Charles Jr Steenbergen

Professor

1976 …2020

Research output per year

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Research Output

2006

Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel α1 subunit and reduced ischemia/reperfusion injury

Sun, J., Picht, E., Ginsburg, K. S., Bers, D. M., Steenbergen, C. & Murphy, E., Feb 1 2006, In : Circulation research. 98, 3, p. 403-411 9 p.

Research output: Contribution to journalArticle

S-nitrosylation: NO-related redox signaling to protect against oxidative stress

Sun, J., Steenbergen, C. & Murphy, E., Sep 1 2006, In : Antioxidants and Redox Signaling. 8, 9-10, p. 1693-1705 13 p.

Research output: Contribution to journalReview article

2005

Bcl-2 regulation of mitochondrial energetics

Murphy, E., Imahashi, K. I. & Steenbergen, C., Nov 2005, In : Trends in Cardiovascular Medicine. 15, 8, p. 283-290 8 p.

Research output: Contribution to journalArticle

Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injury

Imahashi, K., Pott, C., Goldhaber, J. I., Steenbergen, C., Philipson, K. D. & Murphy, E., Oct 28 2005, In : Circulation research. 97, 9, p. 916-921 6 p.

Research output: Contribution to journalArticle

Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury

Gabel, S. A., Walker, V. R., London, R. E., Steenbergen, C., Korach, K. S. & Murphy, E., Feb 2005, In : Journal of Molecular and Cellular Cardiology. 38, 2, p. 289-297 9 p.

Research output: Contribution to journalArticle

Estrogen receptor-β mediates male-female differences in the development of pressure overload hypertrophy

Skavdahl, M., Steenbergen, C., Clark, J., Myers, P., Demianenko, T., Mao, L., Rockman, H. A., Korach, K. S. & Murphy, E., Feb 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 288, 2 57-2, p. H469-H476

Research output: Contribution to journalArticle

Graft vascular disease after cardiac transplantation and its relationship to mean acute rejection score

Alexander, R. T., Lathrop, S., Vollmer, R., Blue, L., Russell, S. D. & Steenbergen, C., Oct 1 2005, In : Archives of Pathology and Laboratory Medicine. 129, 10, p. 1283-1287 5 p.

Research output: Contribution to journalArticle

Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: Role of protein kinase C and phosphatidylinositol 3-kinase signaling

Hanlon, P. R., Fu, P., Wright, G. L., Steenbergen, C., Arcasoy, M. O. & Murphy, E., Aug 1 2005, In : FASEB Journal. 19, 10, p. 1323-1325 3 p.

Research output: Contribution to journalArticle

Protein kinase C and preconditioning: Role of the sarcoplasmic reticulum

Yamamura, K., Steenbergen, C. & Murphy, E., Dec 1 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 289, 6 58-6, p. H2484-H2490

Research output: Contribution to journalArticle

Recurrence of cardiac sarcoidosis in a heart transplant recipient

Yager, J. E. E., Hernandez, A. F., Steenbergen, C., Persing, B., Russell, S. D., Milano, C. & Felker, G. M., Nov 1 2005, In : Journal of Heart and Lung Transplantation. 24, 11, p. 1988-1990 3 p.

Research output: Contribution to journalArticle

The role of β-adrenergic receptor signaling in cardioprotection

Tong, H., Bernstein, D., Murphy, E. & Steenbergen, C., Jun 1 2005, In : FASEB Journal. 19, 8, p. 983-985 3 p.

Research output: Contribution to journalArticle

2004

Dose dependent effects of cardiac β 2 adrenoceptor gene therapy

Jones, J. M., Wilson, K. H., Steenbergen, C., Koch, W. J. & Milano, C. A., Nov 1 2004, In : Journal of Surgical Research. 122, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

Erythropoiet in receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury

Wright, G. L., Hanlon, P., Amin, K., Steenbergen, C., Murphy, E. & Arcasoy, M. O., Jun 1 2004, In : FASEB Journal. 18, 9, p. 1031-1033 3 p.

Research output: Contribution to journalArticle

G Protein-Coupled Receptor Internalization Signaling Is Required for Cardioprotection in Ischemic Preconditioning

Tong, H., Rockman, H. A., Koch, W. J., Steenbergen, C. & Murphy, E., Apr 30 2004, In : Circulation research. 94, 8, p. 1133-1141 9 p.

Research output: Contribution to journalArticle

Male/female differences in intracellular Na+regulation during ischemia/reperfusion in mouse heart

Imahashi, K., London, R. E., Steenbergen, C. & Murphy, E., Sep 1 2004, In : Journal of Molecular and Cellular Cardiology. 37, 3, p. 747-753 7 p.

Research output: Contribution to journalArticle

Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury

Imahashi, K., Schneider, M. D., Steenbergen, C. & Murphy, E., Oct 1 2004, In : Circulation research. 95, 7, p. 734-741 8 p.

