Research output per year
Research output per year
- 43 results
Search results
-
2023
Longitudinal characterization of circulating extracellular vesicles and small RNA during simian immunodeficiency virus infection and antiretroviral therapy
Huang, Y., Liao, Z., Dang, P., Queen, S., Abreu, C. M., Gololobova, O., Zheng, L. & Witwer, K. W., Apr 1 2023, In: AIDS. 37, 5, p. 733-744 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Monocyte-derived macrophages contain persistent latent HIV reservoirs
Veenhuis, R. T., Abreu, C. M., Costa, P. A. G., Ferreira, E. A., Ratliff, J., Pohlenz, L., Shirk, E. N., Rubin, L. H., Blankson, J. N., Gama, L. & Clements, J. E., May 2023, In: Nature microbiology. 8, 5, p. 833-844 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Quantitative Viral Outgrowth Assay to Measure the Functional SIV Reservoir in Myeloid Cells
Abreu, C. M., Veenhuis, R. T., Shirk, E. N., Queen, S. E., Bullock, B. T., Mankowski, J. L., Gama, L. & Clements, J. E., 2022, Methods in Molecular Biology. Humana Press Inc., p. 333-356 24 p. (Methods in Molecular Biology; vol. 2407).Research output: Chapter in Book/Report/Conference proceeding › Chapter
-
Viral load is associated with mitochondrial dysfunction and altered monocyte phenotype in acute severe SARS-CoV-2 infection
Romão, P. RT., Teixeira, P. C., Schipper, L., da Silva, I., Santana Filho, P., Júnior, L. C. R., Peres, A., Gonçalves da Fonseca, S., Chagas Monteiro, M., Lira, F. S., Andrey Cipriani Frade, M., Comerlato, J., Comerlato, C., Sant'Anna, F. H., Bessel, M., Abreu, C. M., Wendland, E. M. & Dorneles, G. P., Jul 2022, In: International immunopharmacology. 108, 108697.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Higher circulating intermediate monocytes are associated with cognitive function in women with HIV
Veenhuis, R. T., Williams, D. W., Shirk, E. N., Abreu, C. M., Ferreira, E. A., Coughlin, J. M., Brown, T. T., Maki, P. M., Anastos, K., Berman, J. W., Clements, J. E. & Rubin, L. H., Jun 8 2021, In: JCI Insight. 6, 11, e146215.Research output: Contribution to journal › Article › peer-review
Open Access -
HIV replication and latency in monocytes and macrophages
Veenhuis, R. T., Abreu, C. M., Shirk, E. N., Gama, L. & Clements, J. E., Jan 2021, In: Seminars in immunology. 51, 101472.Research output: Contribution to journal › Review article › peer-review
-
2019
A Quantitative Approach to SIV Functional Latency in Brain Macrophages
Abreu, C., Shirk, E. N., Queen, S. E., Mankowski, J. L., Gama, L. & Clements, J. E., Mar 15 2019, In: Journal of Neuroimmune Pharmacology. 14, 1, p. 23-32 10 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Brain macrophages harbor latent, infectious simian immunodeficiency virus
Abreu, C., Shirk, E. N., Queen, S. E., Beck, S. E., Mangus, L. M., Pate, K. A. M., Mankowski, J. L., Gama, L. & Clements, J. E., Dec 1 2019, In: AIDS. 33, p. S181-S188Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Infectious virus persists in CD4+ T cells and macrophages in antiretroviral therapy-suppressed simian immunodeficiency virus-infected macaques
Abreu, C. M., Veenhuis, R. T., Avalos, C. R., Graham, S., Queen, S. E., Shirk, E. N., Bullock, B. T., Li, M., Metcalf Pate, K. A., Beck, S. E., Mangus, L. M., Mankowski, J. L., Clements, J. E. & Gama, L., 2019, In: Journal of virology. 93, 15, e00065-19.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Myeloid and CD4 T cells comprise the latent reservoir in antiretroviral therapy-suppressed SIVmac251-infected macaques
Abreu, C. M., Veenhuis, R. T., Avalos, C. R., Graham, S., Parrilla, D. R., Ferreira, E. A., Queen, S. E., Shirk, E. N., Bullock, B. T., Li, M., Pate, K., Beck, S., Mangus, L., Mankowski, J. L., Gabhann, F. M., O’Connor, S. L., Gama, L. & Clementsa, J. E., 2019, In: mBio. 10, 4, e01659-19.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2018
An SIV/macaque model targeted to study HIV-associated neurocognitive disorders
