, T. R., Hackam, D., Sodhi, C., Breyer, M. D., Jakobsson, J., Schwaninger, M., Schütz, G., Parkitna, J. R., Saper, C. B., Blomqvist, A. & 1 others, Engblom, D., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 695-705 11 p.

Research output: Contribution to journalArticle

Synaptic Transmission
Prostaglandins
Inflammation
Dinoprostone
Corpus Striatum

Pulmonary epithelial TLR4 activation leads to lung injury in neonatal necrotizing enterocolitis

Jia, H., Sodhi, C., Yamaguchi, Y., Lu, P., Martin, L. Y., Good, M., Zhou, Q., Sung, J., Fulton, W. B., Nino, D., Prindle, T., Ozolek, J. A. & Hackam, D., Aug 1 2016, In : Journal of Immunology. 197, 3, p. 859-871 13 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Lung Injury
Lung
Premature Infants
Neutrophils

Retinoic Acid Improves Incidence and Severity of Necrotizing Enterocolitis by Lymphocyte Balance Restitution and Repopulation of LGR5+ Intestinal Stem Cells

Nino, D., Sodhi, C., Egan, C. E., Zhou, Q., Lin, J., Lu, P., Yamaguchi, Y., Jia, H., Martin, L. Y., Good, M., Fulton, W. B., Prindle, T., Ozolek, J. A. & Hackam, D., Aug 2 2016, (Accepted/In press) In : Shock.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Tretinoin
Stem Cells
Lymphocytes
Incidence

The human milk oligosaccharide 2'-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine

Good, M., Sodhi, C., Yamaguchi, Y., Jia, H., Lu, P., Fulton, W. B., Martin, L. Y., Prindle, T., Nino, D., Zhou, Q., Ma, C., Ozolek, J. A., Buck, R. H., Goehring, K. C. & Hackam, D., Oct 1 2016, In : The British journal of nutrition. 116, 7, p. 1175-1187 13 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Human Milk
Oligosaccharides
Intestines
Perfusion

Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis

Egan, C. E., Sodhi, C., Good, M., Lin, J., Jia, H., Yamaguchi, Y., Lu, P., Ma, C., Branca, M. F., Weyandt, S., Fulton, W. B., Nino, D., Prindle, T., Ozolek, J. A. & Hackam, D., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 495-508 14 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Lymphocytes
Enterocytes
Interleukin-17

Toll-like Receptor 4 Signaling on Dendritic Cells Suppresses Polymorphonuclear Leukocyte CXCR2 Expression and Trafficking via Interleukin 10 during Intra-abdominal Sepsis

Deng, M., Ma, T., Yan, Z., Zettel, K. R., Scott, M. J., Liao, H., Frank, A., Morelli, A. E., Sodhi, C., Hackam, D. & Billiar, T. R., Apr 15 2016, In : Journal of Infectious Diseases. 213, 8, p. 1280-1288 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Interleukin-10
Dendritic Cells
Sepsis
Neutrophils
2015

Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

Good, M., Sodhi, C., Egan, C. E., Afrazi, A., Jia, H., Yamaguchi, Y., Lu, P., Branca, M. F., Ma, C., Prindle, T., Mielo, S., Pompa, A., Hodzic, Z., Ozolek, J. A. & Hackam, D., Sep 19 2015, In : Mucosal Immunology. 8, 5, p. 1166-1179 14 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Human Milk
Intestinal Mucosa
Epidermal Growth Factor Receptor

Intestinal epithelial TLR-4 activation is required for the development of acute lung injury after trauma/hemorrhagic shock via the release of HMGB1 from the gut

Sodhi, C., Jia, H., Yamaguchi, Y., Lu, P., Good, M., Egan, C., Ozolek, J., Zhu, X., Billiar, T. R. & Hackam, D., May 15 2015, In : Journal of Immunology. 194, 10, p. 4931-4939 9 p.

Research output: Contribution to journalArticle

HMGB1 Protein
Hemorrhagic Shock
Acute Lung Injury
Lung Injury
Wounds and Injuries

Myocyte TLR4 enhances enteric and systemic inflammation driving late murine endotoxic ileus

Buchholz, B. M., Shapiro, R. A., Vodovotz, Y., Billiar, T. R., Sodhi, C., Hackam, D. & Bauer, A. J., May 15 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 308, 10, p. G852-G862

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Ileus
Muscle Cells
Inflammation
Interleukin-6

Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4)