Research output: Contribution to journalArticle

β 2 Adrenoceptor gene therapy ameliorates left ventricular dysfunction following cardiac surgery

Jones, J. M., Petrofski, J. A., Wilson, K. H., Steenbergen, C., Koch, W. J. & Milano, C. A., Dec 1 2004, In : European Journal of Cardio-thoracic Surgery. 26, 6, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

2003

Ablation of PLB exacerbates ischemic injury to a lesser extent in female than male mice: Protective role of NO

Cross, H. R., Kranias, E. G., Murphy, E. & Steenbergen, C., Feb 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 2 53-2, p. H683-H690

Research output: Contribution to journalArticle

Alterations in apoptotic signaling in human idiopathic cardiomyopathic hearts in failure

Steenbergen, C., Afshari, C. A., Petranka, J. G., Collins, J., Martin, K., Bennett, L., Haugen, A., Bushel, P. & Murphy, E., Jan 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 1 53-1, p. H268-H276

Research output: Contribution to journalArticle

Cause of death and sudden cardiac death after heart transplantation: An autopsy study

Alexander, R. T. & Steenbergen, C. J., May 1 2003, In : American Journal of Clinical Pathology. 119, 5, p. 740-748 9 p.

Research output: Contribution to journalArticle

Cause of death and sudden cardiac death after heart transplantation: An autopsy study

Alexander, R. T. & Steenbergen, C. J., May 1 2003, In : American Journal of Clinical Pathology. 119, 5, p. 740-748 9 p.

Research output: Contribution to journalArticle

Gender differences in sarcoplasmic reticulum calcium loading after isoproterenol

Chen, J., Petranka, J., Yamamura, K., London, R. E., Steenbergen, C. & Murphy, E., Dec 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 285, 6 54-6, p. H2657-H2662

Research output: Contribution to journalArticle

Preconditioning: Is the Akt-ion in the PI3K pathway?

Murphy, E., Tong, H. & Steenbergen, C., Sep 1 2003, In : Journal of Molecular and Cellular Cardiology. 35, 9, p. 1021-1025 5 p.

Research output: Contribution to journalEditorial

2002

Expression of activated PKC epsilon (PKCε) protects the ischemic heart, without attenuating ischemic H+ production

Cross, H. R., Murphy, E., Bolli, R., Ping, P. & Steenbergen, C., Mar 1 2002, In : Journal of Molecular and Cellular Cardiology. 34, 3, p. 361-367 7 p.

Research output: Contribution to journalArticle

Is Na/Ca exchange during ischemia and reperfusion beneficial or detrimental?

Murphy, E., Cross, H. R. & Steenbergen, C., Jan 1 2002, In : Annals of the New York Academy of Sciences. 976, p. 421-430 10 p.

Research output: Contribution to journalArticle

Male and female mice overexpressing the β2-adrenergic receptor exhibit differences in ischemia/reperfusion injury: Role of nitric oxide

Cross, H. R., Murphy, E., Koch, W. J. & Steenbergen, C., Feb 15 2002, In : Cardiovascular research. 53, 3, p. 662-671 10 p.

Research output: Contribution to journalArticle

Overexpression of A3 adenosine receptors decreases heart rate, preserves energetics, and protects ischemic hearts

Cross, H. R., Murphy, E., Black, R. G., Auchampach, J. & Steenbergen, C., Oct 1 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 283, 4 52-4, p. H1562-H1568

Research output: Contribution to journalArticle

Phosphorylation of glycogen synthase kinase-3β during preconditioning through a phosphatidylinositol-3-kinase-dependent pathway is cardioprotective

Tong, H., Imahashi, K., Steenbergen, C. & Murphy, E., Mar 8 2002, In : Circulation research. 90, 4, p. 377-379 3 p.

Research output: Contribution to journalArticle

2001

Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism

Forbes, R. A., Steenbergen, C. & Murphy, E., Apr 27 2001, In : Circulation research. 88, 8, p. 802-809 8 p.

Research output: Contribution to journalArticle

Open Access

Histological evidence of angiogenesis 9 months after transmyocardial laser revascularization

Domkowski, P. W., Biswas, S. S., Steenbergen, C. & Lowe, J. E., Jan 23 2001, In : Circulation. 103, 3, p. 469-471 3 p.