Beck, S. E., Queen, S. E., Metcalf Pate, K. A., Mangus, L. M., Abreu, C. M., Gama, L., Witwer, K. W., Adams, R. J., Zink, M. C., Clements, J. E. & Mankowski, J. L., Oct 3 2018, In: Journal of neurovirology. 24, 2, p. 204-212 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres
Abreu, C. M., Gama, L., Krasemann, S., Chesnut, M., Odwin-Dacosta, S., Hogberg, H. T., Hartung, T. & Pamies, D., Mar 29 2018, In: Frontiers in Microbiology. 9, 2766.Research output: Contribution to journal › Article › peer-review
Open Access -
SIV Latency in Macrophages in the CNS
Gama, L., Abreu, C., Shirk, E. N., Queen, S. E., Beck, S. E., Metcalf Pate, K. A., Bullock, B. T., Zink, M. C., Mankowski, J. L. & Clements, J. E., 2018, Current Topics in Microbiology and Immunology. Springer Verlag, p. 111-130 20 p. (Current Topics in Microbiology and Immunology; vol. 417).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access13 Scopus citations -
2017
Brain macrophages in simian immunodeficiency virus-infected, antiretroviral-suppressed macaques: A functional latent reservoir
Avalos, C. R., Abreu, C. M., Queen, S. E., Li, M., Price, S., Shirk, E. N., Engle, E. L., Forsyth, E., Bullock, B. T., Gabhann, F. M., Wietgrefe, S. W., Haase, A. T., Zink, M. C., Mankowski, J. L., Clements, J. E. & Gama, L., Jul 1 2017, In: mBio. 8, 4, e01186-17.Research output: Contribution to journal › Article › peer-review
Open Access73 Scopus citations -
Identification of novel resistance-related polymorphisms in HIV-1 subtype C RT connection and RNase H domains from patients under virological failure in Brazil
Barral, M. F. M., Sousa, A. K. P., Santos, A. F., Abreu, C. M., Tanuri, A. & Soares, M. A., May 2017, In: AIDS research and human retroviruses. 33, 5, p. 465-471 7 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques
Gama, L., Abreu, C. M., Shirk, E. N., Price, S. L., Li, M., Laird, G. M., Metcalf Pate, K. A., Wietgrefe, S. W., O'Connor, S. L., Pianowski, L., Haase, A. T., Van Lint, C. & Siliciano, R. F., 2017, In: AIDS. 31, 1, p. 5-14 10 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
2016
Development of a rapid phenotypic test for HCV protease inhibitors with potential use in clinical decisions
Pessoa, L. S., Vidal, L. L., da Costa, E. C. B., Abreu, C. M., da Cunha, R. D., Valadão, A. L. C., dos Santos, A. F. & Tanuri, A., Jul 1 2016, In: Genetics and Molecular Biology. 39, 3, p. 358-364 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Follow-up on long-term antiretroviral therapy for cats infected with feline immunodeficiency virus
de Oliveira Medeiros, S., Abreu, C. M., Delvecchio, R., Ribeiro, A. P., Vasconcelos, Z., de Moraes Brindeiro, R. & Tanuri, A., 2016, In: Journal of Feline Medicine and Surgery. 18, 4, p. 264-272 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2015
Natural plant alkaloid (Emetine) inhibits HIV-1 replication by interfering with reverse transcriptase activity
Valadão, A. L. C., Abreu, C. M., Dias, J. Z., Arantes, P., Verli, H., Tanuri, A. & De Aguiar, R. S., Jun 1 2015, In: Molecules. 20, 6, p. 11474-11489 16 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Short Communication: In Vitro Accumulation of Drug Resistance Mutations in Chimeric Infectious Clones Containing Subtype B or C Reverse Transcriptase and Selected with Tenofovir or Didanosine
Cunha, R. D., Abreu, C. M., Sousa, A. K. P., Mabombo, V. C. J., Nijhuis, M., De Jong, D. & Tanuri, A., Aug 1 2015, In: AIDS research and human retroviruses. 31, 8, p. 851-858 8 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Trends in Prevalence of HIV-1 Drug Resistance in a Public Clinic in Maputo, Mozambique
Bila, D. C. A., Boullosa, L. T., Vubil, A. S., Mabunda, N. J., Abreu, C. M., Ismael, N., Jani, I. V. & Tanuri, A., 2015, In: PloS one. 10, 7, p. e0130580Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2014
Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: Inhibition of de novo infection and activation of viral LTR