Wipf, P., Eyer, B. R., Yamaguchi, Y., Zhang, F., Neal, M. D., Sodhi, C., Good, M., Branca, M., Prindle, T., Lu, P., Brodsky, J. L. & Hackam, D., Jun 3 2015, In : Tetrahedron Letters. 56, 23, p. 3097-3100 4 p., 45432.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Enterocytes
Anti-Inflammatory Agents
Galactosides
Galactosamine
2014
Necrotizing Enterocolitis
Gastrointestinal Diseases
Liver Diseases
Animal Models
Premature Birth

Evidence-based feeding strategies before and after the development of necrotizing enterocolitis

Good, M., Sodhi, C. & Hackam, D., 2014, In : Expert Review of Clinical Immunology. 10, 7, p. 875-884 10 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Human Milk
Infant, Premature, Diseases
Infant Formula
Morbidity

Genetic deletion of toll-like receptor 4 on platelets attenuates experimental pulmonary hypertension

Bauer, E. M., Chanthaphavong, R. S., Sodhi, C., Hackam, D., Billiar, T. R. & Bauer, P. M., 2014, In : Circulation Research. 114, 10, p. 1596-1600 5 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Pulmonary Hypertension
Blood Platelets
Right Ventricular Hypertrophy
Ventricular Pressure

Lactobacillus rhamnosus HN001 decreases the severity of necrotizing enterocolitis in neonatal mice and preterm piglets: Evidence in mice for a role of TLR9

Good, M., Sodhi, C., Ozolek, J. A., Buck, R. H., Goehring, K. C., Thomas, D. L., Vikram, A., Bibby, K., Morowitz, M. J., Firek, B., Lu, P. & Hackam, D., Jun 1 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 306, 11

Research output: Contribution to journalArticle

Toll-Like Receptor 9
Lactobacillus rhamnosus
Necrotizing Enterocolitis
Probiotics
DNA

Mucosa-associated bacterial diversity in necrotizing enterocolitis

Brower-Sinning, R., Zhong, D., Good, M., Firek, B., Baker, R., Sodhi, C., Hackam, D. & Morowitz, M. J., Sep 1 2014, In : PLoS One. 9, 9, e105046.

Research output: Contribution to journalArticle

enterocolitis
Necrotizing Enterocolitis
mucosa
Bacteria
Mucous Membrane

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis

Afrazi, A., Branca, M. F., Sodhi, C., Good, M., Yamaguchi, Y., Egan, C. E., Lu, P., Jia, H., Shaffiey, S., Lin, J., Ma, C., Vincent, G., Prindle, T., Weyandt, S., Neal, M. D., Ozolek, J. A., Wiersch, J., Tschurtschenthaler, M., Shiota, C., Gittes, G. K. & 5 others, Billiar, T. R., Mollen, K., Kaser, A., Blumberg, R. & Hackam, D., Apr 4 2014, In : Journal of Biological Chemistry. 289, 14, p. 9584-9599 16 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Endoplasmic Reticulum Stress
Stem cells
Stem Cells

Toll-like receptor 4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation

Ding, N., Chen, G., Hoffman, R., Loughran, P. A., Sodhi, C., Hackam, D., Billiar, T. R. & Neal, M. D., Oct 1 2014, In : Circulation: Cardiovascular Genetics. 7, 5, p. 615-624 10 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Hemorrhagic Shock
Resuscitation
Blood Platelets
Wounds and Injuries
Necrotizing Enterocolitis
Toll-Like Receptors
Inflammation
Intestinal Mucosa
Premature Infants
2013

A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis

Neal, M. D., Sodhi, C., Dyer, M., Craig, B. T., Good, M., Jia, H., Yazji, I., Afrazi, A., Richardson, W. M., Beer-Stolz, D., Ma, C., Prindle, T., Grant, Z., Branca, M. F., Ozolek, J. & Hackam, D., Apr 1 2013, In : Journal of Immunology. 190, 7, p. 3541-3551 11 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Enterocytes
Autophagy
Intestinal Mucosa
Stress Fibers

Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice

Nace, G. W., Huang, H., Klune, J. R., Eid, R. E., Rosborough, B. R., Korff, S., Li, S., Shapiro, R. A., Stolz, D. B., Sodhi, C., Hackam, D., Geller, D. A., Billiar, T. R. & Tsung, A., Jul 2013, In : Hepatology. 58, 1, p. 374-387 14 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Reperfusion Injury
Hepatocytes
Liver
Myeloid Cells

Discovery and Validation of a New Class of Small Molecule Toll-Like Receptor 4 (TLR4) Inhibitors