Research output: Contribution to journalArticle

Open Access

Inhibition of p38 MAPK α/β reduces ischemic injury and does not block protective effects of preconditioning

Schneider, S., Chen, W., Hou, J., Steenbergen, C. & Murphy, E., Feb 1 2001, In : American Journal of Physiology - Heart and Circulatory Physiology. 280, 2 49-2, p. H499-H508

Research output: Contribution to journalArticle

Leukocyte-type 12-lipoxygenase-deficient mice show impaired ischemic preconditioning-induced cardioprotection

Gabel, S. A., London, R. E., Funk, C. D., Steenbergen, C. & Murphy, E., May 2001, In : American Journal of Physiology - Heart and Circulatory Physiology. 280, 5 49-5, p. H1963-H1969

Research output: Contribution to journalArticle

2000

An experimental model of chronic myocardial hibernation

St. Louis, J. D., Chad Hughes, G., Kypson, A. P., DeGrado, T. R., Donovan, C. L., Edward Coleman, R., Yin, B., Steenbergen, C., Landolfo, K. P. & Lowe, J. E., May 1 2000, In : Annals of Thoracic Surgery. 69, 5, p. 1351-1357 7 p.

Research output: Contribution to journalArticle

Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C

Tong, H., Chen, W., Steenbergen, C. & Murphy, E., Aug 18 2000, In : Circulation research. 87, 4, p. 309-315 7 p.

Research output: Contribution to journalArticle

Preconditioning enhanced glucose uptake is mediated by p38 MAP kinase not by phosphatidylinositol 3-kinase

Tong, H., Chen, W., London, R. E., Murphy, E. & Steenbergen, C., Apr 21 2000, In : Journal of Biological Chemistry. 275, 16, p. 11981-11986 6 p.

Research output: Contribution to journalArticle

1999

Lipoxygenase metabolism of arachidonic acid in ischemic preconditioning and PKC-induced protection in heart

Chen, W., Glasgow, W., Murphy, E. & Steenbergen, C., Jun 1 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 276, 6 45-6, p. H2094-H2101

Research output: Contribution to journalArticle

Lipoxygenase metabolism of arachidonic acid in ischémic preconditioning and PKC-induced protection in heart

Chen, W., Glasgow, W., Murphy, E. & Steenbergen, C., Dec 1 1999, In : American Journal of Physiology. 276, 6 PART 2, p. H2102-H2108

Research output: Contribution to journalArticle

Na+/H+ and Na+/Ca2+ exchange: Their role in the rise in cytosolic free [Ca2+] during ischaemia and reperfusion

Murphy, E., Cross, H. R. & Steenbergen, C., Jul 13 1999, In : European Heart Journal, Supplement. 1, K, p. K18-K30

Research output: Contribution to journalArticle

Open Access

Sodium regulation during ischemia versus reperfusion and its role in injury

Murphy, E., Cross, H. & Steenbergen, C., Jun 25 1999, In : Circulation research. 84, 12, p. 1469-1470 2 p.

Research output: Contribution to journalEditorial

Open Access
1998

Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice

Cross, H. R., Lu, L., Steenbergen, C., Philipson, K. D. & Murphy, E., Dec 14 1998, In : Circulation research. 83, 12, p. 1215-1223 9 p.

Research output: Contribution to journalArticle

Open Access

Regulation of the Ca2+ gradient across the sarcoplasmic reticulum in perfused rabbit heart: A 19F nuclear magnetic resonance study

Chen, W., London, R., Murphy, E. & Steenbergen, C., Nov 2 1998, In : Circulation research. 83, 9, p. 898-907 10 p.

Research output: Contribution to journalArticle

Open Access
1997

CYP2J subfamily cytochrome P450s in the gastrointestinal tract: Expression, localization, and potential functional significance

Zeldin, D. C., Foley, J., Goldsworthy, S. M., Cook, M. E., Boyle, J. E., Ma, J., Moomaw, C. R., Tomer, K. B., Steenbergen, C. & Wu, S., Jun 1997, In : Molecular Pharmacology. 51, 6, p. 931-943 13 p.

Research output: Contribution to journalArticle

Decreased intracellular pH is not due to increased H + extrusion in preconditioned rat hearts

Gabel, S. A., Cross, H. R., London, R. E., Steenbergen, C. & Murphy, E., Dec 9 1997, In : American Journal of Physiology - Heart and Circulatory Physiology. 273, 5 42-5, p. H2257-H2262

Research output: Contribution to journalArticle

Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes

Wu, S., Chen, W., Murphy, E., Gabel, S., Tomer, K. B., Foley, J., Steenbergen, C., Falck, J. R., Moomaw, C. R. & Zeldin, D. C., May 9 1997, In : Journal of Biological Chemistry. 272, 19, p. 12551-12559 9 p.

Research output: Contribution to journalArticle

Predominant expression of an arachidonate epoxygenase in islets of langerhans cells in human and rat pancreas

Zeldin, D. C., Foley, J., Boyle, J. E., Moomaw, C. R., Tomer, K. B., Parker, C., Steenbergen, C. & Wu, S., Jan 1 1997, In : Endocrinology. 138, 3, p. 1338-1346 9 p.

Research output: Contribution to journalArticle

Open Access