Abreu, C. M., Price, S. L., Shirk, E. N., Cunha, R. D., Pianowski, L. F., Clements, J. E., Tanuri, A. & Gama, L., May 14 2014, In: PloS one. 9, 5, e97257.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Genetic analysis and natural polymorphisms in HIV-1 gp41 isolates from Maputo City, Mozambique
Ismael, N., Bila, D., Mariani, D., Vubil, A., Mabunda, N., Abreu, C., Jani, I. & Tanuri, A., Jun 1 2014, In: AIDS research and human retroviruses. 30, 6, p. 603-609 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
HIV-1 Nef inhibits protease activity and its absence alters protein content of mature viral particles
Mendonça, L. M., Poeys, S. C., Abreu, C. M., Tanuri, A. & Costa, L. J., Apr 18 2014, In: PloS one. 9, 4, e95352.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Reactivation of latent HIV-1 by new semi-synthetic ingenol esters
Pandeló José, D., Bartholomeeusen, K., da Cunha, R. D., Abreu, C. M., Glinski, J., da Costa, T. B. F., Bacchi Rabay, A. F. M., Pianowski Filho, L. F., Dudycz, L. W., Ranga, U., Peterlin, B. M., Pianowski, L. F., Tanuri, A. & Aguiar, R. S., Aug 2014, In: Virology. 462-463, 1, p. 328-339 12 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
2013
Evolution of Primary HIV Drug Resistance in a Subtype C Dominated Epidemic in Mozambique
Bila, D. C. A., Young, P., Merks, H., Vubil, A. S., Mahomed, M., Augusto, A., Abreu, C. M., Mabunda, N. J., Brooks, J. I., Tanuri, A. & Jani, I. V., Jul 30 2013, In: PloS one. 8, 7, e68213.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2012
Differential In Vitro Kinetics of Drug Resistance Mutation Acquisition in HIV-1 RT of Subtypes B and C
Cunha, R. D., Abreu, C. M., Gonzalez, L. M. F., Nijhuis, M., de Jong, D., Aguiar, R. S., Afonso, A. O., Brindeiro, R. M. & Tanuri, A., Oct 3 2012, In: PloS one. 7, 10, e46622.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Genetic diversity and naturally polymorphisms in HIV type 1 integrase isolates from Maputo, Mozambique: Implications for integrase inhibitors
Oliveira, M. F., Ramalho, D. B., Abreu, C. M., Vubil, A., Mabunda, N., Ismael, N., Francisco, C., Jani, I. V. & Tanuri, A., Dec 1 2012, In: AIDS research and human retroviruses. 28, 12, p. 1788-1792 5 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2011
Frequency of human immunodeficiency virus type-2 in hiv infected patients in Maputo City, Mozambique
Maueia, C., Costa, D., Meggi, B., Ismael, N., Walle, C., Curvo, R., Abreu, C., Bhatt, N., Tanuri, A., Jani, I. V. & Ferreira, O. C., 2011, In: Virology Journal. 8, 408.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Genetic characterization of human T-cell lymphotropic virus type 1 in mozambique: Transcontinental lineages drive the HTLV-1 endemic
Vicente, A. C. P., Gudo, E. S., Iñiguez, A. M., Otsuki, K., Bhatt, N., Abreu, C. M., Vubil, A., Bila, D., Ferreira, O. C., Tanuri, A. & Jani, I. V., Apr 2011, In: PLoS neglected tropical diseases. 5, 4, e1038.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Genotypic analysis of the gp41 HR1 region from HIV-1 isolates from enfuvirtide-treated and untreated patients
Pessoa, L. S., Valadão, A. L. C., Abreu, C. M., Calazans, A. R., Martins, A. N., Azevedo, S. S. S. D., Couto-Fernandez, J. C., Azevedo, M. C. M. V. & Tanuri, A., Aug 15 2011, In: Journal of Acquired Immune Deficiency Syndromes. 57, SUPPL. 3, p. S197-S201Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2010
Effect of serine-type protease of Candida spp. isolated from linear gingival erythema of HIV-positive children: Critical factors in the colonization
Portela, M. B., Souza, I. P. R., Abreu, C. M., Bertolini, M., Holandino, C., Alviano, C. S., Santos, A. L. S. & Soares, R. M. A., Nov 2010, In: Journal of Oral Pathology and Medicine. 39, 10, p. 753-760 8 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
2009
Co-infection by human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type 1 (HTLV-1): Does immune activation lead to a faster progression to AIDS?