Neal, M. D., Jia, H., Eyer, B., Good, M., Guerriero, C. J., Sodhi, C., Afrazi, A., Prindle, T., Ma, C., Branca, M., Ozolek, J., Brodsky, J. L., Wipf, P. & Hackam, D., Jun 12 2013, In : PLoS One. 8, 6, e65779.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Molecules
enterocolitis
Necrotizing Enterocolitis
lipopolysaccharides

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling

Yazji, I., Sodhi, C., Lee, E. K., Good, M., Egan, C. E., Afrazi, A., Neal, M. D., Jia, H., Lin, J., Ma, C., Branca, M. F., Prindle, T., Richardson, W. M., Ozolek, J., Billiar, T. R., Binion, D. G., Gladwin, M. T. & Hackam, D., Jun 4 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 23, p. 9451-9456 6 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Nitric Oxide Synthase Type III
Nitrites
Perfusion

Innate immune signaling in the pathogenesis of necrotizing enterocolitis

Hackam, D., Afrazi, A., Good, M. & Sodhi, C., 2013, In : Clinical and Developmental Immunology. 2013, 475415.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Intestinal Mucosa
CD14 Antigens
HSP70 Heat-Shock Proteins

Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of tlr4 during sepsis

Deng, M., Scott, M. J., Loughran, P., Gibson, G., Sodhi, C., Watkins, S., Hackam, D. & Billiar, T. R., May 15 2013, In : Journal of Immunology. 190, 10, p. 5152-5160 9 p.

Research output: Contribution to journalArticle

Lipopolysaccharides
Sepsis
Punctures
Anti-Bacterial Agents
Ligation
Necrotizing Enterocolitis
Toll-Like Receptors
Toll-Like Receptor 4
Premature Infants
Bacterial Translocation
2012

Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium

Good, M., Siggers, R. H., Sodhi, C., Afrazi, A., Alkhudari, F., Egan, C. E., Neal, M. D., Yazji, I., Jia, H., Lin, J., Branca, M. F., Ma, C., Prindle, T., Grant, Z., Shah, S., Slagle, D., Paredes, J., Ozolek, J., Gittes, G. K. & Hackam, D., Jul 10 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11330-11335 6 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Amniotic Fluid
Intestinal Mucosa
Necrotizing Enterocolitis
Epidermal Growth Factor Receptor

Intestinal epithelial toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice

Sodhi, C., Neal, M. D., Siggers, R., Sho, S., Ma, C., Branca, M. F., Prindle, T., Russo, A. M., Afrazi, A., Good, M., Browersinning, R., Firek, B., Morowitz, M. J., Ozolek, J. A., Gittes, G. K., Billiar, T. R. & Hackam, D., Sep 2012, In : Gastroenterology. 143, 3

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Goblet Cells
Bile Acids and Salts
Enterocytes

Intracellular heat shock protein-70 negatively regulates TLR4 signaling in the newborn intestinal epithelium

Afrazi, A., Sodhi, C., Good, M., Jia, H., Siggers, R., Yazji, I., Ma, C., Neal, M. D., Prindle, T., Grant, Z. S., Branca, M. F., Ozolek, J., Chang, E. B. & Hackam, D., May 1 2012, In : Journal of Immunology. 188, 9, p. 4543-4557 15 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Intestinal Mucosa
Necrotizing Enterocolitis
Newborn Infant
Enterocytes

Novel role for the innate immune receptor toll-like receptor 4 (TLR4) in the regulation of the wnt signaling pathway and photoreceptor apoptosis

Yi, H., Patel, A. K., Sodhi, C., Hackam, D. & Hackam, A. S., May 17 2012, In : PLoS One. 7, 5, e36560.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Wnt Signaling Pathway
photoreceptors
apoptosis
Apoptosis

Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis

Neal, M. D., Sodhi, C., Jia, H., Dyer, M., Egan, C. E., Yazji, I., Good, M., Afrazi, A., Marino, R., Slagle, D., Ma, C., Branca, M. F., Prindle, T., Grant, Z., Ozolek, J. & Hackam, D., Oct 26 2012, In : Journal of Biological Chemistry. 287, 44, p. 37296-37308 13 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Stem cells
Modulators
Necrotizing Enterocolitis
Stem Cells

WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury

Li, H. H., Li, Q., Liu, P., Liu, Y., Li, J., Wasserloos, K., Chao, W., You, M., Oury, T. D., Sodhi, C., Hackam, D., Billiar, T. R., Leikauf, G. D., Pitt, B. R. & Zhang, L. M., Oct 2012, In : American Journal of Respiratory Cell and Molecular Biology. 47, 4, p. 528-535 8 p.

Research output: Contribution to journalArticle

Ventilator-Induced Lung Injury
Tidal Volume
Genes
Capillary Permeability
Macrophages