Carolyn E Machamer

Professor

1978 …2019

Research output per year

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Research Output

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2019

A nonapoptotic endothelial barrier-protective role for caspase-3

Suresh, K., Carino, K., Johnston, L., Servinsky, L., Machamer, C. E., Kolb, T. M., Lam, H., Dudek, S. M., An, S., Rane, M. J., Shimoda, L. & Damarla, M., Jun 1 2019, In : American journal of physiology. Lung cellular and molecular physiology. 316, 6, p. L1118-L1126

Research output: Contribution to journalArticle

2018

Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins

Gilbert, C. E., Sztul, E., Machamer, C. E. & Lippincott-Schwartz, J., Apr 15 2018, In : Molecular Biology of the Cell. 29, 8, p. 937-947 11 p.

Research output: Contribution to journalArticle

Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors

Sisk, J. M., Frieman, M. B. & Machamer, C. E., May 1 2018, In : Journal of General Virology. 99, 5, p. 619-630 12 p., 001047.

Research output: Contribution to journalArticle

2016

Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner

Shao, W., Machamer, C. E. & Espenshade, P., Aug 1 2016, In : Journal of Lipid Research. 57, 8, p. 1564-1573 10 p.

Research output: Contribution to journalArticle

2015

A coronavirus E protein is present in two distinct pools with different effects on assembly and the secretory pathway

Westerbeck, J. W. & Machamer, C. E., Jan 1 2015, In : Journal of virology. 89, 18, p. 9313-9323 11 p.

Research output: Contribution to journalArticle

2014

Mitogen-activated protein kinase-activated protein kinase 2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3

Damarla, M., Parniani, A. R., Johnston, L., Maredia, H., Serebreni, L., Hamdan, O., Sidhaye, V. K., Shimoda, L. A., Myers, A. C., Crow, M. T., Schmidt, E. P., Machamer, C. E., Gaestel, M., Rane, M. J., Kolb, T. M., Kim, B. S., Damico, R. L. & Hassoun, P. M., May 2014, In : American journal of respiratory cell and molecular biology. 50, 5, p. 932-941 10 p.

Research output: Contribution to journalArticle

Three basic residues of intracellular loop 3 of the beta-1 adrenergic receptor are required for golgin-160-dependent trafficking

Gilbert, C. E., Zuckerman, D. M., Currier, P. L. & Machamer, C. E., Feb 20 2014, In : International journal of molecular sciences. 15, 2, p. 2929-2945 17 p.

Research output: Contribution to journalArticle

2013

Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase

Taylor, M. S., Ruch, T. R., Hsiao, P. Y., Hwang, Y., Zhang, P., Dai, L., Huang, C. R. L., Berndsen, C. E., Kim, M. S., Pandey, A., Wolberger, C., Marmorstein, R., Machamer, C., Boeke, J. D. & Cole, P. A., Nov 8 2013, In : Journal of Biological Chemistry. 288, 45, p. 32211-32228 18 p.

Research output: Contribution to journalArticle

Golgi protein ACBD3 mediates neurotoxicity associated with huntington's disease

Sbodio, J., Paul, B., Machamer, C. E. & Snyder, S. H., May 12 2013, In : Cell Reports. 4, 5, p. 890-897 8 p.

Research output: Contribution to journalArticle

2012

Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage

Chandran, S. & Machamer, C. E., Mar 1 2012, In : Biochemical Journal. 442, 2, p. 391-401 11 p.

Research output: Contribution to journalArticle

2011

Differential regulation of two palmitoylation sites in the cytoplasmic tail of the β1-adrenergic receptor

Zuckerman, D. M., Hicks, S. W., Charron, G., Hang, H. C. & Machamer, C. E., May 27 2011, In : Journal of Biological Chemistry. 286, 21, p. 19014-19023 10 p.

Research output: Contribution to journalArticle

Identification of a golgi complex-targeting signal in the cytoplasmic tail of the severe acute respiratory syndrome coronavirus envelope protein

Cohen, J. R., Lin, L. D. & Machamer, C. E., Jun 1 2011, In : Journal of virology. 85, 12, p. 5794-5803 10 p.

Research output: Contribution to journalArticle

2010

Ultrastructure and regulation of lateralized connexin43 in the failing heart

Hesketh, G. G., Shah, M. H., Halperin, V. L., Cooke, C. A., Akar, F. G., Yen, T. E., Kass, D. A., Machamer, C. E., Van Eyk, J. E. & Tomaselli, G. F., Apr 2010, In : Circulation Research. 106, 6, p. 1153-1163 11 p.

Research output: Contribution to journalArticle

2008

Acute perturbations in golgi organization impact de novo sphingomyelin synthesis

Chandran, S. & Machamer, C. E., Oct 20 2008, In : Traffic. 9, 11, p. 1894-1904 11 p.

Research output: Contribution to journalArticle

Generating antibodies to the gene 3 proteins of infectious bronchitis virus.

Pendleton, A. R. & Machamer, C. E., 2008, In : Methods in molecular biology (Clifton, N.J.). 454, p. 163-189 27 p.

Research output: Contribution to journalArticle

2007

Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with Golgin-160

Sbodio, J. I. & Machamer, C. E., Oct 12 2007, In : Journal of Biological Chemistry. 282, 41, p. 29874-29881 8 p.

Research output: Contribution to journalArticle

Privileged delivery of polymer nanoparticles to the perinuclear region of live cells via a non-clathrin, non-degradative pathway

Lai, S. K., Hida, K., Man, S. T., Chen, C., Machamer, C., Schroer, T. A. & Hanes, J., Mar 30 2007, In : Biomaterials. 28, 18, p. 2876-2884 9 p.

Research output: Contribution to journalArticle

2006

Differential localization and turnover of infectious bronchitis virus 3b protein in mammalian versus avian cells

Pendleton, A. R. & Machamer, C. E., Feb 20 2006, In : Virology. 345, 2, p. 337-345 9 p.

Research output: Contribution to journalArticle

GCP60 preferentially interacts with a caspase-generated golgin-160 fragment

Sbodio, J. I., Hicks, S. W., Simon, D. & Machamer, C. E., Sep 22 2006, In : Journal of Biological Chemistry. 281, 38, p. 27924-27931 8 p.

Research output: Contribution to journalArticle

Golgin-160 is required for the Golgi membrane sorting of the insulin-responsive glucose transporter GLUT4 in adipocytes

Williams, D., Hicks, S. W., Machamer, C. E. & Pessin, J. E., Dec 2006, In : Molecular Biology of the Cell. 17, 12, p. 5346-5355 10 p.

Research output: Contribution to journalArticle

Golgin-160 promotes cell surface expression of the beta-1 adrenergic receptor

Hicks, S. W., Horn, T. A., Mccaffery, J. M., Zuckerman, D. M. & Machamer, C. E., Dec 1 2006, In : Traffic. 7, 12, p. 1666-1677 12 p.

Research output: Contribution to journalArticle

Inhibition of mixed-lineage kinase (MLK) activity during G2-phase disrupts microtubule formation and mitotic progression in HeLa cells

Cha, H., Dangi, S., Machamer, C. E. & Shapiro, P., Jan 1 2006, In : Cellular Signalling. 18, 1, p. 93-104 12 p.

Research output: Contribution to journalArticle

Transcriptional regulation of RNA3 of infectious bronchitis virus.

Youn, S., Collisson, E. W. & Machamer, C. E., 2006, In : Advances in Experimental Medicine and Biology. 581, p. 109-112 4 p.

Research output: Contribution to journalArticle

Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p

Sesaki, H., Dunn, C. D., Iijima, M., Shepard, K. A., Yaffe, M. P., Machamer, C. E. & Jensen, R. E., Jun 5 2006, In : Journal of Cell Biology. 173, 5, p. 651-658 8 p.

Research output: Contribution to journalArticle

2005

Caspase-resistant golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors

Maag, R. S., Mancini, M., Rosen, A. & Machamer, C. E., Jun 9 2005, In : Molecular biology of the cell. 16, 6, p. 3019-3027 9 p.

Research output: Contribution to journalArticle

Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection

Youn, S., Collisson, E. W. & Machamer, C. E., Nov 2005, In : Journal of Virology. 79, 21, p. 13209-13217 9 p.

Research output: Contribution to journalArticle

Golgi structure in stress sensing and apoptosis

Hicks, S. W. & Machamer, C. E., Jul 10 2005, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1744, 3 SPEC. ISS., p. 406-414 9 p.

Research output: Contribution to journalArticle

Infectious bronchitis virus 3a protein localizes to a novel domain of the smooth endoplasmic reticulum

Pendleton, A. R. & Machamer, C. E., May 1 2005, In : Journal of virology. 79, 10, p. 6142-6151 10 p.

Research output: Contribution to journalArticle

Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST

Hicks, S. W. & Machamer, C. E., Aug 12 2005, In : Journal of Biological Chemistry. 280, 32, p. 28944-28951 8 p.

Research output: Contribution to journalArticle

Targeting of the mitochondrial membrane proteins to the cell surface for functional studies

Ardehali, H., Xue, T., Dong, P. & Machamer, C. E., Dec 16 2005, In : Biochemical and Biophysical Research Communications. 338, 2, p. 1143-1151 9 p.

Research output: Contribution to journalArticle

2004

Intracellular targeting signals contribute to localization of coronavirus spike proteins near the virus assembly site

Lontok, E., Corse, E. & Machamer, C. E., Jun 2004, In : Journal of Virology. 78, 11, p. 5913-5922 10 p.

Research output: Contribution to journalArticle

Phosphorylation of golgin-160 by mixed lineage kinase 3

Cha, H., Smith, B. L., Gallo, K., Machamer, C. E. & Shapiro, P., Feb 15 2004, In : Journal of cell science. 117, 5, p. 751-760 10 p.

Research output: Contribution to journalArticle

2003

The cytoplasmic tails of infectious bronchitis virus E and M proteins mediate their interaction

Corse, E. & Machamer, C. E., Jul 20 2003, In : Virology. 312, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

2002

The cytoplasmic tail of infectious bronchitis virus E protein directs golgi targeting

Corse, E. & Machamer, C. E., Jan 1 2002, In : Journal of virology. 76, 3, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

Open Access

The NH2-terminal domain of golgin-160 contains both Golgi and nuclear targeting information

Golgi, C. B., Information, N. T., Hicks, S. W. & Machamer, C. E., Sep 27 2002, In : Journal of Biological Chemistry. 277, 39, p. 35833-35839 7 p.

Research output: Contribution to journalArticle

2001

Infectious bronchitis virus envelope protein targeting: Implications for virus assembly

Corse, E. & Machamer, C. E., Dec 1 2001, In : Advances in experimental medicine and biology. 494, p. 571-576 6 p.

Research output: Contribution to journalArticle

p38: A novel protein that associates with the vesicular stomatitis virus glycoprotein

Sevier, C. S. & Machamer, C. E., Sep 21 2001, In : Biochemical and Biophysical Research Communications. 287, 2, p. 574-582 9 p.

Research output: Contribution to journalArticle

2000

Caspase-2 is localized at the Golgi complex and cleaves Golgin-160 during apoptosis

Mancini, M., Machamer, C. E., Roy, S., Nicholson, D. W., Thornberry, N. A., Casciola-Rosen, L. A. & Rosen, A., May 1 2000, In : Journal of Cell Biology. 149, 3, p. 603-612 10 p.

Research output: Contribution to journalArticle

Cell surface display and intracellular trafficking of free glycosylphosphatidylinositols in mammalian cells

Baumann, N. A., Vidugiriene, J., Machamer, C. E. & Menon, A. K., Mar 10 2000, In : Journal of Biological Chemistry. 275, 10, p. 7378-7389 12 p.

Research output: Contribution to journalArticle

Infectious bronchitis virus E protein is targeted to the Golgi complex and directs release of virus-like particles

Corse, E. & Machamer, C. E., May 2 2000, In : Journal of virology. 74, 9, p. 4319-4326 8 p.

Research output: Contribution to journalArticle

1998
1997

Ceramide accumulation uncovers a cycling pathway for the cis-Golgi network marker, infectious bronchitis virus M protein

Maceyka, M. & Machamer, C. E., Dec 15 1997, In : Journal of Cell Biology. 139, 6, p. 1411-1418 8 p.

Research output: Contribution to journalArticle