Gudo, E. S., Bhatt, N. B., Bila, D. R., Abreu, C. M., Tanuri, A., Savino, W., Silva-Barbosa, S. D. & Jani, I. V., Dec 22 2009, In: BMC infectious diseases. 9, 211.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Serologic and molecular typing of human T-lymphotropic virus among blood donors in Maputo City, Mozambique
Jani, I. V., Gudo, E. S., Abreu, C. M., Mussá, T., Do Rosário Augusto, Â., Otsuki, K., Chambo, E., Amade, N., Tanuri, A. & Ferreira, O. C., Jun 2009, In: Transfusion. 49, 6, p. 1146-1150 5 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2008
Genotypic and phenotypic characterization of human immunodeficiency virus type 1 isolates circulating in pregnant women from Mozambique
Abreu, C. M., Brindeiro, P. A., Martins, A. N., Arruda, M. B., Bule, E., Stakteas, S., Tanuri, A. & De Moraes Brindeiro, R., Nov 2008, In: Archives of Virology. 153, 11, p. 2013-2017 5 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
The compound 6-chloro-1,4-dihydro-4-oxo-1(β-D-Ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase
Souza, T. M. L., Cirne-Santos, C. C., Rodrigues, D. Q., Abreu, C. M., Tanuri, A., Ferreira, V. F., Marques, I. P., Vieira de Souza, M. C. B., Leite Fontes, C. F., de Palmer Paixão Frugulhetti, I. C. & Bou-Habib, D. C., May 2008, In: Current HIV research. 6, 3, p. 209-217 9 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations -
The dolabellane diterpene Dolabelladienetriol is a typical noncompetitive inhibitor of HIV-1 reverse transcriptase enzyme
Cirne-Santos, C. C., Souza, T. M. L., Teixeira, V. L., Fontes, C. F. L., Rebello, M. A., Castello-Branco, L. R. R., Abreu, C. M., Tanuri, A., Frugulhetti, I. C. P. P. & Bou-Habib, D. C., Jan 2008, In: Antiviral Research. 77, 1, p. 64-71 8 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
2005
Use of proteolytic enzymes as an additional tool for trypanosomatid identification
Santos, A. L. S., Abreu, C. M., Alviano, C. S. & Soares, R. M. A., Jan 2005, In: Parasitology. 130, 1, p. 79-88 10 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
2004
Impact of nelfinavir resistance mutations on in vitro phenotype, fitness, and replication capacity of human immunodeficiency virus type 1 with subtype B and C proteases
Gonzalez, L. M. F., Brindeiro, R. M., Aguiar, R. S., Pereira, H. S., Abreu, C. M., Soares, M. A. & Tanuri, A., Sep 2004, In: Antimicrobial agents and chemotherapy. 48, 9, p. 3552-3555 4 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2003
Heterogeneity of metallo and serine extracellular proteinases in oral clinical isolates of Candida albicans in HIV-positive and healthy children from Rio de Janeiro, Brazil
Costa, E. M. M. D. B., Dos Santos, A. L. S., Cardoso, A. S., Portela, M. B., Abreu, C. M., Alviano, C. S., Hagler, A. N. & Soares, R. M. D. A., Sep 22 2003, In: FEMS Immunology and Medical Microbiology. 38, 2, p. 173-180 8 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
2002
Activation of the glycosylphosphatidylinositol-anchored membrane proteinase upon release from Herpetomonas samuelpessoai by phospholipase C
Dos Santos, A. L. S., Abreu, C. M., Alviano, C. S. & De Araújo Soares, R. M., Oct 1 2002, In: Current Microbiology. 45, 4, p. 293-298 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2001
Cell-associated and extracellular proteinases in Blastocrithidia culicis: Influence of growth conditions
Souza dos Santos, A. L., Abreu, C. M., Batista, L. M., Alviano, C. S. & Soares, R. M. D. A., 2001, In: Current Microbiology. 43, 2, p. 100-106 7 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Developmentally regulated protein expression mediated by dimethylsulfoxide in Herpetomonas samuelpessoai
Santos, A. L. S. D., Batista, L. M., Abreu, C. M., Alviano, C. S., Angluster, J. & Soares, R. M. D. A., 2001, In: Current Microbiology. 42, 2, p. 111-116 6 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations